Fosmidomycin (BioDeep_00000179209)
human metabolite blood metabolite natural product
代谢物信息卡片
Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt
化学式: C4H10NO5P (183.029658)
中文名称: 膦胺霉素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CN(C=O)O)CP(=O)(O)O
InChI: InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10)
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C258 - Antibiotic
同义名列表
15 个代谢物同义名
Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt; 3-(N-Formyl-N-hydroxy)aminopropylphosphonic acid; [3-(N-hydroxyformamido)propyl]phosphonic acid; 3-(N-Hydroxyformamido)propylphosphonic acid; 3-(N-Hydroxyformamido)propylphosphonate; Fosmidomycin monopotassium salt; Fosmidomycin monoammonium salt; Fosmidomycin monosodium salt; Fosmidomycin sodium salt; Fosmidomycin sodium; Fosmidomycinum; Fosmidomycine; Fosmidomycina; Fosfidomycin; fosmidomycin
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:443725
- PubChem: 572
- HMDB: HMDB0252468
- DrugBank: DB02948
- ChEMBL: CHEMBL203125
- Wikipedia: Fosmidomycin
- KNApSAcK: C00018263
- chemspider: 555
- CAS: 66508-53-0
- LOTUS: LTS0041783
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
6 个相关的物种来源信息
- 2 - Bacteria: LTS0041783
- 9606 - Homo sapiens: -
- 1883 - Streptomyces: LTS0041783
- 1914 - Streptomyces lavendulae: 10.1016/J.CHEMBIOL.2008.07.010
- 1914 - Streptomyces lavendulae: LTS0041783
- 2062 - Streptomycetaceae: LTS0041783
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xin Wu, Mengwei Bu, Zili Yang, Hongrui Ping, Chunlin Song, Jiang Duan, Aidong Zhang. Design and Synthesis of Fosmidomycin Analogs containing aza-Linkers and Their Biological Activity Evaluation.
Pest management science.
2023 Oct; ?(?):. doi:
10.1002/ps.7810. [PMID: 37794283] - Bahtijor Rasulov, Eero Talts, Ülo Niinemets. Spectacular Oscillations in Plant Isoprene Emission under Transient Conditions Explain the Enigmatic CO2 Response.
Plant physiology.
2016 12; 172(4):2275-2285. doi:
10.1104/pp.16.01002. [PMID: 27770061] - Bahtijor Rasulov, Eero Talts, Astrid Kännaste, Ülo Niinemets. Bisphosphonate inhibitors reveal a large elasticity of plastidic isoprenoid synthesis pathway in isoprene-emitting hybrid aspen.
Plant physiology.
2015 Jun; 168(2):532-48. doi:
10.1104/pp.15.00470. [PMID: 25926480] - Xuhong Du, Chenlu Zhang, Wanli Guo, Weibo Jin, Zongsuo Liang, Xijun Yan, Zhixin Guo, Yan Liu, Dongfeng Yang. Nitric Oxide Plays a Central Role in Water Stress-Induced Tanshinone Production in Salvia miltiorrhiza Hairy Roots.
Molecules (Basel, Switzerland).
2015 Apr; 20(5):7574-85. doi:
10.3390/molecules20057574. [PMID: 25919278] - Padmesh P Pillai, Aswati R Nair. Hypericin biosynthesis in Hypericum hookerianum Wight and Arn: investigation on biochemical pathways using metabolite inhibitors and suppression subtractive hybridization.
Comptes rendus biologies.
2014 Oct; 337(10):571-80. doi:
10.1016/j.crvi.2014.08.002. [PMID: 25282172] - Rebecca J Malott, Chia-Hung Wu, Tracy D Lee, Trevor J Hird, Nathan F Dalleska, James E A Zlosnik, Dianne K Newman, David P Speert. Fosmidomycin decreases membrane hopanoids and potentiates the effects of colistin on Burkholderia multivorans clinical isolates.
Antimicrobial agents and chemotherapy.
2014 Sep; 58(9):5211-9. doi:
10.1128/aac.02705-14. [PMID: 24957830] - Alexandre Huchelmann, Clément Gastaldo, Mickaël Veinante, Ying Zeng, Dimitri Heintz, Denis Tritsch, Hubert Schaller, Michel Rohmer, Thomas J Bach, Andréa Hemmerlin. S-carvone suppresses cellulase-induced capsidiol production in Nicotiana tabacum by interfering with protein isoprenylation.
Plant physiology.
2014 Feb; 164(2):935-50. doi:
10.1104/pp.113.232546. [PMID: 24367019] - Amanda Haymond, Chinchu Johny, Tyrone Dowdy, Brandon Schweibenz, Karen Villarroel, Richard Young, Clark J Mantooth, Trishal Patel, Jessica Bases, Geraldine San Jose, Emily R Jackson, Cynthia S Dowd, Robin D Couch. Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase).
PloS one.
2014; 9(8):e106243. doi:
10.1371/journal.pone.0106243. [PMID: 25171339] - Se Kim, Hagen Schlicke, Kalie Van Ree, Kristine Karvonen, Anant Subramaniam, Andreas Richter, Bernhard Grimm, Janet Braam. Arabidopsis chlorophyll biosynthesis: an essential balance between the methylerythritol phosphate and tetrapyrrole pathways.
The Plant cell.
2013 Dec; 25(12):4984-93. doi:
10.1105/tpc.113.119172. [PMID: 24363312] - Xia-Nan Zhang, Zhi-Shuang Wang, Wei Gao, Lu-Qi Huang. [Effects on Salvia miltiorrhiza hairy roots of tanshinones content accumulation after treated with fosmidomycin].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2013 Dec; 38(24):4263-6. doi:
". [PMID: 24791527] - Parvin Ramak, Shahrokh Kazempour Osaloo, Hassan Ebrahimzadeh, Mozafar Sharifi, Mehrdad Behmanesh. Inhibition of the mevalonate pathway enhances carvacrol biosynthesis and DXR gene expression in shoot cultures of Satureja khuzistanica Jamzad.
Journal of plant physiology.
2013 Sep; 170(13):1187-93. doi:
10.1016/j.jplph.2013.03.013. [PMID: 23611428] - Matthias Witschel, Franz Röhl, Ricarda Niggeweg, Trevor Newton. In search of new herbicidal inhibitors of the non-mevalonate pathway.
Pest management science.
2013 May; 69(5):559-63. doi:
10.1002/ps.3479. [PMID: 23471898] - Ziru Li, Thomas D Sharkey. Metabolic profiling of the methylerythritol phosphate pathway reveals the source of post-illumination isoprene burst from leaves.
Plant, cell & environment.
2013 Feb; 36(2):429-37. doi:
10.1111/j.1365-3040.2012.02584.x. [PMID: 22831282] - Mei Han, Simon C Heppel, Tao Su, Jochen Bogs, Yuangang Zu, Zhigang An, Thomas Rausch. Enzyme inhibitor studies reveal complex control of methyl-D-erythritol 4-phosphate (MEP) pathway enzyme expression in Catharanthus roseus.
PloS one.
2013; 8(5):e62467. doi:
10.1371/journal.pone.0062467. [PMID: 23650515] - Amy M Trowbridge, Dolores Asensio, Allyson S D Eller, Danielle A Way, Michael J Wilkinson, Jörg-Peter Schnitzler, Robert B Jackson, Russell K Monson. Contribution of various carbon sources toward isoprene biosynthesis in poplar leaves mediated by altered atmospheric CO2 concentrations.
PloS one.
2012; 7(2):e32387. doi:
10.1371/journal.pone.0032387. [PMID: 22384238] - Tomoko Toyama, Michiru Tahara, Kisaburo Nagamune, Kenji Arimitsu, Yoshio Hamashima, Nirianne M Q Palacpac, Hiroshi Kawaide, Toshihiro Horii, Kazuyuki Tanabe. Gibberellin biosynthetic inhibitors make human malaria parasite Plasmodium falciparum cells swell and rupture to death.
PloS one.
2012; 7(3):e32246. doi:
10.1371/journal.pone.0032246. [PMID: 22412858] - Shashi Kumar, Frederick M Hahn, Edward Baidoo, Talwinder S Kahlon, Delilah F Wood, Colleen M McMahan, Katrina Cornish, Jay D Keasling, Henry Daniell, Maureen C Whalen. Remodeling the isoprenoid pathway in tobacco by expressing the cytoplasmic mevalonate pathway in chloroplasts.
Metabolic engineering.
2012 Jan; 14(1):19-28. doi:
10.1016/j.ymben.2011.11.005. [PMID: 22123257] - Dongfeng Yang, Xuhong Du, Xiao Liang, Ruilian Han, Zongsuo Liang, Yan Liu, Fenghua Liu, Jianjun Zhao. Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots.
PloS one.
2012; 7(11):e46797. doi:
10.1371/journal.pone.0046797. [PMID: 23209548] - Sameh S M Soliman, Rong Tsao, Manish N Raizada. Chemical inhibitors suggest endophytic fungal paclitaxel is derived from both mevalonate and non-mevalonate-like pathways.
Journal of natural products.
2011 Dec; 74(12):2497-504. doi:
10.1021/np200303v. [PMID: 22103292] - Juri Battilana, Francesco Emanuelli, Giorgio Gambino, Ivana Gribaudo, Flavia Gasperi, Paul K Boss, Maria Stella Grando. Functional effect of grapevine 1-deoxy-D-xylulose 5-phosphate synthase substitution K284N on Muscat flavour formation.
Journal of experimental botany.
2011 Nov; 62(15):5497-508. doi:
10.1093/jxb/err231. [PMID: 21868399] - Rieta Gols, James M Bullock, Marcel Dicke, Tibor Bukovinszky, Jeffrey A Harvey. Smelling the wood from the trees: non-linear parasitoid responses to volatile attractants produced by wild and cultivated cabbage.
Journal of chemical ecology.
2011 Aug; 37(8):795-807. doi:
10.1007/s10886-011-9993-5. [PMID: 21748300] - Sethu C Nair, Carrie F Brooks, Christopher D Goodman, Angelika Sturm, Angelika Strurm, Geoffrey I McFadden, Sandeep Sundriyal, Justin L Anglin, Yongcheng Song, Silvia N J Moreno, Boris Striepen. Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.
The Journal of experimental medicine.
2011 Jul; 208(7):1547-59. doi:
10.1084/jem.20110039. [PMID: 21690250] - Wei Wen, Rongmin Yu. Artemisinin biosynthesis and its regulatory enzymes: Progress and perspective.
Pharmacognosy reviews.
2011 Jul; 5(10):189-94. doi:
10.4103/0973-7847.91118. [PMID: 22279377] - Bahtijor Rasulov, Katja Hüve, Agu Laisk, Ülo Niinemets. Induction of a longer term component of isoprene release in darkened aspen leaves: origin and regulation under different environmental conditions.
Plant physiology.
2011 Jun; 156(2):816-31. doi:
10.1104/pp.111.176222. [PMID: 21502186] - Claudia E Vickers, Malcolm Possell, Jullada Laothawornkitkul, Annette C Ryan, C Nicholas Hewitt, Philip M Mullineaux. Isoprene synthesis in plants: lessons from a transgenic tobacco model.
Plant, cell & environment.
2011 Jun; 34(6):1043-1053. doi:
10.1111/j.1365-3040.2011.02303.x. [PMID: 21388420] - Baichen Zhang, Kristin M Watts, Dana Hodge, Lisa M Kemp, David A Hunstad, Leslie M Hicks, Audrey R Odom. A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.
Biochemistry.
2011 May; 50(17):3570-7. doi:
10.1021/bi200113y. [PMID: 21438569] - Kirti Mishra, Aditya P Dash, Nrisingha Dey. Andrographolide: A Novel Antimalarial Diterpene Lactone Compound from Andrographis paniculata and Its Interaction with Curcumin and Artesunate.
Journal of tropical medicine.
2011; 2011(?):579518. doi:
10.1155/2011/579518. [PMID: 21760808] - William N Hunter. Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites.
Current topics in medicinal chemistry.
2011; 11(16):2048-59. doi:
10.2174/156802611796575867. [PMID: 21619509] - Ravi S Singh, Rishi K Gara, Pardeep K Bhardwaj, Anish Kaachra, Sonia Malik, Ravi Kumar, Madhu Sharma, Paramvir S Ahuja, Sanjay Kumar. Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston].
BMC molecular biology.
2010 Nov; 11(?):88. doi:
10.1186/1471-2199-11-88. [PMID: 21092138] - Katja Behnke, Andreas Kaiser, Ina Zimmer, Nicolas Brüggemann, Dennis Janz, Andrea Polle, Rüdiger Hampp, Robert Hänsch, Jennifer Popko, Philippe Schmitt-Kopplin, Barbara Ehlting, Heinz Rennenberg, Csengele Barta, Francesco Loreto, Jörg-Peter Schnitzler. RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis.
Plant molecular biology.
2010 Sep; 74(1-2):61-75. doi:
10.1007/s11103-010-9654-z. [PMID: 20526857] - Anuruk Choemunng, Kesara Na-Bangchang. An alternative liquid chromatography-mass spectrometric method for the determination of azithromycin in human plasma and its application to pharmacokinetic study of patients with malaria.
The Southeast Asian journal of tropical medicine and public health.
2010 Sep; 41(5):1048-58. doi:
NULL. [PMID: 21073024] - Mengsu Huang, Christian Abel, Reza Sohrabi, Jana Petri, Ina Haupt, John Cosimano, Jonathan Gershenzon, Dorothea Tholl. Variation of herbivore-induced volatile terpenes among Arabidopsis ecotypes depends on allelic differences and subcellular targeting of two terpene synthases, TPS02 and TPS03.
Plant physiology.
2010 Jul; 153(3):1293-310. doi:
10.1104/pp.110.154864. [PMID: 20463089] - Anurak Cheoymang, Kesara Na-Bangchang. A high-throughput colorimetric-based bioassay method for determination of fosmidomycin in plasma and urine and application for pharmacokinetic study.
Journal of pharmacological and toxicological methods.
2010 May; 61(3):346-50. doi:
10.1016/j.vascn.2010.02.012. [PMID: 20188200] - Iris F Kappers, Francel W A Verstappen, Ludo L P Luckerhoff, Harro J Bouwmeester, Marcel Dicke. Genetic variation in jasmonic acid- and spider mite-induced plant volatile emission of cucumber accessions and attraction of the predator Phytoseiulus persimilis.
Journal of chemical ecology.
2010 May; 36(5):500-12. doi:
10.1007/s10886-010-9782-6. [PMID: 20383796] - Malcolm Possell, Annette Ryan, Claudia E Vickers, Philip M Mullineaux, C Nicholas Hewitt. Effects of fosmidomycin on plant photosynthesis as measured by gas exchange and chlorophyll fluorescence.
Photosynthesis research.
2010 Apr; 104(1):49-59. doi:
10.1007/s11120-009-9504-5. [PMID: 19915954] - Liting Lim, Geoffrey Ian McFadden. The evolution, metabolism and functions of the apicoplast.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
2010 Mar; 365(1541):749-63. doi:
10.1098/rstb.2009.0273. [PMID: 20124342] - Maaike Bruinsma, Sarah van Broekhoven, Erik H Poelman, Maarten A Posthumus, Martin J Müller, Joop J A van Loon, Marcel Dicke. Inhibition of lipoxygenase affects induction of both direct and indirect plant defences against herbivorous insects.
Oecologia.
2010 Feb; 162(2):393-404. doi:
10.1007/s00442-009-1459-x. [PMID: 19806367] - Jian Wen Wang, Li Ping Zheng, Ben Zhang, Ting Zou. Stimulation of artemisinin synthesis by combined cerebroside and nitric oxide elicitation in Artemisia annua hairy roots.
Applied microbiology and biotechnology.
2009 Nov; 85(2):285-92. doi:
10.1007/s00253-009-2090-9. [PMID: 19562334] - Kirti Mishra, Aditya P Dash, Bijay K Swain, Nrisingha Dey. Anti-malarial activities of Andrographis paniculata and Hedyotis corymbosa extracts and their combination with curcumin.
Malaria journal.
2009 Feb; 8(?):26. doi:
10.1186/1475-2875-8-26. [PMID: 19216765] - Deepak Ganjewala, Shiv Kumar, Rajesh Luthra. An account of cloned genes of Methyl-erythritol-4-phosphate pathway of isoprenoid biosynthesis in plants.
Current issues in molecular biology.
2009; 11 Suppl 1(?):i35-45. doi:
. [PMID: 19193963] - Esther Gerber, Andréa Hemmerlin, Michael Hartmann, Dimitri Heintz, Marie-Andrée Hartmann, Jérôme Mutterer, Manuel Rodríguez-Concepción, Albert Boronat, Alain Van Dorsselaer, Michel Rohmer, Dring N Crowell, Thomas J Bach. The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells.
The Plant cell.
2009 Jan; 21(1):285-300. doi:
10.1105/tpc.108.063248. [PMID: 19136647] - Violeta Velikova, Silvano Fares, Francesco Loreto. Isoprene and nitric oxide reduce damages in leaves exposed to oxidative stress.
Plant, cell & environment.
2008 Dec; 31(12):1882-94. doi:
10.1111/j.1365-3040.2008.01893.x. [PMID: 18811730] - Ronnatrai Ruangweerayut, Sornchai Looareesuwan, David Hutchinson, Anurak Chauemung, Vick Banmairuroi, Kesara Na-Bangchang. Assessment of the pharmacokinetics and dynamics of two combination regimens of fosmidomycin-clindamycin in patients with acute uncomplicated falciparum malaria.
Malaria journal.
2008 Oct; 7(?):225. doi:
10.1186/1475-2875-7-225. [PMID: 18973702] - Karolina Skorupinska-Tudek, Jaroslaw Poznanski, Jacek Wojcik, Tomasz Bienkowski, Izabela Szostkiewicz, Monika Zelman-Femiak, Agnieszka Bajda, Tadeusz Chojnacki, Olga Olszowska, Jacob Grunler, Odile Meyer, Michel Rohmer, Witold Danikiewicz, Ewa Swiezewska. Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants.
The Journal of biological chemistry.
2008 Jul; 283(30):21024-35. doi:
10.1074/jbc.m706069200. [PMID: 18502754] - Roland Mumm, Maarten A Posthumus, Marcel Dicke. Significance of terpenoids in induced indirect plant defence against herbivorous arthropods.
Plant, cell & environment.
2008 Apr; 31(4):575-85. doi:
10.1111/j.1365-3040.2008.01783.x. [PMID: 18208515] - Gen-ichiro Arimura, Stefan Garms, Massimo Maffei, Simone Bossi, Birgit Schulze, Margit Leitner, Axel Mithöfer, Wilhelm Boland. Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling.
Planta.
2008 Jan; 227(2):453-64. doi:
10.1007/s00425-007-0631-y. [PMID: 17924138] - Melissa J Towler, Pamela J Weathers. Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways.
Plant cell reports.
2007 Dec; 26(12):2129-36. doi:
10.1007/s00299-007-0420-x. [PMID: 17710406] - Laura D Tatar, Cristina L Marolda, Andrew N Polischuk, Deborah van Leeuwen, Miguel A Valvano. An Escherichia coli undecaprenyl-pyrophosphate phosphatase implicated in undecaprenyl phosphate recycling.
Microbiology (Reading, England).
2007 Aug; 153(Pt 8):2518-2529. doi:
10.1099/mic.0.2007/006312-0. [PMID: 17660416] - Rachida Tahar, Leonardo K Basco. Molecular epidemiology of malaria in Cameroon. XXV. In vitro activity of fosmidomycin and its derivatives against fresh clinical isolates of Plasmodium falciparum and sequence analysis of 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
The American journal of tropical medicine and hygiene.
2007 Aug; 77(2):214-20. doi:
. [PMID: 17690389] - Kesara Na-Bangchang, Ronnatrai Ruengweerayut, Juntra Karbwang, Anurak Chauemung, David Hutchinson. Pharmacokinetics and pharmacodynamics of fosmidomycin monotherapy and combination therapy with clindamycin in the treatment of multidrug resistant falciparum malaria.
Malaria journal.
2007 May; 6(?):70. doi:
10.1186/1475-2875-6-70. [PMID: 17531088] - Alexandros S Botsaris. Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal.
Journal of ethnobiology and ethnomedicine.
2007 May; 3(?):18. doi:
10.1186/1746-4269-3-18. [PMID: 17472740] - Anurak Cheoymang, David Hudchinton, Deborah Kioy, Kesara Na-Bangchang. Bioassay for determination of fosmidomycin in plasma and urine: application for pharmacokinetic dose optimisation.
Journal of microbiological methods.
2007 Apr; 69(1):65-9. doi:
10.1016/j.mimet.2006.11.018. [PMID: 17258829] - Lorenzo Carretero-Paulet, Albert Cairó, Patricia Botella-Pavía, Oscar Besumbes, Narciso Campos, Albert Boronat, Manuel Rodríguez-Concepción. Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase.
Plant molecular biology.
2006 Nov; 62(4-5):683-95. doi:
10.1007/s11103-006-9051-9. [PMID: 16941216] - Stefan Bartram, Andreas Jux, Gerd Gleixner, Wilhelm Boland. Dynamic pathway allocation in early terpenoid biosynthesis of stress-induced lima bean leaves.
Phytochemistry.
2006 Aug; 67(15):1661-72. doi:
10.1016/j.phytochem.2006.02.004. [PMID: 16580034] - Csengele Barta, Francesco Loreto. The relationship between the methyl-erythritol phosphate pathway leading to emission of volatile isoprenoids and abscisic acid content in leaves.
Plant physiology.
2006 Aug; 141(4):1676-83. doi:
10.1104/pp.106.083063. [PMID: 16766667] - Susanna Sauret-Güeto, Patricia Botella-Pavía, Ursula Flores-Pérez, Jaime F Martínez-García, Carolina San Román, Patricia León, Albert Boronat, Manuel Rodríguez-Concepción. Plastid cues posttranscriptionally regulate the accumulation of key enzymes of the methylerythritol phosphate pathway in Arabidopsis.
Plant physiology.
2006 May; 141(1):75-84. doi:
10.1104/pp.106.079855. [PMID: 16531478] - Marguerite Kasidimoko Nkembo, Jung-Bum Lee, Takeshi Nakagiri, Toshimitsu Hayashi. Involvement of 2-C-methyl-D-erythritol-4-phosphate pathway in biosynthesis of aphidicolin-like tetracyclic diterpene of Scoparia dulcis.
Chemical & pharmaceutical bulletin.
2006 May; 54(5):758-60. doi:
10.1248/cpb.54.758. [PMID: 16651787] - K Na-Bangchang, V Banmairuroi, B Kamanikom, D Kiod. An alternative high-performance liquid chromatographic method for determination of clindamycin in plasma.
The Southeast Asian journal of tropical medicine and public health.
2006 Jan; 37(1):177-84. doi:
NULL. [PMID: 16771232] - M José Gil, Alberto Coego, Brigitte Mauch-Mani, Lucia Jordá, Pablo Vera. The Arabidopsis csb3 mutant reveals a regulatory link between salicylic acid-mediated disease resistance and the methyl-erythritol 4-phosphate pathway.
The Plant journal : for cell and molecular biology.
2005 Oct; 44(1):155-66. doi:
10.1111/j.1365-313x.2005.02517.x. [PMID: 16167903] - Lucian O Copolovici, Iolanda Filella, Joan Llusià, Ulo Niinemets, Josep Peñuelas. The capacity for thermal protection of photosynthetic electron transport varies for different monoterpenes in Quercus ilex.
Plant physiology.
2005 Sep; 139(1):485-96. doi:
10.1104/pp.105.065995. [PMID: 16126854] - Zoia Mincheva, Martine Courtois, Françoise Andreu, Marc Rideau, Marie-Claude Viaud-Massuard. Fosmidomycin analogues as inhibitors of monoterpenoid indole alkaloid production in Catharanthus roseus cells.
Phytochemistry.
2005 Aug; 66(15):1797-803. doi:
10.1016/j.phytochem.2005.06.002. [PMID: 16054176] - Violeta Velikova, Paola Pinelli, Stefania Pasqualini, Lara Reale, Francesco Ferranti, Francesco Loreto. Isoprene decreases the concentration of nitric oxide in leaves exposed to elevated ozone.
The New phytologist.
2005 May; 166(2):419-25. doi:
10.1111/j.1469-8137.2005.01409.x. [PMID: 15819906] - Daniela Hampel, Armin Mosandl, Matthias Wüst. Induction of de novo volatile terpene biosynthesis via cytosolic and plastidial pathways by methyl jasmonate in foliage of Vitis vinifera L.
Journal of agricultural and food chemistry.
2005 Apr; 53(7):2652-7. doi:
10.1021/jf040421q. [PMID: 15796607] - Zhi Liu, Long-Jiang Yu, Chun-Yan Li, Chun-Fang Zhao. [Effects of fosmidomycin and lovastatin treatment on taxol biosynthesis in suspension culture cells of Taxus chinensis].
Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology.
2005 Apr; 31(2):199-204. doi:
. [PMID: 15840939] - Arturo Guevara-García, Carolina San Román, Analilia Arroyo, María Elena Cortés, María de la Luz Gutiérrez-Nava, Patricia León. Characterization of the Arabidopsis clb6 mutant illustrates the importance of posttranscriptional regulation of the methyl-D-erythritol 4-phosphate pathway.
The Plant cell.
2005 Feb; 17(2):628-43. doi:
10.1105/tpc.104.028860. [PMID: 15659625] - Martine Courtois, Zoia Mincheva, Françoise Andreu, Marc Rideau, Marie-Claude Viaud-Massuard. Synthesis and biological evaluation with plant cells of new fosmidomycin analogues containing a benzoxazolone or oxazolopyridinone ring.
Journal of enzyme inhibition and medicinal chemistry.
2004 Dec; 19(6):559-65. doi:
10.1080/14756360400004615. [PMID: 15662959] - Surang Engprasert, Futoshi Taura, Makoto Kawamukai, Yukihiro Shoyama. Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq.
BMC plant biology.
2004 Nov; 4(?):18. doi:
10.1186/1471-2229-4-18. [PMID: 15550168] - Stéphane Bronner, Corinne Renault, Martin Hintz, Jochen Wiesner, Hassan Jomaa, Henri Monteil, François Jehl. Determination of fosmidomycin in human serum and urine by capillary electrophoresis.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2004 Jul; 806(2):255-61. doi:
10.1016/j.jchromb.2004.04.002. [PMID: 15171936] - Francesco Loreto, Paola Pinelli, Fausto Manes, Hannes Kollist. Impact of ozone on monoterpene emissions and evidence for an isoprene-like antioxidant action of monoterpenes emitted by Quercus ilex leaves.
Tree physiology.
2004 Apr; 24(4):361-7. doi:
10.1093/treephys/24.4.361. [PMID: 14757575] - Manuel Rodríguez-Concepción, Oriol Forés, Jaime F Martinez-García, Victor González, Michael A Phillips, Albert Ferrer, Albert Boronat. Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development.
The Plant cell.
2004 Jan; 16(1):144-56. doi:
10.1105/tpc.016204. [PMID: 14660801] - Yasuyo Yamazaki, Mariko Kitajima, Masanori Arita, Hiromitsu Takayama, Hiroshi Sudo, Mami Yamazaki, Norio Aimi, Kazuki Saito. Biosynthesis of camptothecin. In silico and in vivo tracer study from [1-13C]glucose.
Plant physiology.
2004 Jan; 134(1):161-70. doi:
10.1104/pp.103.029389. [PMID: 14657405] - Jochen Wiesner, Regina Ortmann, Hassan Jomaa, Martin Schlitzer. New antimalarial drugs.
Angewandte Chemie (International ed. in English).
2003 Nov; 42(43):5274-93. doi:
10.1002/anie.200200569. [PMID: 14613157] - V S Saakov. Alternative pathways of carotenoid biosynthesis in prokaryotes and eukaryotes.
Doklady. Biochemistry and biophysics.
2003 Sep; 392(?):294-300. doi:
10.1023/a:1026107317349. [PMID: 15255207] - Oliver Laule, Andreas Fürholz, Hur-Song Chang, Tong Zhu, Xun Wang, Peter B Heifetz, Wilhelm Gruissem, Markus Lange. Crosstalk between cytosolic and plastidial pathways of isoprenoid biosynthesis in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America.
2003 May; 100(11):6866-71. doi:
10.1073/pnas.1031755100. [PMID: 12748386] - Seung-Beom Hong, Erik H Hughes, Jacqueline V Shanks, Ka-Yiu San, Susan I Gibson. Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots.
Biotechnology progress.
2003 May; 19(3):1105-8. doi:
10.1021/bp034031k. [PMID: 12790690] - Hagit P Affek, Dan Yakir. Natural abundance carbon isotope composition of isoprene reflects incomplete coupling between isoprene synthesis and photosynthetic carbon flow.
Plant physiology.
2003 Apr; 131(4):1727-36. doi:
10.1104/pp.102.012294. [PMID: 12692331] - T Karl, R Fall, T N Rosenstiel, P Prazeller, B Larsen, G Seufert, W Lindinger. On-line analysis of the (13)CO(2) labeling of leaf isoprene suggests multiple subcellular origins of isoprene precursors.
Planta.
2002 Oct; 215(6):894-905. doi:
10.1007/s00425-002-0825-2. [PMID: 12355149] - Lorenzo Carretero-Paulet, Iván Ahumada, Nuria Cunillera, Manuel Rodríguez-Concepción, Albert Ferrer, Albert Boronat, Narciso Campos. Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway.
Plant physiology.
2002 Aug; 129(4):1581-91. doi:
10.1104/pp.003798. [PMID: 12177470] - F Loreto, V Velikova. Isoprene produced by leaves protects the photosynthetic apparatus against ozone damage, quenches ozone products, and reduces lipid peroxidation of cellular membranes.
Plant physiology.
2001 Dec; 127(4):1781-7. doi:
10.1104/pp.010497. [PMID: 11743121] - B M Lange, R E Ketchum, R B Croteau. Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis.
Plant physiology.
2001 Sep; 127(1):305-14. doi:
10.1104/pp.127.1.305. [PMID: 11553758] - M Rodríguez-Concepción, I Ahumada, E Diez-Juez, S Sauret-Güeto, L M Lois, F Gallego, L Carretero-Paulet, N Campos, A Boronat. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and plastid isoprenoid biosynthesis during tomato fruit ripening.
The Plant journal : for cell and molecular biology.
2001 Aug; 27(3):213-22. doi:
10.1046/j.1365-313x.2001.01089.x. [PMID: 11532167] - T D Sharkey, X Chen, S Yeh. Isoprene increases thermotolerance of fosmidomycin-fed leaves.
Plant physiology.
2001 Apr; 125(4):2001-6. doi:
10.1104/pp.125.4.2001. [PMID: 11299379] - H P Kuemmerle, T Murakawa, F De Santis. Pharmacokinetic evaluation of fosmidomycin, a new phosphonic acid antibiotic.
Chemioterapia : international journal of the Mediterranean Society of Chemotherapy.
1987 Apr; 6(2):113-9. doi:
NULL. [PMID: 3594633] - H P Kuemmerle, T Murakawa, H Sakamoto, N Sato, T Konishi, F De Santis. Fosmidomycin, a new phosphonic acid antibiotic. Part II: 1. Human pharmacokinetics. 2. Preliminary early phase IIa clinical studies.
International journal of clinical pharmacology, therapy, and toxicology.
1985 Oct; 23(10):521-8. doi:
NULL. [PMID: 4066076] - H P Kuemmerle, T Murakawa, K Soneoka, T Konishi. Fosmidomycin: a new phosphonic acid antibiotic. Part I: Phase I tolerance studies.
International journal of clinical pharmacology, therapy, and toxicology.
1985 Oct; 23(10):515-20. doi:
NULL. [PMID: 4066075] - T Murakawa, H Sakamoto, S Fukada, T Konishi, M Nishida. Pharmacokinetics of fosmidomycin, a new phosphonic acid antibiotic.
Antimicrobial agents and chemotherapy.
1982 Feb; 21(2):224-30. doi:
10.1128/aac.21.2.224. [PMID: 7073262] - T Tsuchiya, K Ishibashi, M Terakawa, M Nishiyama, N Itoh, H Noguchi. Pharmacokinetics and metabolism of fosmidomycin, a new phosphonic acid, in rats and dogs.
European journal of drug metabolism and pharmacokinetics.
1982 Jan; 7(1):59-64. doi:
10.1007/bf03189544. [PMID: 7067725] - Y Yokota, T Murakawa, M Nishida. In vitro synergism of FR-31564, a new phosphonic acid antibiotic.
The Journal of antibiotics.
1981 Jul; 34(7):876-83. doi:
10.7164/antibiotics.34.876. [PMID: 7287590] - H C Neu, T Kamimura. In vitro and in vivo antibacterial activity of FR-31564, a phosphonic acid antimicrobial agent.
Antimicrobial agents and chemotherapy.
1981 Jun; 19(6):1013-23. doi:
10.1128/aac.19.6.1013. [PMID: 7271270] - . .
.
. doi:
. [PMID: 11598232] - . .
.
. doi:
. [PMID: 17634747] - . .
.
. doi:
. [PMID: 15286296] - . .
.
. doi:
. [PMID: 12427975]