Nitromifene (BioDeep_00000181716)
human metabolite blood metabolite
代谢物信息卡片
化学式: C27H28N2O4 (444.2049)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC=C(C=C1)C(=C(C1=CC=CC=C1)[N+]([O-])=O)C1=CC=C(OCCN2CCCC2)C=C1
InChI: InChI=1S/C27H28N2O4/c1-32-24-13-9-21(10-14-24)26(27(29(30)31)23-7-3-2-4-8-23)22-11-15-25(16-12-22)33-20-19-28-17-5-6-18-28/h2-4,7-16H,5-6,17-20H2,1H3
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- N Sayag, N Snapir, E Arnon, M E el Halawani, V E Grimm, B Robinzon. Sexual differentiation of copulatory behaviour in the male chick requires gonadal steroids.
British poultry science.
1991 Jul; 32(3):607-17. doi:
10.1080/00071669108417386. [PMID: 1893270] - Y M Huet-Hudson, S K Dey. Differential effects of ovarian steroids and triphenylethylene compounds on macromolecular uptake and thymidine incorporation in the mouse uterus.
Journal of steroid biochemistry.
1990 Jan; 35(1):23-7. doi:
10.1016/0022-4731(90)90140-n. [PMID: 2407900] - Y M Huet, S K Dey. A paradoxical effect of an antiestrogen, CI-628, on implantation in the mouse.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1988 Oct; 189(1):61-5. doi:
10.3181/00379727-189-42780. [PMID: 3054903] - J R Pasqualini, C Sumida, N Giambiagi. Pharmacodynamic and biological effects of anti-estrogens in different models.
Journal of steroid biochemistry.
1988 Oct; 31(4B):613-43. doi:
10.1016/0022-4731(88)90013-1. [PMID: 3059059] - P C Ruenitz, J R Bagley. Metabolism of nitromiphene (CI 628) in the immature female rat: role of gastrointestinal microflora in the biotransformation of a triarylethylene antiestrogen.
Cancer research.
1986 Dec; 46(12 Pt 1):6255-9. doi:
NULL. [PMID: 3536077] - J C Eldridge, J A Cidlowski, T G Muldoon. Correlation between LH and estrogen receptor turnover in pituitary and hypothalamus of castrate rats following estrogen agonists and antagonists.
Journal of steroid biochemistry.
1986 Feb; 24(2):623-8. doi:
10.1016/0022-4731(86)90129-9. [PMID: 3517502] - C A Lamartiniere, J M Nicholas, J Hermann, N S Whithworth. Sex-differentiated enzyme levels and oestrogen uptake in adult rats treated neonatally with tamoxifen or CI-628.
Journal of steroid biochemistry.
1986 Feb; 24(2):557-62. doi:
10.1016/0022-4731(86)90119-6. [PMID: 3517501] - Y H Kang, A Sahai, W E Criss, W L West. Ultracytochemical localization of estrogen-stimulated guanylate cyclase in rat uterus.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
1982 Apr; 30(4):331-42. doi:
10.1177/30.4.6120972. [PMID: 6120972] - M A Kneifel, B S Katzenellenbogen. Comparative effects of estrogen and antiestrogen on plasma renin substrate levels and hepatic estrogen receptors in the rat.
Endocrinology.
1981 Feb; 108(2):545-52. doi:
10.1210/endo-108-2-545. [PMID: 7004858] - F Gogan, W H Rotsztejn, L Couturier, G Chazal, I Beattie, C Kordon. Interaction of the anti-estrogen CI-628 and estradiol on plasma LH and hypothalamic LH-RH in the female rat.
Brain research.
1980 Feb; 184(1):109-18. doi:
10.1016/0006-8993(80)90590-9. [PMID: 6986954] - E J Roy, B S McEwen. Oestrogen receptors in cell nuclei of the hypothalamus-preoptic area-amygdala following an injection of oestradiol or the antioestrogen CI-628.
The Journal of endocrinology.
1979 Dec; 83(3):285-93. doi:
10.1677/joe.0.0830285. [PMID: 395264] - J Sengupta, S K Roy, S K Manchanda. Hormonal control of implantation: a possible role of lysosomal function in the embryo-uterus interaction.
Journal of steroid biochemistry.
1979 Jul; 11(1C):729-44. doi:
10.1016/0022-4731(79)90007-4. [PMID: 491641] - W A Chamley, J K Findlay, M E Nairn. The effect of testosterone and an anti-oestrogen on hypertrophy of bulbourethral glands of wethers grazing oestrogenic pastures.
Australian veterinary journal.
1977 Oct; 53(10):476-7. doi:
10.1111/j.1751-0813.1977.tb05466.x. [PMID: 612320] - V L de Vlaming, M J Vodicnik, G Bauer, T Murphy, D Evans. Estradiol-17 beta effects on lipid and carbohydrate metabolism and on the induction of a yolk precursor in goldfish, Carassius auratus.
Life sciences.
1977 Jun; 20(12):1945-52. doi:
10.1016/0024-3205(77)90172-2. [PMID: 881939] - W G Luttge, H E Gray, J R Hughes. Regional and subcellular [3h]estradiol localization in selected brain regions and pituitary of female mice: effects of unlabeled estradiol and various anti-hormones.
Brain research.
1976 Mar; 104(2):273-81. doi:
10.1016/0006-8993(76)90619-3. [PMID: 1260424] - L E Clemens, Y H Shih, H O Brink, M R Callantine. Physiologic significance of 17beta-estradiol binding in the rabbit Fallopian tube.
American journal of obstetrics and gynecology.
1975 May; 122(1):113-22. doi:
10.1016/0002-9378(75)90624-9. [PMID: 165723]
