3-Benzyl-5-(6-carboxyhexyl)-1-(2-cyclohexyl-2-hydroxyethylamino)hydantoin (BioDeep_00000176906)

   

human metabolite blood metabolite


代谢物信息卡片


7-{1-benzyl-3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxoimidazolidin-4-yl}heptanoic acid

化学式: C25H37N3O5 (459.27330720000003)
中文名称: 3-[(2-环己基-2-羟乙基)氨基]-2,5-二氧代-1-(苯甲基)-4-咪唑啶庚酸
谱图信息: 最多检出来源 Homo sapiens(blood) 28.57%

分子结构信息

SMILES: C1CCC(CC1)C(CNN2C(C(=O)N(C2=O)CC3=CC=CC=C3)CCCCCCC(=O)O)O
InChI: InChI=1S/C25H37N3O5/c29-22(20-13-7-4-8-14-20)17-26-28-21(15-9-1-2-10-16-23(30)31)24(32)27(25(28)33)18-19-11-5-3-6-12-19/h3,5-6,11-12,20-22,26,29H,1-2,4,7-10,13-18H2,(H,30,31)

描述信息

D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors

同义名列表

9 个代谢物同义名

7-{1-benzyl-3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxoimidazolidin-4-yl}heptanoic acid; 7-{1-benzyl-3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxoimidazolidin-4-yl}heptanoate; 3-Benzyl-5-(6-carboxyhexyl)-1-(2-cyclohexyl-2-hydroxyethylamino)hydantoin; BW-a-868C; BW a 868C; BW-a868c; BW A868C; BWA868c; BW 868C



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Natália R T Amorim, Tatiana Luna-Gomes, Marcos Gama-Almeida, Glaucia Souza-Almeida, Claudio Canetti, Bruno L Diaz, Peter F Weller, Patricia Torres Bozza, Clarissa M Maya-Monteiro, Christianne Bandeira-Melo. Leptin Elicits LTC4 Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD2 Receptors. Frontiers in immunology. 2018; 9(?):2139. doi: 10.3389/fimmu.2018.02139. [PMID: 30298073]
  • Chihiro Miyamoto, Mariko Yoshida, Masaaki Yoshikawa, Takafumi Mizushige, Kousaku Ohinata. Complement C5a exhibits anxiolytic-like activity via the prostaglandin D2-DP1 receptor system coupled to adenosine A2A and GABAA receptors. Prostaglandins & other lipid mediators. 2012 May; 98(1-2):17-22. doi: 10.1016/j.prostaglandins.2012.03.004. [PMID: 22503964]
  • Kousaku Ohinata, Kuniko Takagi, Kyoko Biyajima, Kentaro Kaneko, Chihiro Miyamoto, Akihiro Asakawa, Naomi Eguchi, Yoshihiro Urade, Akio Inui, Masaaki Yoshikawa. Complement C5a stimulates food intake via a prostaglandin D(2)- and neuropeptide Y-dependent mechanism in mice. Prostaglandins & other lipid mediators. 2009 Dec; 90(3-4):81-4. doi: 10.1016/j.prostaglandins.2009.09.001. [PMID: 19800413]
  • Hui Zhao, Kousaku Ohinata, Masaaki Yoshikawa. Central prostaglandin D(2) exhibits anxiolytic-like activity via the DP(1) receptor in mice. Prostaglandins & other lipid mediators. 2009 Apr; 88(3-4):68-72. doi: 10.1016/j.prostaglandins.2008.10.001. [PMID: 19007903]
  • Rufina Schuligoi, Miriam Sedej, Maria Waldhoer, Anela Vukoja, Eva M Sturm, Irmgard T Lippe, Bernhard A Peskar, Akos Heinemann. Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2. Journal of leukocyte biology. 2009 Jan; 85(1):136-45. doi: 10.1189/jlb.0608387. [PMID: 18835884]
  • Md Ashequr Rahman, Toshio Inoue, Takashi Ishikawa, Rie Yatsuzuka, Hiroshi Ohtsu, Chiaki Kamei. Involvement of chemical mediators in nasal allergic responses of HDC-KO mice. European journal of pharmacology. 2007 Jul; 567(3):245-51. doi: 10.1016/j.ejphar.2007.01.082. [PMID: 17543300]
  • D H Wright, K M Metters, M Abramovitz, A W Ford-Hutchinson. Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist. British journal of pharmacology. 1998 Apr; 123(7):1317-24. doi: 10.1038/sj.bjp.0701708. [PMID: 9579725]
  • D F Woodward, C S Spada, S B Hawley, L S Williams, C E Protzman, A L Nieves. Further studies on ocular responses to DP receptor stimulation. European journal of pharmacology. 1993 Jan; 230(3):327-33. doi: 10.1016/0014-2999(93)90569-4. [PMID: 8440310]
  • Y Naito, J Fukata, K Shindo, O Ebisui, N Murakami, T Tominaga, Y Nakai, K Mori, N W Kasting, H Imura. Effects of interleukins on plasma arginine vasopressin and oxytocin levels in conscious, freely moving rats. Biochemical and biophysical research communications. 1991 Feb; 174(3):1189-95. doi: 10.1016/0006-291x(91)91547-p. [PMID: 1671747]