Cinanserin (BioDeep_00000177508)
human metabolite blood metabolite
代谢物信息卡片
N-(2-{[3-(dimethylamino)propyl]sulphanyl}phenyl)-3-phenylprop-2-enimidic acid
化学式: C20H24N2OS (340.1609254)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 66.67%
分子结构信息
SMILES: CN(C)CCCSC1=CC=CC=C1NC(=O)C=CC1=CC=CC=C1
InChI: InChI=1S/C20H24N2OS/c1-22(2)15-8-16-24-19-12-7-6-11-18(19)21-20(23)14-13-17-9-4-3-5-10-17/h3-7,9-14H,8,15-16H2,1-2H3,(H,21,23)
描述信息
同义名列表
5 个代谢物同义名
N-(2-{[3-(dimethylamino)propyl]sulphanyl}phenyl)-3-phenylprop-2-enimidic acid; N-(2-{[3-(dimethylamino)propyl]sulphanyl}phenyl)-3-phenylprop-2-enimidate; N-(2-{[3-(dimethylamino)propyl]sulfanyl}phenyl)-3-phenylprop-2-enimidate; N-(2-{[3-(dimethylamino)propyl]sulfanyl}phenyl)-3-phenylprop-2-enamide; Cinanserin
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ming Hui Chou, Kao Chin Chen, Tzung Lieh Yeh, I Hui Lee, Wei Jen Yao, Po See Chen, Kang-Wei Chang, Mei-Hsiu Liao, Yen Kuang Yang. Association between somatization subscale score and serotonin transporter availability in healthy volunteers--a single photon emission computed tomography study with [¹²³I] ADAM.
Psychopharmacology.
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Psychiatry research.
2011 Dec; 194(3):396-399. doi:
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10.1007/s00213-010-2064-8. [PMID: 21072504] - Fredrik Lindstedt, Jonathan Berrebi, Erik Greayer, Tina B Lonsdorf, Martin Schalling, Martin Ingvar, Eva Kosek. Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene.
PloS one.
2011 Mar; 6(3):e18252. doi:
10.1371/journal.pone.0018252. [PMID: 21464942] - Pei Chun Hsieh, I Hui Lee, Tzung Lieh Yeh, Kao Chin Chen, Hui Chun Huang, Po See Chen, Yen Kuang Yang, Wei Jen Yao, Ru-Band Lu, Nan Tsing Chiu. Distribution volume ratio of serotonin and dopamine transporters in euthymic patients with a history of major depression - a dual-isotope SPECT study.
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2010 Dec; 184(3):157-61. doi:
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2010 Oct; 33(4):393-402. doi:
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European journal of nuclear medicine and molecular imaging.
2010 Aug; 37(8):1507-11. doi:
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Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.
2008 Dec; 66(12):1799-803. doi:
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Computer methods and programs in biomedicine.
2008 Dec; 92(3):294-8. doi:
10.1016/j.cmpb.2008.02.011. [PMID: 18440664] - Jennifer D Lundgren, Andrew B Newberg, Kelly C Allison, Nancy A Wintering, Karl Ploessl, Albert J Stunkard. 123I-ADAM SPECT imaging of serotonin transporter binding in patients with night eating syndrome: a preliminary report.
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2008 Apr; 162(3):214-20. doi:
10.1016/j.pscychresns.2007.07.006. [PMID: 18281200] - Vibe G Frokjaer, Lars H Pinborg, Jacob Madsen, Robin de Nijs, Claus Svarer, Aase Wagner, Gitte M Knudsen. Evaluation of the Serotonin Transporter Ligand 123I-ADAM for SPECT Studies on Humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2008 Feb; 49(2):247-54. doi:
10.2967/jnumed.107.046102. [PMID: 18199621] - Mark Slifstein. Revisiting an old issue: the discrepancy between tissue ratio-derived binding parameters and kinetic modeling-derived parameters after a bolus of the serotonin transporter radioligand 123I-ADAM.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2008 Feb; 49(2):176-8. doi:
10.2967/jnumed.107.046631. [PMID: 18245741] - Walter Koch, Nadine Schaaff, Gabriele Pöpperl, Christoph Mulert, Georg Juckel, Markus Reicherzer, Christoff Ehmer-von Geiso, Hans-Jürgen Möller, Ulrich Hegerl, Klaus Tatsch, Oliver Pogarell. [I-123] ADAM and SPECT in patients with borderline personality disorder and healthy control subjects.
Journal of psychiatry & neuroscience : JPN.
2007 Jul; 32(4):234-40. doi:
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Journal of neurology.
2007 Jun; 254(6):789-96. doi:
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BMC psychiatry.
2007 May; 7(?):19. doi:
10.1186/1471-244x-7-19. [PMID: 17511889] - Yen Kuang Yang, Wei Jen Yao, Tzung Lieh Yeh, I Hui Lee, Kao Ching Chen, Ru Band Lu. Association between serotonin transporter availability and hostility scores in healthy volunteers - a single photon emission computed tomography study with [(123)I] ADAM.
Psychiatry research.
2007 Apr; 154(3):281-4. doi:
10.1016/j.pscychresns.2006.11.010. [PMID: 17349781] - Nikolas Klein, Julia Sacher, Thomas Geiss-Granadia, Nilufar Mossaheb, Trawat Attarbaschi, Rupert Lanzenberger, Christoph Spindelegger, Alexander Holik, Susanne Asenbaum, Robert Dudczak, Johannes Tauscher, Siegfried Kasper. Higher serotonin transporter occupancy after multiple dose administration of escitalopram compared to citalopram: an [123I]ADAM SPECT study.
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2007 Apr; 191(2):333-9. doi:
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2007 Apr; 10(2):211-8. doi:
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2006 Dec; 189(2):145-53. doi:
10.1007/s00213-006-0540-y. [PMID: 17033844] - Ralf Uebelhack, Leonora Franke, Nathalie Herold, Michael Plotkin, Holger Amthauer, Roland Felix. Brain and platelet serotonin transporter in humans-correlation between [123I]-ADAM SPECT and serotonergic measurements in platelets.
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2006 Oct; 406(3):153-8. doi:
10.1016/j.neulet.2006.06.004. [PMID: 16934400] - N Klein, J Sacher, T Geiss-Granadia, T Attarbaschi, N Mossaheb, R Lanzenberger, C Pötzi, A Holik, C Spindelegger, S Asenbaum, R Dudczak, J Tauscher, S Kasper. In vivo imaging of serotonin transporter occupancy by means of SPECT and [123I]ADAM in healthy subjects administered different doses of escitalopram or citalopram.
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2006 Oct; 188(3):263-72. doi:
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2006 May; 113(5):659-70. doi:
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2006 Feb; 33(2):185-91. doi:
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Nuclear medicine and biology.
2006 Feb; 33(2):193-202. doi:
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European journal of nuclear medicine and molecular imaging.
2005 Nov; 32(11):1329-36. doi:
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2005 Aug; 46(8):1301-9. doi:
NULL. [PMID: 16085586] - Andrew B Newberg, Jay D Amsterdam, Nancy Wintering, Karl Ploessl, Randel L Swanson, Justine Shults, Abass Alavi. 123I-ADAM binding to serotonin transporters in patients with major depression and healthy controls: a preliminary study.
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2005 Jun; 46(6):973-7. doi:
NULL. [PMID: 15937308] - Xin-Xian Ye, Jyh-Cheng Chen, Ren-Shen Liu, Shiaw-Pyng Wey, Jin-Shin Lee, Chia-Chieh Chen, Ying-Kai Fu, Gann Ting, Jeng-Jong Hwang. Microautoradiography of [123I]ADAM in mice treated with fluoxetine and serotonin reuptake inhibitors.
Nuclear medicine and biology.
2004 Jul; 31(5):557-62. doi:
10.1016/j.nucmedbio.2003.12.002. [PMID: 15219272] - Andrew B Newberg, Karl Plössl, P David Mozley, James B Stubbs, Nancy Wintering, Michelle Udeshi, Abass Alavi, Tomi Kauppinen, Hank F Kung. Biodistribution and imaging with (123)I-ADAM: a serotonin transporter imaging agent.
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2004 May; 45(5):834-41. doi:
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Nuclear medicine communications.
2004 May; 25(5):515-9. doi:
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Synapse (New York, N.Y.).
2004 May; 52(2):136-42. doi:
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2004 Apr; 45(4):673-81. doi:
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European journal of nuclear medicine and molecular imaging.
2003 Jan; 30(1):132-6. doi:
10.1007/s00259-002-1027-7. [PMID: 12483421] - Kun-Ju Lin, Xin-Xian Ye, Tzu-Chen Yen, Shiaw-Pyng Wey, Kai-Yuan Tzen, Gann Ting, Jeng-Jong Hwang. Biodistribution study of [(123)I] ADAM in mice: correlation with whole body autoradiography.
Nuclear medicine and biology.
2002 Aug; 29(6):643-50. doi:
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2002 Jan; 63(1):135-8. doi:
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