Felotaxel (BioDeep_00000179000)
human metabolite blood metabolite
代谢物信息卡片
化学式: C31H32N2O6 (528.226)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCC4=CC(=C(C=C4)OC)OC)C
InChI: InChI=1S/C31H32N2O6/c1-21-19-22(2)33-30(32-21)39-28(29(34)35)31(24-11-7-5-8-12-24,25-13-9-6-10-14-25)38-18-17-23-15-16-26(36-3)27(20-23)37-4/h5-16,19-20,28H,17-18H2,1-4H3,(H,34,35)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Gabriele Sauter, Sabine Wolf, Teut Risler, Bernhard Brehm. Influence of endothelin receptor antagonism on smooth muscle cell proliferation after chronic renal failure.
Journal of cardiovascular pharmacology.
2004 Nov; 44 Suppl 1(?):S165-7. doi:
10.1097/01.fjc.0000166245.28368.ae
. [PMID: 15838271] - Thiemo Pfab, Gisela Stoltenburg-Didinger, Christoph Trautner, Michael Godes, Christian Bauer, Berthold Hocher. The endothelin system in Morris hepatoma-7777: an endothelin receptor antagonist inhibits growth in vitro and in vivo.
British journal of pharmacology.
2004 Jan; 141(2):215-22. doi:
10.1038/sj.bjp.0705601
. [PMID: 14662722] - Stanislao Morgera, Juliane Schlenstedt, Pia Hambach, Markus Giessing, Serdar Deger, Berthold Hocher, Hans-Hellmut Neumayer. Combined ETA/ETB receptor blockade of human peritoneal mesothelial cells inhibits collagen I RNA synthesis.
Kidney international.
2003 Dec; 64(6):2033-40. doi:
10.1046/j.1523-1755.2003.00320.x
. [PMID: 14633125] - Martin Hasselblatt, Marion Bunte, Ralf Dringen, Arantxa Tabernero, José M Medina, Christian Giaume, Anna-Leena Sirén, Hannelore Ehrenreich. Effect of endothelin-1 on astrocytic protein content.
Glia.
2003 Jun; 42(4):390-7. doi:
10.1002/glia.10224
. [PMID: 12730959] - Berthold Hocher, Philipp Kalk, Torsten Slowinski, Michael Godes, Alexander Mach, Sophia Herzfeld, Doreen Wiesner, Petra Clara Arck, Hans-H Neumayer, Benno Nafz. ETA receptor blockade induces tubular cell proliferation and cyst growth in rats with polycystic kidney disease.
Journal of the American Society of Nephrology : JASN.
2003 Feb; 14(2):367-76. doi:
10.1097/01.asn.0000042165.63601.65
. [PMID: 12538737] - B Hocher, A Schwarz, D Reinbacher, J Jacobi, A Lun, F Priem, C Bauer, H H Neumayer, M Raschack. Effects of endothelin receptor antagonists on the progression of diabetic nephropathy.
Nephron.
2001 Feb; 87(2):161-9. doi:
10.1159/000045906
. [PMID: 11244312] - S C Wolf, F Gaschler, S Brehm, M Klaussner, K Amann, T Risler, B R Brehm. Endothelin-receptor antagonists in uremic cardiomyopathy.
Journal of cardiovascular pharmacology.
2000 Nov; 36(5 Suppl 1):S348-50. doi:
10.1097/00005344-200036051-00101
. [PMID: 11078417] - S Babaei, P Picard, A Ravandi, J C Monge, T C Lee, P Cernacek, D J Stewart. Blockade of endothelin receptors markedly reduces atherosclerosis in LDL receptor deficient mice: role of endothelin in macrophage foam cell formation.
Cardiovascular research.
2000 Oct; 48(1):158-67. doi:
10.1016/s0008-6363(00)00169-3
. [PMID: 11033118] - C Braun, T Conzelmann, S Vetter, M Schaub, W E Back, M Kirchengast, S G Tullius, P Schnülle, F J van der Woude, P Rohmeiss. Treatment with a combined endothelin A/B-receptor antagonist does not prevent chronic renal allograft rejection in rats.
Journal of cardiovascular pharmacology.
2000 Oct; 36(4):428-37. doi:
10.1097/00005344-200010000-00003
. [PMID: 11026642] - J Dupuis, A J Schwab, A Simard, P Cernacek, D J Stewart, C A Goresky. Kinetics of endothelin-1 binding in the dog liver microcirculation in vivo.
The American journal of physiology.
1999 10; 277(4):G905-14. doi:
10.1152/ajpgi.1999.277.4.g905
. [PMID: 10516158]