2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)- (BioDeep_00000175777)
human metabolite blood metabolite
代谢物信息卡片
化学式: C20H20N2O3 (336.147385)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: OC1=C(O)C=C(C=C(C#N)C(=O)NCCCCC2=CC=CC=C2)C=C1
InChI: InChI=1S/C20H20N2O3/c21-14-17(12-16-9-10-18(23)19(24)13-16)20(25)22-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,23-24H,4-5,8,11H2,(H,22,25)
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Wei Wu, Hai-Ying Sun, Xiu-Ling Deng, Gui-Rong Li. EGFR tyrosine kinase regulates human small-conductance Ca2+-activated K+ (hSKCa1) channels expressed in HEK-293 cells.
The Biochemical journal.
2013 May; 452(1):121-9. doi:
10.1042/bj20121324. [PMID: 23496660] - Srinivasan Balachandra, Tiziana Genovese, Emanuela Mazzon, Rosanna Di Paola, Christoph Thiemerman, Ajith K Siriwardena, Salvatore Cuzzocrea. Inhibition of tyrosine-kinase-mediated cellular signaling by tyrphostins AG 126 and AG556 modulates murine experimental acute pancreatitis.
Surgery.
2005 Nov; 138(5):913-23. doi:
10.1016/j.surg.2005.05.021. [PMID: 16291393] - Haydar Usul, Ertugrul Cakir, Umit Cobanoglu, Ahmet Alver, Bekircan Peksoylu, Murat Topbas, Suleyman Baykal. The effects of tyrphostine Ag 556 on experimental spinal cord ischemia reperfusion injury.
Surgical neurology.
2004 Jan; 61(1):45-54; discussion 54. doi:
10.1016/s0090-3019(03)00539-1. [PMID: 14706378] - Amandine Hurbin, Laurence Dubrez, Jean-Luc Coll, Marie-Christine Favrot. Inhibition of apoptosis by amphiregulin via an insulin-like growth factor-1 receptor-dependent pathway in non-small cell lung cancer cell lines.
The Journal of biological chemistry.
2002 Dec; 277(51):49127-33. doi:
10.1074/jbc.m207584200. [PMID: 12356750] - Chern-En Chiang, Hsiang-Ning Luk, Tsui-Min Wang, Joen-Rong Sheu, Philip Yu-An Ding. Genistein and tyrphostin AG 556 block the action potential shortening in septic shock.
Zhonghua yi xue za zhi = Chinese medical journal; Free China ed.
2002 Dec; 65(12):570-9. doi:
NULL. [PMID: 12636202] - D Altavilla, F Squadrito, G M Campo, A Saitta, G Squadrito, C Quartarone, B Deodato, M Arlotta, M Ferlito, L Minutoli, M Tringali, G Urna, A Sardella, A P Caputi. The reduction of myocardial damage and leukocyte polymorphonuclear accumulation following coronary artery occlusion by the tyrosine kinase inhibitor tyrphostin AG 556.
Life sciences.
2000 Oct; 67(21):2615-29. doi:
10.1016/s0024-3205(00)00845-6. [PMID: 11104363] - S Ogura, O Umegaki, F Genovese, L P Fernando, J B Cochran, C M Romeo, J A Cook. Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria.
Shock (Augusta, Ga.).
1999 Aug; 12(2):105-10. doi:
10.1097/00024382-199908000-00003. [PMID: 10446890] - M Kobari, B Kullenberg, A Björkman, S Matsuno, I Ihse, J Axelson. The inhibitory effect of an EGF receptor-specific tyrosine kinase inhibitor on pancreatic cancer cell lines was more potent than inhibitory antibodies against the receptors for EGF and IGF I.
International journal of pancreatology : official journal of the International Association of Pancreatology.
1998 Oct; 24(2):85-95. doi:
10.1007/bf02788565. [PMID: 9816541] - N Kleinberger-Doron, N Shelah, R Capone, A Gazit, A Levitzki. Inhibition of Cdk2 activation by selected tyrphostins causes cell cycle arrest at late G1 and S phase.
Experimental cell research.
1998 Jun; 241(2):340-51. doi:
10.1006/excr.1998.4061. [PMID: 9637776] - J E Sevransky, G Shaked, A Novogrodsky, A Levitzki, A Gazit, A Hoffman, R J Elin, Z M Quezado, B D Freeman, P Q Eichacker, R L Danner, S M Banks, J Bacher, M L Thomas, C Natanson. Tyrphostin AG 556 improves survival and reduces multiorgan failure in canine Escherichia coli peritonitis.
The Journal of clinical investigation.
1997 Apr; 99(8):1966-73. doi:
10.1172/jci119364. [PMID: 9109441]