Acridine, 3,6-bis(2-(1-piperidinyl)ethoxy)- (BioDeep_00000174082)

   

human metabolite blood metabolite


代谢物信息卡片


3,6-Bis(2-piperidinoethoxy)acridine trihydrochloride

化学式: C27H35N3O2 (433.272913)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CN1CCCCC1)OC1=CC2=NC3=C(C=CC(OCCN4CCCCC4)=C3)C=C2C=C1
InChI: InChI=1S/C27H35N3O2/c1-3-11-29(12-4-1)15-17-31-24-9-7-22-19-23-8-10-25(21-27(23)28-26(22)20-24)32-18-16-30-13-5-2-6-14-30/h7-10,19-21H,1-6,11-18H2



数据库引用编号

5 个数据库交叉引用编号

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相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

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PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • P L Black, K M McKinnon, S L Wooden, M A Ussery. Antiviral activity of biological response modifiers in a murine model of AIDS. Requirement for augmentation of natural killer cell activity and synergy with oral AZT. International journal of immunopharmacology. 1996 Nov; 18(11):633-50. doi: 10.1016/s0192-0561(96)00064-1. [PMID: 9089007]
  • R W Sidwell, J H Huffman, D L Barnard, D F Smee, R P Warren, M A Chirigos, M Kende, J Huggins. Antiviral and immunomodulating inhibitors of experimentally-induced Punta Toro virus infections. Antiviral research. 1994 Oct; 25(2):105-22. doi: 10.1016/0166-3542(94)90100-7. [PMID: 7847873]
  • S C Kunder, K M Kelly, P S Morahan. Biological response modifier-mediated resistance to herpesvirus infections requires induction of alpha/beta interferon. Antiviral research. 1993 Jun; 21(2):129-39. doi: 10.1016/0166-3542(93)90049-o. [PMID: 7687839]
  • S Grave, H Lüllmann, R Lüllmann-Rauch, G Osterkamp, M Prokopek. Induction of mucopolysaccharidosis in rats by treatment with immunostimulatory acridine derivatives. Toxicology and applied pharmacology. 1992 Jun; 114(2):215-24. doi: 10.1016/0041-008x(92)90071-y. [PMID: 1609413]
  • P S Morahan, A Pinto, D Stewart, D M Murasko, M A Brinton. Varying role of alpha/beta interferon in the antiviral efficacy of synthetic immunomodulators against Semliki Forest virus infection. Antiviral research. 1991 Mar; 15(3):241-54. doi: 10.1016/0166-3542(91)90070-8. [PMID: 1653557]
  • V Ruszala-Mallon, J Silva, A L Lumanglas, F E Durr, B S Wang. The mechanism of action of a synthetic immunomodulator, 3,6-bis(2-piperidinoethoxy)acridine trihydrochloride (CL 246,738), in natural killer cell activation in animals. International journal of immunopharmacology. 1991; 13(7):913-21. doi: 10.1016/0192-0561(91)90044-8. [PMID: 1722194]
  • M Sarzotti, D H Coppenhaver, I P Singh, J Poast, S Baron. The in vivo antiviral effect of CL246,738 is mediated by the independent induction of interferon-alpha and interferon-beta. Journal of interferon research. 1989 Jun; 9(3):265-74. doi: 10.1089/jir.1989.9.265. [PMID: 2545791]
  • F M Lueck. An overview of renal oxalosis. Nephrology nurse. 1980 May; 2(3):13-4. doi: NULL. [PMID: 6991966]