(S)-3-(Azetidin-2-ylmethoxy)pyridine (BioDeep_00000175502)
human metabolite blood metabolite
代谢物信息卡片
(S)-3-(Azetidin-2-ylmethoxy)pyridine
化学式: C9H12N2O (164.09495819999998)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(OC1=CN=CC=C1)C1CCN1
InChI: InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2
数据库引用编号
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相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Arthur L Brody, Alexey G Mukhin, Jaime La Charite, Karen Ta, Judah Farahi, Catherine A Sugar, Michael S Mamoun, Evan Vellios, Meena Archie, Maggie Kozman, Jonathan Phuong, Franca Arlorio, Mark A Mandelkern. Up-regulation of nicotinic acetylcholine receptors in menthol cigarette smokers.
The international journal of neuropsychopharmacology.
2013 Jun; 16(5):957-66. doi:
10.1017/s1461145712001022. [PMID: 23171716] - Ekrem Maloku, Bashkim Kadriu, Adrian Zhubi, Erbo Dong, Fabio Pibiri, Rosalba Satta, Alessandro Guidotti. Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2011 Jun; 36(7):1366-74. doi:
10.1038/npp.2011.21. [PMID: 21368748] - Luping Z Huang, Carla Campos, Jason Ly, F Ivy Carroll, Maryka Quik. Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats.
Neuropharmacology.
2011 May; 60(6):861-8. doi:
10.1016/j.neuropharm.2010.12.032. [PMID: 21232546] - Jean-Dominique Gallezot, Michel A Bottlaender, Jacques Delforge, Héric Valette, Wadad Saba, Frédéric Dollé, Christine M Coulon, Michèle P Ottaviani, Françoise Hinnen, André Syrota, Marie-Claude Grégoire. Quantification of cerebral nicotinic acetylcholine receptors by PET using 2-[18F]fluoro-A-85380 and the multiinjection approach.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2008 Jan; 28(1):172-89. doi:
10.1038/sj.jcbfm.9600505. [PMID: 17519978] - Naomi M Warren, Margaret A Piggott, Elizabeth Greally, Michelle Lake, Andrew J Lees, David J Burn. Basal ganglia cholinergic and dopaminergic function in progressive supranuclear palsy.
Movement disorders : official journal of the Movement Disorder Society.
2007 Aug; 22(11):1594-600. doi:
10.1002/mds.21573. [PMID: 17534953] - D Bruce Vaupel, Elliot A Stein, Alexey G Mukhin. Quantification of alpha4beta2* nicotinic receptors in the rat brain with microPET and 2-[18F]F-A-85380.
NeuroImage.
2007 Feb; 34(4):1352-62. doi:
10.1016/j.neuroimage.2006.10.036. [PMID: 17187994] - Mirko Moroni, Ruud Zwart, Emanuele Sher, Bruce K Cassels, Isabel Bermudez. alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine.
Molecular pharmacology.
2006 Aug; 70(2):755-68. doi:
10.1124/mol.106.023044. [PMID: 16720757] - Masahiro Ohtani, Takami Oka, Maryna Badyuk, Yingxian Xiao, Kenneth J Kellar, John W Daly. Mouse beta-TC6 insulinoma cells: high expression of functional alpha3beta4 nicotinic receptors mediating membrane potential, intracellular calcium, and insulin release.
Molecular pharmacology.
2006 Mar; 69(3):899-907. doi:
10.1124/mol.105.014902. [PMID: 16332988] - Héric Valette, Michel Bottlaender, Frédéric Dollé, Christine Coulon, Michèle Ottaviani, André Syrota. Acute effects of physostigmine and galantamine on the binding of [18F]fluoro-A-85380: a PET study in monkeys.
Synapse (New York, N.Y.).
2005 Jun; 56(4):217-21. doi:
10.1002/syn.20145. [PMID: 15803498] - A Lai, J Sum, H Fan, J M McIntosh, M Quik. Selective recovery of striatal 125I-alpha-conotoxinmii nicotinic receptors after nigrostriatal damage in monkeys.
Neuroscience.
2004; 127(2):399-408. doi:
10.1016/j.neuroscience.2004.04.059. [PMID: 15262330] - Amy M Avila, Martha I Dávila-García, Veronica S Ascarrunz, YingxIan Xiao, Kenneth J Kellar. Differential regulation of nicotinic acetylcholine receptors in PC12 cells by nicotine and nerve growth factor.
Molecular pharmacology.
2003 Oct; 64(4):974-86. doi:
10.1124/mol.64.4.974. [PMID: 14500754] - Masahiro Fujita, Mohammed S Al-Tikriti, Gilles Tamagnan, Sami S Zoghbi, Ali Bozkurt, Ronald M Baldwin, Robert B Innis. Influence of acetylcholine levels on the binding of a SPECT nicotinic acetylcholine receptor ligand [123I]5-I-A-85380.
Synapse (New York, N.Y.).
2003 Jun; 48(3):116-22. doi:
10.1002/syn.10194. [PMID: 12645036] - Svetlana I Chefer, Edythe D London, Andrei O Koren, Olga A Pavlova, Varughese Kurian, Alane S Kimes, Andrew G Horti, Alexey G Mukhin. Graphical analysis of 2-[18F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain.
Synapse (New York, N.Y.).
2003 Apr; 48(1):25-34. doi:
10.1002/syn.10180. [PMID: 12557269] - Christopher M Butt, Scott R Hutton, Michael J Marks, Allan C Collins. Bovine serum albumin enhances nicotinic acetylcholine receptor function in mouse thalamic synaptosomes.
Journal of neurochemistry.
2002 Oct; 83(1):48-56. doi:
10.1046/j.1471-4159.2002.01135.x. [PMID: 12358728] - David C Perry, Yingxian Xiao, Henry N Nguyen, John L Musachio, Martha I Dávila-García, Kenneth J Kellar. Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography.
Journal of neurochemistry.
2002 Aug; 82(3):468-81. doi:
10.1046/j.1471-4159.2002.00951.x. [PMID: 12153472]