3,5-Diisopropylsalicylic acid (BioDeep_00000174067)
human metabolite blood metabolite
代谢物信息卡片
化学式: C13H18O3 (222.1256)
中文名称: 3,5-二异丙基邻羟基苯甲酸, 3,5-二异丙基水杨酸
谱图信息:
最多检出来源 Mus musculus(blood) 100%
分子结构信息
SMILES: CC(C)C1=CC(=C(C(=C1)C(=O)O)O)C(C)C
InChI: InChI=1S/C13H18O3/c1-7(2)9-5-10(8(3)4)12(14)11(6-9)13(15)16/h5-8,14H,1-4H3,(H,15,16)
描述信息
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Xiao Guo, Zhongkai Wang, Xu Geng, Yanan Shang, Yunlong Zhao, Maoheng Zu, Hao Xu. The change in the liver volume after direct intrahepatic portocaval shunt in patients with Budd-Chiari syndrome with diffuse hepatic vein occlusion.
Abdominal radiology (New York).
2023 01; 48(1):291-296. doi:
10.1007/s00261-022-03683-2. [PMID: 36201055] - Takanori Matsui, Yuri Nishino, Sayaka Maeda, Masayoshi Takeuchi, Sho-ichi Yamagishi. Irbesartan inhibits advanced glycation end product (AGE)-induced up-regulation of vascular cell adhesion molecule-1 (VCAM-1) mRNA levels in glomerular endothelial cells.
Microvascular research.
2011 May; 81(3):269-73. doi:
10.1016/j.mvr.2011.01.001. [PMID: 21236267] - Eugene O Apostolov, Izoumroud Soultanova, Alena Savenka, Osman O Bagandov, Xiaoyan Yin, Anna G Stewart, Richard B Walker, Alexei G Basnakian. Deoxyribonuclease I is essential for DNA fragmentation induced by gamma radiation in mice.
Radiation research.
2009 Oct; 172(4):481-92. doi:
10.1667/rr1647.1. [PMID: 19772469] - V Brumas, H Miche, M Fiallo. Copper(II) interaction with 3,5-diisopropylsalicylic acid (Dips): new insights on its role as a potential *OH inactivating ligand.
Journal of inorganic biochemistry.
2007 Apr; 101(4):565-77. doi:
10.1016/j.jinorgbio.2006.11.017. [PMID: 17234268] - Clifton Blincoe, Mani Chidambaram, Hamid Salari, Kyle B Bond, Doris T Evans, Rhonda A Gray-Kaufman, Hal Brent Griffey, Sandra Gilbreth Tranby, Buffy Garner-Johnson, Tina Lee, John R J Sorenson. Pharmacokinetic distribution of 67Cu(II)2[3,5-diisopropyl(carboxy-14C)salicylate]4 among murine tissues.
Current medicinal chemistry.
2004 Nov; 11(22):3007-15. doi:
10.2174/0929867043363992. [PMID: 15544486] - Margarita H Malakyan, Sergey A Bajinyan, Armenuhi K Abrahamyan, Zhasmena H Petrosyan, Nektar K Harutyunyan, Vardush A Badiryan, John R J Sorenson. Pharmacological and haematological results of rat skin burn injury treatment with Cu(II)2(3,5-diisopropylsalicylate)4.
Inflammopharmacology.
2004; 12(4):321-51. doi:
10.1163/1568560043696209. [PMID: 15901413] - I H El-Sayed, S M El-Masry. Protection against cisplatin-induced nephrotoxicity by Cu(II)2(3,5-diisopropylsalicylate)4.
Redox report : communications in free radical research.
2003; 8(1):47-50. doi:
10.1179/135100003125001242. [PMID: 12631444] - M Roch-Arveiller, V Revelant, D Pham Huy, L Maman, J Fontagne, J R Sorenson, J P Giroud. Effects of some non-steroidal anti-inflammatory drug copper complexes on polymorphonuclear leukocyte oxidative metabolism.
Agents and actions.
1990 Aug; 31(1-2):65-71. doi:
10.1007/bf02003223. [PMID: 2178320] - M K Samson, R L Stephens, S Rivkin, M Opipari, T Maloney, C W Groppe, R Fisher. Vinblastine, bleomycin, and cis-dichlorodiammineplatinum(II) in disseminated testicular cancer: preliminary report of a Southwest Oncology Group Study.
Cancer treatment reports.
1979 Sep; 63(9-10):1663-7. doi:
. [PMID: 91435]
