2-(3-(5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one (BioDeep_00000177486)
human metabolite blood metabolite
代谢物信息卡片
化学式: C30H18O10 (538.09)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=C6C(=CC(=CC6=O)O)O5)O)O)O
InChI: InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H
描述信息
同义名列表
3 个代谢物同义名
8-[5-(4,7-dihydroxy-5-oxo-5H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 2-(3-(5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; 8-[5-(4,7-dihydroxy-5-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
---|
文献列表
- O Baâtour, R Kaddour, I Tarchoun, N Nasri, H Mahmoudi, M Zaghdoudi, H Ghaith, B Marzouk, Mouhiba Ben Nasri-Ayachi, M Lachaâl. Modification of fatty acid, essential oil and phenolic contents of salt-treated sweet marjoram (Origanum majorana L.) according to developmental stage.
Journal of food science.
2012 Oct; 77(10):C1047-54. doi:
10.1111/j.1750-3841.2012.02904.x
. [PMID: 22978424] - Ismail O Ishola, Oluwatoyin E Agbaje, T Narender, Olufunmilayo O Adeyemi, Rakesh Shukla. Bioactivity guided isolation of analgesic and anti-inflammatory constituents of Cnestis ferruginea Vahl ex DC (Connaraceae) root.
Journal of ethnopharmacology.
2012 Jul; 142(2):383-9. doi:
10.1016/j.jep.2012.05.004
. [PMID: 22613233] - Loubna Ferchichi, Séverine Derbré, Khalid Mahmood, Kaatio Touré, David Guilet, Marc Litaudon, Khalijah Awang, A Hamid A Hadi, Anne Marie Le Ray, Pascal Richomme. Bioguided fractionation and isolation of natural inhibitors of advanced glycation end-products (AGEs) from Calophyllum flavoramulum.
Phytochemistry.
2012 Jun; 78(?):98-106. doi:
10.1016/j.phytochem.2012.02.006
. [PMID: 22445651] - Yuan Cao, Yongping Wu, Xiaowen Zhou, Fang Qian, Huijia Fan, Qiang Wang. [Simultaneous determination of selaginellins and biflavones in Selaginella tamariscina and S. pulvinata by HPLC].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2012 May; 37(9):1254-8. doi:
. [PMID: 22803371]
- In-Sok Hwang, Juneyoung Lee, Hong-Guang Jin, Eun-Rhan Woo, Dong Gun Lee. Amentoflavone stimulates mitochondrial dysfunction and induces apoptotic cell death in Candida albicans.
Mycopathologia.
2012 Apr; 173(4):207-18. doi:
10.1007/s11046-011-9503-x
. [PMID: 22210020] - K M Sakthivel, C Guruvayoorappan. Biophytum sensitivum: Ancient medicine, modern targets.
Journal of advanced pharmaceutical technology & research.
2012 Apr; 3(2):83-91. doi:
10.4103/2231-4040.97279
. [PMID: 22837955] - Yuelin Song, Yong Jiang, Dan Bi, Xin Tian, Lijuan Liang, Pengfei Tu. [Chemical constituents from n-butanol extract of aerial part of Polygala sibirica].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2012 Feb; 37(4):471-4. doi:
10.4268/cjcmm20120412
. [PMID: 22667146] - Cibele Bonacorsi, Maria Stella G Raddi, Luiz Marcos da Fonseca, Miriam Sannomiya, Wagner Vilegas. Effect of Byrsonima crassa and phenolic constituents on Helicobacter pylori-induced neutrophils oxidative burst.
International journal of molecular sciences.
2012; 13(1):133-41. doi:
10.3390/ijms13010133
. [PMID: 22312243] - Russell L Blaylock, Joseph Maroon. Natural plant products and extracts that reduce immunoexcitotoxicity-associated neurodegeneration and promote repair within the central nervous system.
Surgical neurology international.
2012; 3(?):19. doi:
10.4103/2152-7806.92935
. [PMID: 22439110] - A A Kaikabo, J N Eloff. Antibacterial activity of two biflavonoids from Garcinia livingstonei leaves against Mycobacterium smegmatis.
Journal of ethnopharmacology.
2011 Oct; 138(1):253-5. doi:
10.1016/j.jep.2011.08.023
. [PMID: 21920421] - N Miceli, A Trovato, A Marino, V Bellinghieri, A Melchini, P Dugo, F Cacciola, P Donato, L Mondello, A Güvenç, R De Pasquale, M F Taviano. Phenolic composition and biological activities of Juniperus drupacea Labill. berries from Turkey.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2011 Oct; 49(10):2600-8. doi:
10.1016/j.fct.2011.07.004
. [PMID: 21784120] - U U Nwodo, A A Ngene, C U Iroegbu, O A L Onyedikachi, V N Chigor, A I Okoh. In vivo evaluation of the antiviral activity of Cajanus cajan on measles virus.
Archives of virology.
2011 Sep; 156(9):1551-7. doi:
10.1007/s00705-011-1032-x
. [PMID: 21614435] - Jun-Xia Zheng, Yang Zheng, Hui Zhi, Yi Dai, Nai-Li Wang, Yan-Xiong Fang, Zhi-Yun Du, Kun Zhang, Ming-Ming Li, Li-Ying Wu, Ming Fan. New 3',8''-linked biflavonoids from Selaginella uncinata displaying protective effect against anoxia.
Molecules (Basel, Switzerland).
2011 Jul; 16(8):6206-14. doi:
10.3390/molecules16086206
. [PMID: 21788929] - Shilan Mozaffari, Hadi Esmaily, Roja Rahimi, Maryam Baeeri, Yara Sanei, Azar Asadi-Shahmirzadi, Mohammad-Hossein Salehi-Surmaghi, Mohammad Abdollahi. Effects of Hypericum perforatum extract on rat irritable bowel syndrome.
Pharmacognosy magazine.
2011 Jul; 7(27):213-23. doi:
10.4103/0973-1296.84235
. [PMID: 21969792] - Sojung Lee, Heejong Kim, Jeong-Woo Kang, Jung-Hee Kim, Dong Hun Lee, Man-Sub Kim, Young Yang, Eun-Rhan Woo, Yang Mi Kim, Jintae Hong, Do-Young Yoon. The biflavonoid amentoflavone induces apoptosis via suppressing E7 expression, cell cycle arrest at sub-G₁ phase, and mitochondria-emanated intrinsic pathways in human cervical cancer cells.
Journal of medicinal food.
2011 Jul; 14(7-8):808-16. doi:
10.1089/jmf.2010.1428
. [PMID: 21663495] - Dejan Z Orčić, Neda M Mimica-Dukić, Marina M Francišković, Slobodan S Petrović, Emilija D Jovin. Antioxidant activity relationship of phenolic compounds in Hypericum perforatum L.
Chemistry Central journal.
2011 Jun; 5(?):34. doi:
10.1186/1752-153x-5-34
. [PMID: 21702979] - Valeria Tarallo, Laura Lepore, Marcella Marcellini, Fabrizio Dal Piaz, Laura Tudisco, Salvatore Ponticelli, Frederik Wendelboe Lund, Peter Roepstorff, Augusto Orlandi, Claudio Pisano, Nunziatina De Tommasi, Sandro De Falco. The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors.
The Journal of biological chemistry.
2011 Jun; 286(22):19641-51. doi:
10.1074/jbc.m110.186239
. [PMID: 21471210] - Ilkay Erdogan-Orhan, Mehmet Levent Altun, Betül Sever-Yilmaz, Gülçin Saltan. Anti-acetylcholinesterase and antioxidant assets of the major components (salicin, amentoflavone, and chlorogenic acid) and the extracts of Viburnum opulus and Viburnum lantana and their total phenol and flavonoid contents.
Journal of medicinal food.
2011 Apr; 14(4):434-40. doi:
10.1089/jmf.2010.0053
. [PMID: 21186982] - Elizabeth A Mazzio, Fran Close, Karam F A Soliman. The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.
International journal of molecular sciences.
2011 Jan; 12(1):506-69. doi:
10.3390/ijms12010506
. [PMID: 21340000] - Yuping Zhang, Shuyun Shi, Yuanxi Wang, Kelong Huang. Target-guided isolation and purification of antioxidants from Selaginella sinensis by offline coupling of DPPH-HPLC and HSCCC experiments.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Jan; 879(2):191-6. doi:
10.1016/j.jchromb.2010.12.004
. [PMID: 21183411] - Hans Michler, Gregor Laakmann, Hildebert Wagner. Development of an LC-MS method for simultaneous quantitation of amentoflavone and biapigenin, the minor and major biflavones from Hypericum perforatum L., in human plasma and its application to real blood.
Phytochemical analysis : PCA.
2011 Jan; 22(1):42-50. doi:
10.1002/pca.1249
. [PMID: 20821812] - Kiran S Panickar, Richard A Anderson. Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia.
International journal of molecular sciences.
2011; 12(11):8181-207. doi:
10.3390/ijms12118181
. [PMID: 22174658] - Sang Hoon Jung, Beum Jin Kim, Eun Ha Lee, Neville N Osborne. Isoquercitrin is the most effective antioxidant in the plant Thuja orientalis and able to counteract oxidative-induced damage to a transformed cell line (RGC-5 cells).
Neurochemistry international.
2010 Dec; 57(7):713-21. doi:
10.1016/j.neuint.2010.08.005
. [PMID: 20708054] - Young Bae Ryu, Hyung Jae Jeong, Jang Hoon Kim, Young Min Kim, Ji-Young Park, Doman Kim, Thi Thanh Hanh Nguyen, Su-Jin Park, Jong Sun Chang, Ki Hun Park, Mun-Chual Rho, Woo Song Lee. Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition.
Bioorganic & medicinal chemistry.
2010 Nov; 18(22):7940-7. doi:
10.1016/j.bmc.2010.09.035
. [PMID: 20934345] - Yuchi Zhang, Chunming Liu, Zhengkun Zhang, Jing Wang, Guimei Wu, Sainan Li. Comprehensive separation and identification of chemical constituents from Apocynum venetum leaves by high-performance counter-current chromatography and high performance liquid chromatography coupled with mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Nov; 878(30):3149-55. doi:
10.1016/j.jchromb.2010.09.027
. [PMID: 20965796] - Xianxiao Huang, Wenyuan Gao, Wanshun Zhao, Tiejun Zhang, Jun Xu. [Flavone and steroid chemical constituents from rhizome of Paris axialis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2010 Nov; 35(22):2994-8. doi:
. [PMID: 21355268]
- V Kuete, B Ngameni, A T Mbaveng, B Ngadjui, J J Marion Meyer, N Lall. Evaluation of flavonoids from Dorstenia barteri for their antimycobacterial, antigonorrheal and anti-reverse transcriptase activities.
Acta tropica.
2010 Oct; 116(1):100-4. doi:
10.1016/j.actatropica.2010.06.005
. [PMID: 20599632] - Yuchi Zhang, Chunming Liu, Zhengkun Zhang, Yanjuan Qi, Guimei Wu, Sainan Li. Solvent gradient elution for comprehensive separation of constituents with wide range of polarity in Apocynum venetum leaves by high-speed counter-current chromatography.
Journal of separation science.
2010 Sep; 33(17-18):2743-8. doi:
10.1002/jssc.201000308
. [PMID: 20730835] - Tamara R Calvo, Diego Demarco, Fabio V Santos, Helen P Moraes, Taís M Bauab, Eliana A Varanda, Ilce M S Cólus, Wagner Vilegas. Phenolic compounds in leaves of Alchornea triplinervia: anatomical localization, mutagenicity, and antibacterial activity.
Natural product communications.
2010 Aug; 5(8):1225-32. doi:
. [PMID: 20839624]
- Weihuan Huang, Xiaoli Zhang, Yifei Wang, Wencai Ye, Vincent Ec Ooi, Hau Yin Chung, Yaolan Li. Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen).
Chinese medicine.
2010 Jun; 5(?):23. doi:
10.1186/1749-8546-5-23
. [PMID: 20565950] - Song Gao, Wen Jiang, Taijun Yin, Ming Hu. Highly variable contents of phenolics in St. John's Wort products affect their transport in the human intestinal Caco-2 cell model: pharmaceutical and biopharmaceutical rationale for product standardization.
Journal of agricultural and food chemistry.
2010 Jun; 58(11):6650-9. doi:
10.1021/jf904459u
. [PMID: 20450158] - Cüneyt Cirak, Jolita Radusiene, Valdimaras Janulis, Liudas Ivanauskas. Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance.
Natural product communications.
2010 Jun; 5(6):897-8. doi:
"
. [PMID: 20614818] - Junxian Wang, Yuanyuan Zhang, Sheng Chen, Min Zhao, Lu Zhang. [Chemical constituents of Discocleidion rufescens].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2010 Jun; 35(11):1435-8. doi:
. [PMID: 20822016]
- Ali Ozmen, Sabine Bauer, Manuela Gridling, Judith Singhuber, Stanimira Krasteva, Sibylle Madlener, Than Phuong Nha Vo, Nicole Stark, Philipp Saiko, Monika Fritzer-Szekeres, Thomas Szekeres, Tülay Askin-Celik, Liselotte Krenn, Georg Krupitza. In vitro anti-neoplastic activity of the ethno-pharmaceutical plant Hypericum adenotrichum Spach endemic to Western Turkey.
Oncology reports.
2009 Oct; 22(4):845-52. doi:
10.3892/or_00000508
. [PMID: 19724864] - Adamu A Kaikabo, Babatunde B Samuel, Jacobus N Eloff. Isolation and activity of two antibacterial biflavonoids from leaf extracts of Garcinia livingstonei (Clusiaceae).
Natural product communications.
2009 Oct; 4(10):1363-6. doi:
NULL
. [PMID: 19911572] - Cibele Bonacorsi, Maria Stella G Raddi, Iracilda Z Carlos, Miriam Sannomiya, Wagner Vilegas. Anti-Helicobacter pylori activity and immunostimulatory effect of extracts from Byrsonima crassa Nied. (Malpighiaceae).
BMC complementary and alternative medicine.
2009 Jan; 9(?):2. doi:
10.1186/1472-6882-9-2
. [PMID: 19149866] - Wen-Jie Tan, Jia-Cheng Xu, Li Li, Ke-Li Chen. Bioactive compounds of inhibiting xanthine oxidase from Selaginella labordei.
Natural product research.
2009; 23(4):393-8. doi:
10.1080/14786410802228736
. [PMID: 19296380] - Cüneyt Cirak, Liudas Ivanauskas, Valdimaras Janulis, Jolita Radusiene. Chemical constituents of Hypericum adenotrichum Spach, an endemic Turkish species.
Natural product research.
2009; 23(13):1189-95. doi:
10.1080/14786410802393209
. [PMID: 19731137] - Tom Erik Grønhaug, Silje Glaeserud, Mona Skogsrud, Ngolo Ballo, Sekou Bah, Drissa Diallo, Berit Smestad Paulsen. Ethnopharmacological survey of six medicinal plants from Mali, West-Africa.
Journal of ethnobiology and ethnomedicine.
2008 Dec; 4(?):26. doi:
10.1186/1746-4269-4-26
. [PMID: 19111068] - Gary I Stafford, Mikael E Pedersen, Johannes van Staden, Anna K Jäger. Review on plants with CNS-effects used in traditional South African medicine against mental diseases.
Journal of ethnopharmacology.
2008 Oct; 119(3):513-37. doi:
10.1016/j.jep.2008.08.010
. [PMID: 18775771] - Adonis Bello Alarcón, Osmany Cuesta-Rubio, Jorge Cárdenas Pérez, Anna Lisa Piccinelli, Luca Rastrelli. Constituents of the Cuban endemic species Calophyllum pinetorum.
Journal of natural products.
2008 Jul; 71(7):1283-6. doi:
10.1021/np800079c
. [PMID: 18553925] - Milena Colovic, Claudia Fracasso, Silvio Caccia. Brain-to-plasma distribution ratio of the biflavone amentoflavone in the mouse.
Drug metabolism letters.
2008 Apr; 2(2):90-4. doi:
10.2174/187231208784040988
. [PMID: 19356077] - Armelle Tsafack Mbaveng, Bathélémy Ngameni, Victor Kuete, Ingrid Konga Simo, Pantaléon Ambassa, René Roy, Merhatibeb Bezabih, François-Xavier Etoa, Bonaventure Tchaleu Ngadjui, Berhanu M Abegaz, J J Marion Meyer, Namrita Lall, Véronique Penlap Beng. Antimicrobial activity of the crude extracts and five flavonoids from the twigs of Dorstenia barteri (Moraceae).
Journal of ethnopharmacology.
2008 Mar; 116(3):483-9. doi:
10.1016/j.jep.2007.12.017
. [PMID: 18280679] - Walclecio de Moraes Lira, Fabio Vieira dos Santos, Miriam Sannomiya, Clenilson Martins Rodrigues, Wagner Vilegas, Eliana Aparecida Varanda. Modulatory effect of Byrsonima basiloba extracts on the mutagenicity of certain direct and indirect-acting mutagens in Salmonella typhimurium assays.
Journal of medicinal food.
2008 Mar; 11(1):111-9. doi:
10.1089/jmf.2007.553
. [PMID: 18361746] - Sloan Ayers, Deborah L Zink, Kenneth Mohn, Joanne S Powell, Christine M Brown, Terry Murphy, Robert Brand, Seef Pretorius, Dennis Stevenson, Donald Thompson, Sheo B Singh. Flavones from Struthiola argentea with anthelmintic activity in vitro.
Phytochemistry.
2008 Jan; 69(2):541-5. doi:
10.1016/j.phytochem.2007.08.003
. [PMID: 17923139] - Hyun Jun Jung, Keunnam Park, In-Seon Lee, Hyun Soo Kim, Soo-Hwan Yeo, Eun-Rhan Woo, Dong Gun Lee. S-phase accumulation of Candida albicans by anticandidal effect of amentoflavone isolated from Selaginella tamariscina.
Biological & pharmaceutical bulletin.
2007 Oct; 30(10):1969-71. doi:
10.1248/bpb.30.1969
. [PMID: 17917274] - Mehdi Chaabi, Cyril Antheaume, Bernard Weniger, Hélène Justiniano, Claire Lugnier, Annelise Lobstein. Biflavones of Decussocarpus rospigliosii as phosphodiesterases inhibitors.
Planta medica.
2007 Oct; 73(12):1284-6. doi:
10.1055/s-2007-990218
. [PMID: 17893835] - Daniela Fritz, Caroline Rita Venturi, Simone Cargnin, Jan Schripsema, Paulo Michel Roehe, Jarbas Alves Montanha, Gilsane Lino von Poser. Herpes virus inhibitory substances from Hypericum connatum Lam., a plant used in southern Brazil to treat oral lesions.
Journal of ethnopharmacology.
2007 Sep; 113(3):517-20. doi:
10.1016/j.jep.2007.07.013
. [PMID: 17719731] - Kimberly D P Hammer, Matthew L Hillwig, Avery K S Solco, Philip M Dixon, Kathleen Delate, Patricia A Murphy, Eve S Wurtele, Diane F Birt. Inhibition of prostaglandin E(2) production by anti-inflammatory hypericum perforatum extracts and constituents in RAW264.7 Mouse Macrophage Cells.
Journal of agricultural and food chemistry.
2007 Sep; 55(18):7323-31. doi:
10.1021/jf0710074
. [PMID: 17696442] - Nabaweya Ali Ibrahim, Hesham Rushdey El-Seedi, Magdy Mostafa Desoky Mohammed. Phytochemical investigation and hepatoprotective activity of Cupressus sempervirens L. leaves growing in Egypt.
Natural product research.
2007 Aug; 21(10):857-66. doi:
10.1080/14786410601132477
. [PMID: 17680494] - Nzi André Konan, Elfriede Marianne Bacchi. Antiulcerogenic effect and acute toxicity of a hydroethanolic extract from the cashew (Anacardium occidentale L.) leaves.
Journal of ethnopharmacology.
2007 Jun; 112(2):237-42. doi:
10.1016/j.jep.2007.03.003
. [PMID: 17499463] - Miriam Sannomiya, Cássia R P Cardoso, Maria E Figueiredo, Clenilson M Rodrigues, Lourdes C dos Santos, Fabio V dos Santos, Juliana M Serpeloni, Ilce M S Cólus, Wagner Vilegas, Eliana A Varanda. Mutagenic evaluation and chemical investigation of Byrsonima intermedia A. Juss. leaf extracts.
Journal of ethnopharmacology.
2007 Jun; 112(2):319-26. doi:
10.1016/j.jep.2007.03.014
. [PMID: 17459621] - C Guruvayoorappan, Girija Kuttan. Effect of amentoflavone on the inhibition of pulmonary metastasis induced by B16F-10 melanoma cells in C57BL/6 mice.
Integrative cancer therapies.
2007 Jun; 6(2):185-97. doi:
10.1177/1534735407302345
. [PMID: 17548797] - Silvio Sosa, Roberto Pace, Anna Bornancin, Paolo Morazzoni, Antonella Riva, Aurelia Tubaro, Roberto Della Loggia. Topical anti-inflammatory activity of extracts and compounds from Hypericum perforatum L.
The Journal of pharmacy and pharmacology.
2007 May; 59(5):703-9. doi:
10.1211/jpp.59.5.0011
. [PMID: 17524236] - Yan-zhi Li, Zhan-lin Li, Hui-ming Hua, Zheng-gang Li, Ming-sheng Liu. [Studies on flavonoids from stems and leaves of Calophyllum inophyllum].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2007 Apr; 32(8):692-4. doi:
. [PMID: 17608221]
- Tamara Regina Calvo, Zeila Pinheiro Lima, Janaina Scaramelo Silva, Kátia Vero Nica Rodrigues Ballesteros, Cláudia Helena Pellizzon, Clélia Akiko Hiruma-Lima, Jorge Tamashiro, Alba Regina Monteiro Souza Brito, Regina Kiomi Takahira, Wagner Vilegas. Constituents and antiulcer effect of Alchornea glandulosa: activation of cell proliferation in gastric mucosa during the healing process.
Biological & pharmaceutical bulletin.
2007 Mar; 30(3):451-9. doi:
10.1248/bpb.30.451
. [PMID: 17329837] - Chandrasekharan Guruvayoorappan, Girija Kuttan. Amentoflavone, a biflavonoid from Biophytum sensitivum augments lymphocyte proliferation, natural killer cell and antibody dependent cellular cytotoxicity through enhanced production of IL-2 and IFN-gamma and restrains serum sialic acid and gamma glutamyl transpeptidase production in tumor - bearing animals.
Journal of experimental therapeutics & oncology.
2007; 6(4):285-95. doi:
. [PMID: 18038762]
- A G B Azebaze, A B Dongmo, M Meyer, B M W Ouahouo, A Valentin, E Laure Nguemfo, A E Nkengfack, W Vierling. Antimalarial and vasorelaxant constituents of the leaves of Allanblackia monticola (Guttiferae).
Annals of tropical medicine and parasitology.
2007 Jan; 101(1):23-30. doi:
10.1179/136485907x157022
. [PMID: 17244407] - Oliver Grundmann, Olaf Kelber, Veronika Butterweck. Effects of St. John's wort extract and single constituents on stress-induced hyperthermia in mice.
Planta medica.
2006 Dec; 72(15):1366-71. doi:
10.1055/s-2006-951710
. [PMID: 17051457] - Sook Kyung Hyun, Hyun Ah Jung, Hae Young Chung, Jae Sue Choi. In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves.
Archives of pharmacal research.
2006 Dec; 29(12):1074-9. doi:
10.1007/bf02969294
. [PMID: 17225453] - Hyun Jun Jung, Woo Sang Sung, Soo-Hwan Yeo, Hyun Soo Kim, In-Seon Lee, Eun-Rhan Woo, Dong Gun Lee. Antifungal effect of amentoflavone derived from Selaginella tamariscina.
Archives of pharmacal research.
2006 Sep; 29(9):746-51. doi:
10.1007/bf02974074
. [PMID: 17024847] - Cássia Regina Primila Cardoso, Ilce Mara de Syllos Cólus, Caroline Cristiane Bernardi, Miriam Sannomiya, Wagner Vilegas, Eliana Aparecida Varanda. Mutagenic activity promoted by amentoflavone and methanolic extract of Byrsonima crassa Niedenzu.
Toxicology.
2006 Aug; 225(1):55-63. doi:
10.1016/j.tox.2006.05.003
. [PMID: 16781041] - Yan-hua Lu, Zhi-yong Liu, Zheng-tao Wang, Dong-zhi Wei. Quality evaluation of Platycladus orientalis (L.) Franco through simultaneous determination of four bioactive flavonoids by high-performance liquid chromatography.
Journal of pharmaceutical and biomedical analysis.
2006 Jun; 41(4):1186-90. doi:
10.1016/j.jpba.2006.02.054
. [PMID: 16621407] - S M Sagar, D Yance, R K Wong. Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 2.
Current oncology (Toronto, Ont.).
2006 Jun; 13(3):99-107. doi:
"
. [PMID: 17576449] - Felicia B Williams, Lane C Sander, Stephen A Wise, James Girard. Development and evaluation of methods for determination of naphthodianthrones and flavonoids in St. John's wort.
Journal of chromatography. A.
2006 May; 1115(1-2):93-102. doi:
10.1016/j.chroma.2006.02.078
. [PMID: 16554056] - Mario Dell'Agli, Germana V Galli, Enrica Bosisio. Inhibition of cGMP-phosphodiesterase-5 by biflavones of Ginkgo biloba.
Planta medica.
2006 Apr; 72(5):468-70. doi:
10.1055/s-2005-916236
. [PMID: 16557462] - Ramalla Chidananda Swamy, Olaf Kunert, Wolfgang Schühly, Franz Bucar, Daneel Ferreira, Vanapatla Swarupa Rani, Bobbala Ravi Kumar, Achanta Venkata Narasimha Appa Rao. Structurally unique biflavonoids from Selaginella chrysocaulos and Selaginella bryopteris.
Chemistry & biodiversity.
2006 Apr; 3(4):405-13. doi:
10.1002/cbdv.200690044
. [PMID: 17193277] - David J Greenblatt, Lisa L von Moltke, Yan Luo, Elke S Perloff, Kelly A Horan, Allison Bruce, Robyn C Reynolds, Jerold S Harmatz, Bharathi Avula, Ikhlas A Khan, Peter Goldman. Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate.
Journal of clinical pharmacology.
2006 Feb; 46(2):214-21. doi:
10.1177/0091270005283465
. [PMID: 16432273] - Ann Bygvraa Svenningsen, Katrine Damkjaer Madsen, Tommy Liljefors, Gary I Stafford, Johannes van Staden, Anna K Jäger. Biflavones from Rhus species with affinity for the GABA(A)/benzodiazepine receptor.
Journal of ethnopharmacology.
2006 Jan; 103(2):276-80. doi:
10.1016/j.jep.2005.08.012
. [PMID: 16168585] - Mikiko Ito, Sakiko Haito, Mari Furumoto, Yoshichika Kawai, Junji Terao, Ken-ichi Miyamoto. Approach to novel functional foods for stress control 4. Regulation of serotonin transporter by food factors.
The journal of medical investigation : JMI.
2005 Nov; 52 Suppl(?):245-8. doi:
10.2152/jmi.52.245
. [PMID: 16366509] - Joo-Heon Yoon, Seung Joon Baek. Molecular targets of dietary polyphenols with anti-inflammatory properties.
Yonsei medical journal.
2005 Oct; 46(5):585-96. doi:
10.3349/ymj.2005.46.5.585
. [PMID: 16259055] - Xulin Pan, Ninghua Tan, Guangzhi Zeng, Yumei Zhang, Ruirui Jia. Amentoflavone and its derivatives as novel natural inhibitors of human Cathepsin B.
Bioorganic & medicinal chemistry.
2005 Oct; 13(20):5819-25. doi:
10.1016/j.bmc.2005.05.071
. [PMID: 16084098] - Mirosława Krauze-Baranowska, Loretta Pobłocka, Atef Ahmed El-Hela. Biflavones from Chamaecyparis obtusa.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2005 Sep; 60(9-10):679-85. doi:
10.1515/znc-2005-9-1004
. [PMID: 16320608] - Lydia F Yamaguchi, Daniel G Vassão, Massuo J Kato, Paolo Di Mascio. Biflavonoids from Brazilian pine Araucaria angustifolia as potentials protective agents against DNA damage and lipoperoxidation.
Phytochemistry.
2005 Sep; 66(18):2238-47. doi:
10.1016/j.phytochem.2004.11.014
. [PMID: 16153416] - Dieudonné Emmanuel Pegnyemb, Josephine Ngo Mbing, Alex de Théodore Atchadé, Raphael Ghogomu Tih, Beiban Lucas Sondengam, Alain Blond, Bernard Bodo. Antimicrobial biflavonoids from the aerial parts of Ouratea sulcata.
Phytochemistry.
2005 Aug; 66(16):1922-6. doi:
10.1016/j.phytochem.2005.06.017
. [PMID: 16083925] - E R Woo, J Y Lee, I J Cho, S G Kim, K W Kang. Amentoflavone inhibits the induction of nitric oxide synthase by inhibiting NF-kappaB activation in macrophages.
Pharmacological research.
2005 Jun; 51(6):539-46. doi:
10.1016/j.phrs.2005.02.002
. [PMID: 15829434] - Renato Bruni, Federica Pellati, Maria Grazia Bellardi, Stefania Benvenuti, Samanta Paltrinieri, Assunta Bertaccini, Alberto Bianchi. Herbal drug quality and phytochemical composition of Hypericum perforatum L. affected by ash yellows phytoplasma infection.
Journal of agricultural and food chemistry.
2005 Feb; 53(4):964-8. doi:
10.1021/jf0487654
. [PMID: 15713006] - Miriam Sannomiya, Paola Montoro, Sonia Piacente, Cosimo Pizza, Alba R M S Brito, Wagner Vilegas. Application of liquid chromatography/electrospray ionization tandem mass spectrometry to the analysis of polyphenolic compounds from an infusion of Byrsonima crassa Niedenzu.
Rapid communications in mass spectrometry : RCM.
2005; 19(16):2244-50. doi:
10.1002/rcm.2053
. [PMID: 16015675] - Maira Huerta-Reyes, Maria Del Carmen Basualdo, Fumiko Abe, Manuel Jimenez-Estrada, Carmen Soler, Ricardo Reyes-Chilpa. HIV-1 inhibitory compounds from Calophyllum brasiliense leaves.
Biological & pharmaceutical bulletin.
2004 Sep; 27(9):1471-5. doi:
10.1248/bpb.27.1471
. [PMID: 15340243] - Ricardo Reyes-Chilpa, Elizabet Estrada-Muñiz, Teresa Ramírez Apan, Badia Amekraz, Andre Aumelas, Christopher K Jankowski, Mario Vázquez-Torres. Cytotoxic effects of mammea type coumarins from Calophyllum brasiliense.
Life sciences.
2004 Aug; 75(13):1635-47. doi:
10.1016/j.lfs.2004.03.017
. [PMID: 15261767] - Dae Gill Kang, Ming Hao Yin, Hyuncheol Oh, Dae Ho Lee, Ho Sub Lee. Vasorelaxation by amentoflavone isolated from Selaginella tamariscina.
Planta medica.
2004 Aug; 70(8):718-22. doi:
10.1055/s-2004-827201
. [PMID: 15326548] - Lisa L von Moltke, James L Weemhoff, Erdal Bedir, Ikhlas A Khan, Jerold S Harmatz, Peter Goldman, David J Greenblatt. Inhibition of human cytochromes P450 by components of Ginkgo biloba.
The Journal of pharmacy and pharmacology.
2004 Aug; 56(8):1039-44. doi:
10.1211/0022357044021
. [PMID: 15285849] - Shih-Chang Chien, Han-Kang Liu, Yueh-Hsiung Kuo. Two new compounds from the leaves of Calocedrus microlepic var. formosana.
Chemical & pharmaceutical bulletin.
2004 Jun; 52(6):762-3. doi:
10.1248/cpb.52.762
. [PMID: 15187403] - Fumiko Abe, Shinya Nagafuji, Hikaru Okabe, Hiroshige Akahane, Elizabeth Estrada-Muñiz, Maira Huerta-Reyes, Ricardo Reyes-Chilpa. Trypanocidal constituents in plants 3. Leaves of Garcinia intermedia and heartwood of Calophyllum brasiliense.
Biological & pharmaceutical bulletin.
2004 Jan; 27(1):141-3. doi:
10.1248/bpb.27.141
. [PMID: 14709920] - Ben Seaver, Jerry Robert Smith. Inhibition of COX isoforms by nutraceuticals.
Journal of herbal pharmacotherapy.
2004; 4(2):11-8. doi:
. [PMID: 15364641]
- Ling-Yun Ma, Shuang-Cheng Ma, Feng Wei, Rui-Chao Lin, Paul Pui-Hay But, Spencer Hon-Sun Lee, Song Fong Lee. Uncinoside A and B, two new antiviral chromone glycosides from Selaginella uncinata.
Chemical & pharmaceutical bulletin.
2003 Nov; 51(11):1264-7. doi:
10.1248/cpb.51.1264
. [PMID: 14600370] - Jane R Hanrahan, Mary Chebib, Neil L M Davucheron, Belinda J Hall, Graham A R Johnston. Semisynthetic preparation of amentoflavone: A negative modulator at GABA(A) receptors.
Bioorganic & medicinal chemistry letters.
2003 Jul; 13(14):2281-4. doi:
10.1016/s0960-894x(03)00434-7
. [PMID: 12824018] - Sheng-Hong Li, Hong-Jie Zhang, Xue-Mei Niu, Ping Yao, Han-Dong Sun, Harry H S Fong. Chemical constituents from Amentotaxus yunnanensis and Torreyayunnanensis.
Journal of natural products.
2003 Jul; 66(7):1002-5. doi:
10.1021/np030117b
. [PMID: 12880325] - Mirosława Krauze-Baranowska, Marek Mardarowicz, Marian Wiwart. The chemical composition of Microbiota decussata.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2002 Nov; 57(11-12):998-1003. doi:
10.1515/znc-2002-11-1208
. [PMID: 12562084] - Tsutomu Nakanishi, Yuka Inatomi, Hiroko Murata, Naoki Iida, Akira Inada, Frank A Lang, Jin Murata. Phytochemical study on American plants I. Two new phenol glucosides, together with known biflavones and diterpene, from leaves of Juniperus occidentalis Hook.
Chemical & pharmaceutical bulletin.
2002 Oct; 50(10):1358-61. doi:
10.1248/cpb.50.1358
. [PMID: 12372862] - H Gutmann, R Bruggisser, W Schaffner, K Bogman, A Botomino, J Drewe. Transport of amentoflavone across the blood-brain barrier in vitro.
Planta medica.
2002 Sep; 68(9):804-7. doi:
10.1055/s-2002-34401
. [PMID: 12357391] - Javier Rincon Velandia, Mário Geraldo de Carvalho, Raimundo Braz-Filho, Alceni A Werle. Biflavonoids and a glucopyranoside derivative from Ouratea semiserrata.
Phytochemical analysis : PCA.
2002 Sep; 13(5):283-92. doi:
10.1002/pca.656
. [PMID: 12918874] - T Banerjee, A Van der Vliet, V A Ziboh. Downregulation of COX-2 and iNOS by amentoflavone and quercetin in A549 human lung adenocarcinoma cell line.
Prostaglandins, leukotrienes, and essential fatty acids.
2002 May; 66(5-6):485-92. doi:
10.1054/plef.2002.0387
. [PMID: 12144868] - Mario Dell'Agli, Enrica Bosisio. Biflavones of Ginkgo biloba stimulate lipolysis in 3T3-L1 adipocytes.
Planta medica.
2002 Jan; 68(1):76-9. doi:
10.1055/s-2002-19876
. [PMID: 11842336] - M Y Rios, A González-Morales, M L Villarreal. Sterols, triterpenes and biflavonoids of Viburnum jucundum and cytotoxic activity of ursolic acid.
Planta medica.
2001 Oct; 67(7):683-4. doi:
10.1055/s-2001-17357
. [PMID: 11582553] - K L da Silva, A R dos Santos, P E Mattos, R A Yunes, F Delle-Monache, V Cechinel-Filho. Chemical composition and analgesic activity of Calophyllum brasiliense leaves.
Therapie.
2001 Jul; 56(4):431-4. doi:
"
. [PMID: 11677868]