5-(Hydroxymethyl)pyrrolidin-2-one (BioDeep_00000174647)
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
化学式: C5H9NO2 (115.0633254)
中文名称: 5-羟甲基-2-吡咯酮, 5-（羟甲基）吡咯烷-2-酮
谱图信息:
最多检出来源 Homo sapiens(blood) 93.75%
分子结构信息
SMILES: C1CC(=O)NC1CO
InChI: InChI=1S/C5H9NO2/c7-3-4-1-2-5(8)6-4/h4,7H,1-3H2,(H,6,8)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Michael Bader, Renate Wrbitzky, Meinolf Blaszkewicz, Michael Schäper, Christoph van Thriel. Human volunteer study on the inhalational and dermal absorption of N-methyl-2-pyrrolidone (NMP) from the vapour phase.
Archives of toxicology.
2008 Jan; 82(1):13-20. doi:
10.1007/s00204-007-0230-5. [PMID: 17721780] - Michael Bader, Renate Wrbitzky, Meinolf Blaszkewicz, Christoph van Thriel. Human experimental exposure study on the uptake and urinary elimination of N-methyl-2-pyrrolidone (NMP) during simulated workplace conditions.
Archives of toxicology.
2007 May; 81(5):335-46. doi:
10.1007/s00204-006-0161-6. [PMID: 17103143] - Stephen A Keener, Renate Wrbitzky, Michael Bader. Human volunteer study on the influence of exposure duration and dilution of dermally applied N-methyl-2-pyrrolidone (NMP) on the urinary elimination of NMP metabolites.
International archives of occupational and environmental health.
2007 Feb; 80(4):327-34. doi:
10.1007/s00420-006-0138-z. [PMID: 16897094] - Michael Bader, Wolfgang Rosenberger, Thomas Rebe, Stephen A Keener, Thomas H Brock, Hans-Jürgen Hemmerling, Renate Wrbitzky. Ambient monitoring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility.
International archives of occupational and environmental health.
2006 May; 79(5):357-64. doi:
10.1007/s00420-005-0065-4. [PMID: 16362322] - Bengt Akesson, Martin A Carnerup, Bo A G Jönsson. Evaluation of exposure biomarkers from percutaneous absorption of N-methyl-2-pyrrolidone.
Scandinavian journal of work, environment & health.
2004 Aug; 30(4):306-12. doi:
10.5271/sjweh.799. [PMID: 15458014] - B A G Jönsson, B Akesson. Human experimental exposure to N-methyl-2-pyrrolidone (NMP): toxicokinetics of NMP, 5-hydroxy- N-methyl-2-pyrrolidone, N-methylsuccinimide and 2-hydroxy- N-methylsuccinimide (2-HMSI), and biological monitoring using 2-HMSI as a biomarker.
International archives of occupational and environmental health.
2003 May; 76(4):267-74. doi:
10.1007/s00420-003-0438-5. [PMID: 12684812] - M A Carnerup, B Akesson, B A Jönsson. Determination of 5-hydroxy-N-methyl-2-pyrrolidone and 2-hydroxy-N-methylsuccinimide in human plasma and urine using liquid chromatography-electrospray tandem mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications.
2001 Sep; 761(1):107-13. doi:
10.1016/s0378-4347(01)00312-7. [PMID: 11585124]