2,3-Naphthalenedicarboxaldehyde (BioDeep_00000175144)
human metabolite blood metabolite
代谢物信息卡片
naphthalene-2,3-dicarboxaldehyde
化学式: C12H8O2 (184.0524)
中文名称: 2,3-萘基二缩醛
谱图信息:
最多检出来源 Homo sapiens(blood) 52.91%
分子结构信息
SMILES: C1=CC=C2C=C(C(=CC2=C1)C=O)C=O
InChI: InChI=1S/C12H8O2/c13-7-11-5-9-3-1-2-4-10(9)6-12(11)8-14/h1-8H
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Takuhei Yamamoto, Kousuke Sakamoto, Yukihiro Esaka, Bunji Uno. Highly Sensitive Fluorescence Detection of Daptomycin in Murine Samples through Derivatization with 2,3-Naphthalenedialdehyde.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2020 Oct; 36(10):1285-1288. doi:
10.2116/analsci.20n010. [PMID: 32378527] - Qiyang Zhang, Naveen Maddukuri, Maojun Gong. A direct and rapid method to determine cyanide in urine by capillary electrophoresis.
Journal of chromatography. A.
2015 Oct; 1414(?):158-62. doi:
10.1016/j.chroma.2015.08.050. [PMID: 26342870] - Ayumi Tabara, Takashi Kaneta. Discrimination of glycoproteins via two-color laser-induced fluorescence detection coupled with postcolumn derivatization in capillary electrophoresis.
Electrophoresis.
2013 Aug; 34(16):2316-22. doi:
10.1002/elps.201300149. [PMID: 23775479] - Deepthi Menon, Philip G Board. A fluorometric method to quantify protein glutathionylation using glutathione derivatization with 2,3-naphthalenedicarboxaldehyde.
Analytical biochemistry.
2013 Feb; 433(2):132-6. doi:
10.1016/j.ab.2012.10.009. [PMID: 23072983] - Yu Hui, Michael Wong, Joo-oll Kim, Jennifer Love, David M Ansley, David D Y Chen. A new derivatization method coupled with LC-MS/MS to enable baseline separation and quantification of dimethylarginines in human plasma from patients to receive on-pump CABG surgery.
Electrophoresis.
2012 Jul; 33(12):1911-20. doi:
10.1002/elps.201100536. [PMID: 22740479] - Thomas H Linz, Christa M Snyder, Susan M Lunte. Optimization of the separation of NDA-derivatized methylarginines by capillary and microchip electrophoresis.
Journal of laboratory automation.
2012 Feb; 17(1):24-31. doi:
10.1177/2211068211424551. [PMID: 22357605] - Einar J Stauber, Petrissa Kuczka, Maike van Ohlen, Birgit Vogt, Tim Janowitz, Markus Piotrowski, Till Beuerle, Ute Wittstock. Turning the 'mustard oil bomb' into a 'cyanide bomb': aromatic glucosinolate metabolism in a specialist insect herbivore.
PloS one.
2012; 7(4):e35545. doi:
10.1371/journal.pone.0035545. [PMID: 22536404] - Neal S Gould, Elysia Min, Steve Gauthier, Richard J Martin, Brian J Day. Lung glutathione adaptive responses to cigarette smoke exposure.
Respiratory research.
2011 Oct; 12(?):133. doi:
10.1186/1465-9921-12-133. [PMID: 21982222] - Takashi Kaneta, Takehito Ogura, Totaro Imasaka. Analysis of proteins in biological samples by capillary sieving electrophoresis with postcolumn derivatization/laser-induced fluorescence detection.
Electrophoresis.
2011 Apr; 32(9):1061-7. doi:
10.1002/elps.201000488. [PMID: 21449073] - Najoua Guelzim, Jean-François Huneau, Véronique Mathé, Annie Quignard-Boulangé, Pascal G Martin, Daniel Tomé, Dominique Hermier. Consequences of PPAR(α) Invalidation on Glutathione Synthesis: Interactions with Dietary Fatty Acids.
PPAR research.
2011; 2011(?):256186. doi:
10.1155/2011/256186. [PMID: 21915176] - Denny Proksch, Jan Jasper Klein, Christoph Arenz. Potent inhibition of Acid ceramidase by novel B-13 analogues.
Journal of lipids.
2011; 2011(?):971618. doi:
10.1155/2011/971618. [PMID: 21490813] - Ying Chen, Jianhua Zhang, Lan Zhang, Guonan Chen. Separation of dipeptides with two chiral centers using 2-hydroxypropyl-beta-CD-modified MEKC.
Electrophoresis.
2010 May; 31(9):1493-7. doi:
10.1002/elps.200900592. [PMID: 20376812] - Hyesung Lee, Moon-Jeong Chang, Sun-Hee Kim. Effects of poly-gamma-glutamic acid on serum and brain concentrations of glutamate and GABA in diet-induced obese rats.
Nutrition research and practice.
2010 Feb; 4(1):23-9. doi:
10.4162/nrp.2010.4.1.23. [PMID: 20198205] - Li-Yao Zhang, Meng-Xiang Sun. Fast determination of glutathione by capillary electrophoresis with fluorescence detection using beta-cyclodextrin as modifier.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Dec; 877(31):4051-4. doi:
10.1016/j.jchromb.2009.10.001. [PMID: 19858002] - Liliana J G Silva, Celeste M Lino, Angelina Pena. Sphinganine-sphingosine ratio in urine from two Portuguese populations as biomarker to fumonisins exposure.
Toxicon : official journal of the International Society on Toxinology.
2009 Sep; 54(4):390-8. doi:
10.1016/j.toxicon.2009.05.011. [PMID: 19477192] - Wei-Lung Tseng, Chih-Yao Hsu, Tsung-Han Wu, Shiou-Wen Huang, Ming-Mu Hsieh. Highly sensitive detection of chiral amino acids by CE based on on-line stacking techniques.
Electrophoresis.
2009 Jul; 30(14):2558-64. doi:
10.1002/elps.200800765. [PMID: 19639576] - Xingxuan He, Chien-Ling Huang, Edward H Schuchman. Quantitative analysis of sphingosine-1-phosphate by HPLC after napthalene-2,3-dicarboxaldehyde (NDA) derivatization.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Apr; 877(10):983-90. doi:
10.1016/j.jchromb.2009.02.048. [PMID: 19285924] - Tai-Chia Chiu, Wu-Chun Tu, Huan-Tsung Chang. Stacking and separation of protein derivatives of naphthalene-2,3-dicarboxaldehyde by CE with light-emitting diode induced fluorescence detection.
Electrophoresis.
2008 Jan; 29(2):433-40. doi:
10.1002/elps.200700315. [PMID: 18064734] - Li-Yao Zhang, Meng-Xiang Sun. Capillary electrophoresis of phosphorylated amino acids with fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Nov; 859(1):30-6. doi:
10.1016/j.jchromb.2007.09.022. [PMID: 17923447] - Xiupei Yang, Hongyan Yuan, Chunling Wang, Xiaodong Su, Li Hu, Dan Xiao. Determination of penicillamine in pharmaceuticals and human plasma by capillary electrophoresis with in-column fiber optics light-emitting diode induced fluorescence detection.
Journal of pharmaceutical and biomedical analysis.
2007 Oct; 45(2):362-6. doi:
10.1016/j.jpba.2007.05.017. [PMID: 17606355] - Qinglei Yu, Shulin Zhao, Fanggui Ye, Shuting Li. Determination of octopamine in human plasma by capillary electrophoresis with optical fiber light-emitting diode-induced fluorescence detection.
Analytical biochemistry.
2007 Oct; 369(2):187-91. doi:
10.1016/j.ab.2007.06.014. [PMID: 17632069] - José Fernando Huertas-Pérez, Michal Heger, Henk Dekker, Hans Krabbe, Jan Lankelma, Freek Ariese. Simple, rapid, and sensitive liquid chromatography-fluorescence method for the quantification of tranexamic acid in blood.
Journal of chromatography. A.
2007 Jul; 1157(1-2):142-50. doi:
10.1016/j.chroma.2007.04.067. [PMID: 17532325] - Po-Ling Chang, Kun-Hong Lee, Cho-Chun Hu, Huan-Tsung Chang. CE with sequential light-emitting diode-induced fluorescence and electro-chemiluminescence detections for the determination of amino acids and alkaloids.
Electrophoresis.
2007 Apr; 28(7):1092-9. doi:
10.1002/elps.200600546. [PMID: 17330227] - Bryan H Huynh, Barbara A Fogarty, Pradyot Nandi, Susan M Lunte. A microchip electrophoresis device with on-line microdialysis sampling and on-chip sample derivatization by naphthalene 2,3-dicarboxaldehyde/2-mercaptoethanol for amino acid and peptide analysis.
Journal of pharmaceutical and biomedical analysis.
2006 Nov; 42(5):529-34. doi:
10.1016/j.jpba.2006.05.014. [PMID: 16829012] - Chunling Wang, Shulin Zhao, Hongyan Yuan, Dan Xiao. Determination of excitatory amino acids in biological fluids by capillary electrophoresis with optical fiber light-emitting diode induced fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 Apr; 833(2):129-34. doi:
10.1016/j.jchromb.2006.01.013. [PMID: 16500157] - Chih-Lin Su, Wei-Lung Tseng. Selective detection of homocysteine by laser desorption/ionization mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2006; 20(22):3303-8. doi:
10.1002/rcm.2736. [PMID: 17044125] - Li-Yao Zhang, Meng-Xiang Sun. Field-amplified sample injection and in-capillary derivatization for sensitivity improvement of the electrophoretic determination of histamine.
Journal of chromatography. A.
2005 Dec; 1100(2):230-5. doi:
10.1016/j.chroma.2005.09.041. [PMID: 16212971] - Li-Yao Zhang, Meng-Xiang Sun. Selective determination of gamma-aminobutyric acid, glutamate and alanine by mixed micellar electrokinetic chromatography and fluorescence detection.
Journal of chromatography. A.
2005 Nov; 1095(1-2):185-8. doi:
10.1016/j.chroma.2005.09.050. [PMID: 16221476] - Gamze Kavran-Belin, Serge Rudaz, Jean-Luc Veuthey. Enantioseparation of baclofen with highly sulfated beta-cyclodextrin by capillary electrophoresis with laser-induced fluorescence detection.
Journal of separation science.
2005 Nov; 28(16):2187-92. doi:
10.1002/jssc.200500100. [PMID: 16318216] - Takao Ueno, Mitsuru Tanaka, Toshiro Matsui, Kiyoshi Matsumoto. Determination of antihypertensive small peptides, Val-Tyr and Ile-Val-Tyr, by fluorometric high-performance liquid chromatography combined with a double heart-cut column-switching technique.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2005 Aug; 21(8):997-1000. doi:
10.2116/analsci.21.997. [PMID: 16122175] - Xingxuan He, Arie Dagan, Shimon Gatt, Edward H Schuchman. Simultaneous quantitative analysis of ceramide and sphingosine in mouse blood by naphthalene-2,3-dicarboxyaldehyde derivatization after hydrolysis with ceramidase.
Analytical biochemistry.
2005 May; 340(1):113-22. doi:
10.1016/j.ab.2005.01.058. [PMID: 15802137] - Hsuan-Ming Huang, Cheng-Huang Lin. Methanol plug assisted sweeping-micellar electrokinetic chromatography for the determination of dopamine in urine by violet light emitting diode-induced fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Feb; 816(1-2):113-9. doi:
10.1016/j.jchromb.2004.11.018. [PMID: 15664341] - Li-Yao Zhang, Meng-Xiang Sun. Determination of histamine and histidine by capillary zone electrophoresis with pre-column naphthalene-2,3-dicarboxaldehyde derivatization and fluorescence detection.
Journal of chromatography. A.
2004 Jun; 1040(1):133-40. doi:
10.1016/j.chroma.2004.03.051. [PMID: 15248433] - Maurizio Marra, Anna Rita Bonfigli, Roberto Testa, Ivano Testa, Anna Gambini, Gilberto Coppa. High-performance liquid chromatographic assay of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine in human plasma by derivatization with naphthalene-2,3-dicarboxaldehyde.
Analytical biochemistry.
2003 Jul; 318(1):13-7. doi:
10.1016/s0003-2697(03)00157-x. [PMID: 12782025] - Jerry Z Yang, K Chad Bastian, Randy D Moore, John F Stobaugh, Ronald T Borchardt. Quantitative analysis of a model opioid peptide and its cyclic prodrugs in rat plasma using high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2002 Nov; 780(2):269-81. doi:
10.1016/s1570-0232(02)00536-6. [PMID: 12401352] - S Zhao, Y M Liu. Electrophoretic separation of tryptophan enantiomers in biological samples.
Electrophoresis.
2001 Aug; 22(13):2769-74. doi:
10.1002/1522-2683(200108)22:13<2769::aid-elps2769>3.0.co;2-h. [PMID: 11545406] - M T Chiang, S Y Chang, C W Whang. Chiral analysis of baclofen by alpha-cyclodextrin-modified capillary electrophoresis and laser-induced fluorescence detection.
Electrophoresis.
2001 Jan; 22(1):123-7. doi:
10.1002/1522-2683(200101)22:1<123::aid-elps123>3.0.co;2-4. [PMID: 11197160] - A Capdevila, C Wagner. Measurement of plasma S-adenosylmethionine and S-adenosylhomocysteine as their fluorescent isoindoles.
Analytical biochemistry.
1998 Nov; 264(2):180-4. doi:
10.1006/abio.1998.2839. [PMID: 9866680] - E J Eisenberg, K C Cundy. High-performance liquid chromatographic determination of GS4071, a potent inhibitor of influenza neuraminidase, in plasma by precolumn fluorescence derivatization with naphthalenedialdehyde.
Journal of chromatography. B, Biomedical sciences and applications.
1998 Sep; 716(1-2):267-73. doi:
10.1016/s0378-4347(98)00268-0. [PMID: 9824240] - M L Kilkenny, M Slavik, C M Riley, J F Stobaugh. Plasma analysis of alpha-difluoromethylornithine using pre-column derivatization with naphthalene-2,3-dicarboxaldehyde/CN and multidimensional chromatography.
Journal of pharmaceutical and biomedical analysis.
1998 Sep; 17(6-7):1205-13. doi:
10.1016/s0731-7085(98)00086-7. [PMID: 9884211] - T Matsui, H Matsufuji, T Kawasaki, Y Osajima. Determination of endogenous peptides with in vitro ACE inhibitory activity in normotensive human plasma by the fluorometric HPLC method.
Bioscience, biotechnology, and biochemistry.
1997 Jun; 61(6):1052-4. doi:
10.1271/bbb.61.1052. [PMID: 9214772] - W F Kline, B K Matuszewski, J Y Hsieh. Determination of a cyclic heptapeptide, a novel fibrinogen receptor antagonist, in human plasma by high-performance liquid chromatography with automated pre-column derivatization, column switching and fluorescence detection.
Journal of chromatography.
1992 Jul; 578(1):31-7. doi:
10.1016/0378-4347(92)80221-b. [PMID: 1328269] - W F Kline, B K Matuszewski, W F Bayne. Determination of 4-amino-1-hydroxybutane-1,1-bisphosphonic acid in urine by automated pre-column derivatization with 2,3-naphthalene dicarboxyaldehyde and high-performance liquid chromatography with fluorescence detection.
Journal of chromatography.
1990 Dec; 534(?):139-49. doi:
10.1016/s0378-4347(00)82156-8. [PMID: 2094701] - P J Kwakman, H Koelewijn, I Kool, U A Brinkman, G J De Jong. Naphthalene- and anthracene-2,3-dialdehyde as precolumn labelling reagents for primary amines using reversed- and normal-phase liquid chromatography with peroxyoxalate chemiluminescence detection.
Journal of chromatography.
1990 Jul; 511(?):155-66. doi:
10.1016/s0021-9673(01)93281-9. [PMID: 2120277] - L A Sprancmanis, C M Riley, J F Stobaugh. Determination of the anticancer drug, 15-deoxyspergualin, in plasma ultrafiltrate by liquid chromatography and precolumn derivatization with naphthalene-2,3-dicarboxaldehyde/cyanide.
Journal of pharmaceutical and biomedical analysis.
1990; 8(2):165-75. doi:
10.1016/0731-7085(90)80024-j. [PMID: 2094416] - P de Montigny, C M Riley, L A Sternson, J F Stobaugh. Fluorogenic derivatization of peptides with naphthalene-2,3-dicarboxaldehyde/cyanide: optimization of yield and application in the determination of leucine-enkephalin spiked human plasma samples.
Journal of pharmaceutical and biomedical analysis.
1990; 8(5):419-29. doi:
10.1016/0731-7085(90)80070-6. [PMID: 2081203] - T Kawasaki, T Higuchi, K Imai, O S Wong. Determination of dopamine, norepinephrine, and related trace amines by prechromatographic derivatization with naphthalene-2,3-dicarboxaldehyde.
Analytical biochemistry.
1989 Aug; 180(2):279-85. doi:
10.1016/0003-2697(89)90431-4. [PMID: 2510545] - T Miura, M Kashiwamura, M Kimura. A fluorometric method for the specific determination of serum arginine with 2,3-naphthalenedicarbaldehyde.
Analytical biochemistry.
1984 Jun; 139(2):432-7. doi:
10.1016/0003-2697(84)90030-7. [PMID: 6476380] - J P Malaspina, J Fourche, H Jensen, E Neuzil. [Colorimetric determination of cholesterol in biological fluids using 2,3-naphthalenedicarboxaldehyde (author's transl)].
Annales de biologie clinique.
1980; 38(4):207-13. doi:
NULL. [PMID: 7446873]
