2-Aminobenzamide (BioDeep_00000017839)

   

human metabolite


代谢物信息卡片


2-Carbamoylaniline, anthranilimidic acid

化学式: C7H8N2O (136.06365979999998)
中文名称: 2-氨基苯甲酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C(=C1)C(=O)N)N
InChI: InChI=1S/C7H8N2O/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H2,9,10)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
Acetaldehyde scavenger for polyethylene beverage bottles.
Acetaldehyde scavenger for polyethylene beverage bottles
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

15 个代谢物同义名

2-Carbamoylaniline, anthranilimidic acid; 2-amino-Benzamideanthranilamide; 2-Aminobenzene-1-carboximidate; Benzoic acid, 2-amino-, amide; Anthranilic acid amide; Anthranilimidic acid; ortho-Aminobenzamide; benzamide, 2-amino-; 2-Carbamoylaniline; 2-amino-Benzamide; O-amino-Benzamide; O-Aminobenzamide; 2-AMINOBENZAMIDE; Anthranilamide; Aminobenzamide



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Xing-Lin Xie, Guo-Hua Ye, Jun-Juan Xue, Tong Su, Gui-Hua Tang, Wei Li, Sheng Yin. A new prenylated coumarin and a new anthranilamide derivative from Evodia lepta. Journal of Asian natural products research. 2020 May; 22(5):413-417. doi: 10.1080/10286020.2019.1670169. [PMID: 31565970]
  • Zhan-Xing Hu, Li-Hua Zhao, Hong-Yu Tang, Haji Aker Aisa, Yu Zhang, Xiao-Jiang Hao. Seven new anthranilamide derivatives from Aconitum apetalum. Fitoterapia. 2018 Jul; 128(?):73-78. doi: 10.1016/j.fitote.2018.05.008. [PMID: 29772296]
  • Changjiang Huang, Wenzhi Wang, Yao Li, Shijun Zhang, Fancui Meng, Weiren Xu, Jing Yuan, Ligong Chen. Synthesis and evaluation of anthranilamide-based derivatives as FXa inhibitors. Oncotarget. 2017 Jun; 8(23):37186-37199. doi: 10.18632/oncotarget.16427. [PMID: 28415603]
  • Soo Hyun Lee, Wonhwa Lee, ThiHa Nguyen, Il Soo Um, Jong-Sup Bae, Eunsook Ma. Synthesis and Thrombin, Factor Xa and U46619 Inhibitory Effects of Non-Amidino and Amidino N²-Thiophenecarbonyl- and N²-Tosylanthranilamides. International journal of molecular sciences. 2017 May; 18(6):. doi: 10.3390/ijms18061144. [PMID: 28561744]
  • Thomas Klarić, Ivan Gudelj. HILIC-UPLC Analysis of Brain Tissue N-Glycans. Methods in molecular biology (Clifton, N.J.). 2017; 1503(?):207-216. doi: 10.1007/978-1-4939-6493-2_16. [PMID: 27743369]
  • Jingjing Fang, Guochen Qin, Jun Ma, Yi-Min She. Quantification of plant cell wall monosaccharides by reversed-phase liquid chromatography with 2-aminobenzamide pre-column derivatization and a non-toxic reducing reagent 2-picoline borane. Journal of chromatography. A. 2015 Oct; 1414(?):122-8. doi: 10.1016/j.chroma.2015.08.038. [PMID: 26342873]
  • Vrajesh Pandya, Mukul Jain, Ganes Chakrabarti, Hitesh Soni, Bhavesh Parmar, Balaji Chaugule, Jigar Patel, Tushar Jarag, Jignesh Joshi, Nirav Joshi, Akshyaya Rath, Vishal Unadkat, Bhavesh Sharma, Haresh Ajani, Jeevan Kumar, Kalapatapu V V M Sairam, Harilal Patel, Pankaj Patel. Synthesis and structure-activity relationship of potent, selective and orally active anthranilamide-based factor Xa inhibitors: application of weakly basic sulfoximine group as novel S4 binding element. European journal of medicinal chemistry. 2012 Dec; 58(?):136-52. doi: 10.1016/j.ejmech.2012.10.005. [PMID: 23124211]
  • Leslie Alessandri, David Ouellette, Aima Acquah, Mathew Rieser, David Leblond, Mary Saltarelli, Czeslaw Radziejewski, Taro Fujimori, Ivan Correia. Increased serum clearance of oligomannose species present on a human IgG1 molecule. mAbs. 2012 Jul; 4(4):509-20. doi: 10.4161/mabs.20450. [PMID: 22669558]
  • Ishrat Jabeen, Karin Pleban, Uwe Rinner, Peter Chiba, Gerhard F Ecker. Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein. Journal of medicinal chemistry. 2012 Apr; 55(7):3261-73. doi: 10.1021/jm201705f. [PMID: 22452412]
  • Meital Edri-Brami, Benyamin Rosental, Dana Hayoun, Michael Welt, Hila Rosen, Itzhak Wirguin, Beatrice Nefussy, Vivian E Drory, Angel Porgador, Rachel G Lichtenstein. Glycans in sera of amyotrophic lateral sclerosis patients and their role in killing neuronal cells. PloS one. 2012; 7(5):e35772. doi: 10.1371/journal.pone.0035772. [PMID: 22666317]
  • Jessica E S Bohonowych, Shuping Peng, Udhayakumar Gopal, Michael W Hance, Shane B Wing, Kelley M Argraves, Karen Lundgren, Jennifer S Isaacs. Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation. BMC cancer. 2011 Dec; 11(?):520. doi: 10.1186/1471-2407-11-520. [PMID: 22172030]
  • Ana Knežević, Jonathan Bones, Stjepan Krešimir Kračun, Olga Gornik, Pauline M Rudd, Gordan Lauc. High throughput plasma N-glycome profiling using multiplexed labelling and UPLC with fluorescence detection. The Analyst. 2011 Nov; 136(22):4670-3. doi: 10.1039/c1an15684e. [PMID: 21956149]
  • Maja Pucić, Ana Knezević, Jana Vidic, Barbara Adamczyk, Mislav Novokmet, Ozren Polasek, Olga Gornik, Sandra Supraha-Goreta, Mark R Wormald, Irma Redzić, Harry Campbell, Alan Wright, Nicholas D Hastie, James F Wilson, Igor Rudan, Manfred Wuhrer, Pauline M Rudd, Djuro Josić, Gordan Lauc. High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations. Molecular & cellular proteomics : MCP. 2011 Oct; 10(10):M111.010090. doi: 10.1074/mcp.m111.010090. [PMID: 21653738]
  • C Lowell Parsons, Jeffrey Proctor, Joel S Teichman, J Curtis Nickel, Edward Davis, Robert Evans, Paul Zupkas, Cody Phillips, Timothy Shaw, Natasha Naidu, Sulabha Argade. A multi-site study confirms abnormal glycosylation in the Tamm-Horsfall protein of patients with interstitial cystitis. The Journal of urology. 2011 Jul; 186(1):112-6. doi: 10.1016/j.juro.2011.02.2699. [PMID: 21571325]
  • Takahiro Nakano, Sachiko Sugimoto, Katsuyoshi Matsunami, Hideaki Otsuka. Dianthosaponins A-F, triterpene saponins, flavonoid glycoside, aromatic amide glucoside and γ-pyrone glucoside from Dianthus japonicus. Chemical & pharmaceutical bulletin. 2011; 59(9):1141-8. doi: 10.1248/cpb.59.1141. [PMID: 21881258]
  • Gordan Lauc, Abdelkader Essafi, Jennifer E Huffman, Caroline Hayward, Ana Knežević, Jayesh J Kattla, Ozren Polašek, Olga Gornik, Veronique Vitart, Jodie L Abrahams, Maja Pučić, Mislav Novokmet, Irma Redžić, Susan Campbell, Sarah H Wild, Fran Borovečki, Wei Wang, Ivana Kolčić, Lina Zgaga, Ulf Gyllensten, James F Wilson, Alan F Wright, Nicholas D Hastie, Harry Campbell, Pauline M Rudd, Igor Rudan. Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation. PLoS genetics. 2010 Dec; 6(12):e1001256. doi: 10.1371/journal.pgen.1001256. [PMID: 21203500]
  • Xiang-Shan Wang, Ke Yang, Jie Zhou, Shu-Jiang Tu. Facile method for the combinatorial synthesis of 2,2-disubstituted quinazolin-4(1H)-one derivatives catalyzed by iodine in ionic liquids. Journal of combinatorial chemistry. 2010 Jul; 12(4):417-21. doi: 10.1021/cc900174p. [PMID: 20334422]
  • Ada Triguero, Gleysin Cabrera, Louise Royle, David J Harvey, Pauline M Rudd, Raymond A Dwek, Muriel Bardor, Patrice Lerouge, José A Cremata. Chemical and enzymatic N-glycan release comparison for N-glycan profiling of monoclonal antibodies expressed in plants. Analytical biochemistry. 2010 May; 400(2):173-83. doi: 10.1016/j.ab.2010.01.027. [PMID: 20109437]
  • Kayo Hasehira, Shin-Ichi Nakakita, Nobumitsu Miyanishi, Wataru Sumiyoshi, Shie Hayashi, Kaoru Takegawa, Jun Hirabayashi. A comprehensive HPLC analytical system for the identification and quantification of hexoses that employs 2-aminobenzamide coupling. Journal of biochemistry. 2010 Apr; 147(4):501-9. doi: 10.1093/jb/mvp199. [PMID: 19948774]
  • David C A Neville, Raymond A Dwek, Terry D Butters. Development of a single column method for the separation of lipid- and protein-derived oligosaccharides. Journal of proteome research. 2009 Feb; 8(2):681-7. doi: 10.1021/pr800704t. [PMID: 19099509]
  • Martial Séveno, Gleysin Cabrera, Ada Triguero, Carole Burel, Jérome Leprince, Christophe Rihouey, Louis-Philippe Vézina, Marc-André D'Aoust, Pauline M Rudd, L Royle, Raymond A Dwek, David J Harvey, Patrice Lerouge, José A Cremata, Muriel Bardor. Plant N-glycan profiling of minute amounts of material. Analytical biochemistry. 2008 Aug; 379(1):66-72. doi: 10.1016/j.ab.2008.04.034. [PMID: 18482571]
  • Arjen R de Boer, Cornelis H Hokke, André M Deelder, M Wuhrer. Serum antibody screening by surface plasmon resonance using a natural glycan microarray. Glycoconjugate journal. 2008 Jan; 25(1):75-84. doi: 10.1007/s10719-007-9100-x. [PMID: 18193481]
  • Gerard J A Rouwendal, Manfred Wuhrer, Dion E A Florack, Carolien A M Koeleman, André M Deelder, Hans Bakker, Geert M Stoopen, Irma van Die, Johannes P F G Helsper, Cornelis H Hokke, Dirk Bosch. Efficient introduction of a bisecting GlcNAc residue in tobacco N-glycans by expression of the gene encoding human N-acetylglucosaminyltransferase III. Glycobiology. 2007 Mar; 17(3):334-44. doi: 10.1093/glycob/cwl078. [PMID: 17179169]
  • Marjolein L M Robijn, Carolien A M Koeleman, Manfred Wuhrer, Louise Royle, Rudolf Geyer, Raymond A Dwek, Pauline M Rudd, André M Deelder, Cornelis H Hokke. Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody. Molecular and biochemical parasitology. 2007 Feb; 151(2):148-61. doi: 10.1016/j.molbiopara.2006.10.019. [PMID: 17188765]
  • Sarah Maslen, Pawel Sadowski, Alex Adam, Kathryn Lilley, Elaine Stephens. Differentiation of isomeric N-glycan structures by normal-phase liquid chromatography-MALDI-TOF/TOF tandem mass spectrometry. Analytical chemistry. 2006 Dec; 78(24):8491-8. doi: 10.1021/ac0614137. [PMID: 17165844]
  • Teruko Konishi, Hiroshi Ono, Mayumi Ohnishi-Kameyama, Satoshi Kaneko, Tadashi Ishii. Identification of a mung bean arabinofuranosyltransferase that transfers arabinofuranosyl residues onto (1, 5)-linked alpha-L-arabino-oligosaccharides. Plant physiology. 2006 Jul; 141(3):1098-105. doi: 10.1104/pp.106.080309. [PMID: 16698899]
  • Y Nagaoka, T Maeda, Y Kawai, D Nakashima, T Oikawa, K Shimoke, T Ikeuchi, H Kuwajima, S Uesato. Synthesis and cancer antiproliferative activity of new histone deacetylase inhibitors: hydrophilic hydroxamates and 2-aminobenzamide-containing derivatives. European journal of medicinal chemistry. 2006 Jun; 41(6):697-708. doi: 10.1016/j.ejmech.2006.02.002. [PMID: 16584813]
  • Zhicong He, Lina P Aristoteli, Leonard Kritharides, Brett Garner. HPLC analysis of discrete haptoglobin isoform N-linked oligosaccharides following 2D-PAGE isolation. Biochemical and biophysical research communications. 2006 May; 343(2):496-503. doi: 10.1016/j.bbrc.2006.03.007. [PMID: 16546121]
  • Tadashi Ishii, Hiroshi Ono, Mayumi Ohnishi-Kameyama, Ikuko Maeda. Enzymic transfer of alpha-L-arabinopyranosyl residues to exogenous 1,4-linked beta-D-galacto-oligosaccharides using solubilized mung bean (Vigna radiata) hypocotyl microsomes and UDP-beta-L-arabinopyranose. Planta. 2005 Aug; 221(6):953-63. doi: 10.1007/s00425-005-1504-x. [PMID: 15846502]
  • Kate Koles, William McDowell, Radmila Mileusnic, Steven P R Rose. Glycan analysis of the chicken synaptic plasma membrane glycoproteins--a major synaptic N-glycan carries the LewisX determinant. International journal of biological sciences. 2005; 1(4):126-34. doi: 10.7150/ijbs.1.126. [PMID: 16244702]
  • Jonna M Lehtonen, Seppo Parkkila, Daniela Vullo, Angela Casini, Andrea Scozzafava, Claudiu T Supuran. Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design. Bioorganic & medicinal chemistry letters. 2004 Jul; 14(14):3757-62. doi: 10.1016/j.bmcl.2004.04.106. [PMID: 15203157]
  • Ricardo Gutiérrez Gallego, Simon R Haseley, Vincent F L van Miegem, Johannes F G Vliegenthart, Johannis P Kamerling. Identification of carbohydrates binding to lectins by using surface plasmon resonance in combination with HPLC profiling. Glycobiology. 2004 May; 14(5):373-86. doi: 10.1093/glycob/cwh052. [PMID: 14736727]
  • Claudia E Grubenmann, Christian G Frank, Andreas J Hülsmeier, Els Schollen, Gert Matthijs, Ertan Mayatepek, Eric G Berger, Markus Aebi, Thierry Hennet. Deficiency of the first mannosylation step in the N-glycosylation pathway causes congenital disorder of glycosylation type Ik. Human molecular genetics. 2004 Mar; 13(5):535-42. doi: 10.1093/hmg/ddh050. [PMID: 14709599]
  • Tadashi Ishii. A sensitive and rapid bioassay of homogalacturonan synthase using 2-aminobenzamide-labeled oligogalacturonides. Plant & cell physiology. 2002 Nov; 43(11):1386-9. doi: 10.1093/pcp/pcf150. [PMID: 12461139]
  • Anthony H Merry, David C A Neville, Louise Royle, Brian Matthews, David J Harvey, Raymond A Dwek, Pauline M Rudd. Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis. Analytical biochemistry. 2002 May; 304(1):91-9. doi: 10.1006/abio.2002.5620. [PMID: 11969192]
  • D R Wing, B Garner, V Hunnam, G Reinkensmeier, U Andersson, D J Harvey, R A Dwek, F M Platt, T D Butters. High-performance liquid chromatography analysis of ganglioside carbohydrates at the picomole level after ceramide glycanase digestion and fluorescent labeling with 2-aminobenzamide. Analytical biochemistry. 2001 Nov; 298(2):207-17. doi: 10.1006/abio.2001.5393. [PMID: 11700975]
  • A E Hills, A Patel, P Boyd, D C James. Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells. Biotechnology and bioengineering. 2001 Oct; 75(2):239-51. doi: 10.1002/bit.10022. [PMID: 11536148]
  • H Manya, Y Sato, N Eguchi, K Seiki, H Oda, H Nakajima, Y Urade, T Endo. Comparative study of the asparagine-linked sugar chains of human lipocalin-type prostaglandin D synthase purified from urine and amniotic fluid, and recombinantly expressed in Chinese hamster ovary cells. Journal of biochemistry. 2000 Jun; 127(6):1001-11. doi: 10.1093/oxfordjournals.jbchem.a022691. [PMID: 10833268]
  • F H Routier, M J Davies, K Bergemann, E F Hounsell. The glycosylation pattern of humanized IgGI antibody (D1.3) expressed in CHO cells. Glycoconjugate journal. 1997 Feb; 14(2):201-7. doi: 10.1023/a:1018589704981. [PMID: 9111137]
  • A M Gardner, F H Xu, C Fady, F J Jacoby, D C Duffey, Y Tu, A Lichtenstein. Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide. Free radical biology & medicine. 1997; 22(1-2):73-83. doi: 10.1016/s0891-5849(96)00235-3. [PMID: 8958131]