Diisopropylamine (BioDeep_00000178333)

   

human metabolite blood metabolite


代谢物信息卡片


Diisopropylamine hydrochloride

化学式: C6H15N (101.120443)
中文名称: 二异丙胺
谱图信息: 最多检出来源 Homo sapiens(blood) 98.7%

分子结构信息

SMILES: CC(C)NC(C)C
InChI: InChI=1S/C6H15N/c1-5(2)7-6(3)4/h5-7H,1-4H3



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Liyan Qiu, Cheng Zheng, Qinghe Zhao. Mechanisms of drug resistance reversal in Dox-resistant MCF-7 cells by pH-responsive amphiphilic polyphosphazene containing diisopropylamino side groups. Molecular pharmaceutics. 2012 May; 9(5):1109-17. doi: 10.1021/mp200356w. [PMID: 22494535]
  • Andy J Liedtke, Brenda C Crews, Cristina M Daniel, Anna L Blobaum, Philip J Kingsley, Kebreab Ghebreselasie, Lawrence J Marnett. Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. Journal of medicinal chemistry. 2012 Mar; 55(5):2287-300. doi: 10.1021/jm201528b. [PMID: 22263894]
  • Paul L Wood, Tara Smith, Nina Lane, M Amin Khan, Greg Ehrmantraut, Dayan B Goodenowe. Oral bioavailability of the ether lipid plasmalogen precursor, PPI-1011, in the rabbit: a new therapeutic strategy for Alzheimer's disease. Lipids in health and disease. 2011 Dec; 10(?):227. doi: 10.1186/1476-511x-10-227. [PMID: 22142382]
  • Weizhi Sun, Weibing Peng, Guoqiang Li, Tao Jiang. Design, synthesis, and sustained-release property of 1,3-cyclic propanyl phosphate ester of 18β-glycyrrhetinic acid. Chemical biology & drug design. 2011 Mar; 77(3):206-11. doi: 10.1111/j.1747-0285.2010.01077.x. [PMID: 21244638]
  • Yousef Fazaeli, Mostafa M Amini, Hamed Ashourion, Homayoun Heydari, Abbas Majdabadi, Amir Reza Jalilian, Shamsozoha Abolmaali. Grafting of a novel gold(III) complex on nanoporous MCM-41 and evaluation of its toxicity in Saccharomyces cerevisiae. International journal of nanomedicine. 2011; 6(?):3251-7. doi: 10.2147/ijn.s25449. [PMID: 22228993]
  • Asitha T Silva, Alien Nguyen, Changming Ye, Jeanmarie Verchot, Joong Ho Moon. Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts. BMC plant biology. 2010 Dec; 10(?):291. doi: 10.1186/1471-2229-10-291. [PMID: 21192827]
  • A Vaikkinen, T Kotiaho, R Kostiainen, T J Kauppila. Desorption atmospheric pressure photoionization with polydimethylsiloxane as extraction phase and sample plate material. Analytica chimica acta. 2010 Dec; 682(1-2):1-8. doi: 10.1016/j.aca.2010.09.019. [PMID: 21056710]
  • José S Casas, M Victoria Castaño, Agustín Sánchez, José Sordo, M Dolores Torres, María D Couce, Angeles Gato, Carmen Alvarez-Lorenzo, M Félix Camiña, Eduardo E Castellano. Interactions of diorganolead(IV) with 3-(2-thienyl)-2-sulfanylpropenoic acid and/or thiamine: chemical and in vitro and in vivo toxicological results. Inorganic chemistry. 2010 Mar; 49(5):2173-81. doi: 10.1021/ic901961g. [PMID: 20088549]
  • Wendy Maury, Jason P Price, Melinda A Brindley, ChoonSeok Oh, Jeffrey D Neighbors, David F Wiemer, Nickolas Wills, Susan Carpenter, Cathy Hauck, Patricia Murphy, Mark P Widrlechner, Kathleen Delate, Ganesh Kumar, George A Kraus, Ludmila Rizshsky, Basil Nikolau. Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum. Virology journal. 2009 Jul; 6(?):101. doi: 10.1186/1743-422x-6-101. [PMID: 19594941]
  • Patricia A Zunszain, Jamie Ghuman, Antony F McDonagh, Stephen Curry. Crystallographic analysis of human serum albumin complexed with 4Z,15E-bilirubin-IXalpha. Journal of molecular biology. 2008 Aug; 381(2):394-406. doi: 10.1016/j.jmb.2008.06.016. [PMID: 18602119]
  • J Donald Ostrow, Pasupati Mukerjee. Revalidation and rationale for high pKa values of unconjugated bilirubin. BMC biochemistry. 2007 May; 8(?):7. doi: 10.1186/1471-2091-8-7. [PMID: 17475001]
  • Bogna Rudolf, Marcin Palusiak, Janusz Zakrzewski, Michèle Salmain, Gérard Jaouen. Sulfhydryl-selective, covalent labeling of biomolecules with transition metallocarbonyl complexes. Synthesis of (eta5-C5H5)M(CO)3(eta1-N-maleimidato) (M = Mo, W), X-ray structure, and reactivity studies. Bioconjugate chemistry. 2005 Sep; 16(5):1218-24. doi: 10.1021/bc050073d. [PMID: 16173801]
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