Systemin (BioDeep_00000017673)
human metabolite PANOMIX_OTCML-2023 Endogenous
代谢物信息卡片
(3S)-4-[(2S)-1-[(2S)-1-[(2S)-2-{[(2S)-2-{[(2S)-6-amino-2-{[(2S)-2-({[(2S)-1-[(2S)-1-[(2S)-6-amino-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-amino-1-hydroxypropylidene]amino}-1-hydroxy-3-methylbutylidene]amino}-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino}-1,3-dihydroxypropylidene]amino}hexanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1,3-dihydroxypropylidene]amino}-1-hydroxyhexylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-3-carboxypropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyloxy]-3-{[(2S,3R)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2,6-diamino-1-hydroxyhexylidene]amino}-1-hydroxy-4-(methylsulphanyl)butylidene]amino}-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino}-1,3-dihydroxybutylidene]amino}-4-oxobutanoic acid
化学式: C85H144N26O28S (2009.0363584)
中文名称: 系统素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](C)N)=O)C(C)C)=O)CCC(N)=O)=O)CO)=O)CCCCN)=O)CCC1)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)[C@@H](C)O)=O)CCC(N)=O)=O)CCSC)=O)CCCCN)=O)CCC4)CCC3)CC(O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CO)=O)CCC2
InChI: InChI=1S/C85H144N26O28S/c1-43(2)65(106-67(121)44(3)89)77(131)100-49(25-27-61(91)115)71(125)104-55(41-112)75(129)101-52(19-8-11-32-88)79(133)109-35-14-22-58(109)81(135)108-34-13-21-57(108)76(130)105-56(42-113)74(128)98-47(18-7-10-31-87)69(123)97-48(20-12-33-95-85(93)94)70(124)102-53(39-63(117)118)80(134)110-36-15-23-59(110)82(136)111-37-16-24-60(111)84(138)139-83(137)54(40-64(119)120)103-78(132)66(45(4)114)107-73(127)50(26-28-62(92)116)99-72(126)51(29-38-140-5)96-68(122)46(90)17-6-9-30-86/h43-60,65-66,112-114H,6-42,86-90H2,1-5H3,(H2,91,115)(H2,92,116)(H,96,122)(H,97,123)(H,98,128)(H,99,126)(H,100,131)(H,101,129)(H,102,124)(H,103,132)(H,104,125)(H,105,130)(H,106,121)(H,107,127)(H,117,118)(H,119,120)(H4,93,94,95)/t44-,45+,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,65-,66-/m0/s1
描述信息
Systemin is found in garden tomato. Systemin is a constituent of the leaves of tomato (Lycopersicon esculentum) Systemin is a plant hormone involved in wound response. It was the first plant hormone that was proven to be a peptide. Systemin induces the production of protease inhibitors which protect against insect herbivores
Constituent of the leaves of tomato (Lycopersicon esculentum)
Systemin, an 18-amino acid polypeptide, has been isolated from tomato leaves that is a powerful inducer of over 15 defensive genes.
同义名列表
6 个代谢物同义名
(3S)-4-[(2S)-1-[(2S)-1-[(2S)-2-{[(2S)-2-{[(2S)-6-amino-2-{[(2S)-2-({[(2S)-1-[(2S)-1-[(2S)-6-amino-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-amino-1-hydroxypropylidene]amino}-1-hydroxy-3-methylbutylidene]amino}-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino}-1,3-dihydroxypropylidene]amino}hexanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1,3-dihydroxypropylidene]amino}-1-hydroxyhexylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-3-carboxypropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyloxy]-3-{[(2S,3R)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2,6-diamino-1-hydroxyhexylidene]amino}-1-hydroxy-4-(methylsulphanyl)butylidene]amino}-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino}-1,3-dihydroxybutylidene]amino}-4-oxobutanoic acid; (3S)-4-[(2S)-1-[(2S)-1-[(2S)-2-{[(2S)-2-{[(2S)-6-amino-2-{[(2S)-2-({[(2S)-1-[(2S)-1-[(2S)-6-amino-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-amino-1-hydroxypropylidene]amino}-1-hydroxy-3-methylbutylidene]amino}-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino}-1,3-dihydroxypropylidene]amino}hexanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1,3-dihydroxypropylidene]amino}-1-hydroxyhexylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-3-carboxypropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyloxy]-3-{[(2S,3R)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2,6-diamino-1-hydroxyhexylidene]amino}-1-hydroxy-4-(methylsulphanyl)butylidene]amino}-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino}-1,3-dihydroxybutylidene]amino}-4-oxobutanoate; (3S)-4-[(2S)-1-[(2S)-1-[(2S)-2-{[(2S)-2-{[(2S)-6-amino-2-{[(2S)-2-({[(2S)-1-[(2S)-1-[(2S)-6-amino-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-amino-1-hydroxypropylidene]amino}-1-hydroxy-3-methylbutylidene]amino}-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino}-1,3-dihydroxypropylidene]amino}hexanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1,3-dihydroxypropylidene]amino}-1-hydroxyhexylidene]amino}-5-carbamimidamido-1-hydroxypentylidene]amino}-3-carboxypropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyloxy]-3-{[(2S,3R)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2,6-diamino-1-hydroxyhexylidene]amino}-1-hydroxy-4-(methylsulfanyl)butylidene]amino}-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino}-1,3-dihydroxybutylidene]amino}-4-oxobutanoate; (3S)-3-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-1-[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-carboxypropanoyl]oxycarbonylpyrrolidine-1-carbonyl]pyrrolidin-1-yl]-4-oxobutanoic acid; (3S)-4-[(2S)-1-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-{[(2S)-1-[(2S)-1-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylbutanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]hexanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}-3-hydroxypropanamido]hexanamido]-5-[(diaminomethylidene)amino]pentanamido]-3-carboxypropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyloxy]-3-[(2S,3R)-2-[(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]-4-(methylsulfanyl)butanamido]butanamido]-3-hydroxybutanamido]-4-oxobutanoic acid; Systemin
数据库引用编号
9 个数据库交叉引用编号
- PubChem: 25078152
- HMDB: HMDB0030278
- Wikipedia: Systemin
- MeSH: systemin
- KNApSAcK: C00055103
- foodb: FDB002111
- chemspider: 17287891
- CAS: 137181-56-7
- medchemexpress: HY-P0279
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jijun Yan, Peiyong Xin, Shujing Cheng, Jinfang Chu. A sensitive and accurate method for quantifying endogenous systemin levels and verifying natural occurrence of Leu-Systemin.
Plant communications.
2023 09; 4(5):100638. doi:
10.1016/j.xplc.2023.100638. [PMID: 37301979] - J Pastor-Fernández, P Sánchez-Bel, J Gamir, V Pastor, N Sanmartín, M Cerezo, S Andrés-Moreno, V Flors. Tomato Systemin induces resistance against Plectosphaerella cucumerina in Arabidopsis through the induction of phenolic compounds and priming of tryptophan derivatives.
Plant science : an international journal of experimental plant biology.
2022 Aug; 321(?):111321. doi:
10.1016/j.plantsci.2022.111321. [PMID: 35696921] - Haiyan Zhang, Hui Zhang, Jinxing Lin. Systemin-mediated long-distance systemic defense responses.
The New phytologist.
2020 06; 226(6):1573-1582. doi:
10.1111/nph.16495. [PMID: 32083726] - Fatima Haj Ahmad, Xu Na Wu, Annick Stintzi, Andreas Schaller, Waltraud X Schulze. The Systemin Signaling Cascade As Derived from Time Course Analyses of the Systemin-responsive Phosphoproteome.
Molecular & cellular proteomics : MCP.
2019 08; 18(8):1526-1542. doi:
10.1074/mcp.ra119.001367. [PMID: 31138643] - Piotr Mucha, Jaroslaw Ruczynski, Michal Dobkowski, Ewelina Backtrog, Piotr Rekowski. Capillary electrophoresis study of systemin peptides spreading in tomato plant.
Electrophoresis.
2019 01; 40(2):336-342. doi:
10.1002/elps.201800206. [PMID: 30259532] - Josaphat Miguel Montero-Vargas, Kena Casarrubias-Castillo, Norma Martínez-Gallardo, José Juan Ordaz-Ortiz, John Paul Délano-Frier, Robert Winkler. Modulation of steroidal glycoalkaloid biosynthesis in tomato (Solanum lycopersicum) by jasmonic acid.
Plant science : an international journal of experimental plant biology.
2018 Dec; 277(?):155-165. doi:
10.1016/j.plantsci.2018.08.020. [PMID: 30466581] - Mélanie Rich, Pierre-Marc Delaux. Taking the step: from Evo-Devo to plant-microbe interaction evolution with the liverwort Marchantia.
The New phytologist.
2018 05; 218(3):882-884. doi:
10.1111/nph.15095. [PMID: 29658636] - Roman E Beloshistov, Konrad Dreizler, Raisa A Galiullina, Alexander I Tuzhikov, Marina V Serebryakova, Sven Reichardt, Jane Shaw, Michael E Taliansky, Jens Pfannstiel, Nina V Chichkova, Annick Stintzi, Andreas Schaller, Andrey B Vartapetian. Phytaspase-mediated precursor processing and maturation of the wound hormone systemin.
The New phytologist.
2018 05; 218(3):1167-1178. doi:
10.1111/nph.14568. [PMID: 28407256] - Lei Wang, Elias Einig, Marilia Almeida-Trapp, Markus Albert, Judith Fliegmann, Axel Mithöfer, Hubert Kalbacher, Georg Felix. The systemin receptor SYR1 enhances resistance of tomato against herbivorous insects.
Nature plants.
2018 03; 4(3):152-156. doi:
10.1038/s41477-018-0106-0. [PMID: 29459726] - Haiyan Zhang, Pengli Yu, Jiuhai Zhao, Hongling Jiang, Haiyang Wang, Yingfang Zhu, Miguel A Botella, Jozef Šamaj, Chuanyou Li, Jinxing Lin. Expression of tomato prosystemin gene in Arabidopsis reveals systemic translocation of its mRNA and confers necrotrophic fungal resistance.
The New phytologist.
2018 01; 217(2):799-812. doi:
10.1111/nph.14858. [PMID: 29105094] - Mariangela Coppola, Pasquale Cascone, Valentina Madonna, Ilaria Di Lelio, Francesco Esposito, Concetta Avitabile, Alessandra Romanelli, Emilio Guerrieri, Alessia Vitiello, Francesco Pennacchio, Rosa Rao, Giandomenico Corrado. Plant-to-plant communication triggered by systemin primes anti-herbivore resistance in tomato.
Scientific reports.
2017 Nov; 7(1):15522. doi:
10.1038/s41598-017-15481-8. [PMID: 29138416] - Giovanni Bubici, Anna Vittoria Carluccio, Livia Stavolone, Fabrizio Cillo. Prosystemin overexpression induces transcriptional modifications of defense-related and receptor-like kinase genes and reduces the susceptibility to Cucumber mosaic virus and its satellite RNAs in transgenic tomato plants.
PloS one.
2017; 12(2):e0171902. doi:
10.1371/journal.pone.0171902. [PMID: 28182745] - Saikat Dutta Chowdhury, Aditya K Sarkar, Ansuman Lahiri. Effect of Inactivating Mutations on Peptide Conformational Ensembles: The Plant Polypeptide Hormone Systemin.
Journal of chemical information and modeling.
2016 07; 56(7):1267-81. doi:
10.1021/acs.jcim.5b00666. [PMID: 27341535] - Michał Dobkowski, Aleksandra Szychowska, Małgorzata Pieszko, Anna Miszka, Monika Wojciechowska, Magdalena Alenowicz, Jarosław Ruczyński, Piotr Rekowski, Lech Celewicz, Jan Barciszewski, Piotr Mucha. 'Click' chemistry synthesis and capillary electrophoresis study of 1,4-linked 1,2,3-triazole AZT-systemin conjugate.
Journal of peptide science : an official publication of the European Peptide Society.
2014 Sep; 20(9):696-703. doi:
10.1002/psc.2653. [PMID: 24889517] - Yu Bai, Cuilan Chang, Fuyou Du, Zhijing Tan, Yu Bai, Huwei Liu. Combination of dynamic pH junction with capillary electrophoresis-mass spectrometry for the determination of systemins in plant samples.
Electrophoresis.
2014 Jul; 35(14):1984-8. doi:
10.1002/elps.201300434. [PMID: 24668451] - Yu Bai, Fuyou Du, Youyou Yang, Yu Bai, Huwei Liu. In-capillary non-covalent labeling and determination of tomato systemin with quantum dots in capillary electrophoresis with laser-induced fluorescence detection.
Journal of separation science.
2011 Oct; 34(20):2893-900. doi:
10.1002/jssc.201100551. [PMID: 21919200] - Yube Yamaguchi, Alisa Huffaker. Endogenous peptide elicitors in higher plants.
Current opinion in plant biology.
2011 Aug; 14(4):351-7. doi:
10.1016/j.pbi.2011.05.001. [PMID: 21636314] - Gregory Pearce. Systemin, hydroxyproline-rich systemin and the induction of protease inhibitors.
Current protein & peptide science.
2011 Aug; 12(5):399-408. doi:
10.2174/138920311796391106. [PMID: 21418016] - Tao Bing, Tianjun Chang, Xiaojuan Yang, Hongcheng Mei, Xiangjun Liu, Dihua Shangguan. G-quadruplex DNA aptamers generated for systemin.
Bioorganic & medicinal chemistry.
2011 Jul; 19(14):4211-9. doi:
10.1016/j.bmc.2011.05.061. [PMID: 21715176] - Jia-Qiang Sun, Hong-Ling Jiang, Chuan-You Li. Systemin/Jasmonate-mediated systemic defense signaling in tomato.
Molecular plant.
2011 Jul; 4(4):607-15. doi:
10.1093/mp/ssr008. [PMID: 21357647] - N I Vasiukova, G I Chalenko, N G Gerasimova, O L Ozeretskovskaia. [Wound repair in plant tissues (Review)].
Prikladnaia biokhimiia i mikrobiologiia.
2011 May; 47(3):253-8. doi:
". [PMID: 21790022] - Andrew N Gifford, Sonja Kuschel, Colleen Shea, Joanna S Fowler. Polymer-supported organotin reagent for prosthetic group labeling of biological macromolecules with radioiodine.
Bioconjugate chemistry.
2011 Mar; 22(3):406-12. doi:
10.1021/bc1004203. [PMID: 21309585] - David C Degenhardt, Sarah Refi-Hind, Johannes W Stratmann, David E Lincoln. Systemin and jasmonic acid regulate constitutive and herbivore-induced systemic volatile emissions in tomato, Solanum lycopersicum.
Phytochemistry.
2010 Dec; 71(17-18):2024-37. doi:
10.1016/j.phytochem.2010.09.010. [PMID: 20970815] - Sven Heiling, Meredith C Schuman, Matthias Schoettner, Purba Mukerjee, Beatrice Berger, Bernd Schneider, Amir R Jassbi, Ian T Baldwin. Jasmonate and ppHsystemin regulate key Malonylation steps in the biosynthesis of 17-Hydroxygeranyllinalool Diterpene Glycosides, an abundant and effective direct defense against herbivores in Nicotiana attenuata.
The Plant cell.
2010 Jan; 22(1):273-92. doi:
10.1105/tpc.109.071449. [PMID: 20081114] - Sarah R Hind, Robert Malinowski, Roopa Yalamanchili, Johannes W Stratmann. Tissue-type specific systemin perception and the elusive systemin receptor.
Plant signaling & behavior.
2010 Jan; 5(1):42-4. doi:
10.4161/psb.5.1.10119. [PMID: 20592806] - Francesco Orsini, Pasquale Cascone, Stefania De Pascale, Giancarlo Barbieri, Giandomenico Corrado, Rosa Rao, Albino Maggio. Systemin-dependent salinity tolerance in tomato: evidence of specific convergence of abiotic and biotic stress responses.
Physiologia plantarum.
2010 Jan; 138(1):10-21. doi:
10.1111/j.1399-3054.2009.01292.x. [PMID: 19843237] - Robert Malinowski, Rebecca Higgins, Yuan Luo, Laverne Piper, Azka Nazir, Vikramjit S Bajwa, Steven D Clouse, Paul R Thompson, Johannes W Stratmann. The tomato brassinosteroid receptor BRI1 increases binding of systemin to tobacco plasma membranes, but is not involved in systemin signaling.
Plant molecular biology.
2009 Jul; 70(5):603-16. doi:
10.1007/s11103-009-9494-x. [PMID: 19404750] - Gregory Pearce, Ramcharan Bhattacharya, Yu-Chi Chen, Guido Barona, Yube Yamaguchi, Clarence A Ryan. Isolation and characterization of hydroxyproline-rich glycopeptide signals in black nightshade leaves.
Plant physiology.
2009 Jul; 150(3):1422-33. doi:
10.1104/pp.109.138669. [PMID: 19403725] - Beatrice Berger, Ian T Baldwin. Silencing the hydroxyproline-rich glycopeptide systemin precursor in two accessions of Nicotiana attenuata alters flower morphology and rates of self-pollination.
Plant physiology.
2009 Apr; 149(4):1690-700. doi:
10.1104/pp.108.132928. [PMID: 19211701] - Silvia Schmidt, Ian T Baldwin. Down-regulation of systemin after herbivory is associated with increased root allocation and competitive ability in Solanum nigrum.
Oecologia.
2009 Mar; 159(3):473-82. doi:
10.1007/s00442-008-1230-8. [PMID: 19037662] - Mariapina Rocco, Giandomenico Corrado, Simona Arena, Chiara D'Ambrosio, Claudia Tortiglione, Stefano Sellaroli, Mauro Marra, Rosa Rao, Andrea Scaloni. The expression of tomato prosystemin gene in tobacco plants highly affects host proteomic repertoire.
Journal of proteomics.
2008 Jul; 71(2):176-85. doi:
10.1016/j.jprot.2008.04.003. [PMID: 18617145] - Frank C Lanfermeijer, Marten Staal, Robert Malinowski, Johannes W Stratmann, J Theo M Elzenga. Micro-electrode flux estimation confirms that the Solanum pimpinellifolium cu3 mutant still responds to systemin.
Plant physiology.
2008 Jan; 146(1):129-39. doi:
10.1104/pp.107.110643. [PMID: 18055585] - Javier Narváez-Vásquez, Martha L Orozco-Cárdenas, Clarence A Ryan. Systemic wound signaling in tomato leaves is cooperatively regulated by systemin and hydroxyproline-rich glycopeptide signals.
Plant molecular biology.
2007 Dec; 65(6):711-8. doi:
10.1007/s11103-007-9242-z. [PMID: 17899396] - Beatrice Berger, Ian T Baldwin. The hydroxyproline-rich glycopeptide systemin precursor NapreproHypSys does not play a central role in Nicotiana attenuata's anti-herbivore defense responses.
Plant, cell & environment.
2007 Nov; 30(11):1450-64. doi:
10.1111/j.1365-3040.2007.01719.x. [PMID: 17897415] - Pramod Kaitheri Kandoth, Stefanie Ranf, Suchita S Pancholi, Sastry Jayanty, Michael D Walla, Wayne Miller, Gregg A Howe, David E Lincoln, Johannes W Stratmann. Tomato MAPKs LeMPK1, LeMPK2, and LeMPK3 function in the systemin-mediated defense response against herbivorous insects.
Proceedings of the National Academy of Sciences of the United States of America.
2007 Jul; 104(29):12205-10. doi:
10.1073/pnas.0700344104. [PMID: 17623784] - Blanca de la Noval, Eduardo Pérez, Benedicto Martínez, Ondina León, Norma Martínez-Gallardo, John Délano-Frier. Exogenous systemin has a contrasting effect on disease resistance in mycorrhizal tomato (Solanum lycopersicum) plants infected with necrotrophic or hemibiotrophic pathogens.
Mycorrhiza.
2007 Jul; 17(5):449-460. doi:
10.1007/s00572-007-0122-9. [PMID: 17356854] - Nicholas Holton, Ana Caño-Delgado, Kate Harrison, Teresa Montoya, Joanne Chory, Gerard J Bishop. Tomato BRASSINOSTEROID INSENSITIVE1 is required for systemin-induced root elongation in Solanum pimpinellifolium but is not essential for wound signaling.
The Plant cell.
2007 May; 19(5):1709-17. doi:
10.1105/tpc.106.047795. [PMID: 17513502] - Rebecca Higgins, Thomas Lockwood, Susan Holley, Roopa Yalamanchili, Johannes W Stratmann. Changes in extracellular pH are neither required nor sufficient for activation of mitogen-activated protein kinases (MAPKs) in response to systemin and fusicoccin in tomato.
Planta.
2007 May; 225(6):1535-46. doi:
10.1007/s00425-006-0440-8. [PMID: 17109147] - G Corrado, R Sasso, M Pasquariello, L Iodice, A Carretta, P Cascone, L Ariati, M C Digilio, E Guerrieri, R Rao. Systemin regulates both systemic and volatile signaling in tomato plants.
Journal of chemical ecology.
2007 Apr; 33(4):669-81. doi:
10.1007/s10886-007-9254-9. [PMID: 17333376] - Jadwiga Szczegielniak. [Wound signal transduction pathways in plants].
Postepy biochemii.
2007; 53(2):121-32. doi:
". [PMID: 17969872] - Silvia Schmidt, Ian T Baldwin. Systemin in Solanum nigrum. The tomato-homologous polypeptide does not mediate direct defense responses.
Plant physiology.
2006 Dec; 142(4):1751-8. doi:
10.1104/pp.106.089755. [PMID: 17071641] - Claus Wasternack, Irene Stenzel, Bettina Hause, Gerd Hause, Claudia Kutter, Helmut Maucher, Jana Neumerkel, Ivo Feussner, Otto Miersch. The wound response in tomato--role of jasmonic acid.
Journal of plant physiology.
2006 Feb; 163(3):297-306. doi:
10.1016/j.jplph.2005.10.014. [PMID: 16368162] - Daniela Andrea Capiati, Silvia Marina País, María Teresa Téllez-Iñón. Wounding increases salt tolerance in tomato plants: evidence on the participation of calmodulin-like activities in cross-tolerance signalling.
Journal of experimental botany.
2006; 57(10):2391-400. doi:
10.1093/jxb/erj212. [PMID: 16766597] - Carmen del María Rocha-Granados, Carlos Sánchez-Hernández, Carla Sánchez-Hernández, Norma Angélica Martínez-Gallardo, Neftalí Ochoa-Alejo, John Paul Délano-Frier. The expression of the hydroxyproline-rich glycopeptide systemin precursor A in response to (a)biotic stress and elicitors is indicative of its role in the regulation of the wound response in tobacco (Nicotiana tabacum L.).
Planta.
2005 Nov; 222(5):794-810. doi:
10.1007/s00425-005-0024-z. [PMID: 16052320] - Nadine Gross, Claus Wasternack, Margret Köck. Wound-induced RNaseLE expression is jasmonate and systemin independent and occurs only locally in tomato (Lycopersicon esculentum cv. Lukullus).
Phytochemistry.
2004 May; 65(10):1343-50. doi:
10.1016/j.phytochem.2004.04.036. [PMID: 15231407] - Zhi-Yong Wang, Jun-Xian He. Brassinosteroid signal transduction--choices of signals and receptors.
Trends in plant science.
2004 Feb; 9(2):91-6. doi:
10.1016/j.tplants.2003.12.009. [PMID: 15102375] - Claudia Tortiglione, Vincenzo Fogliano, Rosalia Ferracane, Paolo Fanti, Francesco Pennacchio, Luigi Maria Monti, Rosa Rao. An insect peptide engineered into the tomato prosystemin gene is released in transgenic tobacco plants and exerts biological activity.
Plant molecular biology.
2003 Dec; 53(6):891-902. doi:
10.1023/b:plan.0000023667.62501.ef. [PMID: 15082933] - Yoshikatsu Matsubayashi. Ligand-receptor pairs in plant peptide signaling.
Journal of cell science.
2003 Oct; 116(Pt 19):3863-70. doi:
10.1242/jcs.00733. [PMID: 12953055] - Alessandra Devoto, John G Turner. Regulation of jasmonate-mediated plant responses in arabidopsis.
Annals of botany.
2003 Sep; 92(3):329-37. doi:
10.1093/aob/mcg151. [PMID: 12871847] - Justin M Scheer, Gregory Pearce, Clarence A Ryan. Generation of systemin signaling in tobacco by transformation with the tomato systemin receptor kinase gene.
Proceedings of the National Academy of Sciences of the United States of America.
2003 Aug; 100(17):10114-7. doi:
10.1073/pnas.1432910100. [PMID: 12900501] - Gregory Pearce, Clarence A Ryan. Systemic signaling in tomato plants for defense against herbivores. Isolation and characterization of three novel defense-signaling glycopeptide hormones coded in a single precursor gene.
The Journal of biological chemistry.
2003 Aug; 278(32):30044-50. doi:
10.1074/jbc.m304159200. [PMID: 12748180] - Erin R Morris, John C Walker. Receptor-like protein kinases: the keys to response.
Current opinion in plant biology.
2003 Aug; 6(4):339-42. doi:
10.1016/s1369-5266(03)00055-4. [PMID: 12873528] - Susan R Holley, Roopa D Yalamanchili, Daniel S Moura, Clarence A Ryan, Johannes W Stratmann. Convergence of signaling pathways induced by systemin, oligosaccharide elicitors, and ultraviolet-B radiation at the level of mitogen-activated protein kinases in Lycopersicon peruvianum suspension-cultured cells.
Plant physiology.
2003 Aug; 132(4):1728-38. doi:
10.1104/pp.103.024414. [PMID: 12913131] - Chuanyou Li, Guanghui Liu, Changcheng Xu, Gyu In Lee, Petra Bauer, Hong-Qing Ling, Martin W Ganal, Gregg A Howe. The tomato suppressor of prosystemin-mediated responses2 gene encodes a fatty acid desaturase required for the biosynthesis of jasmonic acid and the production of a systemic wound signal for defense gene expression.
The Plant cell.
2003 Jul; 15(7):1646-61. doi:
10.1105/tpc.012237. [PMID: 12837953] - Johannes W Stratmann. Long distance run in the wound response--jasmonic acid is pulling ahead.
Trends in plant science.
2003 Jun; 8(6):247-50. doi:
10.1016/s1360-1385(03)00106-7. [PMID: 12818656] - Miklos Szekeres. Brassinosteroid and systemin: two hormones perceived by the same receptor.
Trends in plant science.
2003 Mar; 8(3):102-4. doi:
10.1016/s1360-1385(03)00010-4. [PMID: 12663218] - Irene Stenzel, Bettina Hause, Helmut Maucher, Andrea Pitzschke, Otto Miersch, Jörg Ziegler, Clarence A Ryan, Claus Wasternack. Allene oxide cyclase dependence of the wound response and vascular bundle-specific generation of jasmonates in tomato - amplification in wound signalling.
The Plant journal : for cell and molecular biology.
2003 Feb; 33(3):577-89. doi:
10.1046/j.1365-313x.2003.01647.x. [PMID: 12581315] - Gyu In Lee, Gregg A Howe. The tomato mutant spr1 is defective in systemin perception and the production of a systemic wound signal for defense gene expression.
The Plant journal : for cell and molecular biology.
2003 Feb; 33(3):567-76. doi:
10.1046/j.1365-313x.2003.01646.x. [PMID: 12581314] - Paul Chilley. Polypeptide hormones: signaling molecules in plants.
Vitamins and hormones.
2003; 66(?):317-44. doi:
10.1016/s0083-6729(03)01009-4. [PMID: 12852259] - Teresa Montoya, Takahito Nomura, Kerrie Farrar, Tsuyoshi Kaneta, Takao Yokota, Gerard J Bishop. Cloning the tomato curl3 gene highlights the putative dual role of the leucine-rich repeat receptor kinase tBRI1/SR160 in plant steroid hormone and peptide hormone signaling.
The Plant cell.
2002 Dec; 14(12):3163-76. doi:
10.1105/tpc.006379. [PMID: 12468734] - Seiji Takayama, Youji Sakagami. Peptide signalling in plants.
Current opinion in plant biology.
2002 Oct; 5(5):382-7. doi:
10.1016/s1369-5266(02)00284-4. [PMID: 12183175] - Martha L Orozco-Cárdenas, Clarence A Ryan. Nitric oxide negatively modulates wound signaling in tomato plants.
Plant physiology.
2002 Sep; 130(1):487-93. doi:
10.1104/pp.008375. [PMID: 12226527] - Justin M Scheer, Clarence A Ryan. The systemin receptor SR160 from Lycopersicon peruvianum is a member of the LRR receptor kinase family.
Proceedings of the National Academy of Sciences of the United States of America.
2002 Jul; 99(14):9585-90. doi:
10.1073/pnas.132266499. [PMID: 12060717] - Yanhai Yin, Dongying Wu, Joanne Chory. Plant receptor kinases: systemin receptor identified.
Proceedings of the National Academy of Sciences of the United States of America.
2002 Jul; 99(14):9090-2. doi:
10.1073/pnas.152330799. [PMID: 12093928] - Clarence A Ryan, Daniel S Moura. Systemic wound signaling in plants: a new perception.
Proceedings of the National Academy of Sciences of the United States of America.
2002 May; 99(10):6519-20. doi:
10.1073/pnas.112196499. [PMID: 12011413] - Keith Lindsey, Stuart Casson, Paul Chilley. Peptides: new signalling molecules in plants.
Trends in plant science.
2002 Feb; 7(2):78-83. doi:
10.1016/s1360-1385(01)02194-x. [PMID: 11832279] - Clarence A Ryan, Gregory Pearce, Justin Scheer, Daniel S Moura. Polypeptide hormones.
The Plant cell.
2002; 14 Suppl(?):S251-64. doi:
10.1105/tpc.010484. [PMID: 12045281] - L Li, C Li, G A Howe. Genetic analysis of wound signaling in tomato. Evidence for a dual role of jasmonic acid in defense and female fertility.
Plant physiology.
2001 Dec; 127(4):1414-7. doi:
10.1104/pp.010705. [PMID: 11743083] - K Lindsey. Plant peptide hormones: The long and the short of it.
Current biology : CB.
2001 Sep; 11(18):R741-3. doi:
10.1016/s0960-9822(01)00435-3. [PMID: 11566117] - G Pearce, D S Moura, J Stratmann, C A Ryan. Production of multiple plant hormones from a single polyprotein precursor.
Nature.
2001 Jun; 411(6839):817-20. doi:
10.1038/35081107. [PMID: 11459063] - D S Moura, C A Ryan. Wound-inducible proteinase inhibitors in pepper. Differential regulation upon wounding, systemin, and methyl jasmonate.
Plant physiology.
2001 May; 126(1):289-98. doi:
10.1104/pp.126.1.289. [PMID: 11351092] - M L Orozco-Cárdenas, J Narváez-Vásquez, C A Ryan. Hydrogen peroxide acts as a second messenger for the induction of defense genes in tomato plants in response to wounding, systemin, and methyl jasmonate.
The Plant cell.
2001 Jan; 13(1):179-91. doi:
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Journal of experimental botany.
2001 Jan; 52(354):1-9. doi:
10.1093/jexbot/52.354.1. [PMID: 11181708] - J Stratmann, J Scheer, C A Ryan. Suramin inhibits initiation of defense signaling by systemin, chitosan, and a beta-glucan elicitor in suspension-cultured Lycopersicon peruvianum cells.
Proceedings of the National Academy of Sciences of the United States of America.
2000 Aug; 97(16):8862-7. doi:
10.1073/pnas.97.16.8862. [PMID: 10922047] - M Vetsch, I Janzik, A Schaller. Characterization of prosystemin expressed in the baculovirus/insect cell system reveals biological activity of the systemin precursor.
Planta.
2000 Jun; 211(1):91-7. doi:
10.1007/s004250000264. [PMID: 10923708] - C A Ryan. The systemin signaling pathway: differential activation of plant defensive genes.
Biochimica et biophysica acta.
2000 Mar; 1477(1-2):112-21. doi:
10.1016/s0167-4838(99)00269-1. [PMID: 10708853] - G A Howe, C A Ryan. Suppressors of systemin signaling identify genes in the tomato wound response pathway.
Genetics.
1999 Nov; 153(3):1411-21. doi:
10.1093/genetics/153.3.1411. [PMID: 10545469] - K Hara, H Sano. [Control of wound-responsive gene expression].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.
1999 Nov; 44(15 Suppl):2353-9. doi:
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Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.
1999 Nov; 44(15 Suppl):2347-52. doi:
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Current opinion in plant biology.
1999 Oct; 2(5):365-8. doi:
10.1016/s1369-5266(99)00006-0. [PMID: 10508757] - A Schaller. Oligopeptide signalling and the action of systemin.
Plant molecular biology.
1999 Jul; 40(5):763-9. doi:
10.1023/a:1006279409687. [PMID: 10487211] - D R Bergey, C A Ryan. Wound- and systemin-inducible calmodulin gene expression in tomato leaves.
Plant molecular biology.
1999 Jul; 40(5):815-23. doi:
10.1023/a:1006247624823. [PMID: 10487216] - M Orozco-Cardenas, C A Ryan. Hydrogen peroxide is generated systemically in plant leaves by wounding and systemin via the octadecanoid pathway.
Proceedings of the National Academy of Sciences of the United States of America.
1999 May; 96(11):6553-7. doi:
10.1073/pnas.96.11.6553. [PMID: 10339626] - D R Bergey, M Orozco-Cardenas, D S de Moura, C A Ryan. A wound- and systemin-inducible polygalacturonase in tomato leaves.
Proceedings of the National Academy of Sciences of the United States of America.
1999 Feb; 96(4):1756-60. doi:
10.1073/pnas.96.4.1756. [PMID: 9990097] - A Schaller, C Oecking. Modulation of plasma membrane H+-ATPase activity differentially activates wound and pathogen defense responses in tomato plants.
The Plant cell.
1999 Feb; 11(2):263-72. doi:
10.1105/tpc.11.2.263. [PMID: 9927643] - D Bowles. Signal transduction in the wound response of tomato plants.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
1998 Sep; 353(1374):1495-510. doi:
10.1098/rstb.1998.0305. [PMID: 9800210] - T Meindl, T Boller, G Felix. The plant wound hormone systemin binds with the N-terminal part to its receptor but needs the C-terminal part to activate it.
The Plant cell.
1998 Sep; 10(9):1561-70. doi:
10.1105/tpc.10.9.1561. [PMID: 9724701] - H Hirano. [Structure and function of hormone-like peptides in plants].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.
1998 Apr; 43(5):649-61. doi:
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Phytochemistry.
1998 Feb; 47(4):605-12. doi:
10.1016/s0031-9422(97)00523-2. [PMID: 9461676] - C A Ryan, G Pearce. Systemin: a polypeptide signal for plant defensive genes.
Annual review of cell and developmental biology.
1998; 14(?):1-17. doi:
10.1146/annurev.cellbio.14.1.1. [PMID: 9891776] - C P Constabel, L Yip, C A Ryan. Prosystemin from potato, black nightshade, and bell pepper: primary structure and biological activity of predicted systemin polypeptides.
Plant molecular biology.
1998 Jan; 36(1):55-62. doi:
10.1023/a:1005986004615. [PMID: 9484462] - J W Stratmann, C A Ryan. Myelin basic protein kinase activity in tomato leaves is induced systemically by wounding and increases in response to systemin and oligosaccharide elicitors.
Proceedings of the National Academy of Sciences of the United States of America.
1997 Sep; 94(20):11085-9. doi:
10.1073/pnas.94.20.11085. [PMID: 9380763] - T Heitz, D R Bergey, C A Ryan. A gene encoding a chloroplast-targeted lipoxygenase in tomato leaves is transiently induced by wounding, systemin, and methyl jasmonate.
Plant physiology.
1997 Jul; 114(3):1085-93. doi:
10.1104/pp.114.3.1085. [PMID: 9232884] - J Barciszewski, A B Legocki. Two plant signalling peptides: systemin and ENOD 40.
Acta biochimica Polonica.
1997; 44(4):795-802. doi:
10.18388/abp.1997_4384. [PMID: 9584862] - D R Bergey, G A Howe, C A Ryan. Polypeptide signaling for plant defensive genes exhibits analogies to defense signaling in animals.
Proceedings of the National Academy of Sciences of the United States of America.
1996 Oct; 93(22):12053-8. doi:
10.1073/pnas.93.22.12053. [PMID: 8901530] - A Schaller, C A Ryan. Molecular cloning of a tomato leaf cDNA encoding an aspartic protease, a systemic wound response protein.
Plant molecular biology.
1996 Aug; 31(5):1073-7. doi:
10.1007/bf00040725. [PMID: 8843949] - A Schaller, C A Ryan. Systemin--a polypeptide defense signal in plants.
BioEssays : news and reviews in molecular, cellular and developmental biology.
1996 Jan; 18(1):27-33. doi:
10.1002/bies.950180108. [PMID: 8593160] - A Schaller, D R Bergey, C A Ryan. Induction of wound response genes in tomato leaves by bestatin, an inhibitor of aminopeptidases.
The Plant cell.
1995 Nov; 7(11):1893-8. doi:
10.1105/tpc.7.11.1893. [PMID: 8535142] - G Slósarek, H R Kalbitzer, P Mucha, P Rekowski, G Kupryszewski, M Giel-Pietraszuk, M Szymański, J Barciszewski. Mechanism of the activation of proteinase inhibitor synthesis by systemin involves beta-sheet structure, a specific DNA-binding protein domain.
Journal of structural biology.
1995 Jul; 115(1):30-6. doi:
10.1006/jsbi.1995.1026. [PMID: 7577230]