Palmoxiric acid (BioDeep_00000182058)

   

human metabolite blood metabolite


代谢物信息卡片


2-Tetradecylglycidic acid, (+-)-isomer

化学式: C17H32O3 (284.2351)
中文名称: 帕莫酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCC1(CO1)C(=O)O
InChI: InChI=1S/C17H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(15-20-17)16(18)19/h2-15H2,1H3,(H,18,19)

描述信息

C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent
D007004 - Hypoglycemic Agents

同义名列表

9 个代谢物同义名

2-Tetradecylglycidic acid, (+-)-isomer; 2-Tetradecylglycidic acid, (R)-isomer; 2-Tetradecylglycidic acid, (S)-isomer; 2-tetradecyloxirane-2-carboxylic acid; 2-Tetradecyloxiranecarboxylic acid; 2-Tetradecyloxirane-2-carboxylate; 2-Tetradecylglycidic acid; Palmoxiric acid; Palmoxirate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

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  • Aldo Grefhorst, Jildou Hoekstra, Terry G J Derks, D Margriet Ouwens, Julius F W Baller, Rick Havinga, Louis M Havekes, Johannes A Romijn, Folkert Kuipers. Acute hepatic steatosis in mice by blocking beta-oxidation does not reduce insulin sensitivity of very-low-density lipoprotein production. American journal of physiology. Gastrointestinal and liver physiology. 2005 Sep; 289(3):G592-8. doi: 10.1152/ajpgi.00063.2005. [PMID: 15817811]
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  • S I Yamagishi , D Edelstein, X L Du, Y Kaneda, M Guzmán, M Brownlee. Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. The Journal of biological chemistry. 2001 Jul; 276(27):25096-100. doi: 10.1074/jbc.m007383200. [PMID: 11342529]
  • J E Jones, L S Lubbers. Suppression and recovery of estrous behavior in Syrian hamsters after changes in metabolic fuel availability. American journal of physiology. Regulatory, integrative and comparative physiology. 2001 May; 280(5):R1393-8. doi: 10.1152/ajpregu.2001.280.5.r1393. [PMID: 11294759]
  • A Arduini, G Zibellini, L Ferrari, L Magnanimi, S Dottori, A Lohninger, P Carminati. Participation of carnitine palmitoyltransferase in the synthesis of dipalmitoylphosphatidylcholine in rat alveolar type II cells. Molecular and cellular biochemistry. 2001 Feb; 218(1-2):81-6. doi: 10.1023/a:1007221708765. [PMID: 11330841]
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  • I D Caterson, S J Fuller, P J Randle. Effect of the fatty acid oxidation inhibitor 2-tetradecylglycidic acid on pyruvate dehydrogenase complex activity in starved and alloxan-diabetic rats. The Biochemical journal. 1982 Oct; 208(1):53-60. doi: 10.1042/bj2080053. [PMID: 7159398]
  • G F Tutwiler, H J Brentzel. Relation of oxidation of long-chain fatty acids to gluconeogenesis in the perfused liver of the guinea pig: effect of 2-tetradecylglycidic acid (McN-3802). European journal of biochemistry. 1982 Jun; 124(3):465-70. doi: 10.1111/j.1432-1033.1982.tb06616.x. [PMID: 7106101]
  • S M Lee, G Tutwiler, R Bressler, C H Kircher. Metabolic control of prevention of nephropathy by 2-tetradecylglycidate in the diabetic mouse (db/db). Diabetes. 1982 Jan; 31(1):12-8. doi: 10.2337/diab.31.1.12. [PMID: 6759207]