Fucoxanthinol (BioDeep_00000179246)

   

human metabolite blood metabolite natural product


代谢物信息卡片


18-(2,4-dihydroxy-2,6,6-trimethylcyclohexylidene)-1-{4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl}-3,7,12,16-tetramethyloctadeca-3,5,7,9,11,13,15,17-octaen-2-one

化学式: C40H56O5 (616.4127526)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 76%

分子结构信息

SMILES: CC(C=C=C1C(C)(C)CC(O)CC1(C)O)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C(=O)CC12OC1(C)CC(O)CC2(C)C
InChI: InChI=1S/C40H56O5/c1-28(17-13-18-30(3)21-22-35-36(5,6)23-32(41)25-38(35,9)44)15-11-12-16-29(2)19-14-20-31(4)34(43)27-40-37(7,8)24-33(42)26-39(40,10)45-40/h11-21,32-33,41-42,44H,23-27H2,1-10H3

描述信息

同义名列表

2 个代谢物同义名

18-(2,4-dihydroxy-2,6,6-trimethylcyclohexylidene)-1-{4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl}-3,7,12,16-tetramethyloctadeca-3,5,7,9,11,13,15,17-octaen-2-one; Fucoxanthinol



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Takashi Hashimoto, Yoshiaki Ozaki, Masashi Mizuno, Masaru Yoshida, Yosuke Nishitani, Takeshi Azuma, Akitoshi Komoto, Takashi Maoka, Yuka Tanino, Kazuki Kanazawa. Pharmacokinetics of fucoxanthinol in human plasma after the oral administration of kombu extract. The British journal of nutrition. 2012 Jun; 107(11):1566-9. doi: 10.1017/s0007114511004879. [PMID: 21920061]
  • Juan Peng, Jian-Ping Yuan, Chou-Fei Wu, Jiang-Hai Wang. Fucoxanthin, a marine carotenoid present in brown seaweeds and diatoms: metabolism and bioactivities relevant to human health. Marine drugs. 2011; 9(10):1806-1828. doi: 10.3390/md9101806. [PMID: 22072997]
  • Ratih Pangestuti, Se-Kwon Kim. Neuroprotective effects of marine algae. Marine drugs. 2011; 9(5):803-818. doi: 10.3390/md9050803. [PMID: 21673890]
  • Fumiaki Beppu, Yoshimi Niwano, Takayuki Tsukui, Masashi Hosokawa, Kazuo Miyashita. Single and repeated oral dose toxicity study of fucoxanthin (FX), a marine carotenoid, in mice. The Journal of toxicological sciences. 2009 Oct; 34(5):501-10. doi: 10.2131/jts.34.501. [PMID: 19797858]
  • Takashi Hashimoto, Yoshiaki Ozaki, Mayuko Taminato, Swadesh K Das, Masashi Mizuno, Kazuto Yoshimura, Takashi Maoka, Kazuki Kanazawa. The distribution and accumulation of fucoxanthin and its metabolites after oral administration in mice. The British journal of nutrition. 2009 Jul; 102(2):242-8. doi: 10.1017/s0007114508199007. [PMID: 19173766]
  • Chie Ishikawa, Senji Tafuku, Takashi Kadekaru, Shigeki Sawada, Mariko Tomita, Taeko Okudaira, Tetsuro Nakazato, Takayoshi Toda, Jun-Nosuke Uchihara, Naoya Taira, Kazuiku Ohshiro, Takeshi Yasumoto, Takao Ohta, Naoki Mori. Anti-adult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol. International journal of cancer. 2008 Dec; 123(11):2702-12. doi: 10.1002/ijc.23860. [PMID: 18798263]
  • Akira Asai, Lina Yonekura, Akihiko Nagao. Low bioavailability of dietary epoxyxanthophylls in humans. The British journal of nutrition. 2008 Aug; 100(2):273-7. doi: 10.1017/s0007114507895468. [PMID: 18186952]
  • Hayato Maeda, Masashi Hosokawa, Tokutake Sashima, Nobuyuki Takahashi, Teruo Kawada, Kazuo Miyashita. Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. International journal of molecular medicine. 2006 Jul; 18(1):147-52. doi: 10.3892/ijmm.18.1.147. [PMID: 16786166]
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