3-(5-Methoxy-4-oxocyclohex-2-en-1-yl)prop-2-enoic acid (BioDeep_00000181522)
human metabolite blood metabolite
代谢物信息卡片
3-(5-Methoxy-4-oxocyclohex-2-en-1-yl)prop-2-enoic acid
化学式: C10H12O4 (196.0736)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 50%
分子结构信息
SMILES: COC1CC(C=CC(O)=O)C=CC1=O
InChI: InChI=1S/C10H12O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-5,7,9H,6H2,1H3,(H,12,13)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Anila Mathew, Takahiro Fukuda, Yutaka Nagaoka, Takashi Hasumura, Hisao Morimoto, Yasuhiko Yoshida, Toru Maekawa, Kizhikkilot Venugopal, D Sakthi Kumar. Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer's disease.
PloS one.
2012; 7(3):e32616. doi:
10.1371/journal.pone.0032616. [PMID: 22403681] - Karine Redeuil, Candice Smarrito-Menozzi, Philippe Guy, Serge Rezzi, Fabiola Dionisi, Gary Williamson, Kornél Nagy, Mathieu Renouf. Identification of novel circulating coffee metabolites in human plasma by liquid chromatography-mass spectrometry.
Journal of chromatography. A.
2011 Jul; 1218(29):4678-88. doi:
10.1016/j.chroma.2011.05.050. [PMID: 21676405] - Mathieu Renouf, Philippe Guy, Cynthia Marmet, Karin Longet, Anne-Lise Fraering, Julie Moulin, Denis Barron, Fabiola Dionisi, Christophe Cavin, Heike Steiling, Gary Williamson. Plasma appearance and correlation between coffee and green tea metabolites in human subjects.
The British journal of nutrition.
2010 Dec; 104(11):1635-40. doi:
10.1017/s0007114510002709. [PMID: 20691128] - Gary Williamson, Michael N Clifford. Colonic metabolites of berry polyphenols: the missing link to biological activity?.
The British journal of nutrition.
2010 Oct; 104 Suppl 3(?):S48-66. doi:
10.1017/s0007114510003946. [PMID: 20955650] - Angélique Stalmach, Heike Steiling, Gary Williamson, Alan Crozier. Bioavailability of chlorogenic acids following acute ingestion of coffee by humans with an ileostomy.
Archives of biochemistry and biophysics.
2010 Sep; 501(1):98-105. doi:
10.1016/j.abb.2010.03.005. [PMID: 20226754] - Luciano Callipo, Chiara Cavaliere, Valentina Fuscoletti, Riccardo Gubbiotti, Roberto Samperi, Aldo Laganà. Phenilpropanoate identification in young wheat plants by liquid chromatography/tandem mass spectrometry: monomeric and dimeric compounds.
Journal of mass spectrometry : JMS.
2010 Sep; 45(9):1026-40. doi:
10.1002/jms.1800. [PMID: 20690165] - Daniele Del Rio, Angelique Stalmach, Luca Calani, Alan Crozier. Bioavailability of coffee chlorogenic acids and green tea flavan-3-ols.
Nutrients.
2010 08; 2(8):820-33. doi:
10.3390/nu2080820. [PMID: 22254058] - Sonia de Pascual-Teresa, Diego A Moreno, Cristina García-Viguera. Flavanols and anthocyanins in cardiovascular health: a review of current evidence.
International journal of molecular sciences.
2010 Apr; 11(4):1679-703. doi:
10.3390/ijms11041679. [PMID: 20480037] - Philippe A Guy, Mathieu Renouf, Denis Barron, Christophe Cavin, Fabiola Dionisi, Sunil Kochhar, Serge Rezzi, Gary Williamson, Heike Steiling. Quantitative analysis of plasma caffeic and ferulic acid equivalents by liquid chromatography tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Dec; 877(31):3965-74. doi:
10.1016/j.jchromb.2009.10.006. [PMID: 19879819] - Angélique Stalmach, William Mullen, Denis Barron, Kenichi Uchida, Takao Yokota, Christophe Cavin, Heike Steiling, Gary Williamson, Alan Crozier. Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption.
Drug metabolism and disposition: the biological fate of chemicals.
2009 Aug; 37(8):1749-58. doi:
10.1124/dmd.109.028019. [PMID: 19460943] - Magali Cannac, Vanina Pasqualini, Toussaint Barboni, Frederic Morandini, Lila Ferrat. Phenolic compounds of Pinus laricio needles: a bioindicator of the effects of prescribed burning in function of season.
The Science of the total environment.
2009 Jul; 407(15):4542-8. doi:
10.1016/j.scitotenv.2009.04.035. [PMID: 19446863] - Suri Roowi, William Mullen, Christine A Edwards, Alan Crozier. Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans.
Molecular nutrition & food research.
2009 May; 53 Suppl 1(?):S68-75. doi:
10.1002/mnfr.200800287. [PMID: 19415668] - Laure Poquet, Michael N Clifford, Gary Williamson. Investigation of the metabolic fate of dihydrocaffeic acid.
Biochemical pharmacology.
2008 Mar; 75(5):1218-29. doi:
10.1016/j.bcp.2007.11.009. [PMID: 18154874] - David Jirovský, Pavel Kosina, Miroslava Myslínová, Jakub Stýskala, Jitka Ulrichová, Vilím Simánek. HPLC analysis of rosmarinic acid in feed enriched with aerial parts of Prunella vulgaris and its metabolites in pig plasma using dual-channel coulometric detection.
Journal of agricultural and food chemistry.
2007 Sep; 55(19):7631-7. doi:
10.1021/jf070883e. [PMID: 17708641] - José Angel Gómez-Ruiz, David S Leake, Jennifer M Ames. In vitro antioxidant activity of coffee compounds and their metabolites.
Journal of agricultural and food chemistry.
2007 Aug; 55(17):6962-9. doi:
10.1021/jf0710985. [PMID: 17655324] - E Azzini, R Bugianesi, F Romano, D Di Venere, S Miccadei, A Durazzo, M S Foddai, G Catasta, V Linsalata, G Maiani. Absorption and metabolism of bioactive molecules after oral consumption of cooked edible heads of Cynara scolymus L. (cultivar Violetto di Provenza) in human subjects: a pilot study.
The British journal of nutrition.
2007 May; 97(5):963-9. doi:
10.1017/s0007114507617218. [PMID: 17408528] - John J Beck, Jong H Kim, Bruce C Campbell, Shen-Chieh Chou. Fungicidal activities of dihydroferulic acid alkyl ester analogues.
Journal of natural products.
2007 May; 70(5):779-82. doi:
10.1021/np0606345. [PMID: 17469871] - S M Wittemer, M Ploch, T Windeck, S C Müller, B Drewelow, H Derendorf, M Veit. Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2005 Jan; 12(1-2):28-38. doi:
10.1016/j.phymed.2003.11.002. [PMID: 15693705] - A R Rechner, J P Spencer, G Kuhnle, U Hahn, C A Rice-Evans. Novel biomarkers of the metabolism of caffeic acid derivatives in vivo.
Free radical biology & medicine.
2001 Jun; 30(11):1213-22. doi:
10.1016/s0891-5849(01)00506-8. [PMID: 11368919]
