7-Hydroxyflumequine (BioDeep_00000175099)

   

human metabolite blood metabolite


代谢物信息卡片


7-fluoro-10-hydroxy-12-methyl-4-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid

化学式: C14H12FNO4 (277.0750324)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC(C2=CC(=CC3=C2N1C=C(C3=O)C(=O)O)F)O
InChI: InChI=1S/C14H12FNO4/c1-6-2-11(17)8-3-7(15)4-9-12(8)16(6)5-10(13(9)18)14(19)20/h3-6,11,17H,2H2,1H3,(H,19,20)



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • J M Delmas, A M Chapel, P Sanders. Determination of flumequine and 7-hydroxyflumequine in plasma of sheep by high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications. 1998 Aug; 712(1-2):263-8. doi: 10.1016/s0378-4347(98)00159-5. [PMID: 9698250]
  • J M Delmas, A M Chapel, P Sanders. Determination of residues of flumequine and 7-hydroxyflumequine in edible sheep tissues by liquid chromatography with fluorimetric and ultraviolet detection. Journal of AOAC International. 1998 May; 81(3):519-27. doi: 10.1093/jaoac/81.3.519. [PMID: 9606916]
  • J M Delmas, A M Chapel, V Gaudin, P Sanders. Pharmacokinetics of flumequine in sheep after intravenous and intramuscular administration: bioavailability and tissue residue studies. Journal of veterinary pharmacology and therapeutics. 1997 Aug; 20(4):249-57. doi: 10.1046/j.1365-2885.1997.00067.x. [PMID: 9280363]
  • M J Royer-Morrot, A Gérard, A Zhiri, F Schooneman, J B Dureux, R J Royer. Effect of plasma exchange on flumequine pharmacokinetics: comparison with control kinetics. Therapeutic drug monitoring. 1991 Jul; 13(4):296-303. doi: 10.1097/00007691-199107000-00003. [PMID: 1780960]
  • D Decolin, A Nicolas, G Siest. Determination of flumequine and its 7-hydroxy metabolite by reversed-phase high-performance liquid chromatography. Journal of chromatography. 1987 Mar; 414(2):499-503. doi: 10.1016/0378-4347(87)80080-4. [PMID: 3571419]
  • D Schuppan, L I Harrison, S R Rohlfing, H L Miller, M L Funk, C S Hansen, R E Ober. Plasma and urine levels of flumequine and 7-hydroxyflumequine following single and multiple oral dosing. The Journal of antimicrobial chemotherapy. 1985 Mar; 15(3):337-43. doi: 10.1093/jac/15.3.337. [PMID: 3997708]
  • L I Harrison, D Schuppan, S R Rohlfing, A R Hansen, C S Hansen, M L Funk, S H Collins, R E Ober. Determination of flumequine and a hydroxy metabolite in biological fluids by high-pressure liquid chromatographic, fluorometric, and microbiological methods. Antimicrobial agents and chemotherapy. 1984 Mar; 25(3):301-5. doi: 10.1128/aac.25.3.301. [PMID: 6372680]