Octadeca-6,9,12-trienoic acid (BioDeep_00000174975)

   

human metabolite blood metabolite natural product


代谢物信息卡片


octadeca-6,9,12-trienoic acid

化学式: C18H30O2 (278.2246)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 4.78%

分子结构信息

SMILES: CCCCCC=CCC=CCC=CCCCCC(=O)O
InChI: InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10,12-13H,2-5,8,11,14-17H2,1H3,(H,19,20)



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

43 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • O Ya Lukivskaya, E Naruta, V Sadovnichy, S Kirko, V U Buko. Reversal of experimental ethanol-induced liver steatosis by borage oil. Phytotherapy research : PTR. 2012 Nov; 26(11):1626-31. doi: 10.1002/ptr.4621. [PMID: 22359349]
  • Simon J Evans, Masoud Kamali, Alan R Prossin, Gloria J Harrington, Vicki L Ellingrod, Melvin G McInnis, Charles F Burant. Association of plasma ω-3 and ω-6 lipids with burden of disease measures in bipolar subjects. Journal of psychiatric research. 2012 Nov; 46(11):1435-41. doi: 10.1016/j.jpsychires.2012.07.016. [PMID: 22884424]
  • Aranya Manosroi, Warintorn Ruksiriwanich, Masahiko Abe, Worapaka Manosroi, Jiradej Manosroi. Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2012 Jun; 81(2):303-13. doi: 10.1016/j.ejpb.2012.03.014. [PMID: 22490981]
  • Tomáš Řezanka, Jaromír Lukavský, Lucie Siristova, Karel Sigler. Regioisomer separation and identification of triacylglycerols containing vaccenic and oleic acids, and α- and γ-linolenic acids, in thermophilic cyanobacteria Mastigocladus laminosus and Tolypothrix sp. Phytochemistry. 2012 Jun; 78(?):147-55. doi: 10.1016/j.phytochem.2012.02.028. [PMID: 22445652]
  • Patrick Tso, Jody Caldwell, Dana Lee, Gregory P Boivin, Stephen J DeMichele. Comparison of growth, serum biochemistries and n-6 fatty acid metabolism in rats fed diets supplemented with high-gamma-linolenic acid safflower oil or borage oil for 90 days. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2012 Jun; 50(6):1911-9. doi: 10.1016/j.fct.2012.01.001. [PMID: 22265940]
  • Luciano Trevizan, Alexandre de Mello Kessler, J Thomas Brenna, Peter Lawrence, Mark K Waldron, John E Bauer. Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets. Lipids. 2012 Apr; 47(4):413-23. doi: 10.1007/s11745-011-3651-0. [PMID: 22249937]
  • Cory L Nykiforuk, Christine Shewmaker, Indra Harry, Olga P Yurchenko, Mei Zhang, Catherine Reed, Gunamani S Oinam, Steve Zaplachinski, Ana Fidantsef, Joseph G Boothe, Maurice M Moloney. High level accumulation of gamma linolenic acid (C18:3Δ6.9,12 cis) in transgenic safflower (Carthamus tinctorius) seeds. Transgenic research. 2012 Apr; 21(2):367-81. doi: 10.1007/s11248-011-9543-5. [PMID: 21853296]
  • M J de la Torre Aguilar, A Cox Belmonte, M D Mesa-García, J L Pérez Navero, M M Gil-Campos. [Plasma fatty acids profile in paediatric cancer patients]. Nutricion hospitalaria. 2012 Mar; 27(2):617-22. doi: 10.1590/s0212-16112012000200040. [PMID: 22732992]
  • Xiaoping Wang, Huanping Lin, Yan Gu. Multiple roles of dihomo-γ-linolenic acid against proliferation diseases. Lipids in health and disease. 2012 Feb; 11(?):25. doi: 10.1186/1476-511x-11-25. [PMID: 22333072]
  • Pérola Ribeiro, Fernanda Daniela Fernandes Carvalho, Amanda de Amaro Abreu, Marcela de Toledo Sant'anna, Rosemary Joana de Lima, Patrícia de Oliveira Carvalho. Effect of fish oil supplementation in pregnancy on the fatty acid composition of erythrocyte phospholipids and breast milk lipids. International journal of food sciences and nutrition. 2012 Feb; 63(1):36-40. doi: 10.3109/09637486.2011.593714. [PMID: 21707451]
  • Sabrina Viau, Laurent Leclère, Bénédicte Buteau, Stéphane Grégoire, Niyazi Acar, Alain Bron, Catherine P Creuzot-Garcher, Lionel Bretillon, Corinne Joffre. Polyunsaturated fatty acids induce modification in the lipid composition and the prostaglandin production of the conjunctival epithelium cells. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 2012 Feb; 250(2):211-22. doi: 10.1007/s00417-011-1801-y. [PMID: 21894532]
  • Cornelia Enzenbach, Janine Kröger, Vera Zietemann, Eugène H J M Jansen, Andreas Fritsche, Frank Döring, Heiner Boeing, Matthias B Schulze. Erythrocyte membrane phospholipid polyunsaturated fatty acids are related to plasma C-reactive protein and adiponectin in middle-aged German women and men. European journal of nutrition. 2011 Dec; 50(8):625-36. doi: 10.1007/s00394-011-0169-4. [PMID: 21301856]
  • Negin Fasih Ramandi, Nahid Mashkouri Najafi, Farhad Raofie, Ensieh Ghasemi. Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. Journal of food science. 2011 Nov; 76(9):C1262-6. doi: 10.1111/j.1750-3841.2011.02394.x. [PMID: 22416687]
  • Bakhtyar Tartibian, Behzad Hajizadeh Maleki, Jill Kanaley, Karim Sadeghi. Long-term aerobic exercise and omega-3 supplementation modulate osteoporosis through inflammatory mechanisms in post-menopausal women: a randomized, repeated measures study. Nutrition & metabolism. 2011 Oct; 8(?):71. doi: 10.1186/1743-7075-8-71. [PMID: 21999620]
  • Todd W Rice, Arthur P Wheeler, B Taylor Thompson, Bennett P deBoisblanc, Jay Steingrub, Peter Rock. Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. JAMA. 2011 Oct; 306(14):1574-81. doi: 10.1001/jama.2011.1435. [PMID: 21976613]
  • Petra Meeuwse, Johannes Tramper, Arjen Rinzema. Modeling lipid accumulation in oleaginous fungi in chemostat cultures. II: Validation of the chemostat model using yeast culture data from literature. Bioprocess and biosystems engineering. 2011 Oct; 34(8):951-61. doi: 10.1007/s00449-011-0546-7. [PMID: 21516366]
  • Petra Meeuwse, Johannes Tramper, Arjen Rinzema. Modeling lipid accumulation in oleaginous fungi in chemostat cultures: I. Development and validation of a chemostat model for Umbelopsis isabellina. Bioprocess and biosystems engineering. 2011 Oct; 34(8):939-49. doi: 10.1007/s00449-011-0545-8. [PMID: 21538015]
  • Undurti N Das, N Madhavi. Effect of polyunsaturated fatty acids on drug-sensitive and resistant tumor cells in vitro. Lipids in health and disease. 2011 Sep; 10(?):159. doi: 10.1186/1476-511x-10-159. [PMID: 21917129]
  • Murat Kanbur, Gökhan Eraslan, Zeynep Soyer Sarıca, Oznur Aslan. The effects of evening primrose oil on lipid peroxidation induced by subacute aflatoxin exposure in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2011 Sep; 49(9):1960-4. doi: 10.1016/j.fct.2011.05.006. [PMID: 21600263]
  • Gary J Macfarlane, Ashraf El-Metwally, Vijitha De Silva, Edzard Ernst, Gillian L Dowds, Robert J Moots. Evidence for the efficacy of complementary and alternative medicines in the management of rheumatoid arthritis: a systematic review. Rheumatology (Oxford, England). 2011 Sep; 50(9):1672-83. doi: 10.1093/rheumatology/ker119. [PMID: 21652584]
  • Simone Coghetto Acedo, Erica Martins Ferreira Gotardo, Janilda Martins Lacerda, Caroline Candida de Oliveira, Patrícia de Oliveira Carvalho, Alessandra Gambero. Perinodal adipose tissue and mesenteric lymph node activation during reactivated TNBS-colitis in rats. Digestive diseases and sciences. 2011 Sep; 56(9):2545-52. doi: 10.1007/s10620-011-1644-8. [PMID: 21380759]
  • T Laho, Z Váradyová, K Mihaliková, S Kišidayová, Z Adamechová, M Certík, D Jalč. Effects of prefermented cereal-derived substrates (ground barley and rye bran) enriched with fungal γ-linolenic acid on rumen fermentation parameters and lipid metabolism in vitro. Journal of applied microbiology. 2011 Sep; 111(3):537-46. doi: 10.1111/j.1365-2672.2011.05073.x. [PMID: 21672096]
  • Jun Zhang, Jessica A Grieger, Penny M Kris-Etherton, Jerry T Thompson, Peter J Gillies, Jennifer A Fleming, John P Vanden Heuvel. Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells. Nutrition & metabolism. 2011 Aug; 8(?):61. doi: 10.1186/1743-7075-8-61. [PMID: 21871057]
  • Ramez Alhazzaa, Andrew R Bridle, Peter D Nichols, Chris G Carter. Up-regulated desaturase and elongase gene expression promoted accumulation of polyunsaturated fatty acid (PUFA) but not long-chain PUFA in Lates calcarifer, a tropical euryhaline fish, fed a stearidonic acid- and γ-linoleic acid-enriched diet. Journal of agricultural and food chemistry. 2011 Aug; 59(15):8423-34. doi: 10.1021/jf201871w. [PMID: 21707030]
  • Christine Dawczynski, Ursula Hackermeier, Martin Viehweger, Rainer Stange, Monika Springer, Gerhard Jahreis. Incorporation of n-3 PUFA and γ-linolenic acid in blood lipids and red blood cell lipids together with their influence on disease activity in patients with chronic inflammatory arthritis--a randomized controlled human intervention trial. Lipids in health and disease. 2011 Aug; 10(?):130. doi: 10.1186/1476-511x-10-130. [PMID: 21816071]
  • Qing Chen, Jonathan Nimal, Wanli Li, Xia Liu, Wenguang Cao. Delta-6 desaturase from borage converts linoleic acid to gamma-linolenic acid in HEK293 cells. Biochemical and biophysical research communications. 2011 Jul; 410(3):484-8. doi: 10.1016/j.bbrc.2011.06.003. [PMID: 21679695]
  • Herbert P Wiedemann. Fish oil is not the fix for acute lung injury. Critical care medicine. 2011 Jul; 39(7):1829-30. doi: 10.1097/ccm.0b013e31821b82bb. [PMID: 21685749]
  • Hongjun Hu, Yeguang Li, Chuntao Yin, Yexin Ouyang. Isolation and characterization of a mesophilic Arthrospira maxima strain capable of producing docosahexaenoic acid. Journal of microbiology and biotechnology. 2011 Jul; 21(7):697-702. doi: 10.4014/jmb.1101.12040. [PMID: 21791955]
  • Gisela Irmisch, Jacqueline Hoeppner, Johannes Thome, Joerg Richter, Anja Fernow, Emil C Reisinger, Michael Lafrenz, Micha Loebermann. Serum fatty acids, antioxidants, and treatment response in hepatitis C infection: greater polyunsaturated fatty acid and antioxidant levels in hepatitis C responders. Journal of clinical lipidology. 2011 Jul; 5(4):288-93. doi: 10.1016/j.jacl.2011.04.005. [PMID: 21784374]
  • Fabian Bumbak, Stella Cook, Vilém Zachleder, Silas Hauser, Karin Kovar. Best practices in heterotrophic high-cell-density microalgal processes: achievements, potential and possible limitations. Applied microbiology and biotechnology. 2011 Jul; 91(1):31-46. doi: 10.1007/s00253-011-3311-6. [PMID: 21567179]
  • Sawsan A Zaitone, Yasser M Moustafa, Sarah M Mosaad, Naglaa F El-Orabi. Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. Journal of cardiovascular pharmacology. 2011 Jul; 58(1):72-9. doi: 10.1097/fjc.0b013e31821c8353. [PMID: 21499116]
  • Shao Li, Bo Zhang, Ningbo Zhang. Network target for screening synergistic drug combinations with application to traditional Chinese medicine. BMC systems biology. 2011 Jun; 5 Suppl 1(?):S10. doi: 10.1186/1752-0509-5-s1-s10. [PMID: 21689469]
  • Brian S Rett, Jay Whelan. Increasing dietary linoleic acid does not increase tissue arachidonic acid content in adults consuming Western-type diets: a systematic review. Nutrition & metabolism. 2011 Jun; 8(?):36. doi: 10.1186/1743-7075-8-36. [PMID: 21663641]
  • Wafa'a A Al-Khamees, Michael D Schwartz, Saleh Alrashdi, Adam D Algren, Brent W Morgan. Status epilepticus associated with borage oil ingestion. Journal of medical toxicology : official journal of the American College of Medical Toxicology. 2011 Jun; 7(2):154-7. doi: 10.1007/s13181-011-0135-9. [PMID: 21387119]
  • Srinivas Belide, Luch Hac, Surinder P Singh, Allan G Green, Craig C Wood. Agrobacterium-mediated transformation of safflower and the efficient recovery of transgenic plants via grafting. Plant methods. 2011 May; 7(?):12. doi: 10.1186/1746-4811-7-12. [PMID: 21595986]
  • Rasika A Mathias, Susan Sergeant, Ingo Ruczinski, Dara G Torgerson, Christina E Hugenschmidt, Meghan Kubala, Dhananjay Vaidya, Bhoom Suktitipat, Julie T Ziegler, Priscilla Ivester, Douglas Case, Lisa R Yanek, Barry I Freedman, Megan E Rudock, Kathleen C Barnes, Carl D Langefeld, Lewis C Becker, Donald W Bowden, Diane M Becker, Floyd H Chilton. The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans. BMC genetics. 2011 May; 12(?):50. doi: 10.1186/1471-2156-12-50. [PMID: 21599946]
  • Undurti N Das. Lipoxins as biomarkers of lupus and other inflammatory conditions. Lipids in health and disease. 2011 May; 10(?):76. doi: 10.1186/1476-511x-10-76. [PMID: 21569625]
  • Afaf K El-Ansary, Abir G Ben Bacha, Layla Y Al-Ayahdi. Plasma fatty acids as diagnostic markers in autistic patients from Saudi Arabia. Lipids in health and disease. 2011 Apr; 10(?):62. doi: 10.1186/1476-511x-10-62. [PMID: 21510882]
  • Denis Khnykin, Jeffrey H Miner, Frode Jahnsen. Role of fatty acid transporters in epidermis: Implications for health and disease. Dermato-endocrinology. 2011 Apr; 3(2):53-61. doi: 10.4161/derm.3.2.14816. [PMID: 21695012]
  • Melainie Cameron, Joel J Gagnier, Sigrun Chrubasik. Herbal therapy for treating rheumatoid arthritis. The Cochrane database of systematic reviews. 2011 Feb; ?(2):CD002948. doi: 10.1002/14651858.cd002948.pub2. [PMID: 21328257]
  • Nermine K Saleh, Hanan A Saleh. Olive oil effectively mitigates ovariectomy-induced osteoporosis in rats. BMC complementary and alternative medicine. 2011 Feb; 11(?):10. doi: 10.1186/1472-6882-11-10. [PMID: 21294895]
  • Leslie A Hamilton, Kimberly A Trobaugh. Acute respiratory distress syndrome: use of specialized nutrients in pediatric patients and infants. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 2011 Feb; 26(1):26-30. doi: 10.1177/0884533610392922. [PMID: 21266694]
  • Edilberto A Rocha Filho, José C Lima, João S Pinho Neto, Ulisses Montarroyos. Essential fatty acids for premenstrual syndrome and their effect on prolactin and total cholesterol levels: a randomized, double blind, placebo-controlled study. Reproductive health. 2011 Jan; 8(?):2. doi: 10.1186/1742-4755-8-2. [PMID: 21241460]
  • Lynn Htet Htet Aung, Rui-Xing Yin, Lin Miao, Xi-Jiang Hu, Ting-Ting Yan, Xiao-Li Cao, Dong-Feng Wu, Qing Li, Shang-Ling Pan, Jin-Zhen Wu. The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. Lipids in health and disease. 2011 Jan; 10(?):5. doi: 10.1186/1476-511x-10-5. [PMID: 21232153]
  • Julia Schumann, Alexander Leichtle, Joachim Thiery, Herbert Fuhrmann. Fatty acid and peptide profiles in plasma membrane and membrane rafts of PUFA supplemented RAW264.7 macrophages. PloS one. 2011; 6(8):e24066. doi: 10.1371/journal.pone.0024066. [PMID: 21887374]
  • S M Ghoreishi, E Mardani, H S Ghaziaskar. Separation of γ-linolenic and other polyunsaturated fatty acids from Boraginaceae via supercritical CO2. Journal of separation science. 2011 Jan; 34(2):233-40. doi: 10.1002/jssc.201000716. [PMID: 21246730]
  • Barbara C Olendzki, Katherine Leung, Susan Van Buskirk, George Reed, Robert B Zurier. Treatment of rheumatoid arthritis with marine and botanical oils: influence on serum lipids. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):827286. doi: 10.1155/2011/827286. [PMID: 22007257]
  • M M Ould Mohamedou, K Zouirech, M El Messal, M S El Kebbaj, A Chraibi, A Adlouni. Argan Oil Exerts an Antiatherogenic Effect by Improving Lipids and Susceptibility of LDL to Oxidation in Type 2 Diabetes Patients. International journal of endocrinology. 2011; 2011(?):747835. doi: 10.1155/2011/747835. [PMID: 22114593]
  • Yi Wang, Chengtao Hong, Chenguang Zhou, Dongmei Xu, Hai-Bin Qu. Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):363052. doi: 10.1093/ecam/nen087. [PMID: 19131395]
  • Lin Miao, Rui-Xing Yin, Dong-Feng Wu, Xiao-Li Cao, Qing Li, Xi-Jiang Hu, Ting-Ting Yan, Lynn Htet Htet Aung, De-Zhai Yang, Wei-Xiong Lin. Peroxisome proliferator-activated receptor delta +294T > C polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. Lipids in health and disease. 2010 Dec; 9(?):145. doi: 10.1186/1476-511x-9-145. [PMID: 21176135]
  • Dong-Feng Wu, Rui-Xing Yin, Lynn Htet Htet Aung, Xi-Jiang Hu, Xiao-Li Cao, Lin Miao, Qing Li, Ting-Ting Yan, Jin-Zhen Wu, Shang-Ling Pan. Polymorphism of rs1044925 in the acyl-CoA:cholesterol acyltransferase-1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. Lipids in health and disease. 2010 Dec; 9(?):139. doi: 10.1186/1476-511x-9-139. [PMID: 21143839]
  • Bhimabol Khongto, Kobkul Laoteng, Anan Tongta. Fermentation process development of recombinant Hansenula polymorpha for gamma-linolenic acid production. Journal of microbiology and biotechnology. 2010 Nov; 20(11):1555-62. doi: 10.4014/jmb.1003.03004. [PMID: 21124062]
  • Philip C Calder. Rationale and use of n-3 fatty acids in artificial nutrition. The Proceedings of the Nutrition Society. 2010 Nov; 69(4):565-73. doi: 10.1017/s0029665110000157. [PMID: 20441676]
  • Andrea Comba, Damian M Maestri, María A Berra, Carolina Paola Garcia, Undurti N Das, Aldo R Eynard, María E Pasqualini. Effect of ω-3 and ω-9 fatty acid rich oils on lipoxygenases and cyclooxygenases enzymes and on the growth of a mammary adenocarcinoma model. Lipids in health and disease. 2010 Oct; 9(?):112. doi: 10.1186/1476-511x-9-112. [PMID: 20932327]
  • Atnan Uğur, Ipek Süntar, Sinem Aslan, Ilkay Erdoğan Orhan, Murat Kartal, Nazim Sekeroğlu, Dursun Eşiyok, Bilge Sener. Variations in fatty acid compositions of the seed oil of Eruca sativa Mill. caused by different sowing periods and nitrogen forms. Pharmacognosy magazine. 2010 Oct; 6(24):305-8. doi: 10.4103/0973-1296.71801. [PMID: 21120033]
  • Gisela Irmisch, Detlef Schlaefke, Joerg Richter. Zinc and fatty acids in depression. Neurochemical research. 2010 Sep; 35(9):1376-83. doi: 10.1007/s11064-010-0194-3. [PMID: 20524151]
  • Jing Li, Ryu Wakui, Masanori Horie, Yoshichika Nishimura, Yoshihide Nishiyama, Yasunori Ikeno, Shin-ichi Tebayashi, Chul-Sa Kim. Feeding stimulant in Cinnamomum camphora for the common bluebottle, Graphium sarpedon nipponum (Lepidoptera: Papilionidae). Zeitschrift fur Naturforschung. C, Journal of biosciences. 2010 Sep; 65(9-10):571-6. doi: 10.1515/znc-2010-9-1007. [PMID: 21138058]
  • Shinji Itoh, Akinobu Taketomi, Norifumi Harimoto, Eiji Tsujita, Tatsuya Rikimaru, Ken Shirabe, Mitsuo Shimada, Yoshihiko Maehara. Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines. Journal of clinical biochemistry and nutrition. 2010 Jul; 47(1):81-90. doi: 10.3164/jcbn.10-24. [PMID: 20664735]
  • Undurti N Das. Polyunsaturated fatty acids and atopic dermatitis. Nutrition (Burbank, Los Angeles County, Calif.). 2010 Jul; 26(7-8):719-20. doi: 10.1016/j.nut.2010.03.008. [PMID: 20579591]
  • Rachel H Foster, Gil Hardy, Raid G Alany. Borage oil in the treatment of atopic dermatitis. Nutrition (Burbank, Los Angeles County, Calif.). 2010 Jul; 26(7-8):708-18. doi: 10.1016/j.nut.2009.10.014. [PMID: 20579590]
  • Zhao Fa-lin, Wu Zhen-yu, Hou Yan, Zhang Tao, Li Kang. Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. Phytotherapy research : PTR. 2010 Jun; 24 Suppl 2(?):S209-13. doi: 10.1002/ptr.3092. [PMID: 20041414]
  • Hua Wang, Man Ling, Gang Xue, Fengxia Liu, Shuxian Guo. [Separation of gamma linolenic acid from evening primrose oil with urea inclusion--orthogonal experiment of optimizing technological parameters and observation of urea inclusion compound I]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 May; 35(10):1251-5. doi: 10.4268/cjcmm20101008. [PMID: 20707192]
  • Uwe Platzbecker, Carlo Aul, Gerhard Ehninger, Aristoteles Giagounidis. Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil. Annals of hematology. 2010 Apr; 89(4):427-8. doi: 10.1007/s00277-009-0824-5. [PMID: 19714330]
  • Sandhya Pruthi, Dietlind L Wahner-Roedler, Carolyn J Torkelson, Stephen S Cha, Lori S Thicke, Jennifer H Hazelton, Brent A Bauer. Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. Alternative medicine review : a journal of clinical therapeutic. 2010 Apr; 15(1):59-67. doi: ". [PMID: 20359269]
  • Takuya Suzuki, Hiroshi Hara. Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats. Nutrition & metabolism. 2010 Mar; 7(?):19. doi: 10.1186/1743-7075-7-19. [PMID: 20222989]
  • Ratana Chaiklahan, Nattayaporn Chirasuwan, Wipawan Siangdung, Kalyanee Paithoonrangsarid, Boosya Bunnag. Cultivation of Spirulina platensis using pig wastewater in a semi-continuous process. Journal of microbiology and biotechnology. 2010 Mar; 20(3):609-14. doi: 10.4014/jmb.0907.07026. [PMID: 20372035]
  • Gabriel Olveira, Casilda Olveira, Eva Acosta, Francisco Espíldora, Lourdes Garrido-Sánchez, Eva García-Escobar, Gemma Rojo-Martínez, Montserrat Gonzalo, Federico Soriguer. Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. Archivos de bronconeumologia. 2010 Feb; 46(2):70-7. doi: 10.1016/j.arbres.2009.11.001. [PMID: 20045240]
  • Etienne Pouteau, Olivier Aprikian, Catherine Grenot, Denis Reynaud, Cecil Pace-Asciak, Claude Yves Cuilleron, Eurídice Castañeda-Gutiérrez, Julie Moulin, Gregory Pescia, Carine Beysen, Scott Turner, Katherine Macé. A low alpha-linolenic intake during early life increases adiposity in the adult guinea pig. Nutrition & metabolism. 2010 Jan; 7(?):8. doi: 10.1186/1743-7075-7-8. [PMID: 20205840]
  • Robert Kleemann, Marjan van Erk, Lars Verschuren, Anita M van den Hoek, Maud Koek, Peter Y Wielinga, Annie Jie, Linette Pellis, Ivana Bobeldijk-Pastorova, Thomas Kelder, Karin Toet, Suzan Wopereis, Nicole Cnubben, Chris Evelo, Ben van Ommen, Teake Kooistra. Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance. PloS one. 2010 Jan; 5(1):e8817. doi: 10.1371/journal.pone.0008817. [PMID: 20098690]
  • Jaleh Barar, Mark Gumbleton, Masoud Asadi, Yadollah Omidi. Barrier functionality and transport machineries of human ECV304 cells. Medical science monitor : international medical journal of experimental and clinical research. 2010 Jan; 16(1):BR52-60. doi: NULL. [PMID: 20037486]
  • Vera M Barbosa, Elizabeth A Miles, Conceição Calhau, Estevão Lafuente, Philip C Calder. Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial. Critical care (London, England). 2010; 14(1):R5. doi: 10.1186/cc8844. [PMID: 20085628]
  • Geise Ribeiro, Marcel Benadiba, Denise de Oliveira Silva, Alison Colquhoun. The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. Cell biochemistry and function. 2010 Jan; 28(1):15-23. doi: 10.1002/cbf.1626. [PMID: 19927275]
  • Anna M Bakowska-Barczak, Andreas Schieber, Paul Kolodziejczyk. Characterization of Canadian black currant (Ribes nigrum L.) seed oils and residues. Journal of agricultural and food chemistry. 2009 Dec; 57(24):11528-36. doi: 10.1021/jf902161k. [PMID: 19928765]
  • David E Scheim. Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy. Lipids in health and disease. 2009 Dec; 8(?):54. doi: 10.1186/1476-511x-8-54. [PMID: 20003514]
  • Julianne Lindemann, E David Pampe, Joanna J Peterkin, Patti Orozco-Cronin, Gil Belofsky, Dean Stull. Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients. Current medical research and opinion. 2009 Dec; 25(12):2865-75. doi: 10.1185/03007990903316491. [PMID: 19811112]
  • Stylianos Fakas, Anna Makri, Maria Mavromati, Maria Tselepi, George Aggelis. Fatty acid composition in lipid fractions lengthwise the mycelium of Mortierella isabellina and lipid production by solid state fermentation. Bioresource technology. 2009 Dec; 100(23):6118-20. doi: 10.1016/j.biortech.2009.06.015. [PMID: 19574039]
  • Melainie Cameron, Joel J Gagnier, Christine V Little, Tessa J Parsons, Anette Blümle, Sigrun Chrubasik. Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis. Phytotherapy research : PTR. 2009 Dec; 23(12):1647-62. doi: 10.1002/ptr.3006. [PMID: 19941324]
  • Allen Rodgers, Sonja Lewandowski, Shameez Allie-Hamdulay, Diane Pinnock, Gretchen Baretta, Giovanni Gambaro. Evening primrose oil supplementation increases citraturia and decreases other urinary risk factors for calcium oxalate urolithiasis. The Journal of urology. 2009 Dec; 182(6):2957-63. doi: 10.1016/j.juro.2009.08.021. [PMID: 19846138]
  • M Adolph, A R Heller, T Koch, B Koletzko, K G Kreymann, K Krohn, E Pscheidl, M Senkal. Lipid emulsions - Guidelines on Parenteral Nutrition, Chapter 6. German medical science : GMS e-journal. 2009 Nov; 7(?):Doc22. doi: 10.3205/000081. [PMID: 20049078]
  • Tamara Popovic, Marija Ranic, Predrag Bulajic, Miroslav Milicevic, Aleksandra Arsic, Vesna Vucic, Marija Glibetic. Effects of n-3 Fatty Acids Supplementation on Plasma Phospholipids Fatty Acid Composition in Patients with Obstructive Jaundice- a Pilot Study. Journal of clinical biochemistry and nutrition. 2009 Nov; 45(3):370-5. doi: 10.3164/jcbn.09-54. [PMID: 19902030]
  • Brice A Labruzzo, Robert Chasuk, Susan Kendall. Which complementary therapies can help patients with PMS?. The Journal of family practice. 2009 Oct; 58(10):552-9. doi: ". [PMID: 19874736]
  • Azra Riaz, Rafeeq Alam Khan, Shahida Parveen Ahmed. Assessment of anticoagulant effect of evening primrose oil. Pakistan journal of pharmaceutical sciences. 2009 Oct; 22(4):355-9. doi: ". [PMID: 19783511]
  • Noemí Ruiz-López, Richard P Haslam, Mónica Venegas-Calerón, Tony R Larson, Ian A Graham, Johnathan A Napier, Olga Sayanova. The synthesis and accumulation of stearidonic acid in transgenic plants: a novel source of 'heart-healthy' omega-3 fatty acids. Plant biotechnology journal. 2009 Sep; 7(7):704-16. doi: 10.1111/j.1467-7652.2009.00436.x. [PMID: 19702757]
  • Nina Habermann, Bernd Christian, Bernd Luckas, Beatrice L Pool-Zobel, Elizabeth K Lund, Michael Glei. Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state. BioFactors (Oxford, England). 2009 Sep; 35(5):460-7. doi: 10.1002/biof.60. [PMID: 19798733]
  • Agnieszka Zaniewska, Malgorzata Borzym-Kluczyk, Slawomir D Szajda, Jacek Romatowski, Andrzej Gil, Malgorzata Knas, Jacek Dobryniewski, Krzysztof Zwierz. The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E. Journal of medicinal food. 2009 Aug; 12(4):914-8. doi: 10.1089/jmf.2008.0084. [PMID: 19735195]
  • Sabrina Viau, Marie-Annick Maire, Bruno Pasquis, Stéphane Grégoire, Niyazi Acar, Alain M Bron, Lionel Bretillon, Catherine P Creuzot-Garcher, Corinne Joffre. Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 2009 Aug; 247(8):1039-50. doi: 10.1007/s00417-009-1080-z. [PMID: 19415319]
  • Bogdan Smyk, Ryszard Amarowicz, Mariusz Szabelski, Ignacy Gryczynski, Zygmunt Gryczynski. Steady-state and time-resolved fluorescence studies of stripped Borage oil. Analytica chimica acta. 2009 Jul; 646(1-2):85-9. doi: 10.1016/j.aca.2009.05.007. [PMID: 19523559]
  • P Jangbua, K Laoteng, P Kitsubun, M Nopharatana, A Tongta. Gamma-linolenic acid production of Mucor rouxii by solid-state fermentation using agricultural by-products. Letters in applied microbiology. 2009 Jul; 49(1):91-7. doi: 10.1111/j.1472-765x.2009.02624.x. [PMID: 19453951]
  • Kelly L Weaver, Priscilla Ivester, Michael Seeds, L Douglas Case, Jonathan P Arm, Floyd H Chilton. Effect of dietary fatty acids on inflammatory gene expression in healthy humans. The Journal of biological chemistry. 2009 Jun; 284(23):15400-7. doi: 10.1074/jbc.m109.004861. [PMID: 19359242]
  • A Mañas-Fernández, M Vilches-Ferrón, J A Garrido-Cárdenas, E-H Belarbi, D L Alonso, F García-Maroto. Cloning and molecular characterization of the acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) gene from Echium. Lipids. 2009 Jun; 44(6):555-68. doi: 10.1007/s11745-009-3303-9. [PMID: 19412626]
  • Haitao Ge, Xiuqin Kong, Limei Shi, Lijuan Hou, Zhili Liu, Ping Li. Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. Cell biology international. 2009 Mar; 33(3):402-10. doi: 10.1016/j.cellbi.2009.01.014. [PMID: 19356705]
  • Silke De Spirt, Wilhelm Stahl, Hagen Tronnier, Helmut Sies, Marie Bejot, Jean-Marc Maurette, Ulrike Heinrich. Intervention with flaxseed and borage oil supplements modulates skin condition in women. The British journal of nutrition. 2009 Feb; 101(3):440-5. doi: 10.1017/s0007114508020321. [PMID: 18761778]
  • Melanie Wirtitsch, Erich Roth, Thomas Bachleitner-Hofmann, Barbara Wessner, Sanda Sturlan. Omega-3 and omega-6 polyunsaturated fatty acids enhance arsenic trioxide efficacy in arsenic trioxide-resistant leukemic and solid tumor cells. Oncology research. 2009; 18(2-3):83-94. doi: 10.3727/096504009789954654. [PMID: 20066898]
  • Coralie Schnebelen, Sabrina Viau, Stéphane Grégoire, Corinne Joffre, Catherine P Creuzot-Garcher, Alain M Bron, Lionel Bretillon, Niyazi Acar. Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation. Ophthalmic research. 2009; 41(4):216-24. doi: 10.1159/000217726. [PMID: 19451735]
  • Antonis Kourtidis, Rekha Srinivasaiah, Richard D Carkner, M Julia Brosnan, Douglas S Conklin. Peroxisome proliferator-activated receptor-gamma protects ERBB2-positive breast cancer cells from palmitate toxicity. Breast cancer research : BCR. 2009; 11(2):R16. doi: 10.1186/bcr2240. [PMID: 19298655]
  • Li-mei Shi, Hai-tao Ge, Xiu-qin Kong, Yuan-feng Cai, Peng-fu Li, Zhi-li Liu, Ling-dong Kong. [Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Dec; 33(23):2808-12. doi: . [PMID: 19260318]
  • Marie Zarevúcka, Zdeněk Wimmer. Plant products for pharmacology: application of enzymes in their transformations. International journal of molecular sciences. 2008 Dec; 9(12):2447-2473. doi: 10.3390/ijms9122447. [PMID: 19330086]
  • Javad Nasrollahzadeh, Fereydoun Siassi, Mahmood Doosti, Mohammad Reza Eshraghian, Fazel Shokri, Mohammad Hossein Modarressi, Javad Mohammadi-Asl, Khosro Abdi, Arash Nikmanesh, Seyed Morteza Karimian. The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. Lipids in health and disease. 2008 Nov; 7(?):45. doi: 10.1186/1476-511x-7-45. [PMID: 19014610]
  • Joan Sabater, Joan Ramon Masclans, Judit Sacanell, Pilar Chacon, Pilar Sabin, Merce Planas. Effects on hemodynamics and gas exchange of omega-3 fatty acid-enriched lipid emulsion in acute respiratory distress syndrome (ARDS): a prospective, randomized, double-blind, parallel group study. Lipids in health and disease. 2008 Oct; 7(?):39. doi: 10.1186/1476-511x-7-39. [PMID: 18947396]