Benzoylaconine (BioDeep_00000176580)
Main id: BioDeep_00000230477
human metabolite PANOMIX_OTCML-2023 blood metabolite
代谢物信息卡片
化学式: C32H45NO10 (603.304331)
中文名称: 苯甲酰乌头原碱
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN1CC2(C(CC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)O)OC)OC)O)COC
InChI: InChI=1S/C32H45NO10/c1-6-33-14-29(15-39-2)18(34)12-19(40-3)31-17-13-30(37)26(43-28(36)16-10-8-7-9-11-16)20(17)32(38,25(35)27(30)42-5)21(24(31)33)22(41-4)23(29)31/h7-11,17-27,34-35,37-38H,6,12-15H2,1-5H3
描述信息
Benzoylaconine (Isaconitine; Pikraconitin) is aconite alkaloid in traditional Chinese medicine.
Benzoylaconine (Isaconitine; Pikraconitin) is aconite alkaloid in traditional Chinese medicine.
同义名列表
8 个代谢物同义名
11-Ethyl-5,7,8,14-tetrahydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecan-4-yl benzoic acid; 11-ethyl-5,7,8,14-tetrahydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecan-4-yl benzoate; 11-Ethyl-5,7,8,14-tetrahydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1,.0,.0,.0,]nonadecan-4-yl benzoic acid; benzoyl-aconine; benzoylaconine; CID 15559774; Isaconitine; Pikraconitin
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xiaocui Li, Weiqing Hou, Tingting Lin, Jiadong Ni, Huawei Qiu, Yu Fu, Zhongxiang Zhao, Caihua Yang, Na Li, Hua Zhou, Rong Zhang, Zhongqiu Liu, Ling Fu, Lijun Zhu. Neoline, fuziline, songorine and 10-OH mesaconitine are potential quality markers of Fuzi: In vitro and in vivo explorations as well as pharmacokinetics, efficacy and toxicity evaluations.
Journal of ethnopharmacology.
2023 Mar; 303(?):115879. doi:
10.1016/j.jep.2022.115879. [PMID: 36370966] - Chao Liu, Nabil Farah, Wei Weng, Baixin Jiao, Meiyue Shen, Liang Fang. Investigation of the permeation enhancer strategy on benzoylaconitine transdermal patch: the relationship between transdermal enhancement strength and physicochemical properties of permeation enhancer.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2019 Oct; 138(?):105009. doi:
10.1016/j.ejps.2019.105009. [PMID: 31306781] - Yohei Tanimura, Masato Yoshida, Kan'ichiro Ishiuchi, Masahiro Ohsawa, Toshiaki Makino. Neoline is the active ingredient of processed aconite root against murine peripheral neuropathic pain model, and its pharmacokinetics in rats.
Journal of ethnopharmacology.
2019 Sep; 241(?):111859. doi:
10.1016/j.jep.2019.111859. [PMID: 30974202] - Xiao-Hong Deng, Jing-Jing Liu, Xian-Jun Sun, Jing-Cheng Dong, Jian-Hua Huang. Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.
Acta pharmacologica Sinica.
2019 May; 40(5):658-665. doi:
10.1038/s41401-018-0174-8. [PMID: 30315253] - Ahmatbeck Samanbay, Bo Zhao, Haji Akber Aisa. A new denudatine type C20-diterpenoid alkaloid from Aconitum sinchiangense W. T. Wang.
Natural product research.
2018 Oct; 32(19):2319-2324. doi:
10.1080/14786419.2017.1410814. [PMID: 29212360] - Shaohua Li, Dawei Chen. Rapid Determination of Aconitum Alkaloids from Human Urine by UHPLC-HRMS.
Journal of analytical toxicology.
2017 Sep; 41(7):611-617. doi:
10.1093/jat/bkx045. [PMID: 28873976] - Hai Zhang, Sen Sun, Wen Zhang, Xiangqun Xie, Zhenyu Zhu, Yifeng Chai, Guoqing Zhang. Biological activities and pharmacokinetics of aconitine, benzoylaconine, and aconine after oral administration in rats.
Drug testing and analysis.
2016 Aug; 8(8):839-46. doi:
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Scientific reports.
2016 05; 6(?):25343. doi:
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Journal of analytical toxicology.
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Journal of ethnopharmacology.
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Journal of pharmaceutical and biomedical analysis.
2013 Apr; 77(?):88-93. doi:
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Yao xue xue bao = Acta pharmaceutica Sinica.
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Phytochemical analysis : PCA.
2010 Mar; 21(2):137-43. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2008 Oct; 873(2):173-9. doi:
10.1016/j.jchromb.2008.08.008. [PMID: 18778973] - Xiu-xiu Liu, Ruo-bing Chao. [Determination of alkaloids in Radix Aconiti Lateralis Preparata by RP-ion-pair HPLC].
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Forensic science international.
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Legal medicine (Tokyo, Japan).
2003 Mar; 5 Suppl 1(?):S101-4. doi:
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