13-(3-Pentyloxiran-2-yl)trideca-2,4,6-trienoic acid (BioDeep_00000181464)
human metabolite blood metabolite
代谢物信息卡片
化学式: C20H32O3 (320.23513219999995)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 75%
分子结构信息
SMILES: CCCCCC1OC1CCCCCCC=CC=CC=CC(O)=O
InChI: InChI=1S/C20H32O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h5,7,9,11,14,17-19H,2-4,6,8,10,12-13,15-16H2,1H3,(H,21,22)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Martina Decker, Magdalena Adamska, Annette Cronin, Francesca Di Giallonardo, Julia Burgener, Anne Marowsky, John R Falck, Christophe Morisseau, Bruce D Hammock, Artiom Gruzdev, Darryl C Zeldin, Michael Arand. EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides.
Journal of lipid research.
2012 Oct; 53(10):2038-2045. doi:
10.1194/jlr.m024448. [PMID: 22798687] - Penny Zhu, Brian Peck, Hermes Licea-Perez, James F Callahan, Catherine Booth-Genthe. Development of a semi-automated LC/MS/MS method for the simultaneous quantitation of 14,15-epoxyeicosatrienoic acid, 14,15-dihydroxyeicosatrienoic acid, leukotoxin and leukotoxin diol in human plasma as biomarkers of soluble epoxide hydrolase activity in vivo.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Sep; 879(25):2487-93. doi:
10.1016/j.jchromb.2011.06.042. [PMID: 21798825] - M Revermann, A Mieth, L Popescu, A Paulke, M Wurglics, M Pellowska, A S Fischer, R Steri, T J Maier, R T Schermuly, G Geisslinger, M Schubert-Zsilavecz, R P Brandes, D Steinhilber. A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm.
British journal of pharmacology.
2011 Aug; 163(8):1721-32. doi:
10.1111/j.1476-5381.2011.01321.x. [PMID: 21410457] - Po-Chang Chiang, Yingqing Ran, Kang-Jye Chou, Yong Cui, Harvey Wong. Investigation of utilization of nanosuspension formulation to enhance exposure of 1,3-dicyclohexylurea in rats: Preparation for PK/PD study via subcutaneous route of nanosuspension drug delivery.
Nanoscale research letters.
2011 Jun; 6(1):413. doi:
10.1186/1556-276x-6-413. [PMID: 21711942] - Cui Yang, Yiu-Wa Kwan, Alice Lai-Shan Au, Christina Chui-Wa Poon, Qian Zhang, Shun-Wan Chan, Simon Ming-Yuen Lee, George Pak-Heng Leung. 14,15-Epoxyeicosatrienoic acid induces vasorelaxation through the prostaglandin EP(2) receptors in rat mesenteric artery.
Prostaglandins & other lipid mediators.
2010 Sep; 93(1-2):44-51. doi:
10.1016/j.prostaglandins.2010.06.004. [PMID: 20601071] - Beshay N M Zordoky, Mona E Aboutabl, Ayman O S El-Kadi. Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Nov; 36(11):2277-86. doi:
10.1124/dmd.108.023077. [PMID: 18725507] - Julia Kirchheiner, Ingolf Meineke, Uwe Fuhr, Cristina Rodríguez-Antona, Elena Lebedeva, Jürgen Brockmöller. Impact of genetic polymorphisms in CYP2C8 and rosiglitazone intake on the urinary excretion of dihydroxyeicosatrienoic acids.
Pharmacogenomics.
2008 Mar; 9(3):277-88. doi:
10.2217/14622416.9.3.277. [PMID: 18303964] - Walter Krugluger, Karl Moser, Claudia Moser, Katharina Laciak, Joerg Hugeneck. Enhancement of in vitro hair shaft elongation in follicles stored in buffers that prevent follicle cell apoptosis.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].
2004 Jan; 30(1):1-5; discussion 5. doi:
10.1111/j.1524-4725.2004.30010.x. [PMID: 14692918] - Dan Wang, Lillian J Borrego-Conde, John R Falck, Kamalesh K Sharma, Christopher S Wilcox, Jason G Umans. Contributions of nitric oxide, EDHF, and EETs to endothelium-dependent relaxation in renal afferent arterioles.
Kidney international.
2003 Jun; 63(6):2187-93. doi:
10.1046/j.1523-1755.2003.00036.x. [PMID: 12753306] - Xiang Fang, Neal L Weintraub, Arthur A Spector. Differences in positional esterification of 14,15-epoxyeicosatrienoic acid in phosphatidylcholine of porcine coronary artery endothelial and smooth muscle cells.
Prostaglandins & other lipid mediators.
2003 Apr; 71(1-2):33-42. doi:
10.1016/s0090-6980(03)00002-9. [PMID: 12749592]