Dipyridamole (BioDeep_00000017976)

   

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol

化学式: C24H40N8O4 (504.31723600000004)
中文名称: 双嘧达莫
谱图信息: 最多检出来源 Homo sapiens(blood) 4.57%

分子结构信息

SMILES: C1CCN(CC1)c1c2c(c(nc(n2)N(CCO)CCO)N2CCCCC2)nc(n1)N(CCO)CCO
InChI: InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2

描述信息

Dipyridamole is only found in individuals that have used or taken this drug. It is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)Dipyridamole likely inhibits both adenosine deaminase and phosphodiesterase, preventing the degradation of cAMP, an inhibitor of platelet function. This elevation in cAMP blocks the release of arachidonic acid from membrane phospholipids and reduces thromboxane A2 activity. Dipyridamole also directly stimulates the release of prostacyclin, which induces adenylate cyclase activity, thereby raising the intraplatelet concentration of cAMP and further inhibiting platelet aggregation.
B - Blood and blood forming organs > B01 - Antithrombotic agents > B01A - Antithrombotic agents > B01AC - Platelet aggregation inhibitors excl. heparin
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

33 个代谢物同义名

2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol; Boehringer ingelheim brand OF dipyridamole; Berlin-chemie brand OF dipyridamole; Berlin chemie brand OF dipyridamole; Ashbourne brand OF dipyridamole; Novopharm brand OF dipyridamole; Apotex brand OF dipyridamole; Belmac brand OF dipyridamole; IPRAD brand OF dipyridamole; Apo dipyridamole; Apo-dipyridamole; Antistenocardin; Novo-dipiradol; Novo dipiradol; Cleridium 150; Dipyridamolum; dipyridamole; Dipyridamine; Dipyramidole; Dypyridamol; Dipiridamol; Cerebrovase; Dipyudamine; Dipyridamol; Persantine; Usaf ge-12; Cléridium; Persantin; Kurantil; Cardoxin; Curantil; Curantyl; Miosen



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Rita Pepponi, Roberta De Simone, Chiara De Nuccio, Sergio Visentin, Andrea Matteucci, Antonietta Bernardo, Patrizia Popoli, Antonella Ferrante. Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study. International journal of molecular sciences. 2022 Mar; 23(7):. doi: 10.3390/ijms23073456. [PMID: 35408815]
  • Fabio Urbina, Ana C Puhl, Sean Ekins. Recent advances in drug repurposing using machine learning. Current opinion in chemical biology. 2021 12; 65(?):74-84. doi: 10.1016/j.cbpa.2021.06.001. [PMID: 34274565]
  • Hanuman Prasad Sharma, Nabanita Halder, Sundararajan Baskar Singh, T Velpandian. Evaluation of the Presence and Functional Importance of Nucleoside Transporters in Lacrimal Gland for Tear Disposition of Intravenously Injected Substrate in Rabbits. Current eye research. 2021 11; 46(11):1659-1665. doi: 10.1080/02713683.2021.1925698. [PMID: 33941003]
  • Jibin Li, Nicole Spivey, Svitlana Silchenko, Isabel Gonzalez-Alvarez, Marival Bermejo, Ismael J Hidalgo. A differential equation based modelling approach to predict supersaturation and in vivo absorption from in vitro dissolution-absorption system (idas2) data. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2021 Aug; 165(?):1-12. doi: 10.1016/j.ejpb.2021.05.003. [PMID: 33971275]
  • Dinala Jialiken, Lichao Qian, Shuai Ren, Lihua Wu, Junyao Xu, Chong Zou. Combined therapy of hypertensive nephropathy with ginkgo leaf extract and dipyridamole injection and antihypertensive drugs: A systematic review and meta-analysis. Medicine. 2021 May; 100(19):e25852. doi: 10.1097/md.0000000000025852. [PMID: 34106629]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tihamer Molnar, Andrea Horvath, Zsuzsanna Szabo, Zoltan Vamos, Tamas Dóczi, Zsolt Illes. Detection of silent cerebral microcirculatory abnormalities in patients with manifest ischemic coronary disease: a perfusion brain MRI study combined with dipyridamole stress. Scandinavian cardiovascular journal : SCJ. 2021 Apr; 55(2):97-101. doi: 10.1080/14017431.2020.1821911. [PMID: 32945202]
  • Vignesh Surianarayanan, Thomas J Hoather, Samuel J Tingle, Emily R Thompson, John Hanley, Colin H Wilson. Interventions for preventing thrombosis in solid organ transplant recipients. The Cochrane database of systematic reviews. 2021 03; 3(?):CD011557. doi: 10.1002/14651858.cd011557.pub2. [PMID: 33720396]
  • Chunlong Ma, Jun Wang. Dipyridamole, chloroquine, montelukast sodium, candesartan, oxytetracycline, and atazanavir are not SARS-CoV-2 main protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 2021 02; 118(8):. doi: 10.1073/pnas.2024420118. [PMID: 33568498]
  • Zhe Li, Yuxi Lin, Yi-You Huang, Runduo Liu, Chang-Guo Zhan, Xin Wang, Hai-Bin Luo. Reply to Ma and Wang: Reliability of various in vitro activity assays on SARS-CoV-2 main protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 2021 02; 118(8):. doi: 10.1073/pnas.2024937118. [PMID: 33568500]
  • Ryan M Esquejo, Manuel Roqueta-Rivera, Wei Shao, Peter E Phelan, Uthpala Seneviratne, Christopher W Am Ende, Paul M Hershberger, Carolyn E Machamer, Peter J Espenshade, Timothy F Osborne. Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum. Cell chemical biology. 2021 02; 28(2):169-179.e7. doi: 10.1016/j.chembiol.2020.10.003. [PMID: 33096051]
  • Tracy Hampton. Autoantibodies May Drive COVID-19 Blood Clots. JAMA. 2021 02; 325(5):425. doi: 10.1001/jama.2020.25699. [PMID: 33528515]
  • Majed Malak, Emily Christie, Kevin Wen, Haimanot Wasse, Morteza Hajihosseini, Padma Kaul, Paolo Raggi. Reduced myocardial blood flow reserve in kidney transplant candidates may hamper risk stratification. Journal of nephrology. 2021 02; 34(1):197-209. doi: 10.1007/s40620-020-00736-x. [PMID: 32277424]
  • Kholoud F Aliter, Rami A Al-Horani. Potential Therapeutic Benefits of Dipyridamole in COVID-19 Patients. Current pharmaceutical design. 2021; 27(6):866-875. doi: 10.2174/1381612826666201001125604. [PMID: 33001004]
  • Christina Mallarino-Haeger, Kaleab Z Abebe, Edwin K Jackson, Ashley Zyhowski, Cynthia Klamar-Blain, Joshua C Cyktor, Diane Comer, Rhonda M Brand, Delbert G Gillespie, Kyle Holleran, John W Mellors, Ian McGowan, Sharon A Riddler, Bernard J C Macatangay. Brief Report: Dipyridamole Decreases Gut Mucosal Regulatory T-Cell Frequencies Among People With HIV on Antiretroviral Therapy. Journal of acquired immune deficiency syndromes (1999). 2020 12; 85(5):665-669. doi: 10.1097/qai.0000000000002488. [PMID: 33177477]
  • Zhe Li, Xin Li, Yi-You Huang, Yaoxing Wu, Runduo Liu, Lingli Zhou, Yuxi Lin, Deyan Wu, Lei Zhang, Hao Liu, Ximing Xu, Kunqian Yu, Yuxia Zhang, Jun Cui, Chang-Guo Zhan, Xin Wang, Hai-Bin Luo. Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs. Proceedings of the National Academy of Sciences of the United States of America. 2020 11; 117(44):27381-27387. doi: 10.1073/pnas.2010470117. [PMID: 33051297]
  • James J DiNicolantonio, Jorge Barroso-Aranda. Harnessing adenosine A2A receptors as a strategy for suppressing the lung inflammation and thrombotic complications of COVID-19: Potential of pentoxifylline and dipyridamole. Medical hypotheses. 2020 Oct; 143(?):110051. doi: 10.1016/j.mehy.2020.110051. [PMID: 32650197]
  • Chin-Yi Liao, Timothy L Tan, Yu-Der Lu, Cheng-Ta Wu, Mel S Lee, Feng-Chih Kuo. Does preoperative dipyridamole-thallium scanning reduce 90-day cardiac complications and 1-year mortality in patients with femoral neck fractures undergoing hemiarthroplasty?. Journal of orthopaedic surgery and research. 2020 Sep; 15(1):385. doi: 10.1186/s13018-020-01918-w. [PMID: 32894146]
  • Marion Mussbacher, Teresa L Krammer, Stefan Heber, Waltraud C Schrottmaier, Stephan Zeibig, Hans-Peter Holthoff, David Pereyra, Patrick Starlinger, Matthias Hackl, Alice Assinger. Impact of Anticoagulation and Sample Processing on the Quantification of Human Blood-Derived microRNA Signatures. Cells. 2020 08; 9(8):. doi: 10.3390/cells9081915. [PMID: 32824700]
  • Lukas Klumpp, Jennifer Dressman. Physiologically based pharmacokinetic model outputs depend on dissolution data and their input: Case examples glibenclamide and dipyridamole. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2020 Aug; 151(?):105380. doi: 10.1016/j.ejps.2020.105380. [PMID: 32442630]
  • Yogendra Kanthi, Jason S Knight, Yu Zuo, David J Pinsky. New (re)purpose for an old drug: purinergic modulation may extinguish the COVID-19 thromboinflammatory firestorm. JCI insight. 2020 07; 5(14):. doi: 10.1172/jci.insight.140971. [PMID: 32530438]
  • Te-I Chang, Cheng-Hsien Chen, Hui-Ling Hsieh, Chun-You Chen, Shih-Chang Hsu, Ho-Shun Cheng, Wen-Cheng Huang, Yuh-Mou Sue, Yung-Ho Hsu, Feng-Yen Lin, Chun-Ming Shih, Shing-Jong Lin, Po-Hsun Huang, Chung-Te Liu. Effects of cardiovascular medications on primary patency of hemodialysis arteriovenous fistula. Scientific reports. 2020 07; 10(1):12135. doi: 10.1038/s41598-020-69019-6. [PMID: 32699337]
  • Shumaila Afrin, Yusra Rahman, Mustafa Alhaji Isa, Shahbaz Ahmed, Mohammad Tabish. Biophysical insights into the binding characteristics of bovine serum albumin with dipyridamole and the influence of molecular interaction with β cyclodextrin. Journal of biomolecular structure & dynamics. 2020 Jul; 38(10):3046-3058. doi: 10.1080/07391102.2019.1651220. [PMID: 31366288]
  • Bernard J C Macatangay, Edwin K Jackson, Kaleab Z Abebe, Diane Comer, Joshua Cyktor, Cynthia Klamar-Blain, Luann Borowski, Delbert G Gillespie, John W Mellors, Charles R Rinaldo, Sharon A Riddler. A Randomized, Placebo-Controlled, Pilot Clinical Trial of Dipyridamole to Decrease Human Immunodeficiency Virus-Associated Chronic Inflammation. The Journal of infectious diseases. 2020 04; 221(10):1598-1606. doi: 10.1093/infdis/jiz344. [PMID: 31282542]
  • Jian Qiu, Yijun Guo, Xin Xu, Hongmei Yue, Yapei Yang. Ginkgo leaf extract and dipyridamole injection for chronic cor pulmonale: a PRISMA-compliant meta-analysis of randomized controlled trials. Bioscience reports. 2020 03; 40(3):. doi: 10.1042/bsr20200099. [PMID: 32124923]
  • Paul Billoir, Thomas Clavier, Arnaud Guilbert, Virginie Barbay, Marie Hélène Chrétien, Marielle Fresel, Caroline Abriou, Christophe Girault, Véronique Le Cam Duchez. [Theophylline adenosine dipyridamole (CTAD) and citrate evaluation to survey unfractionated heparin treatment: a delayed centrifugation validation for anti-Xa measurement?]. Annales de biologie clinique. 2020 02; 78(1):27-34. doi: 10.1684/abc.2020.1525. [PMID: 32108577]
  • Lampros Lakkas, Katerina K Naka, Aris Bechlioulis, Ioannis Girdis, Anila Duni, Vasileios Koutlas, Maria Moustakli, Christos S Katsouras, Evangelia Dounousi, Lampros K Michalis. The prognostic role of myocardial strain indices and dipyridamole stress test in renal transplantation patients. Echocardiography (Mount Kisco, N.Y.). 2020 01; 37(1):62-70. doi: 10.1111/echo.14570. [PMID: 31872917]
  • Bing Huang, Zhanghua Chen, Lanlan Geng, Jun Wang, Huiying Liang, Yujie Cao, Huan Chen, Wanming Huang, Meiling Su, Hanqing Wang, Yanhui Xu, Yukun Liu, Bingtai Lu, Huifang Xian, Huiwen Li, Huilin Li, Lu Ren, Jing Xie, Liping Ye, Hongli Wang, Junhong Zhao, Peiyu Chen, Li Zhang, Shanmeizi Zhao, Ting Zhang, Banglao Xu, Di Che, Wenyue Si, Xiaoqiong Gu, Liang Zeng, Yong Wang, Dingyou Li, Yifan Zhan, David Delfouneso, Andrew M Lew, Jun Cui, Wai Ho Tang, Yan Zhang, Sitang Gong, Fan Bai, Min Yang, Yuxia Zhang. Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways. Cell. 2019 11; 179(5):1160-1176.e24. doi: 10.1016/j.cell.2019.10.027. [PMID: 31730855]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Carlo Moroni, Stefano Tolone, Francesco Bondanini, Orazio Schillaci, Cesare Affricano, Rosario Cassone, Achille Gaspardone, Carlo Gaudio. Endothelin-1 in hypertensive patients with ischemic heart disease. Internal and emergency medicine. 2019 10; 14(7):1119-1124. doi: 10.1007/s11739-019-02095-3. [PMID: 31069633]
  • Paul Billoir, Thomas Clavier, Arnaud Guilbert, Virginie Barbay, Marie Hélène Chrétien, Marielle Fresel, Caroline Abriou, Christophe Girault, Véronique Le Cam Duchez. Is citrate theophylline adenosine dipyridamole (CTAD) better than citrate to survey unfractionated heparin treatment? Has delayed centrifugation a real impact on this survey?. Journal of thrombosis and thrombolysis. 2019 Aug; 48(2):277-283. doi: 10.1007/s11239-019-01882-1. [PMID: 31098816]
  • Danai Kitkungvan, Linh Bui, Nils P Johnson, Monica B Patel, Amanda E Roby, Pimprapa Vejpongsa, Asim K Babar, Mohammad Madjid, Angelo Nacimbene, Sachin Kumar, Alexandra DeGolovine, K Lance Gould. Quantitative myocardial perfusion positron emission tomography and caffeine revisited with new insights on major adverse cardiovascular events and coronary flow capacity. European heart journal. Cardiovascular Imaging. 2019 Jul; 20(7):751-762. doi: 10.1093/ehjci/jez080. [PMID: 31056681]
  • Joseph Longo, Peter J Mullen, Rosemary Yu, Jenna E van Leeuwen, Mehdi Masoomian, Dixon T S Woon, Yuzhuo Wang, Eric X Chen, Robert J Hamilton, Joan M Sweet, Theodorus H van der Kwast, Neil E Fleshner, Linda Z Penn. An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer. Molecular metabolism. 2019 07; 25(?):119-130. doi: 10.1016/j.molmet.2019.04.003. [PMID: 31023626]
  • Shriram M Pathak, Kerstin Julia Schaefer, Masoud Jamei, David B Turner. Biopharmaceutic IVIVE-Mechanistic Modeling of Single- and Two-Phase In Vitro Experiments to Obtain Drug-Specific Parameters for Incorporation Into PBPK Models. Journal of pharmaceutical sciences. 2019 04; 108(4):1604-1618. doi: 10.1016/j.xphs.2018.11.034. [PMID: 30476508]
  • Natalia Grañe-Boladeras, Declan Williams, Zlatina Tarmakova, Katarina Stevanovic, Linda A Villani, Pedram Mehrabi, K W Michael Siu, Marçal Pastor-Anglada, Imogen R Coe. Oligomerization of equilibrative nucleoside transporters: a novel regulatory and functional mechanism involving PKC and PP1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 03; 33(3):3841-3850. doi: 10.1096/fj.201800440rr. [PMID: 30521377]
  • Yongyong Liu, Xuqi Wu, Zhenwei Yu. Ginkgo leaf extract and dipyridamole injection as adjuvant treatment for acute cerebral infarction: Protocol for systemic review and meta-analysis of randomized controlled trials. Medicine. 2019 Feb; 98(8):e14643. doi: 10.1097/md.0000000000014643. [PMID: 30813204]
  • Qiong Yan, Keisuke Ina, Seiichi Chiba, Huixing Wei, Shuji Tatsukawa, Yoshihisa Fujikura. The signal pathway for the repressive effect of dipyridamole on myofibroblast transdifferentiation. Journal of cellular and molecular medicine. 2019 02; 23(2):1608-1612. doi: 10.1111/jcmm.14006. [PMID: 30451359]
  • Atsushi Kambayashi, Jennifer B Dressman. Predicting the Changes in Oral Absorption of Weak Base Drugs Under Elevated Gastric pH Using an In Vitro-In Silico-In Vivo Approach: Case Examples-Dipyridamole, Prasugrel, and Nelfinavir. Journal of pharmaceutical sciences. 2019 Jan; 108(1):584-591. doi: 10.1016/j.xphs.2018.11.008. [PMID: 30423339]
  • Sanjaykumar Patel, Wei Zhu, Binfeng Xia, Navneet Sharma, Andre Hermans, Jason D Ehrick, Filippos Kesisoglou, Justin Pennington. Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs. Journal of pharmaceutical sciences. 2019 01; 108(1):574-583. doi: 10.1016/j.xphs.2018.10.051. [PMID: 30395833]
  • Alessandro Mantovani, Stefano Bonapace, Gianluigi Lunardi, Matteo Salgarello, Clementina Dugo, Stefania Gori, Enrico Barbieri, Giuseppe Verlato, Reijo Laaksonen, Christopher D Byrne, Giovanni Targher. Association of Plasma Ceramides With Myocardial Perfusion in Patients With Coronary Artery Disease Undergoing Stress Myocardial Perfusion Scintigraphy. Arteriosclerosis, thrombosis, and vascular biology. 2018 12; 38(12):2854-2861. doi: 10.1161/atvbaha.118.311927. [PMID: 30571175]
  • Di Tan, Jia-Rui Wu, Ying-Ying Cui, Yi Zhao, Dan Zhang, Shi Liu, Bing Zhang. Ginkgo Leaf Extract and Dipyridamole Injection as Adjuvant Treatment for Angina Pectoris: A Meta-Analysis of 41 Randomized Controlled Trials. Chinese journal of integrative medicine. 2018 Dec; 24(12):930-937. doi: 10.1007/s11655-018-2557-6. [PMID: 29752694]
  • Yuko Shima, Koichi Nakanishi, Yoshitsugu Kaku, Kenji Ishikura, Hiroshi Hataya, Takeshi Matsuyama, Masataka Honda, Mayumi Sako, Kandai Nozu, Ryojiro Tanaka, Kazumoto Iijima, Norishige Yoshikawa. Combination therapy with or without warfarin and dipyridamole for severe childhood IgA nephropathy: an RCT. Pediatric nephrology (Berlin, Germany). 2018 11; 33(11):2103-2112. doi: 10.1007/s00467-018-4011-6. [PMID: 29987456]
  • Yufeng Zhang, Han Wan, Maosheng Du, Huiling Deng, Jia Fu, Yu Zhang, Xiaoyan Wang, Ruiqing Liu. Capillary leak syndrome and aseptic meningitis in a patient with Kawasaki disease: A case report. Medicine. 2018 Jun; 97(23):e10716. doi: 10.1097/md.0000000000010716. [PMID: 29879013]
  • Amita Ray, Sujoy Ray. Epidural therapy for the treatment of severe pre-eclampsia in non labouring women. The Cochrane database of systematic reviews. 2017 11; 11(?):CD009540. doi: 10.1002/14651858.cd009540.pub2. [PMID: 29181841]
  • Tiziana Sampietro, Francesco Sbrana, Emilio Maria Pasanisi, Federico Bigazzi, Christina Petersen, Michele Coceani, Beatrice Dal Pino, Andrea Ripoli, Mascia Pianelli, Roberta Luciani. LDL apheresis improves coronary flow reserve on the left anterior descending artery in patients with familial hypercholesterolemia and chronic ischemic heart disease. Atherosclerosis. Supplements. 2017 Nov; 30(?):135-140. doi: 10.1016/j.atherosclerosissup.2017.05.038. [PMID: 29096829]
  • Fanny A Granat, Anne Geffré, Laetitia A Lucarelli, Jean-Pierre D Braun, Catherine Trumel, Nathalie H Bourgès-Abella. Evaluation of CTAD (citrate-theophylline-adenosine-dipyridamole) as a universal anticoagulant in dogs. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 2017 Sep; 29(5):676-682. doi: 10.1177/1040638717713793. [PMID: 28673194]
  • Yasuhiro Tsume, Kazuki Matsui, Amanda L Searls, Susumu Takeuchi, Gregory E Amidon, Duxin Sun, Gordon L Amidon. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS). European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2017 May; 102(?):126-139. doi: 10.1016/j.ejps.2017.02.042. [PMID: 28263914]
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  • Pitchai Balakumar, Wei Ern WitnessKoe, Yi Syen Gan, Soo Mei JemayPuah, Subramaniam Kuganesswari, Sunil Kumar Prajapati, Rajavel Varatharajan, Sam Annie Jayachristy, Karupiah Sundram, Mohd Baidi Bahari. Effects of pre and post-treatments with dipyridamole in gentamicin-induced acute nephrotoxicity in the rat. Regulatory toxicology and pharmacology : RTP. 2017 Mar; 84(?):35-44. doi: 10.1016/j.yrtph.2016.12.007. [PMID: 27993652]
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