L-Glutamic acid 5-benzyl ester (BioDeep_00000177891)

   

human metabolite blood metabolite


代谢物信息卡片


2-amino-5-(benzyloxy)-5-oxopentanoic acid

化学式: C12H15NO4 (237.100103)
中文名称: 聚-L-谷氨酸-γ-苄酯
谱图信息: 最多检出来源 Homo sapiens(blood) 50%

分子结构信息

SMILES: C1=CC=C(C=C1)COC(=O)CCC(C(=O)O)N
InChI: InChI=1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Md Hasan Turabee, Thavasyappan Thambi, Huu Thuy Trang Duong, Ji Hoon Jeong, Doo Sung Lee. A pH- and temperature-responsive bioresorbable injectable hydrogel based on polypeptide block copolymers for the sustained delivery of proteins in vivo. Biomaterials science. 2018 Feb; 6(3):661-671. doi: 10.1039/c7bm00980a. [PMID: 29423489]
  • Shirong Pan, Duanwen Cao, Wu Yi, Huan Huang, Min Feng. A biodegradable and serum-resistant gene delivery carrier composed of polyamidoamine-poly N,N'-di-(2-aminoethyl) aminoethyl glutamine copolymer. Colloids and surfaces. B, Biointerfaces. 2013 Apr; 104(?):294-302. doi: 10.1016/j.colsurfb.2012.12.018. [PMID: 23337121]
  • Ipek Ozcan, Freimar Segura-Sánchez, Kawthar Bouchemal, Murat Sezak, Ozgen Ozer, Tamer Güneri, Gilles Ponchel. Pegylation of poly(γ-benzyl-L-glutamate) nanoparticles is efficient for avoiding mononuclear phagocyte system capture in rats. International journal of nanomedicine. 2010 Dec; 5(?):1103-11. doi: 10.2147/ijn.s15493. [PMID: 21270961]
  • Su Li, Wen-Qi Jiang, An-Xun Wang, Zhong-Zhen Guan, Shi-Rong Pan. [Studies on 5-FU/PEG-PBLG nano-micelles: preparation, characteristics, and drug releasing in vivo]. Ai zheng = Aizheng = Chinese journal of cancer. 2004 Apr; 23(4):381-5. doi: NULL. [PMID: 15087023]
  • K Akamatsu, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida. Development of a hepatocyte-specific prostaglandin E(1) polymeric prodrug and its potential for preventing carbon tetrachloride-induced fulminant hepatitis in mice. The Journal of pharmacology and experimental therapeutics. 1999 Sep; 290(3):1242-9. doi: NULL. [PMID: 10454500]
  • M J Citra, P H Axelsen. Determination of molecular order in supported lipid membranes by internal reflection Fourier transform infrared spectroscopy. Biophysical journal. 1996 Oct; 71(4):1796-805. doi: 10.1016/s0006-3495(96)79380-3. [PMID: 8889156]
  • D J Yang, C Li, S Nikiforow, M B Gretzer, L R Kuang, M S Lopez, K Vargas, S Wallace. Diagnostic and therapeutic potential of poly(benzyl L-glutamate). Journal of pharmaceutical sciences. 1994 Mar; 83(3):328-31. doi: 10.1002/jps.2600830312. [PMID: 7515964]
  • T Chandy, C P Sharma. Effect of plasma glow, glutaraldehyde and carbodiimide treatments on the enzymic degradation of poly (L-lactic acid) and poly (gamma-benzyl-L-glutamate) films. Biomaterials. 1991 Sep; 12(7):677-82. doi: 10.1016/0142-9612(91)90116-r. [PMID: 1720676]
  • I K Kang, Y Ito, M Sisido, Y Imanishi. Adsorption of plasma proteins and platelet adhesion on to polydimethylsiloxane/poly(gamma-benzyl L-glutamate) block copolymer films. Biomaterials. 1988 Mar; 9(2):138-44. doi: 10.1016/0142-9612(88)90112-3. [PMID: 2453225]
  • K Tamura, N Nii, A Suzuki. Effects of pressure and potassium chloride on the aggregation of poly(gamma-benzyl-L-glutamate) in liposomal bilayers. Biophysical chemistry. 1986 Dec; 25(2):169-74. doi: 10.1016/0301-4622(86)87007-7. [PMID: 2434153]