Dihydroxyphenyl-valerolactone (BioDeep_00000178324)

   

human metabolite blood metabolite


代谢物信息卡片


(-)-5-(3,4-Dihydroxyphenyl)-gamma-valerolactone

化学式: C11H12O4 (208.0735552)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1COC(=O)C(C1O)(C2=CC=CC=C2)O
InChI: InChI=1S/C11H12O4/c12-9-6-7-15-10(13)11(9,14)8-4-2-1-3-5-8/h1-5,9,12,14H,6-7H2



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Donato Angelino, Diogo Carregosa, Cristina Domenech-Coca, Monia Savi, Inês Figueira, Nicoletta Brindani, Saebyeol Jang, Sukla Lakshman, Aleksey Molokin, Joseph F Urban, Cindy D Davis, Maria Alexandra Brito, Kwang Sik Kim, Furio Brighenti, Claudio Curti, Cinta Bladé, Josep M Del Bas, Donatella Stilli, Gloria I Solano-Aguilar, Claudia Nunes Dos Santos, Daniele Del Rio, Pedro Mena. 5-(Hydroxyphenyl)-γ-Valerolactone-Sulfate, a Key Microbial Metabolite of Flavan-3-ols, Is Able to Reach the Brain: Evidence from Different in Silico, In Vitro and In Vivo Experimental Models. Nutrients. 2019 Nov; 11(11):. doi: 10.3390/nu11112678. [PMID: 31694297]
  • Javier I Ottaviani, Redmond Fong, Jennifer Kimball, Jodi L Ensunsa, Abigail Britten, Debora Lucarelli, Robert Luben, Philip B Grace, Deborah H Mawson, Amy Tym, Antonia Wierzbicki, Kay-Tee Khaw, Hagen Schroeter, Gunter G C Kuhnle. Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies. Scientific reports. 2018 06; 8(1):9859. doi: 10.1038/s41598-018-28333-w. [PMID: 29959422]
  • Stefanie Wiese, Tuba Esatbeyoglu, Peter Winterhalter, Hans-Peter Kruse, Stephanie Winkler, Achim Bub, Sabine E Kulling. Comparative biokinetics and metabolism of pure monomeric, dimeric, and polymeric flavan-3-ols: a randomized cross-over study in humans. Molecular nutrition & food research. 2015 Apr; 59(4):610-21. doi: 10.1002/mnfr.201400422. [PMID: 25546356]
  • Javier I Ottaviani, Catherine Kwik-Uribe, Carl L Keen, Hagen Schroeter. Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans. The American journal of clinical nutrition. 2012 Apr; 95(4):851-8. doi: 10.3945/ajcn.111.028340. [PMID: 22378733]
  • Fernando Sanchez-Patan, Mourad Chioua, Ignacio Garrido, Carolina Cueva, Abdelouahid Samadi, Jose Marco-Contelles, M Victoria Moreno-Arribas, Begona Bartolome, Maria Monagas. Synthesis, analytical features, and biological relevance of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, a microbial metabolite derived from the catabolism of dietary flavan-3-ols. Journal of agricultural and food chemistry. 2011 Jul; 59(13):7083-91. doi: 10.1021/jf2020182. [PMID: 21627328]
  • Maaike M Appeldoorn, Jean-Paul Vincken, Anna-Marja Aura, Peter C H Hollman, Harry Gruppen. Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-gamma-valerolactone as the major metabolites. Journal of agricultural and food chemistry. 2009 Feb; 57(3):1084-92. doi: 10.1021/jf803059z. [PMID: 19191673]
  • Tomonori Unno, Kimiko Tamemoto, Fumihisa Yayabe, Takami Kakuda. Urinary excretion of 5-(3',4'-dihydroxyphenyl)-gamma-valerolactone, a ring-fission metabolite of (-)-epicatechin, in rats and its in vitro antioxidant activity. Journal of agricultural and food chemistry. 2003 Nov; 51(23):6893-8. doi: 10.1021/jf034578e. [PMID: 14582992]
  • C Li, M J Lee, S Sheng, X Meng, S Prabhu, B Winnik, B Huang, J Y Chung, S Yan, C T Ho, C S Yang. Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea ingestion. Chemical research in toxicology. 2000 Mar; 13(3):177-84. doi: 10.1021/tx9901837. [PMID: 10725114]