Dioxidine (BioDeep_00000178396)

   

human metabolite blood metabolite


代谢物信息卡片


2,3-bis(hydroxymethyl)-1-oxo-1,4-dihydro-1lambda5-quinoxalin-1-ylium-4-olate

化学式: C10H10N2O4 (222.064054)
中文名称: 2,3-喹喔啉二甲醇 1,4-二氧化物
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)N(C(=C([N+]2=O)CO)CO)[O-]
InChI: InChI=1S/C10H10N2O4/c13-5-9-10(6-14)12(16)8-4-2-1-3-7(8)11(9)15/h1-4,13-14H,5-6H2

描述信息

D009676 - Noxae > D009153 - Mutagens
D000890 - Anti-Infective Agents

同义名列表

10 个代谢物同义名

2,3-bis(hydroxymethyl)-1-oxo-1,4-dihydro-1lambda5-quinoxalin-1-ylium-4-olate; Sulfonium, trimethyl-, 2,3-bis(hydroxymethyl)quinoxaline-1,4-di-N-oxide; 2,3-bis(hydroxymethyl)-1-oxo-1H-1lambda5-quinoxalin-1-ylium-4-olate; 2,3-Di(hydroxymethyl)quinoxaline di-N-oxide; (1,4-dioxidoquinoxaline-2,3-diyl)dimethanol; 2,3-Quinoxalinedimethanol, 1,4-dioxide; 2,3-Quinoxalinedimethanol-1,4-dioxide; Chinoxalindimethanol dioxide; Dioxydine; Dioxidine



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • O Vasetska, O Zubko, M Prodanchuk, O Kravchuk, P Zhminko. EFFECT OF 2,6-DIMETHYLPYRIDINE-N-OXIDE ON THE SEVERITY OF CYTOGENETIC EFFECTS INDUCED BY DIOXIDINE IN BONE MARROW CELLS OF MICE. Georgian medical news. 2021 May; ?(314):139-145. doi: ". [PMID: 34248044]
  • Vladimir I Lozinsky, Anastasiya O Shchekoltsova, Ekaterina S Sinitskaya, Olga I Vernaya, Anastasiya V Nuzhdina, Irina V Bakeeva, Mariam G Ezernitskaya, Alexander M Semenov, Tatyana I Shabatina, Mikhail Ya Melnikov. Influence of succinylation of a wide-pore albumin cryogels on their properties, structure, biodegradability, and release dynamics of dioxidine loaded in such spongy carriers. International journal of biological macromolecules. 2020 Oct; 160(?):583-592. doi: 10.1016/j.ijbiomac.2020.05.251. [PMID: 32479937]
  • V M Shkarupa, I R Baryliak. [Mutagenesis induced with dioxidin in the Allium-test]. TSitologiia i genetika. 2006 Sep; 40(5):31-5. doi: ". [PMID: 17385416]
  • T N Alekseeva, A D Durnev, A V Kulakova, A V Oreshchenko, L V Samusenok, B N Ogarkov, S B Seredenin. [Effect of plant melanin pigment on the clastogenic effects of chemical mutagens in mice]. Eksperimental'naia i klinicheskaia farmakologiia. 2001 Nov; 64(6):56-9. doi: ". [PMID: 11871241]
  • T G Sazontova, N V Guseva, T A Lisitsina, Iu V Arkhipenko, A D Durnev. [Activity of enzymes of antioxidant protection and level of lipid peroxidation in intact NZW mice and mice exposed to mutagens]. Biulleten' eksperimental'noi biologii i meditsiny. 1997 Apr; 123(4):381-4. doi: ". [PMID: 9190174]
  • V A Zurabyan, N V Pavlovich, L N Makarovskaya, V V Ryzhkova, O K Bugaeva. [In vitro influence of biologically active factors of microorganisms on antibiotic susceptibility of Yersinia pestis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 1997; 42(11):22-5. doi: NULL. [PMID: 9463297]
  • A D Durnev, T G Sazontova, N V Guseva, S B Seredenin. [Effect of dioxidine and cyclophosphamide on lipid peroxidation and superoxide dismutase and catalase activity in C57Bl/6 and BALB/c mice]. Biulleten' eksperimental'noi biologii i meditsiny. 1996 May; 121(5):528-32. doi: ". [PMID: 8744129]
  • M P Nikolaev, A I Logunov, L G Tsyrulńikova, D S Dzhalilov. [Clinical and biochemical aspects in the treatment of acute maxillary sinusitis with antioxidants]. Vestnik otorinolaringologii. 1994 Jan; ?(1):22-6. doi: . [PMID: 7785133]
  • B Ia Ryzhavskiĭ, E A Ivashkov. [The morphofunctional characteristics of the adrenal cortical substance after exposure to an adrenocorticolytic agent]. Morfologiia (Saint Petersburg, Russia). 1992 May; 102(5):112-20. doi: ". [PMID: 1343234]
  • B G Nuzov. [The effect of millet oil on the regeneration process in trophic ulcers]. Farmakologiia i toksikologiia. 1990 Sep; 53(5):62-4. doi: ". [PMID: 2253756]
  • A V Nikitin, S I Simvolokov, E P Karpukhina. [The clinico-immunological efficacy of dioxidine in the combined treatment of acute abscessing pneumonias in persons who abuse alcohol]. Terapevticheskii arkhiv. 1990; 62(1):78-81. doi: ". [PMID: 2333626]
  • T R Ponomareva, V A Malakhova, V S Ana'nev. [Pharmacokinetics of dioxidine in oncological patients in the postoperative period]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 1989 Sep; 34(9):684-7. doi: NULL. [PMID: 2692530]
  • T R Ponomareva. [Sensitivity of clinical bacterial strains to dioxidine in vitro under aerobic and anaerobic conditions]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology. 1987 Mar; 32(3):199-202. doi: NULL. [PMID: 3579247]
  • T A Zinchenko, M V Starkov, E A Rudzit, L I Lisitsa. [Dioxidine and carbenicillin in Pseudomonas aeruginosa pyelonephritis in rats]. Farmakologiia i toksikologiia. 1982 Jan; 45(1):65-70. doi: . [PMID: 7056384]