1,5,6-Trihydroxyhexane-2,3-dione (BioDeep_00000181461)
human metabolite blood metabolite
代谢物信息卡片
1,5,6-Trihydroxyhexane-2,3-dione
化学式: C6H10O5 (162.052821)
中文名称:
谱图信息:
最多检出来源 Mus musculus(blood) 55.22%
分子结构信息
SMILES: C(C(CO)O)C(=O)C(=O)CO
InChI: InChI=1S/C6H10O5/c7-2-4(9)1-5(10)6(11)3-8/h4,7-9H,1-3H2
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- María del Carmen Hurtado-Sánchez, Anunciación Espinosa-Mansilla, María Isabel Rodríguez-Cáceres, Elisabet Martín-Tornero, Isabel Durán-Merás. Development of a method for the determination of advanced glycation end products precursors by liquid chromatography and its application in human urine samples.
Journal of separation science.
2012 Oct; 35(19):2575-84. doi:
10.1002/jssc.201200255. [PMID: 22887755] - Masanori Katakura, Michio Hashimoto, Yoko Tanabe, Osamu Shido. Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney.
Medical gas research.
2012 Jul; 2(1):18. doi:
10.1186/2045-9912-2-18. [PMID: 22776773] - Stefan Mittelmaier, Toshimitsu Niwa, Monika Pischetsrieder. Chemical and physiological relevance of glucose degradation products in peritoneal dialysis.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.
2012 Jan; 22(1):181-5. doi:
10.1053/j.jrn.2011.10.014. [PMID: 22200439] - Caatje Y le Poole, Frans J van Ittersum, Rob M Valentijn, Tom Teerlink, Bengt Lindholm, Piet M Ter Wee, Casper G Schalkwijk. "NEPP" peritoneal dialysis regimen has beneficial effects on plasma CEL and 3-DG, but not pentosidine, CML, and MGO.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2012 Jan; 32(1):45-54. doi:
10.3747/pdi.2010.00101. [PMID: 21632443] - Bruce A Perkins, Naila Rabbani, Andrew Weston, Linda H Ficociello, Antonysunil Adaikalakoteswari, Monika Niewczas, James Warram, Andrzej S Krolewski, Paul Thornalley. Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes.
PloS one.
2012; 7(4):e35655. doi:
10.1371/journal.pone.0035655. [PMID: 22558190] - Gilberto Baroni, Adriana Schuinski, Thyago P de Moraes, Fernando Meyer, Roberto Pecoits-Filho. Inflammation and the peritoneal membrane: causes and impact on structure and function during peritoneal dialysis.
Mediators of inflammation.
2012; 2012(?):912595. doi:
10.1155/2012/912595. [PMID: 22547910] - Jessica N Lange, Kyle D Wood, John Knight, Dean G Assimos, Ross P Holmes. Glyoxal formation and its role in endogenous oxalate synthesis.
Advances in urology.
2012; 2012(?):819202. doi:
10.1155/2012/819202. [PMID: 22567004] - Lian Engelen, Søren S Lund, Isabel Ferreira, Lise Tarnow, Hans-Henrik Parving, Jørgen Gram, Kaj Winther, Oluf Pedersen, Tom Teerlink, Rob Barto, Coen D A Stehouwer, Allan A Vaag, Casper G Schalkwijk. Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes.
European journal of endocrinology.
2011 Mar; 164(3):371-9. doi:
10.1530/eje-10-0851. [PMID: 21205874] - Anna Rita Aguirre, Hugo Abensur. Protective measures against ultrafiltration failure in peritoneal dialysis patients.
Clinics (Sao Paulo, Brazil).
2011; 66(12):2151-7. doi:
10.1590/s1807-59322011001200023. [PMID: 22189743] - Fatemeh Moheimani, Joanne T M Tan, Bronwyn E Brown, Alison K Heather, David M van Reyk, Michael J Davies. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins.
Experimental diabetes research.
2011; 2011(?):851280. doi:
10.1155/2011/851280. [PMID: 21904540] - Claudia Luevano-Contreras, Karen Chapman-Novakofski. Dietary advanced glycation end products and aging.
Nutrients.
2010 12; 2(12):1247-65. doi:
10.3390/nu2121247. [PMID: 22254007] - Cimen Karasu. Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment.
The open cardiovascular medicine journal.
2010 Nov; 4(?):240-56. doi:
10.2174/1874192401004010240. [PMID: 21270942] - Zohara Sternberg, Cassandra Hennies, Daniel Sternberg, Ping Wang, Peter Kinkel, David Hojnacki, Bianca Weinstock-Guttmann, Frederick Munschauer. Diagnostic potential of plasma carboxymethyllysine and carboxyethyllysine in multiple sclerosis.
Journal of neuroinflammation.
2010 Oct; 7(?):72. doi:
10.1186/1742-2094-7-72. [PMID: 21034482] - Susumu Ogawa, Keisuke Nakayama, Masaaki Nakayama, Takefumi Mori, Masato Matsushima, Masashi Okamura, Miho Senda, Kazuhiro Nako, Toshio Miyata, Sadayoshi Ito. Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure.
Hypertension (Dallas, Tex. : 1979).
2010 Sep; 56(3):471-6. doi:
10.1161/hypertensionaha.110.156786. [PMID: 20644005] - Anna Bryland, Marcus Broman, Martin Erixon, Bengt Klarin, Torbjörn Lindén, Hans Friberg, Anders Wieslander, Per Kjellstrand, Claudio Ronco, Ola Carlsson, Gabriela Godaly. Infusion fluids contain harmful glucose degradation products.
Intensive care medicine.
2010 Jul; 36(7):1213-20. doi:
10.1007/s00134-010-1873-x. [PMID: 20397009] - Naila Rabbani, Madhu Varma Chittari, Charles W Bodmer, Daniel Zehnder, Antonio Ceriello, Paul J Thornalley. Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin.
Diabetes.
2010 Apr; 59(4):1038-45. doi:
10.2337/db09-1455. [PMID: 20068133] - Ying-Ling Lai, Sae Aoyama, Ryoji Nagai, Noriyuki Miyoshi, Hiroshi Ohshima. Inhibition of L-arginine metabolizing enzymes by L-arginine-derived advanced glycation end products.
Journal of clinical biochemistry and nutrition.
2010 Mar; 46(2):177-85. doi:
10.3164/jcbn.09-104. [PMID: 20216951] - Markus A Queisser, Dachun Yao, Sven Geisler, Hans-Peter Hammes, Günter Lochnit, Erwin D Schleicher, Michael Brownlee, Klaus T Preissner. Hyperglycemia impairs proteasome function by methylglyoxal.
Diabetes.
2010 Mar; 59(3):670-8. doi:
10.2337/db08-1565. [PMID: 20009088] - Satoshi Endo, Toshiyuki Matsunaga, Anna Fujita, Kazuo Tajima, Ossama El-Kabbani, Akira Hara. Rat aldose reductase-like protein (AKR1B14) efficiently reduces the lipid peroxidation product 4-oxo-2-nonenal.
Biological & pharmaceutical bulletin.
2010; 33(11):1886-90. doi:
10.1248/bpb.33.1886. [PMID: 21048316] - Z Turk. Glycotoxines, carbonyl stress and relevance to diabetes and its complications.
Physiological research.
2010; 59(2):147-156. doi:
10.33549/physiolres.931585. [PMID: 19537931] - Shahid P Baba, Oleg A Barski, Yonis Ahmed, Timothy E O'Toole, Daniel J Conklin, Aruni Bhatnagar, Sanjay Srivastava. Reductive metabolism of AGE precursors: a metabolic route for preventing AGE accumulation in cardiovascular tissue.
Diabetes.
2009 Nov; 58(11):2486-97. doi:
10.2337/db09-0375. [PMID: 19651811] - Kota Matsuki, Naoki Tamasawa, Maki Yamashita, Jutaro Tanabe, Hiroshi Murakami, Jun Matsui, Tadaatsu Imaizumi, Kei Satoh, Toshihiro Suda. Metformin restores impaired HDL-mediated cholesterol efflux due to glycation.
Atherosclerosis.
2009 Oct; 206(2):434-8. doi:
10.1016/j.atherosclerosis.2009.03.003. [PMID: 19376519] - Martin Erixon, Anders Wieslander, Torbjörn Lindén, Ola Carlsson, Jan Ake Jönsson, Ole Simonsen, Per Kjellstrand. 3,4-dideoxyglucosone-3-ene in peritoneal dialysis fluids infused into the peritoneal cavity cannot be found in plasma.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2009 Feb; 29 Suppl 2(?):S28-31. doi:
10.1177/089686080902902s04. [PMID: 19270226] - A Ceriello, S Colagiuri. International Diabetes Federation guideline for management of postmeal glucose: a review of recommendations.
Diabetic medicine : a journal of the British Diabetic Association.
2008 Oct; 25(10):1151-6. doi:
10.1111/j.1464-5491.2008.02565.x. [PMID: 19046192] - Meng-Yan Wu, Bud-Gen Chen, Chiung Dan Chang, Mei-Han Huang, Tai-Guang Wu, Daw-Ming Chang, Yau-Jiunn Lee, Hsiang Ching Wang, Chu-I Lee, Chi-Liang Chern, Ray H Liu. A novel derivatization approach for simultaneous determination of glyoxal, methylglyoxal, and 3-deoxyglucosone in plasma by gas chromatography-mass spectrometry.
Journal of chromatography. A.
2008 Sep; 1204(1):81-6. doi:
10.1016/j.chroma.2008.07.040. [PMID: 18692194] - Martin Erixon, Anders Wieslander, Torbjörn Lindén, Ola Carlsson, Jan Ake Jönsson, Ole Simonsen, Per Kjellstrand. 3,4-DGE in peritoneal dialysis fluids cannot be found in plasma after infusion into the peritoneal cavity.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2008 May; 28(3):277-82. doi:
10.1177/089686080802800315. [PMID: 18474921] - Hiroko Odani, Jun Asami, Aiko Ishii, Kayoko Oide, Takako Sudo, Atsushi Nakamura, Noriyuki Miyata, Noboru Otsuka, Kenji Maeda, Junichi Nakagawa. Suppression of renal alpha-dicarbonyl compounds generated following ureteral obstruction by kidney-specific alpha-dicarbonyl/L-xylulose reductase.
Annals of the New York Academy of Sciences.
2008 Apr; 1126(?):320-4. doi:
10.1196/annals.1433.003. [PMID: 18079483] - Ryoji Nagai, Yukio Fujiwara, Katsumi Mera, Kazuya Yamagata, Naomi Sakashita, Motohiro Takeya. Immunochemical detection of Nepsilon-(carboxyethyl)lysine using a specific antibody.
Journal of immunological methods.
2008 Mar; 332(1-2):112-20. doi:
10.1016/j.jim.2007.12.020. [PMID: 18242632] - Keisuke Nakayama, Masaaki Nakayama, Masashi Iwabuchi, Hiroyuki Terawaki, Toshinobu Sato, Masahiro Kohno, Sadayoshi Ito. Plasma alpha-oxoaldehyde levels in diabetic and nondiabetic chronic kidney disease patients.
American journal of nephrology.
2008; 28(6):871-8. doi:
10.1159/000139653. [PMID: 18547947] - Hi Bahl Lee, Hunjoo Ha. Mechanisms of epithelial-mesenchymal transition of peritoneal mesothelial cells during peritoneal dialysis.
Journal of Korean medical science.
2007 Dec; 22(6):943-5. doi:
10.3346/jkms.2007.22.6.943. [PMID: 18162703] - V Z Lankin, A K Tikhaze, V I Kapel'ko, G S Shepel'kova, K B Shumaev, O M Panasenko, G G Konovalova, Yu N Belenkov. Mechanisms of oxidative modification of low density lipoproteins under conditions of oxidative and carbonyl stress.
Biochemistry. Biokhimiia.
2007 Oct; 72(10):1081-90. doi:
10.1134/s0006297907100069. [PMID: 18021066] - Sakurako Nakamura, Hongyan Li, Ayinuer Adijiang, Monika Pischetsrieder, Toshimitsu Niwa. Pyridoxal phosphate prevents progression of diabetic nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2007 Aug; 22(8):2165-74. doi:
10.1093/ndt/gfm166. [PMID: 17449494] - Claus Peter Schmitt, Dorothee von Heyl, Susanne Rieger, Klaus Arbeiter, Klaus Eugen Bonzel, Michel Fischbach, Joachim Misselwitz, Ann-Kathrin Pieper, Franz Schaefer. Reduced systemic advanced glycation end products in children receiving peritoneal dialysis with low glucose degradation product content.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2007 Jul; 22(7):2038-44. doi:
10.1093/ndt/gfm148. [PMID: 17420168] - François Collard, Didier Vertommen, Juliette Fortpied, Gregg Duester, Emile Van Schaftingen. Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1).
Biochimie.
2007 Mar; 89(3):369-73. doi:
10.1016/j.biochi.2006.11.005. [PMID: 17175089] - Mitsuo Tanimoto, Tomohito Gohda, Shigeru Kaneko, Shinji Hagiwara, Maki Murakoshi, Tatsuya Aoki, Kaori Yamada, Takamichi Ito, Masakazu Matsumoto, Satoshi Horikoshi, Yasuhiko Tomino. Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-A(y)/Ta mice.
Metabolism: clinical and experimental.
2007 Feb; 56(2):160-7. doi:
10.1016/j.metabol.2006.08.026. [PMID: 17224327] - Yukiko Hasuike, Rintarou Moriguchi, Reiko Hata, Kouji Miyagawa, Takahiro Kuragano, Masayo Aizawa, Shigeo Yamamoto, Kimihiko Yanase, Masaaki Izumi, Tsuyoshi Tanimoto, Takeshi Nakanishi. Role of aldose reductase in the peritoneal changes of patients undergoing peritoneal dialysis.
American journal of nephrology.
2007; 27(6):622-9. doi:
10.1159/000108358. [PMID: 17851230] - Paul J Thornalley. Endogenous alpha-oxoaldehydes and formation of protein and nucleotide advanced glycation endproducts in tissue damage.
Novartis Foundation symposium.
2007; 285(?):229-43; discussion 243. doi:
10.1002/9780470511848.ch17. [PMID: 17590998] - Jun Asami, Hiroko Odani, Aiko Ishii, Kayoko Oide, Takako Sudo, Atsushi Nakamura, Noriyuki Miyata, Noboru Otsuka, Kenji Maeda, Junichi Nakagawa. Suppression of AGE precursor formation following unilateral ureteral obstruction in mouse kidneys by transgenic expression of alpha-dicarbonyl/L-xylulose reductase.
Bioscience, biotechnology, and biochemistry.
2006 Dec; 70(12):2899-905. doi:
10.1271/bbb.60311. [PMID: 17151462] - A Watarai, E Nakashima, Y Hamada, G Watanabe, K Naruse, K Miwa, Y Kobayashi, H Kamiya, M Nakae, N Hamajima, Y Sekido, T Niwa, Y Oiso, J Nakamura. Aldose reductase gene is associated with diabetic macroangiopathy in Japanese Type 2 diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association.
2006 Aug; 23(8):894-9. doi:
10.1111/j.1464-5491.2006.01946.x. [PMID: 16911628] - Gerard T Berry, John W Baynes, Kevin J Wells-Knecht, Benjamin S Szwergold, René Santer. Elements of diabetic nephropathy in a patient with GLUT 2 deficiency.
Molecular genetics and metabolism.
2005 Dec; 86(4):473-7. doi:
10.1016/j.ymgme.2005.09.010. [PMID: 16288895] - Paul J Beisswenger, Keith S Drummond, Robert G Nelson, Scott K Howell, Benjamin S Szwergold, Michael Mauer. Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress.
Diabetes.
2005 Nov; 54(11):3274-81. doi:
10.2337/diabetes.54.11.3274. [PMID: 16249455] - Naila Ahmed, Roya Babaei-Jadidi, Scott K Howell, Paul J Thornalley, Paul J Beisswenger. Glycated and oxidized protein degradation products are indicators of fasting and postprandial hyperglycemia in diabetes.
Diabetes care.
2005 Oct; 28(10):2465-71. doi:
10.2337/diacare.28.10.2465. [PMID: 16186281] - Marina Penélope Catalan, Beatriz Santamaría, Ana Reyero, Arturo Ortiz, Jesús Egido, Alberto Ortiz. 3,4-di-deoxyglucosone-3-ene promotes leukocyte apoptosis.
Kidney international.
2005 Sep; 68(3):1303-11. doi:
10.1111/j.1523-1755.2005.00528.x. [PMID: 16105065] - C Wihler, S Schäfer, K Schmid, E K Deemer, G Münch, M Bleich, A E Busch, T Dingermann, V Somoza, J W Baynes, J Huber. Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition.
Diabetologia.
2005 Aug; 48(8):1645-53. doi:
10.1007/s00125-005-1837-9. [PMID: 16010524] - S Agalou, N Ahmed, P J Thornalley, A Dawnay. Advanced glycation end product free adducts are cleared by dialysis.
Annals of the New York Academy of Sciences.
2005 Jun; 1043(?):734-9. doi:
10.1196/annals.1333.085. [PMID: 16037300] - David R Sell, Klaus M Biemel, Oliver Reihl, Markus O Lederer, Christopher M Strauch, Vincent M Monnier. Glucosepane is a major protein cross-link of the senescent human extracellular matrix. Relationship with diabetes.
The Journal of biological chemistry.
2005 Apr; 280(13):12310-5. doi:
10.1074/jbc.m500733200. [PMID: 15677467] - Eui-Young Choi, Hyuck Moon Kwon, Chul-Woo Ahn, Geun Taek Lee, Boyoung Joung, Bum Kee Hong, Young Won Yoon, Dongsoo Kim, Ki-Hyun Byun, Tae Soo Kang, Se-Jung Yoon, Sung Woo Kwon, Sung-Ju Lee, Jong-Kwan Park, Hyun-Seung Kim. Serum levels of advanced glycation end products are associated with in-stent restenosis in diabetic patients.
Yonsei medical journal.
2005 Feb; 46(1):78-85. doi:
10.3349/ymj.2005.46.1.78. [PMID: 15744809] - Katalin Susztak, Emilio Ciccone, Peter McCue, Kumar Sharma, Erwin P Böttinger. Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy.
PLoS medicine.
2005 Feb; 2(2):e45. doi:
10.1371/journal.pmed.0020045. [PMID: 15737001] - Yoshiaki Uchida, Yoshihiro Kurano, Tomohiro Endo, Misao Aoyama, Satoru Ito. Immunochemical detection of 3-deoxyglucosone in serum.
Biochemical and biophysical research communications.
2004 Dec; 325(3):1090-8. doi:
10.1016/j.bbrc.2004.10.131. [PMID: 15541400] - Tadashi Jono, Ryoji Nagai, Xia Lin, Naila Ahmed, Paul J Thornalley, Motohiro Takeya, Seikoh Horiuchi. Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone.
Journal of biochemistry.
2004 Sep; 136(3):351-8. doi:
10.1093/jb/mvh124. [PMID: 15598892] - T R Brown, B Su, K A Brown, M A Schwartz, A M Tobia, F Kappler. Modulation of in vivo 3-deoxyglucosone levels.
Biochemical Society transactions.
2003 Dec; 31(Pt 6):1433-7. doi:
10.1042/bst0311433. [PMID: 14641082] - Paul J Thornalley. Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts.
Archives of biochemistry and biophysics.
2003 Nov; 419(1):31-40. doi:
10.1016/j.abb.2003.08.013. [PMID: 14568006] - Llinos W Morgan, Anders Wieslander, Malcolm Davies, Takashi Horiuchi, Yuji Ohta, M Janine Beavis, Kathryn J Craig, John D Williams, Nicholas Topley. Glucose degradation products (GDP) retard remesothelialization independently of D-glucose concentration.
Kidney international.
2003 Nov; 64(5):1854-66. doi:
10.1046/j.1523-1755.2003.00265.x. [PMID: 14531821] - Hitomi Kusunoki, Satoshi Miyata, Takeshi Ohara, Bing-Fen Liu, Atsuko Uriuhara, Hiroshi Kojima, Kotaro Suzuki, Hiroyuki Miyazaki, Yumiko Yamashita, Kayo Inaba, Masato Kasuga. Relation between serum 3-deoxyglucosone and development of diabetic microangiopathy.
Diabetes care.
2003 Jun; 26(6):1889-94. doi:
10.2337/diacare.26.6.1889. [PMID: 12766129] - William H Hoffman, Frank Kappler, Gregory G Passmore, Renuka Mehta. Diabetic ketoacidosis and its treatment increase plasma 3-deoxyglucosone.
Clinical biochemistry.
2003 Jun; 36(4):269-73. doi:
10.1016/s0009-9120(03)00030-4. [PMID: 12810155] - Andreas Tauer, Xiaohong Zhang, Thomas P Schaub, Thomas Zimmeck, Toshimitsu Niwa, Jutta Passlick-Deetjen, Monika Pischetsrieder. Formation of advanced glycation end products during CAPD.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2003 Mar; 41(3 Suppl 1):S57-60. doi:
10.1053/ajkd.2003.50086. [PMID: 12612954] - Naoyoshi Ishikawa, Toshio Miyata, Yasuhiko Ueda, Reiko Inagi, Yuko Izuhara, Hiroko Yuzawa, Hiroshi Onogi, Makoto Nishina, Masaomi Nangaku, Charles Van Ypersele De Strihou, Kiyoshi Kurokawa. Affinity adsorption of glucose degradation products improves the biocompatibility of conventional peritoneal dialysis fluid.
Kidney international.
2003 Jan; 63(1):331-9. doi:
10.1046/j.1523-1755.2003.00732.x. [PMID: 12472800] - Martin Zeier, Vedat Schwenger, Reinhold Deppisch, Ulrike Haug, Kai Weigel, U Bahner, Christoph Wanner, H Schneider, Thomas Henle, Eberhard Ritz. Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?.
Kidney international.
2003 Jan; 63(1):298-305. doi:
10.1046/j.1523-1755.2003.00705.x. [PMID: 12472796] - Makoto Sakai, Munetada Oimomi, Masato Kasuga. Experimental studies on the role of fructose in the development of diabetic complications.
The Kobe journal of medical sciences.
2002 Dec; 48(5-6):125-36. doi:
". [PMID: 12594356] - Mitsugu Akagawa, Takeshi Sasaki, Kyozo Suyama. Oxidative deamination of lysine residue in plasma protein of diabetic rats. Novel mechanism via the Maillard reaction.
European journal of biochemistry.
2002 Nov; 269(22):5451-8. doi:
10.1046/j.1432-1033.2002.03243.x. [PMID: 12423343] - Yukiko Hasuike, Takeshi Nakanishi, Yoshinaga Otaki, Masayoshi Nanami, Tsuyoshi Tanimoto, Naoyuki Taniguchi, Yoshihiro Takamitsu. Plasma 3-deoxyglucosone elevation in chronic renal failure is associated with increased aldose reductase in erythrocytes.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2002 Sep; 40(3):464-71. doi:
10.1053/ajkd.2002.34884. [PMID: 12200796] - Reiko Inagi, Toshio Miyata, Yasuhiko Ueda, Atsushi Yoshino, Masaomi Nangaku, Charles van Ypersele de Strihou, Kiyoshi Kurokawa. Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.
Kidney international.
2002 Aug; 62(2):679-87. doi:
10.1046/j.1523-1755.2002.00488.x. [PMID: 12110033] - Klaus M Biemel, D Alexander Friedl, Markus O Lederer. Identification and quantification of major maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound.
The Journal of biological chemistry.
2002 Jul; 277(28):24907-15. doi:
10.1074/jbc.m202681200. [PMID: 11978796] - Cristina Miki Hayashi, Ryoji Nagai, Kiminori Miyazaki, Fumitaka Hayase, Tomohiro Araki, Tomomichi Ono, Seikoh Horiuchi. Conversion of Amadori products of the Maillard reaction to N(epsilon)-(carboxymethyl)lysine by short-term heating: possible detection of artifacts by immunohistochemistry.
Laboratory investigation; a journal of technical methods and pathology.
2002 Jun; 82(6):795-808. doi:
10.1097/01.lab.0000018826.59648.07. [PMID: 12065691] - Naila Ahmed, Paul J Thornalley. Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence.
The Biochemical journal.
2002 May; 364(Pt 1):15-24. doi:
10.1042/bj3640015. [PMID: 11988071] - M Takeuchi, Y Yanase, N Matsuura, S Yamagishi Si, Y Kameda, R Bucala, Z Makita. Immunological detection of a novel advanced glycation end-product.
Molecular medicine (Cambridge, Mass.).
2001 Nov; 7(11):783-91. doi:
10.1007/bf03401969. [PMID: 11788793] - S Nakamura, S Miyazaki, S Sakai, T Morita, Y Hirasawa, T Niwa. Localization of imidazolone in the peritoneum of capd patients: a factor for a loss of ultrafiltration.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2001 Oct; 38(4 Suppl 1):S107-10. doi:
10.1053/ajkd.2001.27415. [PMID: 11576933] - S Mandl-Weber, B Haslinger, C G Schalkwijk, T Sitter. Early glycated albumin, but not advanced glycated albumin, methylglyoxal, or 3-deoxyglucosone increases the expression of PAI-1 in human peritoneal mesothelial cells.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2001 Sep; 21(5):487-94. doi:
10.1177/089686080102100510. [PMID: 11757833] - T Niwa. Dialysis-related amyloidosis: pathogenesis focusing on AGE modification.
Seminars in dialysis.
2001 Mar; 14(2):123-6. doi:
10.1046/j.1525-139x.2001.00031.x. [PMID: 11264780] - T Niwa, S Tsukushi. 3-deoxyglucosone and AGEs in uremic complications: inactivation of glutathione peroxidase by 3-deoxyglucosone.
Kidney international. Supplement.
2001 Feb; 78(?):S37-41. doi:
10.1046/j.1523-1755.2001.59780037.x. [PMID: 11168980] - A Sakai, M Nakayama, M Numata, S Takesawa, M Nakamoto. Sodium sulfite and N-acetylcysteine: new additives to dialysate for inhibiting formation of glucose degradation products and advanced glycation end-products.
Advances in peritoneal dialysis. Conference on Peritoneal Dialysis.
2001; 17(?):66-70. doi:
NULL. [PMID: 11510300] - F Kappler, M L Schwartz, B Su, A M Tobia, T Brown. DYN 12, a small molecule inhibitor of the enzyme amadorase, lowers plasma 3-deoxyglucosone levels in diabetic rats.
Diabetes technology & therapeutics.
2001; 3(4):609-16. doi:
10.1089/15209150152811234. [PMID: 11911173]