Pentadecanol (BioDeep_00000017686)

 

Secondary id: BioDeep_00000863564

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


InChI=1/C15H32O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16/h16H,2-15H2,1H

化学式: C15H32O (228.2453022)
中文名称: 十五烷醇
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 0.88%

分子结构信息

SMILES: CCCCCCCCCCCCCCCO
InChI: InChI=1S/C15H32O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16/h16H,2-15H2,1H3

描述信息

Pentadecanol is a C-15 fatty alcohol. Very long chain fatty alcohols (VLCFA), obtained from plant waxes and beeswax have been reported to lower plasma cholesterol in humans. They can be found in unrefined cereal grains, beeswax, and many plant-derived foods. Reports suggest that 5–20 mg per day of mixed C24–C34 alcohols, including octacosanol and triacontanol, lower low-density lipoprotein (LDL) cholesterol by 21\\\\%–29\\\\% and raise high-density lipoprotein cholesterol by 8\\\\%–15\\\\%. Wax esters are hydrolyzed by a bile salt-dependent pancreatic carboxyl esterase, releasing long chain alcohols and fatty acids that are absorbed in the gastrointestinal tract. Studies of fatty alcohol metabolism in fibroblasts suggest that very long chain fatty alcohols, fatty aldehydes, and fatty acids are reversibly inter-converted in a fatty alcohol cycle. The metabolism of these compounds is impaired in several inherited human peroxisomal disorders, including adrenoleukodystrophy and Sjögren-Larsson syndrome.
Pentadecanol is a colorless liquid with a faint odor of alcohol. Floats on water. (USCG, 1999)
Pentadecan-1-ol is a long-chain fatty alcohol that is pentadecane in which one of the terminal methyl hydrogens is replaced by a hydroxy group It is a long-chain primary fatty alcohol and a pentadecanol.
1-Pentadecanol is a natural product found in Curcuma amada, Cichorium endivia, and other organisms with data available.
A long-chain fatty alcohol that is pentadecane in which one of the terminal methyl hydrogens is replaced by a hydroxy group
Pentadecanol is a C-15 fatty alcohol
1-Pentadecanol is a naturally occurring antiacne agent[1].
1-Pentadecanol is a naturally occurring antiacne agent[1].

同义名列表

20 个代谢物同义名

InChI=1/C15H32O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16/h16H,2-15H2,1H; Pentadecanol,95\\%; n-Pentadecyl alcohol; 1-pentadecanol (ACD/Name 4.0); PENTADECYL ALCOHOL [INCI]; 1-Pentadecanol, 99\\%; n-pentadecyl alcohol; Pentadecyl alcohol; n-1-Pentadecanol; Pentadecanol-(1); pentadecan-1-ol; n-pPentadecanol; n-Pentadecanol; 1-Pentadecanol; Tox21_300553; Pentadecanol; Tox21_201699; AI3-33881; FOH 15:0; Neodol 5; Alfol 15



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

19 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Janine Hellenbrand, Eva-Maria Biester, Jens Gruber, Mats Hamberg, Margrit Frentzen. Fatty acyl-CoA reductases of birds. BMC biochemistry. 2011 Dec; 12(?):64. doi: 10.1186/1471-2091-12-64. [PMID: 22151413]
  • Frédéric Domergue, Sollapura J Vishwanath, Jérôme Joubès, Jasmine Ono, Jennifer A Lee, Matthieu Bourdon, Reem Alhattab, Christine Lowe, Stéphanie Pascal, René Lessire, Owen Rowland. Three Arabidopsis fatty acyl-coenzyme A reductases, FAR1, FAR4, and FAR5, generate primary fatty alcohols associated with suberin deposition. Plant physiology. 2010 Aug; 153(4):1539-54. doi: 10.1104/pp.110.158238. [PMID: 20571114]
  • Igor Jerković, Zvonimir Marijanović, I Ljubicić, M Gugić. Contribution of the bees and combs to honey volatiles: blank-trial probe for chemical profiling of honey biodiversity. Chemistry & biodiversity. 2010 May; 7(5):1217-30. doi: 10.1002/cbdv.200900100. [PMID: 20491078]
  • K Udeni Alwis, Lennart Larsson, Donald K Milton. Suppression of ionization and optimization of assay for 3-hydroxy fatty acids in house dust using ion-trap mass spectrometry. American journal of industrial medicine. 2006 Apr; 49(4):286-95. doi: 10.1002/ajim.20263. [PMID: 16550567]