4',4',5,5',7,7'-Hexahydroxy-3,8'-biflavone (BioDeep_00000017541)

Main id: BioDeep_00000407437

 

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

化学式: C30H18O10 (538.0899928)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(OC5=CC(=CC(=C5C4=O)O)O)C6=CC=C(C=C6)O)O
InChI: InChI=1S/C30H18O10/c31-15-5-1-13(2-6-15)22-12-21(37)24-19(35)11-20(36)26(30(24)39-22)27-28(38)25-18(34)9-17(33)10-23(25)40-29(27)14-3-7-16(32)8-4-14/h1-12,31-36H

描述信息

4,4,5,5,7,7-Hexahydroxy-3,8-biflavone is a flavonoid oligomer.
3,8-Biapigenin is a natural product found in Hypericum montbretii, Hypericum scabrum, and other organisms with data available.
4,4,5,5,7,7-Hexahydroxy-3,8-biflavone is found in cereals and cereal products. 4,4,5,5,7,7-Hexahydroxy-3,8-biflavone is isolated from Fagopyrum esculentum (buckwheat).
Isolated from Fagopyrum esculentum (buckwheat). 3,8-Biapigenin is found in cereals and cereal products.
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors

同义名列表

22 个代谢物同义名

8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one; 3-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one; 5,5,7,7-Tetrahydroxy-2,2-bis(4-hydroxyphenyl)-[3,8-bi-4H-1-benzopyran]-4,4-dione, 9CI; [3,8-Bi-4H-1-benzopyran]-4,4-dione, 5,5,7,7-tetrahydroxy-2,2-bis(4-hydroxyphenyl)-; 5,5,7,7-Tetrahydroxy-2,2-bis(4-hydroxyphenyl)-4H,4H-[3,8-bichromene]-4,4-dione; 1,3-Benzodioxole-5-propanol, alpha-methyl-, 5-acetate; 1,3-Benzodioxole-5-propanol, alpha-methyl-, acetate; alpha-Methyl-1,3-benzodioxole-5-propanol, acetate; 3-(1,3-Benzodioxol-5-yl)-1-methylpropyl acetate; I3,II8-Biapigenin, analytical standard; 4,4,5,5,7,7-Hexahydroxy-3,8-biflavone; Biapigenin; I3,II8-Biapigenin; 13,Ii8-Biapigenin; 13Ii8-biapigenin; 3,8-Biapigenin; 3,8-biapigenin; 38-Biapigenin; MEGxp0_000393; ACon1_000118; bi-apigenin; biapigenin



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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INOH(0)

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10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Phi-Hung Nguyen, Da-Jung Ji, Yu-Ran Han, Jae-Sue Choi, Dong-Young Rhyu, Byung-Sun Min, Mi-Hee Woo. Selaginellin and biflavonoids as protein tyrosine phosphatase 1B inhibitors from Selaginella tamariscina and their glucose uptake stimulatory effects. Bioorganic & medicinal chemistry. 2015 Jul; 23(13):3730-7. doi: 10.1016/j.bmc.2015.04.007. [PMID: 25907369]
  • Hans Michler, Gregor Laakmann, Hildebert Wagner. Development of an LC-MS method for simultaneous quantitation of amentoflavone and biapigenin, the minor and major biflavones from Hypericum perforatum L., in human plasma and its application to real blood. Phytochemical analysis : PCA. 2011 Jan; 22(1):42-50. doi: 10.1002/pca.1249. [PMID: 20821812]
  • Adolf Nahrstedt, Veronika Butterweck. Lessons learned from herbal medicinal products: the example of St. John's Wort (perpendicular). Journal of natural products. 2010 May; 73(5):1015-21. doi: 10.1021/np1000329. [PMID: 20408551]
  • Bruno Silva, Paulo J Oliveira, Alberto Dias, Joao O Malva. Quercetin, kaempferol and biapigenin from Hypericum perforatum are neuroprotective against excitotoxic insults. Neurotoxicity research. 2008 May; 13(3-4):265-79. doi: 10.1007/bf03033510. [PMID: 18522906]
  • Milena Colovic, Silvio Caccia. Liquid chromatography-tandem mass spectrometry of I3,II8-biapigenin, the major biflavone in Hypericum perforatum extracts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2008 Feb; 863(1):74-9. doi: 10.1016/j.jchromb.2008.01.014. [PMID: 18243074]
  • Naonobu Tanaka, Yoshihisa Takaishi, Yasuhiro Shikishima, Yuka Nakanishi, Kenneth Bastow, Kuo-Hsiung Lee, Gisho Honda, Michiho Ito, Yoshio Takeda, Olimjon K Kodzhimatov, Ozodbek Ashurmetov. Prenylated benzophenones and xanthones from Hypericum scabrum. Journal of natural products. 2004 Nov; 67(11):1870-5. doi: 10.1021/np040024+. [PMID: 15568778]
  • Maria Couladis, Paraskevi Baziou, Eumorfia Verykokidou, Anargyros Loukis. Antioxidant activity of polyphenols from Hypericum triquetrifolium Turra. Phytotherapy research : PTR. 2002 Dec; 16(8):769-70. doi: 10.1002/ptr.1062. [PMID: 12458485]
  • I Rager, G Roos, P C Schmidt, K-A Kovar. Rapid quantification of constituents in St. John's wort extracts by NIR spectroscopy. Journal of pharmaceutical and biomedical analysis. 2002 May; 28(3-4):439-46. doi: 10.1016/s0731-7085(01)00602-1. [PMID: 12008122]
  • M Gobbi, M Moia, L Pirona, P Morizzoni, T Mennini. In vitro binding studies with two hypericum perforatum extracts--hyperforin, hypericin and biapigenin--on 5-HT6, 5-HT7, GABA(A)/benzodiazepine, sigma, NPY-Y1/Y2 receptors and dopamine transporters. Pharmacopsychiatry. 2001 Jul; 34 Suppl 1(?):S45-8. doi: 10.1055/s-2001-15458. [PMID: 11518075]