Ramipril (BioDeep_00000018022)

   

human metabolite blood metabolite


代谢物信息卡片


(2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid

化学式: C23H32N2O5 (416.2311102)
中文名称: 雷米普利
谱图信息: 最多检出来源 Homo sapiens(blood) 49.12%

分子结构信息

SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O
InChI: InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1

描述信息

Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular events.
C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

29 个代谢物同义名

(2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid; (2S-(1(R*(r*)),2a,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid; (2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylate; (2S-(1(R*(r*)),2α,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid; (2S-(1(R*(r*)),2α,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylate; (2S-(1(R*(r*)),2a,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylate; (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid; Aventis pharma brand OF ramipril; AstraZeneca brand OF ramipril; Almirall brand OF ramipril; Monarch brand OF ramipril; Aventis brand OF ramipril; Hoechst brand OF ramipril; Promed brand OF ramipril; Astra brand OF ramipril; Ramiprilum; Ramipril; Triatec; Cardace; Tritace; HOE-498; HOE 498; Carasel; Vesdil; Zabien; Acovil; Ramace; Altace; Delix



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sumera Qasim, Yusra Habib Khan, Ambreen Malik Uttra, Nasser Hadal Alotaibi, Abdullah Salah Alanazi, Abdulaziz I Alzarea, Ahmed D Alatawi, Tauqeer Hussain Mallhi. Appraisal of anti-inflammatory and immunomodulatory potential of ramipril against Freund's adjuvant-provoked arthritic rat model. Inflammopharmacology. 2023 Dec; 31(6):3115-3125. doi: 10.1007/s10787-023-01306-w. [PMID: 37543980]
  • Md Sayeed Akhtar, Md Quamrul Hassan, Obaid Afzal, Abdulmalik S A Altamimi, Mohd Zaheen Hassan, Arun Kumar, Asif Ansari Shaik Mohammad, Fauzia Tabassum. Comparative efficacy of levosimendan, ramipril, and sacubitril/valsartan in isoproterenol induced experimental heart failure: a hemodynamic and molecular approach. Current molecular pharmacology. 2022 Sep; ?(?):. doi: 10.2174/1874467215666220919104526. [PMID: 36121084]
  • Solène E Boitard, Mathilde Keck, Robin Deloux, Pierre-Emmanuel Girault-Sotias, Yannick Marc, Nadia De Mota, Delphine Compere, Onnik Agbulut, Fabrice Balavoine, Catherine Llorens-Cortes. QGC606: A Best-in-Class Orally Active Centrally Acting Aminopeptidase A Inhibitor Prodrug for Treating Heart Failure Following Myocardial Infarction. The Canadian journal of cardiology. 2022 06; 38(6):815-827. doi: 10.1016/j.cjca.2022.01.019. [PMID: 35091008]
  • Paris J Baptiste, Angel Y S Wong, Anna Schultze, Marianne Cunnington, Johannes F E Mann, Catherine Clase, Clémence Leyrat, Laurie A Tomlinson, Kevin Wing. Effects of ACE inhibitors and angiotensin receptor blockers: protocol for a UK cohort study using routinely collected electronic health records with validation against the ONTARGET trial. BMJ open. 2022 03; 12(3):e051907. doi: 10.1136/bmjopen-2021-051907. [PMID: 35260450]
  • Maryana I Prokosa. INDICATORS OF ENDOTHELIAL DYSFUNCTION, MARKERS OF INFLAMMATION AND LIPID METABOLISM IN PATIENTS WITH HYPERTENSION WITH THE ADMINISTRATION OF QUERCETIN. Wiadomosci lekarskie (Warsaw, Poland : 1960). 2022; 75(7):1653-1657. doi: 10.36740/wlek202207107. [PMID: 35962675]
  • Robert Hermann, Kristina Gundlach, Dan Seiler. Mechanistic Considerations About an Unexpected Ramipril Drug-Drug Interaction in the Development of a Triple Fixed-Dose Combination Product Containing Ramipril, Amlodipine, and Atorvastatin. Clinical pharmacology in drug development. 2021 11; 10(11):1307-1315. doi: 10.1002/cpdd.930. [PMID: 33773093]
  • Ade Meidian Ambari, Budhi Setianto, Anwar Santoso, Basuni Radi, Bambang Dwiputra, Eliana Susilowati, Fadilla Tulrahmi, Annemiek Wind, Maarten Jan Maria Cramer, Pieter Doevendans. Randomised controlled trial into the role of ramipril in fibrosis reduction in rheumatic heart disease: the RamiRHeD trial protocol. BMJ open. 2021 09; 11(9):e048016. doi: 10.1136/bmjopen-2020-048016. [PMID: 34518254]
  • Ozge Petek Erpolat, Ertugrul Senturk, Sanem Saribas, Burak Pasinlioglu, Ozlem Gulbahar, Serhan Tuncer, Volkan Demircan, Serap Catli Dinc, Omer Polat, Cigdem Elmas. Angiotensin-Converting Enzyme Inhibitor Reduces Radiation-Induced Periprosthetic Capsular Fibrosis. The Journal of surgical research. 2021 07; 263(?):167-175. doi: 10.1016/j.jss.2021.01.033. [PMID: 33667872]
  • Melanie McGinlay, Sam Straw, Jacob Jagger, Bako Nouri, John Gierula, Klaus K Witte. Impact of the COVID-19 pandemic on the management of chronic heart failure. Reviews in cardiovascular medicine. 2021 06; 22(2):271-276. doi: 10.31083/j.rcm2202034. [PMID: 34258895]
  • Michał Kuzemczak, Charalampos Kavvouras, Mohammad Alkhalil, Mark Osten. ACE inhibitor-related angioedema in a COVID-19 patient-a plausible contribution of the viral infection?. European journal of clinical pharmacology. 2021 Jun; 77(6):933-934. doi: 10.1007/s00228-020-03082-w. [PMID: 33392667]
  • Ander Vergara, Conxita Jacobs-Cachá, Mireia Molina-Van den Bosch, Pamela Domínguez-Báez, Begoña Benito, Clara García-Carro, Daniel Serón, María José Soler. Effect of ramipril on kidney, lung and heart ACE2 in a diabetic mice model. Molecular and cellular endocrinology. 2021 06; 529(?):111263. doi: 10.1016/j.mce.2021.111263. [PMID: 33811970]
  • Piero Ruggenenti, Manuel Alfredo Podestà, Matias Trillini, Annalisa Perna, Tobia Peracchi, Nadia Rubis, Davide Villa, Davide Martinetti, Monica Cortinovis, Patrizia Ondei, Carmela Giuseppina Condemi, Carlo Maria Guastoni, Agnese Meterangelis, Antonio Granata, Emanuele Mambelli, Sonia Pasquali, Simonetta Genovesi, Federico Pieruzzi, Silvio Volmer Bertoli, Goffredo Del Rosso, Maurizio Garozzo, Angelo Rigotti, Claudio Pozzi, Salvatore David, Giuseppe Daidone, Giulio Mingardi, Giovanni Mosconi, Andrea Galfré, Giorgio Romei Longhena, Alfonso Pacitti, Antonello Pani, Jorge Hidalgo Godoy, Hans-Joachim Anders, Giuseppe Remuzzi. Ramipril and Cardiovascular Outcomes in Patients on Maintenance Hemodialysis: The ARCADIA Multicenter Randomized Controlled Trial. Clinical journal of the American Society of Nephrology : CJASN. 2021 04; 16(4):575-587. doi: 10.2215/cjn.12940820. [PMID: 33782036]
  • Shouq Alkhudhayri, Rania Sajini, Bashayer Alharbi, Jumana Qabbani, Yosra Al-Hindi, Arwa Fairaq, Amal Yousef. Investigating the beneficial effect of aliskiren in attenuating neuropathic pain in diabetic Sprague-Dawley rats. Endocrinology, diabetes & metabolism. 2021 04; 4(2):e00209. doi: 10.1002/edm2.209. [PMID: 33855212]
  • Veeral Ajmera, Wesley K Thompson, Davey M Smith, Atul Malhotra, Ravindra L Mehta, Vaishal Tolia, Jeffrey Yin, Krishna Sriram, Paul A Insel, Summer Collier, Lisa Richards, Rohit Loomba. RAMIC: Design of a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of ramipril in patients with COVID-19. Contemporary clinical trials. 2021 04; 103(?):106330. doi: 10.1016/j.cct.2021.106330. [PMID: 33631357]
  • Sri Nagarjun Batchu, Harmandeep Kaur, Veera Ganesh Yerra, Suzanne L Advani, M Golam Kabir, Youan Liu, Thomas Klein, Andrew Advani. Lung and Kidney ACE2 and TMPRSS2 in Renin-Angiotensin System Blocker-Treated Comorbid Diabetic Mice Mimicking Host Factors That Have Been Linked to Severe COVID-19. Diabetes. 2021 03; 70(3):759-771. doi: 10.2337/db20-0765. [PMID: 33310740]
  • Adeolu Alex Adedapo, Ehizogie Ruth Osaretin, Olufunke Olubunmi Falayi, Ademola Adetokunbo Oyagbemi, Blessing Seun Ogunpolu, Temidayo Olutayo Omobowale, Oluwafemi Omoniyi Oguntibeju, Momoh Audu Yakubu. Ramipril blunts glycerol-induced acute renal failure in rats through its antiapoptosis, anti-inflammatory, antioxidant, and renin-inhibiting properties. Journal of basic and clinical physiology and pharmacology. 2020 Nov; 32(3):225-235. doi: 10.1515/jbcpp-2020-0032. [PMID: 33155993]
  • Yueying Wang, Gary Tse, Guangping Li, Gregory Y H Lip, Tong Liu. ACE Inhibitors and Angiotensin II Receptor Blockers May Have Different Impact on Prognosis of COVID-19. Journal of the American College of Cardiology. 2020 10; 76(17):2041. doi: 10.1016/j.jacc.2020.07.068. [PMID: 33092742]
  • Gan Mi Wang, Liang Jin Li, Wen Lu Tang, James M Wright. Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension. The Cochrane database of systematic reviews. 2020 10; 10(?):CD012569. doi: 10.1002/14651858.cd012569.pub2. [PMID: 33089502]
  • Sahil Bagai, Kunal Raj Gandhi, Gagandeep Chhabra, Rahul Grover, Dinesh Khullar. A Forgotten Cause of Thrombocytopenia in Post Renal Transplant Setting. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. 2020 Sep; 31(5):1152-1153. doi: 10.4103/1319-2442.301188. [PMID: 33229786]
  • Zeng Guo, Marko Poglitsch, Diane Cowley, Oliver Domenig, Brett C McWhinney, Jacobus P J Ungerer, Martin Wolley, Michael Stowasser. Effects of Ramipril on the Aldosterone/Renin Ratio and the Aldosterone/Angiotensin II Ratio in Patients With Primary Aldosteronism. Hypertension (Dallas, Tex. : 1979). 2020 08; 76(2):488-496. doi: 10.1161/hypertensionaha.120.14871. [PMID: 32507039]
  • Miriana d'Alessandro, Laura Bergantini, Anna Perrone, Paolo Cameli, Matteo Cameli, Antje Prasse, Dario Plataroti, Piersante Sestini, Elena Bargagli. Serial investigation of Angiotensin-Converting Enzyme in sarcoidosis patients treated with Angiotensin-Converting Enzyme Inhibitor. European journal of internal medicine. 2020 08; 78(?):58-62. doi: 10.1016/j.ejim.2020.04.006. [PMID: 32307232]
  • Manga Motrapu, Monika Katarzyna Świderska, Irene Mesas, Julian Aurelio Marschner, Yutian Lei, Laura Martinez Valenzuela, Jia Fu, Kyung Lee, Maria Lucia Angelotti, Giulia Antonelli, Paola Romagnani, Hans-Joachim Anders, Lidia Anguiano. Drug Testing for Residual Progression of Diabetic Kidney Disease in Mice Beyond Therapy with Metformin, Ramipril, and Empagliflozin. Journal of the American Society of Nephrology : JASN. 2020 08; 31(8):1729-1745. doi: 10.1681/asn.2019070703. [PMID: 32576600]
  • Inès Dufour, Quitterie Venot, Selda Aydin, Nathalie Demoulin, Guillaume Canaud, Johann Morelle. mTORC Pathway Activation and Effect of Sirolimus on Native Kidney Antiphospholipid Syndrome Nephropathy: A Case Report. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2020 08; 76(2):288-291. doi: 10.1053/j.ajkd.2019.08.032. [PMID: 31810732]
  • Ignacio J Amat-Santos, Sandra Santos-Martinez, Diego López-Otero, Luis Nombela-Franco, Enrique Gutiérrez-Ibanes, Raquel Del Valle, Erika Muñoz-García, Víctor A Jiménez-Diaz, Ander Regueiro, Rocío González-Ferreiro, Tomás Benito, Xoan Carlos Sanmartin-Pena, Pablo Catalá, Tania Rodríguez-Gabella, Jose Raúl Delgado-Arana, Manuel Carrasco-Moraleja, Borja Ibañez, J Alberto San Román. Ramipril in High-Risk Patients With COVID-19. Journal of the American College of Cardiology. 2020 07; 76(3):268-276. doi: 10.1016/j.jacc.2020.05.040. [PMID: 32470515]
  • Michael J Bloch. Renin-Angiotensin System Blockade in COVID-19: Good, Bad, or Indifferent?. Journal of the American College of Cardiology. 2020 07; 76(3):277-279. doi: 10.1016/j.jacc.2020.06.003. [PMID: 32674791]
  • Oliver Gross, Burkhard Tönshoff, Lutz T Weber, Lars Pape, Kay Latta, Henry Fehrenbach, Baerbel Lange-Sperandio, Hildegard Zappel, Peter Hoyer, Hagen Staude, Sabine König, Ulrike John, Jutta Gellermann, Bernd Hoppe, Matthias Galiano, Britta Hoecker, Rasmus Ehren, Christian Lerch, Clifford E Kashtan, Markus Harden, Jan Boeckhaus, Tim Friede. A multicenter, randomized, placebo-controlled, double-blind phase 3 trial with open-arm comparison indicates safety and efficacy of nephroprotective therapy with ramipril in children with Alport's syndrome. Kidney international. 2020 06; 97(6):1275-1286. doi: 10.1016/j.kint.2019.12.015. [PMID: 32299679]
  • Michelle N Rheault, William E Smoyer. Long-term ACE inhibition in Alport syndrome: are the benefits worth the risks?. Kidney international. 2020 06; 97(6):1104-1106. doi: 10.1016/j.kint.2020.01.030. [PMID: 32444091]
  • Tzvetanka Bondeva, Katrin Schindler, Claudia Schindler, Gunter Wolf. Ramipril pretreatment worsened renal injury and survival despite a reduction in renal inflammation in experimentally induced sepsis in mice. Journal of the renin-angiotensin-aldosterone system : JRAAS. 2020 Apr; 21(2):1470320320923977. doi: 10.1177/1470320320923977. [PMID: 32419571]
  • Zuzana Vaneková, Lukáš Hubčík, José Luis Toca-Herrera, Paul Georg Furtműller, Pavel Mučaji, Milan Nagy. Analysis of Binding Interactions of Ramipril and Quercetin on Human Serum Albumin: A Novel Method in Affinity Evaluation. Molecules (Basel, Switzerland). 2020 Jan; 25(3):. doi: 10.3390/molecules25030547. [PMID: 32012739]
  • Mostafa El Mokadem, Yasser Abd El Hady, Ashraf Aziz. A Prospective Single-Blind Randomized Trial of Ramipril, Eplerenone and Their Combination in Type 2 Diabetic Nephropathy. Cardiorenal medicine. 2020; 10(6):392-401. doi: 10.1159/000508670. [PMID: 32998143]
  • Victoria Ros-Castelló, Elena Natera-Villalba, Ana Gómez-López, Arantxa Sánchez-Sánchez, Juan Luis Chico-García, Sebastian García-Madrona, Rocio Vera-Lechuga, Consuelo Matute-Lozano, Alicia de Felipe Mimbrera, Antonio Cruz-Culebras, Araceli Alonso-Canovas, Jaime Masjuan. Use of the Cardiovascular Polypill in Secondary Prevention of Cerebrovascular Disease: A Real-Life Tertiary Hospital Cohort Study of 104 Patients. Cerebrovascular diseases extra. 2020; 10(3):166-173. doi: 10.1159/000511064. [PMID: 33176324]
  • Shivam Patel, Roshan Mathew, Sanjeev Bhoi. Caution in diagnosing angioedema as anaphylaxis. BMJ case reports. 2019 Sep; 12(9):. doi: 10.1136/bcr-2019-230329. [PMID: 31488445]
  • Barbara Ruggiero, Matias Trillini, Lida Tartaglione, Silverio Rotondi, Elena Perticucci, Rocco Tripepi, Carolina Aparicio, Veruska Lecchi, Annalisa Perna, Francesco Peraro, Davide Villa, Silvia Ferrari, Antonio Cannata, Sandro Mazzaferro, Francesca Mallamaci, Carmine Zoccali, Antonio Bellasi, Mario Cozzolino, Giuseppe Remuzzi, Piero Ruggenenti, Donald E Kohan. Effects of Sevelamer Carbonate in Patients With CKD and Proteinuria: The ANSWER Randomized Trial. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2019 09; 74(3):338-350. doi: 10.1053/j.ajkd.2019.01.029. [PMID: 31027883]
  • David M Nathan, Peter H Bennett, Jill P Crandall, Sharon L Edelstein, Ronald B Goldberg, Steven E Kahn, William C Knowler, Kieren J Mather, Sunder Mudaliar, Trevor J Orchard, Marinella Temprosa, Neil H White. Does diabetes prevention translate into reduced long-term vascular complications of diabetes?. Diabetologia. 2019 08; 62(8):1319-1328. doi: 10.1007/s00125-019-4928-8. [PMID: 31270584]
  • Daniela Carmen Ababei, Veronica Bild, Alin Ciobică, Radu Marian Lefter, Răzvan Nicolae Rusu, Walther Bild. A Comparative Study on the Memory-Enhancing Actions of Oral Renin-Angiotensin System Altering Drugs in Scopolamine-Treated Mice. American journal of Alzheimer's disease and other dementias. 2019 08; 34(5):329-336. doi: 10.1177/1533317519847042. [PMID: 31106575]
  • Michael Böhm, Helmut Schumacher, Koon K Teo, Eva M Lonn, Felix Mahfoud, Johannes F E Mann, Giuseppe Mancia, Josep Redon, Roland E Schmieder, Nikolaus Marx, Karen Sliwa, Michael A Weber, Bryan Williams, Salim Yusuf. Cardiovascular outcomes and achieved blood pressure in patients with and without diabetes at high cardiovascular risk. European heart journal. 2019 07; 40(25):2032-2043. doi: 10.1093/eurheartj/ehz149. [PMID: 30919899]
  • Xiang Peng, Haiyan Su, Dali Liang, Jeihua Li, Wei-Jen Ting, Shih-Chieh Liao, Chih-Yang Huang. Ramipril and resveratrol co-treatment attenuates RhoA/ROCK pathway-regulated early-stage diabetic nephropathy-associated glomerulosclerosis in streptozotocin-induced diabetic rats. Environmental toxicology. 2019 Jul; 34(7):861-868. doi: 10.1002/tox.22758. [PMID: 31062909]
  • Margarita Semis, Gabriel B Gugiu, Ellen A Bernstein, Kenneth E Bernstein, Markus Kalkum. The Plethora of Angiotensin-Converting Enzyme-Processed Peptides in Mouse Plasma. Analytical chemistry. 2019 05; 91(10):6440-6453. doi: 10.1021/acs.analchem.8b03828. [PMID: 31021607]
  • Kawa Dizaye, Rojgar H Ali. Effects of neprilysin-renin inhibition in comparison with neprilysin-angiotensin inhibition on the neurohumoral changes in rats with heart failure. BMC pharmacology & toxicology. 2019 05; 20(1):23. doi: 10.1186/s40360-019-0304-z. [PMID: 31053170]
  • Wei Ren, Chen Zhao, Yan Wang, Yuan Fang, Zhenzhen Huang, Wei Chen, Lihua Wang, Wen Hu, Ke Wang, Lijun Ni. Ramipril can alleviate the accumulation of renal mesangial matrix in rats with diabetic nephropathy by inhibiting insulin-like growth factor-1. Acta cirurgica brasileira. 2019 02; 34(1):e20190010000007. doi: 10.1590/s0102-865020190010000007. [PMID: 30785508]
  • Sandor Koszegi, Agnes Molnar, Lilla Lenart, Judit Hodrea, Dora Bianka Balogh, Tamas Lakat, Edgar Szkibinszkij, Adam Hosszu, Nadja Sparding, Federica Genovese, Laszlo Wagner, Adam Vannay, Attila J Szabo, Andrea Fekete. RAAS inhibitors directly reduce diabetes-induced renal fibrosis via growth factor inhibition. The Journal of physiology. 2019 01; 597(1):193-209. doi: 10.1113/jp277002. [PMID: 30324679]
  • Ewa Klara Stuermer, Manuela Besser, Nils Terberger, Hagen Sjard Bachmann, Anna-Lena Severing. Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitro. Skin pharmacology and physiology. 2019; 32(3):162-172. doi: 10.1159/000499433. [PMID: 31018213]
  • Bhargav Patel, Arvind G Jangid, B N Suhagia, Nirmal Desai. Challenges in Simultaneous Determination of Hydrochlorothiazide and Ramipril in Human Plasma: Application to a Bioequivalence Study. Journal of chromatographic science. 2018 Nov; 56(10):867-878. doi: 10.1093/chromsci/bmy055. [PMID: 29897424]
  • Marc Augustin, Georgios Schoretsanitis, Gerhard Gründer, Ekkehard Haen, Michael Paulzen. How to Treat Hypertension in Venlafaxine-Medicated Patients-Pharmacokinetic Considerations in Prescribing Amlodipine and Ramipril. Journal of clinical psychopharmacology. 2018 Oct; 38(5):498-501. doi: 10.1097/jcp.0000000000000929. [PMID: 30102628]
  • Stephen P Juraschek, Lawrence J Appel, Edgar R Miller, Kenneth J Mukamal, Lewis A Lipsitz. Hypertension Treatment Effects on Orthostatic Hypotension and Its Relationship With Cardiovascular Disease. Hypertension (Dallas, Tex. : 1979). 2018 10; 72(4):986-993. doi: 10.1161/hypertensionaha.118.11337. [PMID: 30354704]
  • Michael Böhm, Helmut Schumacher, Koon K Teo, Eva Lonn, Felix Mahfoud, Johannes F E Mann, Giuseppe Mancia, Josep Redon, Roland Schmieder, Michael Weber, Karen Sliwa, Bryan Williams, Salim Yusuf. Achieved diastolic blood pressure and pulse pressure at target systolic blood pressure (120-140 mmHg) and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials. European heart journal. 2018 09; 39(33):3105-3114. doi: 10.1093/eurheartj/ehy287. [PMID: 29873709]
  • Sophie M van den Belt, Hiddo J L Heerspink, Valentina Gracchi, Dick de Zeeuw, Elke Wühl, Franz Schaefer. Early Proteinuria Lowering by Angiotensin-Converting Enzyme Inhibition Predicts Renal Survival in Children with CKD. Journal of the American Society of Nephrology : JASN. 2018 08; 29(8):2225-2233. doi: 10.1681/asn.2018010036. [PMID: 29930161]
  • Marta Walczak-Gałęzewska, Monika Szulińska, Ewa Miller-Kasprzak, Danuta Pupek-Musialik, Paweł Bogdański. The effect of nebivolol and ramipril on selected biochemical parameters, arterial stiffness, and circadian profile of blood pressure in young men with primary hypertension: A 12-week prospective randomized, open-label study trial. Medicine. 2018 Jul; 97(30):e11717. doi: 10.1097/md.0000000000011717. [PMID: 30045336]
  • Nicholas A Fergusson, Tim Ramsay, Michaël Chassé, Shane W English, Greg A Knoll. The win ratio approach did not alter study conclusions and may mitigate concerns regarding unequal composite end points in kidney transplant trials. Journal of clinical epidemiology. 2018 06; 98(?):9-15. doi: 10.1016/j.jclinepi.2018.02.001. [PMID: 29428872]
  • R Kaseda, Y Tsuchida, J L Gamboa, J Zhong, L Zhang, H Yang, A Dikalova, A Bian, S Davies, A F Fogo, M F Linton, N J Brown, T A Ikizler, V Kon. Angiotensin receptor blocker vs ACE inhibitor effects on HDL functionality in patients on maintenance hemodialysis. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2018 06; 28(6):582-591. doi: 10.1016/j.numecd.2018.02.020. [PMID: 29691148]
  • A Maruschak, E Shorikov, I Timofiichuk, I Davydenko, K Slobodyan. PATHOMORPHOLOGY OF THE MYOCARDIUM, KIDNEY AND LIVER IN SPONTANEOUSLY HYPERTENSIVE RATS TREATED WITH SHORT AND LONG-TERM USE RAMIPRIL AND CANDESARTAN. Georgian medical news. 2018 Mar; ?(276):135-143. doi: NULL. [PMID: 29697397]
  • Lin Yun, Xingshun Xu, Ying Dai, Rui Xu, Guohua Li, Yucai Yao, Jiamin Li, Fei Zheng. The effects of single and combined application of ramipril and losartan on renal structure and function in hypertensive rats. Clinical and experimental hypertension (New York, N.Y. : 1993). 2018; 40(7):617-623. doi: 10.1080/10641963.2017.1416118. [PMID: 29256643]
  • Ali Sigaroudi, Martina Kinzig, Oliver Wahl, Christoph Stelzer, Michael Schroeter, Uwe Fuhr, Ulrike Holzgrabe, Fritz Sörgel. Quantification of Hydrochlorothiazide and Ramipril/Ramiprilate in Blood Serum and Cerebrospinal Fluid: A Pharmacokinetic Assessment of Central Nervous System Adverse Effects. Pharmacology. 2018; 102(3-4):133-137. doi: 10.1159/000489999. [PMID: 29982257]
  • Sidy Mohamed Seck, Dominique Doupa, Diatou Guéye Dia, ElHadji Assane Diop, Denis-Luc Ardiet, Renata Campos Nogueira, Bertrand Graz, Boucar Diouf. Clinical efficacy of African traditional medicines in hypertension: A randomized controlled trial with Combretum micranthum and Hibiscus sabdariffa. Journal of human hypertension. 2017 12; 32(1):75-81. doi: 10.1038/s41371-017-0001-6. [PMID: 29311704]
  • Micheal S Ward, Nicole B Flemming, Linda A Gallo, Amelia K Fotheringham, Domenica A McCarthy, Aowen Zhuang, Peter H Tang, Danielle J Borg, Hannah Shaw, Benjamin Harvie, David R Briskey, Llion A Roberts, Manuel R Plan, Michael P Murphy, Mark P Hodson, Josephine M Forbes. Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes. Scientific reports. 2017 11; 7(1):15190. doi: 10.1038/s41598-017-15589-x. [PMID: 29123192]
  • Murali Mohan Reddy Devalapalli, Hanumanth Srikanth Cheruvu, Thejaswi Yertha, Vijaya Bhaskar Veeravalli, Sunitha Sampathi, Savithri Shivakumar. Hansen solubility parameters for assay method optimization of simvastatin, ramipril, atenolol, hydrochlorothiazide and aspirin in human plasma using liquid chromatography with tandem mass spectrometry. Journal of separation science. 2017 Sep; 40(18):3662-3674. doi: 10.1002/jssc.201700565. [PMID: 28722356]
  • Salma Malik, Kapil Suchal, Sana Irfan Khan, Jagriti Bhatia, Kamal Kishore, Amit Kumar Dinda, Dharamvir Singh Arya. Apigenin ameliorates streptozotocin-induced diabetic nephropathy in rats via MAPK-NF-κB-TNF-α and TGF-β1-MAPK-fibronectin pathways. American journal of physiology. Renal physiology. 2017 Aug; 313(2):F414-F422. doi: 10.1152/ajprenal.00393.2016. [PMID: 28566504]
  • Miles J De Blasio, Anand Ramalingam, Anh H Cao, Darnel Prakoso, Ji-Ming Ye, Raelene Pickering, Anna M D Watson, Judy B de Haan, David M Kaye, Rebecca H Ritchie. The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy. European journal of pharmacology. 2017 Jul; 807(?):12-20. doi: 10.1016/j.ejphar.2017.04.026. [PMID: 28438648]
  • Michael Böhm, Helmut Schumacher, Koon K Teo, Eva M Lonn, Felix Mahfoud, Johannes F E Mann, Giuseppe Mancia, Josep Redon, Roland E Schmieder, Karen Sliwa, Michael A Weber, Bryan Williams, Salim Yusuf. Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials. Lancet (London, England). 2017 Jun; 389(10085):2226-2237. doi: 10.1016/s0140-6736(17)30754-7. [PMID: 28390695]
  • Izabela Zakrocka, Tomasz Kocki, Waldemar A Turski. The effect of three angiotensin-converting enzyme inhibitors on kynurenic acid production in rat kidney in vitro. Pharmacological reports : PR. 2017 Jun; 69(3):536-541. doi: NULL. [PMID: 28364692]
  • Barinder Singh, Ashish Mourya, Sangeeta Pilkhwal Sah, Anil Kumar. Protective effect of losartan and ramipril against stress induced insulin resistance and related complications: Anti-inflammatory mechanisms. European journal of pharmacology. 2017 Apr; 801(?):54-61. doi: 10.1016/j.ejphar.2017.02.050. [PMID: 28259714]
  • Catherine M Clase, Joshua Barzilay, Peggy Gao, Andrew Smyth, Roland E Schmieder, Sheldon Tobe, Koon K Teo, Salim Yusuf, Johannes F E Mann. Acute change in glomerular filtration rate with inhibition of the renin-angiotensin system does not predict subsequent renal and cardiovascular outcomes. Kidney international. 2017 03; 91(3):683-690. doi: 10.1016/j.kint.2016.09.038. [PMID: 27927602]
  • P Deska, M Nowicki. Short-term changes of serum potassium concentration induced by physical exercise in patient with arterial hypertension treated with angiotensin-converting enzyme inhibitor alone or in combination with statin. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2017 Feb; 68(1):133-138. doi: NULL. [PMID: 28456777]
  • Piero Ruggenenti, Paolo Cravedi, Antonietta Chianca, MariaRosa Caruso, Giuseppe Remuzzi. Achieving remission of proteinuria in childhood CKD. Pediatric nephrology (Berlin, Germany). 2017 02; 32(2):321-330. doi: 10.1007/s00467-016-3495-1. [PMID: 27704256]
  • Paola Cianfrone, Mariadelina Simeoni, Nicola Comi, Valentina Piraina, Roberta Talarico, Annamaria Cerantonio, Innocenza Gentile, Flora Fortunata Fabiano, Gaetano Lucisano, Daniela Foti, Elio Gulletta, Giorgio Fuiano. How to improve duration and efficiency of the antiproteinuric response to Ramipril: RamiPROT-a prospective cohort study. Journal of nephrology. 2017 Feb; 30(1):95-102. doi: 10.1007/s40620-015-0256-3. [PMID: 26707494]
  • A J Kwakernaak, L C Roksnoer, H J Lambers Heerspink, I van den Berg-Garrelds, G A Lochorn, J H van Embden Andres, M A Klijn, H Kobori, A H J Danser, G D Laverman, G J Navis. Effects of Direct Renin Blockade on Renal & Systemic Hemodynamics and on RAAS Activity, in Weight Excess and Hypertension: A Randomized Clinical Trial. PloS one. 2017; 12(1):e0169258. doi: 10.1371/journal.pone.0169258. [PMID: 28118402]
  • Louise M Burrell, Daniel Gayed, Karen Griggs, Sheila K Patel, Elena Velkoska. Adverse cardiac effects of exogenous angiotensin 1-7 in rats with subtotal nephrectomy are prevented by ACE inhibition. PloS one. 2017; 12(2):e0171975. doi: 10.1371/journal.pone.0171975. [PMID: 28192475]
  • Björn Tampe, Ulrike Steinle, Désirée Tampe, Julienne L Carstens, Peter Korsten, Elisabeth M Zeisberg, Gerhard A Müller, Raghu Kalluri, Michael Zeisberg. Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression. Kidney international. 2017 01; 91(1):157-176. doi: 10.1016/j.kint.2016.07.042. [PMID: 27692563]
  • Stephen R Spindler, Patricia L Mote, James M Flegal. Combined statin and angiotensin-converting enzyme (ACE) inhibitor treatment increases the lifespan of long-lived F1 male mice. Age (Dordrecht, Netherlands). 2016 Dec; 38(5-6):379-391. doi: 10.1007/s11357-016-9948-4. [PMID: 27590905]
  • Jie-Hua Shi, Dong-Qi Pan, Min Jiang, Ting-Ting Liu, Qi Wang. Binding interaction of ramipril with bovine serum albumin (BSA): Insights from multi-spectroscopy and molecular docking methods. Journal of photochemistry and photobiology. B, Biology. 2016 Nov; 164(?):103-111. doi: 10.1016/j.jphotobiol.2016.09.025. [PMID: 27664380]
  • Peter Raphael Franken, Ronja Woltersdorf. Risk of renal dysfunction in an elderly patient with chronic heart failure. Medizinische Monatsschrift fur Pharmazeuten. 2016 Oct; 39(10):421-6. doi: NULL. [PMID: 29979537]
  • Sadiya Khwaja, Tarique Mahmood, Hefazat H Siddiqui. Effect of ethanolic extract of Cyperus rotundus L. against isoprenaline induced cardiotoxicity. Indian journal of experimental biology. 2016 Oct; 54(10):670-675. doi: . [PMID: 30084568]
  • Erminia Donnarumma, Murtuza J Ali, Amanda M Rushing, Amy L Scarborough, Jessica M Bradley, Chelsea L Organ, Kazi N Islam, David J Polhemus, Stefano Evangelista, Giuseppe Cirino, J Stephen Jenkins, Rajan A G Patel, David J Lefer, Traci T Goodchild. Zofenopril Protects Against Myocardial Ischemia-Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability. Journal of the American Heart Association. 2016 07; 5(7):. doi: 10.1161/jaha.116.003531. [PMID: 27381758]
  • Gabor Simonyi. Benefits of Fixed Dose Combination of Ramipril/Amlodipine in Hypertensive Diabetic Patients: A Subgroup Analysis of RAMONA Trial. Chinese medical journal. 2016 May; 129(10):1224-8. doi: 10.4103/0366-6999.181959. [PMID: 27174332]
  • Greg A Knoll, Dean Fergusson, Michaël Chassé, Paul Hebert, George Wells, Lee Anne Tibbles, Darin Treleaven, David Holland, Christine White, Norman Muirhead, Marcelo Cantarovich, Michel Paquet, Bryce Kiberd, Sita Gourishankar, Jean Shapiro, Ramesh Prasad, Edward Cole, Helen Pilmore, Valerie Cronin, Debora Hogan, Tim Ramsay, John Gill. Ramipril versus placebo in kidney transplant patients with proteinuria: a multicentre, double-blind, randomised controlled trial. The lancet. Diabetes & endocrinology. 2016 Apr; 4(4):318-26. doi: 10.1016/s2213-8587(15)00368-x. [PMID: 26608067]
  • A Madro, J Kurzepa, K Celinski, M Slomka, G Czechowska, J Kurzepa, W Kazmierak, G Buszewicz, M Ciesielka, R Madro. Effects of renin-angiotensin system inhibitors on fibrosis in patients with alcoholic chronic pancreatitis. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2016 Feb; 67(1):103-10. doi: . [PMID: 27010899]
  • J M Serrano-Rodríguez, M Gómez-Díez, M Esgueva, C Castejón-Riber, A Mena-Bravo, F Priego-Capote, J M Serrano Caballero, A Muñoz. Pharmacokinetics and pharmacodynamics of ramipril and ramiprilat after intravenous and oral doses of ramipril in healthy horses. Veterinary journal (London, England : 1997). 2016 Feb; 208(?):38-43. doi: 10.1016/j.tvjl.2015.10.024. [PMID: 26639833]
  • Hasan Mahmud Reza, Nabila Tabassum, Md Abu Taher Sagor, Mohammed Riaz Hasan Chowdhury, Mahbubur Rahman, Preeti Jain, Md Ashraful Alam. Angiotensin-converting enzyme inhibitor prevents oxidative stress, inflammation, and fibrosis in carbon tetrachloride-treated rat liver. Toxicology mechanisms and methods. 2016; 26(1):46-53. doi: 10.3109/15376516.2015.1124956. [PMID: 26862777]
  • Angelo Zinellu, Salvatore Sotgia, Arduino A Mangoni, Elisabetta Sotgiu, Sara Ena, Dionigia Arru, Stefano Assaretti, Angela Baralla, Andrea E Satta, Ciriaco Carru. Effects of Ramipril and Telmisartan on Plasma Concentrations of Low Molecular Weight and Protein Thiols and Carotid Intima Media Thickness in Patients with Chronic Kidney Disease. Disease markers. 2016; 2016(?):1821596. doi: 10.1155/2016/1821596. [PMID: 27881888]
  • Indrajeetsinh Rana, Elena Velkoska, Sheila K Patel, Louise M Burrell, Fadi J Charchar. MicroRNAs mediate the cardioprotective effect of angiotensin-converting enzyme inhibition in acute kidney injury. American journal of physiology. Renal physiology. 2015 Dec; 309(11):F943-54. doi: 10.1152/ajprenal.00183.2015. [PMID: 26400542]
  • D A Mandelbrot, J Alberú, A Barama, B A Marder, H T Silva, S M Flechner, A Flynn, C Healy, H Li, M A Tortorici, S L Schulman. Effect of Ramipril on Urinary Protein Excretion in Maintenance Renal Transplant Patients Converted to Sirolimus. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2015 12; 15(12):3174-84. doi: 10.1111/ajt.13384. [PMID: 26176342]
  • Shih-Chun Hsing, Kuo-Cheng Lu, Chien-An Sun, Wu-Chien Chien, Chi-Hsiang Chung, Sen-Yeong Kao. The Association of Losartan and Ramipril Therapy With Kidney and Cardiovascular Outcomes in Patients With Chronic Kidney Disease: A Chinese Nation-Wide Cohort Study in Taiwan. Medicine. 2015 Dec; 94(48):e1999. doi: 10.1097/md.0000000000001999. [PMID: 26632888]
  • Jorge L Gamboa, Mias Pretorius, Katie C Sprinkel, Nancy J Brown, T Alp Ikizler. Angiotensin converting enzyme inhibition increases ADMA concentration in patients on maintenance hemodialysis--a randomized cross-over study. BMC nephrology. 2015 Oct; 16(?):167. doi: 10.1186/s12882-015-0162-x. [PMID: 26494370]
  • Mariam Gamal Fahmy Wahba, Basim Anwar Shehata Messiha, Ali Ahmed Abo-Saif. Ramipril and haloperidol as promising approaches in managing rheumatoid arthritis in rats. European journal of pharmacology. 2015 Oct; 765(?):307-15. doi: 10.1016/j.ejphar.2015.08.026. [PMID: 26302059]
  • Vera Bernardino, Pedro Mendes-Bastos, Ana Rodrigues, Nuno Riso. IgA vasculitis (formerly Henoch-Schönlein purpura) in an adult with systemic lupus erythematosus. BMJ case reports. 2015 Sep; 2015(?):. doi: 10.1136/bcr-2015-210121. [PMID: 26354836]
  • Ericha G Anthony, Erin Richard, Michael S Lipkowitz, Vibha Bhatnagar. Association of the ADRB2 (rs2053044) polymorphism and angiotensin-converting enzyme-inhibitor blood pressure response in the African American Study of Kidney Disease and Hypertension. Pharmacogenetics and genomics. 2015 Sep; 25(9):444-9. doi: 10.1097/fpc.0000000000000154. [PMID: 26111150]
  • Tali Cukierman-Yaffe, Craig Anderson, Koon Teo, Peggy Gao, Hertzel C Gerstein, Salim Yusuf. Dysglycemia and Cognitive Dysfunction and Ill Health in People With High CV Risk: Results From the ONTARGET/TRANSCEND Studies. The Journal of clinical endocrinology and metabolism. 2015 Jul; 100(7):2682-9. doi: 10.1210/jc.2015-1367. [PMID: 26020764]
  • Paweł Szpot, Grzegorz Buszewicz. Determination of ramipril in human plasma and its fragmentation by UPLC-Q-TOF-MS with positive electrospray ionization. Acta pharmaceutica (Zagreb, Croatia). 2015 Jun; 65(2):159-69. doi: 10.1515/acph-2015-0018. [PMID: 26011932]
  • Alan Russell, Suman Chatterjee, Michael Seed. Does this case hold the answer to one of the worse types of pain in medicine--that of loin pain haematuria syndrome (LPHS). BMJ case reports. 2015 Apr; 2015(?):. doi: 10.1136/bcr-2014-209165. [PMID: 25917070]
  • Ştefania Corina Mahu, Monica Hăncianu, Luminiţa Agoroaei, Ioana Cezara Grigoriu, Anca Monica Strugaru, Elena Butnaru. FIXED DOSE COMBINATIONS WITH SELECTIVE BETA-BLOCKERS: QUANTITATIVE DETERMINATION IN BIOLOGICAL FLUIDS. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 2015 Apr; 119(2):585-91. doi: NULL. [PMID: 26204671]
  • Jahnavi V Pathak, Ervilla E Dass. A retrospective study of the effects of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in diabetic nephropathy. Indian journal of pharmacology. 2015 Mar; 47(2):148-52. doi: 10.4103/0253-7613.153420. [PMID: 25878372]
  • Maria Nassiri, Magda Babina, Sabine Dölle, Günter Edenharter, Franziska Ruëff, Margitta Worm. Ramipril and metoprolol intake aggravate human and murine anaphylaxis: evidence for direct mast cell priming. The Journal of allergy and clinical immunology. 2015 Feb; 135(2):491-9. doi: 10.1016/j.jaci.2014.09.004. [PMID: 25441633]
  • Markus R Meyer, Aline Schütz, Hans H Maurer. Contribution of human esterases to the metabolism of selected drugs of abuse. Toxicology letters. 2015 Jan; 232(1):159-66. doi: 10.1016/j.toxlet.2014.10.026. [PMID: 25445008]
  • Matthew A Weir, Jamie L Fleet, Stephanie N Dixon, Arsh K Jain, Matthew Oliver, Ron Wald, Chris McIntyre, Amit X Garg. Angiotensin Converting Enzyme Inhibitor Dialyzability and Outcomes in Older Patients Receiving Hemodialysis. Blood purification. 2015; 40(3):232-42. doi: 10.1159/000438821. [PMID: 26382240]
  • Mariadelina Simeoni, Paola Cianfrone, Nicola Comi, Innocenza Gentile, Flora Fortunata Fabiano, Valentina Piraina, Roberta Talarico, Gaetano Lucisano, Laura Rivoli, Michele Andreucci, Laura Fuiano, Daniela Foti, Elio Gulletta, Giorgio Fuiano. [Is it feasible to improve the duration and the efficiency of Ramipril anti-proteinuric response?]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. 2015 Jan; 32(1):. doi: NULL. [PMID: 25774586]
  • Jeanne d'Arc AlBacha, Mira Khoury, Charbel Mouawad, Katia Haddad, Samar Hamoui, Albert Azar, Ziad Fajloun, Nehman Makdissy. High Incidence of ACE/PAI-1 in Association to a Spectrum of Other Polymorphic Cardiovascular Genes Involving PBMCs Proinflammatory Cytokines in Hypertensive Hypercholesterolemic Patients: Reversibility with a Combination of ACE Inhibitor and Statin. PloS one. 2015; 10(5):e0127266. doi: 10.1371/journal.pone.0127266. [PMID: 25973747]
  • Guillaume A Favre, Patricia Lebrun, Pascal Lopez, Catherine Butori, Paul Hofman, Vincent Lm Esnault, Emmanuel Van Obberghen. Constitutive activation of the renin-angiotensin system reduces visceral fat and improves glucose tolerance in mice. Journal of the renin-angiotensin-aldosterone system : JRAAS. 2014 Dec; 15(4):396-409. doi: 10.1177/1470320314537695. [PMID: 25371094]
  • Rosaline Quinlivan, Andrea Martinuzzi, Benedikt Schoser. Pharmacological and nutritional treatment for McArdle disease (Glycogen Storage Disease type V). The Cochrane database of systematic reviews. 2014 Nov; ?(11):CD003458. doi: 10.1002/14651858.cd003458.pub5. [PMID: 25391139]
  • Jatin R Patel, Trupesh M Pethani, Ashish N Vachhani, Navin R Sheth, Ashvin V Dudhrejiya. Development and validation of bioanalytical method for simultaneous estimation of ramipril and hydrochlorothiazide in human plasma using liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2014 Nov; 970(?):53-9. doi: 10.1016/j.jchromb.2014.08.023. [PMID: 25240204]