2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 2-phenylethyl ester (BioDeep_00000174043)
human metabolite blood metabolite
代谢物信息卡片
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 2-phenylethyl ester
化学式: C17H16O4 (284.1048536)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: OC1=CC=C(C=CC(=O)OCCC2=CC=CC=C2)C=C1O
InChI: InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 4307 - Euonymus alatus: 10.1096/FJ.04-2126COM
- 9606 - Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Anongporn Kobroob, Nipon Chattipakorn, Orawan Wongmekiat. Caffeic acid phenethyl ester ameliorates cadmium-induced kidney mitochondrial injury.
Chemico-biological interactions.
2012 Oct; 200(1):21-7. doi:
10.1016/j.cbi.2012.08.026. [PMID: 22982771] - Heba H Mansour, Sameh S Tawfik. Early treatment of radiation-induced heart damage in rats by caffeic acid phenethyl ester.
European journal of pharmacology.
2012 Oct; 692(1-3):46-51. doi:
10.1016/j.ejphar.2012.06.037. [PMID: 22771294] - Coral O Omene, Jing Wu, Krystyna Frenkel. Caffeic Acid Phenethyl Ester (CAPE) derived from propolis, a honeybee product, inhibits growth of breast cancer stem cells.
Investigational new drugs.
2012 Aug; 30(4):1279-88. doi:
10.1007/s10637-011-9667-8. [PMID: 21537887] - Mukaddes Eşrefoğlu, Mustafa Iraz, Burhan Ateş, Mehmet Gül. Not only melatonin but also caffeic acid phenethyl ester protects kidneys against aging-related oxidative damage in Sprague Dawley rats.
Ultrastructural pathology.
2012 Aug; 36(4):244-51. doi:
10.3109/01913123.2012.679351. [PMID: 22849526] - Fatma Ben Abdallah, Hamadi Fetoui, Nassira Zribi, Feiza Fakhfakh, Leila Keskes. Protective role of caffeic acid on lambda cyhalothrin-induced changes in sperm characteristics and testicular oxidative damage in rats.
Toxicology and industrial health.
2012 Aug; 28(7):639-47. doi:
10.1177/0748233711420470. [PMID: 22025501] - N C Roso, R R M Correa, Y M M Castiglia, L R Carvalho, L M Scatena, A V G de Souza, C C de Oliveira, P T G Vianna. Caffeic acid phenethyl ester effects in the kidney during ischemia and reperfusion in rats anesthetized with isoflurane.
Transplantation proceedings.
2012 Jun; 44(5):1211-3. doi:
10.1016/j.transproceed.2012.01.137. [PMID: 22663986] - Caiming Tang, O Samuel Sojinu. Simultaneous determination of caffeic acid phenethyl ester and its metabolite caffeic acid in dog plasma using liquid chromatography tandem mass spectrometry.
Talanta.
2012 May; 94(?):232-9. doi:
10.1016/j.talanta.2012.03.029. [PMID: 22608441] - John Yang, Sean M Kerwin, Phillip D Bowman, Salomon Stavchansky. Stability of caffeic acid phenethyl amide (CAPA) in rat plasma.
Biomedical chromatography : BMC.
2012 May; 26(5):594-8. doi:
10.1002/bmc.1702. [PMID: 21915890] - Ghassan Mohammad Sulaiman. Role of caffeic acid phenethyl ester on mitomycin C induced clastogenesis: analysis of chromosome aberrations, micronucleus, mitotic index and adenosine deaminase activity in vivo.
Journal of applied genetics.
2012 May; 53(2):213-9. doi:
10.1007/s13353-012-0089-x. [PMID: 22382517] - Fadime Ozge Aygün, Füsun Zeynep Akçam, Onur Kaya, Betül Mermi Ceyhan, Recep Sütçü. Caffeic acid phenethyl ester modulates gentamicin-induced oxidative nephrotoxicity in kidney of rats.
Biological trace element research.
2012 Feb; 145(2):211-6. doi:
10.1007/s12011-011-9172-0. [PMID: 21870154] - Giuseppina Basini, Laura Baioni, Simona Bussolati, Francesca Grasselli, Carmelo Daquino, Carmela Spatafora, Corrado Tringali. Antiangiogenic properties of an unusual benzo[k,l]xanthene lignan derived from CAPE (caffeic acid phenethyl ester).
Investigational new drugs.
2012 Feb; 30(1):186-90. doi:
10.1007/s10637-010-9550-z. [PMID: 20924642] - Yasar Bozkurt, Mehtap Bozkurt, Gul Turkçu, Ahmet Ali Sancaktutar, Haluk Soylemez, Necmettin Penbegul, Murat Atar, Mehmet Nuri Bodakcı, Namık Kemal Hatipoglu, Hatice Yuksel, Erkan Kıbrıslı, Celal Yavuz. Caffeic acid phenethyl ester protects kidneys against acetylsalicylic acid toxicity in rats.
Renal failure.
2012; 34(9):1150-5. doi:
10.3109/0886022x.2012.717485. [PMID: 22950656] - Hui Chen, Julie-Thu A Tran, Robert E Anderson, Md Nawajes A Mandal. Caffeic acid phenethyl ester protects 661W cells from H2O2-mediated cell death and enhances electroretinography response in dim-reared albino rats.
Molecular vision.
2012; 18(?):1325-38. doi:
. [PMID: 22690111] - Monika Bhadauria. Propolis prevents hepatorenal injury induced by chronic exposure to carbon tetrachloride.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):235358. doi:
10.1155/2012/235358. [PMID: 21837248] - Pavle Randjelovic, Slavimir Veljkovic, Nenad Stojiljkovic, Ljubinka Jankovic-Velickovic, Dusan Sokolovic, Milan Stoiljkovic, Ivan Ilic. Salicylic acid attenuates gentamicin-induced nephrotoxicity in rats.
TheScientificWorldJournal.
2012; 2012(?):390613. doi:
10.1100/2012/390613. [PMID: 22666115] - Andresa Aparecida Berretta, Andresa Piacezzi Nascimento, Paula Carolina Pires Bueno, Mirela Mara de Oliveira Lima Leite Vaz, Juliana Maldonado Marchetti. Propolis standardized extract (EPP-AF®), an innovative chemically and biologically reproducible pharmaceutical compound for treating wounds.
International journal of biological sciences.
2012; 8(4):512-21. doi:
10.7150/ijbs.3641. [PMID: 22457606] - Emin Ozbek. Induction of oxidative stress in kidney.
International journal of nephrology.
2012; 2012(?):465897. doi:
10.1155/2012/465897. [PMID: 22577546] - Pin Gong, Fuxin Chen, Xiaoying Liu, Xing Gong, Jing Wang, Yangmin Ma. Protective effect of caffeic acid phenethyl ester against cadmium-induced renal damage in mice.
The Journal of toxicological sciences.
2012; 37(2):415-25. doi:
10.2131/jts.37.415. [PMID: 22467032] - Yajing Li, Minli Chen, Hongzhuan Xuan, Fuliang Hu. Effects of encapsulated propolis on blood glycemic control, lipid metabolism, and insulin resistance in type 2 diabetes mellitus rats.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):981896. doi:
10.1155/2012/981896. [PMID: 21716678] - Luc H Boudreau, Jacques Maillet, Luc M LeBlanc, Jacques Jean-François, Mohamed Touaibia, Nicolas Flamand, Marc E Surette. Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes.
PloS one.
2012; 7(2):e31833. doi:
10.1371/journal.pone.0031833. [PMID: 22347509] - Hui-Ping Lin, Li-Kuo Kuo, Chih-Pin Chuu. Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells.
Phytotherapy research : PTR.
2012 Jan; 26(1):122-6. doi:
10.1002/ptr.3523. [PMID: 21567511] - Gabriele Multhoff, Jürgen Radons. Radiation, inflammation, and immune responses in cancer.
Frontiers in oncology.
2012; 2(?):58. doi:
10.3389/fonc.2012.00058. [PMID: 22675673] - Marcin Barylski, Jolanta Małyszko, Jacek Rysz, Michał Myśliwiec, Maciej Banach. Lipids, blood pressure, kidney - what was new in 2011?.
Archives of medical science : AMS.
2011 Dec; 7(6):1055-66. doi:
10.5114/aoms.2011.26620. [PMID: 22328891] - Ahmet Tekin, Serdar Türkyılmaz, Tevfik Küçükkartallar, Murat Cakır, Hüseyin Yılmaz, Hasan Esen, Burhan Ateş, Ilhan Ciftci, Adil Kartal. Effects of caffeic acid phenethyl ester (CAPE) on hepatopulmonary syndrome.
Inflammation.
2011 Dec; 34(6):614-9. doi:
10.1007/s10753-010-9270-8. [PMID: 21046212] - Tuğrul Çakır, Erkan Özkan, Ender Dulundu, Ümit Topaloğlu, Ahmet Özer Şehirli, Feriha Ercan, Emre Şener, Göksel Şener. Caffeic acid phenethyl ester (CAPE) prevents methotrexate-induced hepatorenal oxidative injury in rats.
The Journal of pharmacy and pharmacology.
2011 Dec; 63(12):1566-71. doi:
10.1111/j.2042-7158.2011.01359.x. [PMID: 22060287] - Hülya Göçer, Ilhami Gülçin. Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties.
International journal of food sciences and nutrition.
2011 Dec; 62(8):821-5. doi:
10.3109/09637486.2011.585963. [PMID: 21631390] - Tanja Cigut, Tomaž Polak, Lea Gašperlin, Peter Raspor, Polona Jamnik. Antioxidative activity of propolis extract in yeast cells.
Journal of agricultural and food chemistry.
2011 Nov; 59(21):11449-55. doi:
10.1021/jf2022258. [PMID: 21958212] - Orawan Wongmekiat, Sumittra Gomonchareonsiri, Kamthorn Thamprasert. Caffeic acid phenethyl ester protects against oxidative stress-related renal dysfunction in rats treated with cyclosporin A.
Fundamental & clinical pharmacology.
2011 Oct; 25(5):619-26. doi:
10.1111/j.1472-8206.2010.00884.x. [PMID: 21077939] - Mukaddes Eşrefoğlu, Mehmet Gül, Burhan Ateş, Ali Erdoğan. The effects of caffeic acid phenethyl ester and melatonin on age-related vascular remodeling and cardiac damage.
Fundamental & clinical pharmacology.
2011 Oct; 25(5):580-90. doi:
10.1111/j.1472-8206.2010.00876.x. [PMID: 20880386] - Maria Graça Miguel, Maria Dulce Antunes. Is propolis safe as an alternative medicine?.
Journal of pharmacy & bioallied sciences.
2011 Oct; 3(4):479-95. doi:
10.4103/0975-7406.90101. [PMID: 22219581] - Aida Abdelhamid Korish, Maha Mohamed Arafa. Propolis derivatives inhibit the systemic inflammatory response and protect hepatic and neuronal cells in acute septic shock.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases.
2011 Jul; 15(4):332-8. doi:
. [PMID: 21861003] - Marija Bošković, Tomaž Vovk, Blanka Kores Plesničar, Iztok Grabnar. Oxidative stress in schizophrenia.
Current neuropharmacology.
2011 Jun; 9(2):301-12. doi:
10.2174/157015911795596595. [PMID: 22131939] - Chia-Yuan Liu, Hsun-Shuo Chang, Ih-Sheng Chen, Chih-Jen Chen, Ming-Ling Hsu, Shu-Ling Fu, Yu-Jen Chen. Costunolide causes mitotic arrest and enhances radiosensitivity in human hepatocellular carcinoma cells.
Radiation oncology (London, England).
2011 May; 6(?):56. doi:
10.1186/1748-717x-6-56. [PMID: 21624128] - Tarek K Motawi, Hebatallah A Darwish, Azza M Abd El Tawab. Effects of caffeic acid phenethyl ester on endotoxin-induced cardiac stress in rats: a possible mechanism of protection.
Journal of biochemical and molecular toxicology.
2011 Mar; 25(2):84-94. doi:
10.1002/jbt.20362. [PMID: 21472898] - Shashi K Kudugunti, Nikhil M Vad, Ehi Ekogbo, Majid Y Moridani. Efficacy of caffeic acid phenethyl ester (CAPE) in skin B16-F0 melanoma tumor bearing C57BL/6 mice.
Investigational new drugs.
2011 Feb; 29(1):52-62. doi:
10.1007/s10637-009-9334-5. [PMID: 19844662] - Neriman Colakoglu, Ilter Kus, Aysel Kukner, Hidir Pekmez, Enver Ozan, Mustafa Sarsilmaz. Protective effects of CAPE on liver injury induced by CCL₄: an electron microscopy study.
Ultrastructural pathology.
2011 Feb; 35(1):26-30. doi:
10.3109/01913123.2010.527036. [PMID: 21265632] - Elizabeth A Mazzio, Fran Close, Karam F A Soliman. The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.
International journal of molecular sciences.
2011 Jan; 12(1):506-69. doi:
10.3390/ijms12010506. [PMID: 21340000] - Lizhi Xu, Jing Gao, Yucai Wang, Wen Yu, Xiaoning Zhao, Xiaohe Yang, Zengtao Zhong, Zhong-Ming Qian. Myrica rubra Extracts Protect the Liver from CCl(4)-Induced Damage.
Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):518302. doi:
10.1093/ecam/nep196. [PMID: 20019074] - Yeu-Ching Shi, Jiunn-Wang Liao, Tzu-Ming Pan. Antihypertriglyceridemia and anti-inflammatory activities of monascus-fermented dioscorea in streptozotocin-induced diabetic rats.
Experimental diabetes research.
2011; 2011(?):710635. doi:
10.1155/2011/710635. [PMID: 21716679] - M Al-Hariri, T Gamal Eldin, B Abu-Hozaifa, A Elnour. Glycemic control and anti-osteopathic effect of propolis in diabetic rats.
Diabetes, metabolic syndrome and obesity : targets and therapy.
2011; 4(?):377-84. doi:
10.2147/dmso.s24159. [PMID: 22253535] - Zuhal Yildirim, Nil Irem Ucgun, Filiz Yildirim. The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration.
Clinics (Sao Paulo, Brazil).
2011; 66(5):743-6. doi:
10.1590/s1807-59322011000500006. [PMID: 21789374] - Saeed Samarghandian, Jalil Tavakkol Afshari, Saiedeh Davoodi. Honey induces apoptosis in renal cell carcinoma.
Pharmacognosy magazine.
2011 Jan; 7(25):46-52. doi:
10.4103/0973-1296.75901. [PMID: 21472079] - Ali Karadeniz, Nejdet Simsek, Emre Karakus, Serap Yildirim, Adem Kara, Ismail Can, Fikrullah Kisa, Habib Emre, Mehmet Turkeli. Royal jelly modulates oxidative stress and apoptosis in liver and kidneys of rats treated with cisplatin.
Oxidative medicine and cellular longevity.
2011; 2011(?):981793. doi:
10.1155/2011/981793. [PMID: 21904651] - Wei Zhu, Minli Chen, Qiyang Shou, Yinghua Li, Fuliang Hu. Biological activities of chinese propolis and brazilian propolis on streptozotocin-induced type 1 diabetes mellitus in rats.
Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):468529. doi:
10.1093/ecam/neq025. [PMID: 21785625] - Sule Ayla, Ismail Seckin, Gamze Tanriverdi, Mujgan Cengiz, Mediha Eser, B C Soner, Gulperi Oktem. Doxorubicin induced nephrotoxicity: protective effect of nicotinamide.
International journal of cell biology.
2011; 2011(?):390238. doi:
10.1155/2011/390238. [PMID: 21789041] - Ali Said Durmus, Hamit Yildiz, Ihsan Yaman, Halil Simsek. Efficacy of vitamin E and selenium for the prevention of intra-abdominal adhesions in rats: uterine horn models.
Clinics (Sao Paulo, Brazil).
2011; 66(7):1247-51. doi:
10.1590/s1807-59322011000700021. [PMID: 21876982] - Ersin Fadillioglu, Cebrail Gursul, Mustafa Iraz. Effects of caffeic acid phenethyl ester on thioacetamide-induced hepatic encephalopathy in rats.
Progress in neuro-psychopharmacology & biological psychiatry.
2010 Dec; 34(8):1440-5. doi:
10.1016/j.pnpbp.2010.07.034. [PMID: 20708059] - Hamid Tayefi, Amac Kiray, Muge Kiray, Bekir Ugur Ergur, Husnu Alper Bagriyanik, Cetin Pekcetin, Mustafa Fidan, Candan Ozogul. The effects of prenatal and neonatal exposure to electromagnetic fields on infant rat myocardium.
Archives of medical science : AMS.
2010 Dec; 6(6):837-42. doi:
10.5114/aoms.2010.19288. [PMID: 22427754] - Griselda Wilson-Sanchez, Carolina Moreno-Félix, Carlos Velazquez, Maribel Plascencia-Jatomea, Anita Acosta, Lorena Machi-Lara, María-Lourdes Aldana-Madrid, Josafat-Marina Ezquerra-Brauer, Ramón Robles-Zepeda, Armando Burgos-Hernandez. Antimutagenicity and antiproliferative studies of lipidic extracts from white shrimp (Litopenaeus vannamei).
Marine drugs.
2010 Nov; 8(11):2795-809. doi:
10.3390/md8112795. [PMID: 21139845] - Amel Nakbi, Wafa Tayeb, Abir Grissa, Manel Issaoui, Samia Dabbou, Issam Chargui, Meriem Ellouz, Abdelhedi Miled, Mohamed Hammami. Effects of olive oil and its fractions on oxidative stress and the liver's fatty acid composition in 2,4-Dichlorophenoxyacetic acid-treated rats.
Nutrition & metabolism.
2010 Oct; 7(?):80. doi:
10.1186/1743-7075-7-80. [PMID: 21034436] - Gabriella Aviello, Caterina Scalisi, Rosaria Fileccia, Raffaele Capasso, Barbara Romano, Angelo A Izzo, Francesca Borrelli. Inhibitory effect of caffeic acid phenethyl ester, a plant-derived polyphenolic compound, on rat intestinal contractility.
European journal of pharmacology.
2010 Aug; 640(1-3):163-7. doi:
10.1016/j.ejphar.2010.04.040. [PMID: 20451513] - Süleyman Oktar, Mehmet Aydin, Zafer Yönden, Ergül Alçin, Selçuk Ilhan, Ahmet Nacar. Effects of caffeic acid phenethyl ester on isoproterenol-induced myocardial infarction in rats.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology.
2010 Aug; 10(4):298-302. doi:
10.5152/akd.2010.086. [PMID: 20693123] - Mohamed F El-Refaei, Mona M El-Naa. Inhibitory effect of caffeic acid phenethyl ester on mice bearing tumor involving angiostatic and apoptotic activities.
Chemico-biological interactions.
2010 Jul; 186(2):152-6. doi:
10.1016/j.cbi.2010.04.019. [PMID: 20433813] - Mukaddes Eşrefoğlu, Mehmet Gül, Burhan Ateş, Ismet Yilmaz. The ultrastructural and biochemical evidences of the beneficial effects of chronic caffeic acid phenethyl ester and melatonin administration on brain and cerebellum of aged rats.
Fundamental & clinical pharmacology.
2010 Jun; 24(3):305-15. doi:
10.1111/j.1472-8206.2009.00782.x. [PMID: 19817869] - Hidir Pekmez, Murat Ogeturk, Huseyin Ozyurt, Mehmet Fatih Sonmez, Neriman Colakoglu, Ilter Kus. Ameliorative effect of caffeic acid phenethyl ester on histopathological and biochemical changes induced by cigarette smoke in rat kidney.
Toxicology and industrial health.
2010 Apr; 26(3):175-82. doi:
10.1177/0748233710362380. [PMID: 20176779] - Ji Yeon Seo, Soon Sung Lim, Jia Park, Ji-Sun Lim, Hyo Jung Kim, Hui Jung Kang, Jung Han Yoon Park, Jong-Sang Kim. Protection by Chrysanthemum zawadskii extract from liver damage of mice caused by carbon tetrachloride is maybe mediated by modulation of QR activity.
Nutrition research and practice.
2010 Apr; 4(2):93-8. doi:
10.4162/nrp.2010.4.2.93. [PMID: 20461196] - Aida A Korish. Effect of caffeic acid phenethyl ester on the hemostatic alterations associated with toxic-induced acute liver failure.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
2010 Mar; 21(2):158-63. doi:
10.1097/mbc.0b013e32833678be. [PMID: 20087173] - Mehmet Colbay, Seref Yuksel, Ihsan Uslan, Gursel Acarturk, Ozcan Karaman, Orhan Bas, Hakan Mollaoglu, Murat Yagmurca, Oguz Aslan Ozen. Novel approach for the prevention of contrast nephropathy.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2010 Jan; 62(1):81-9. doi:
10.1016/j.etp.2009.02.119. [PMID: 19327972] - Asim Kart, Yilmaz Cigremis, Musa Karaman, Hasan Ozen. Caffeic acid phenethyl ester (CAPE) ameliorates cisplatin-induced hepatotoxicity in rabbit.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2010 Jan; 62(1):45-52. doi:
10.1016/j.etp.2009.02.066. [PMID: 19268559] - Sachiko Juman, Naomi Yasui, Hiroto Okuda, Ai Ueda, Hiroko Negishi, Tomohiro Miki, Katsumi Ikeda. Caffeic acid phenethyl ester inhibits differentiation to adipocytes in 3T3-L1 mouse fibroblasts.
Biological & pharmaceutical bulletin.
2010; 33(9):1484-8. doi:
10.1248/bpb.33.1484. [PMID: 20823561] - M I Khalil, S A Sulaiman. The potential role of honey and its polyphenols in preventing heart diseases: a review.
African journal of traditional, complementary, and alternative medicines : AJTCAM.
2010; 7(4):315-21. doi:
10.4314/ajtcam.v7i4.56693. [PMID: 21731163] - Hiroshi Izuta, Yukimi Narahara, Masamitsu Shimazawa, Satoshi Mishima, Shin-ichi Kondo, Hideaki Hara. 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity of bee products and their constituents determined by ESR.
Biological & pharmaceutical bulletin.
2009 Dec; 32(12):1947-51. doi:
10.1248/bpb.32.1947. [PMID: 19952409] - S Oktar, Z Yönden, M Aydin, S Ilhan, E Alçin, O H Oztürk. Protective effects of caffeic acid phenethyl ester on iron-induced liver damage in rats.
Journal of physiology and biochemistry.
2009 Dec; 65(4):339-44. doi:
10.1007/bf03185928. [PMID: 20358346] - Hiroshi Izuta, Masamitsu Shimazawa, Kazuhiro Tsuruma, Yoko Araki, Satoshi Mishima, Hideaki Hara. Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells.
BMC complementary and alternative medicine.
2009 Nov; 9(?):45. doi:
10.1186/1472-6882-9-45. [PMID: 19917137] - Nisarg R Desai, Kavindra K Kesari, Ashok Agarwal. Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system.
Reproductive biology and endocrinology : RB&E.
2009 Oct; 7(?):114. doi:
10.1186/1477-7827-7-114. [PMID: 19849853] - Sefa Celik, Suat Erdogan, Mehmet Tuzcu. Caffeic acid phenethyl ester (CAPE) exhibits significant potential as an antidiabetic and liver-protective agent in streptozotocin-induced diabetic rats.
Pharmacological research.
2009 Oct; 60(4):270-6. doi:
10.1016/j.phrs.2009.03.017. [PMID: 19717012] - A Kart, Y Cigremis, H Ozen, O Dogan. Caffeic acid phenethyl ester prevents ovary ischemia/reperfusion injury in rabbits.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2009 Aug; 47(8):1980-4. doi:
10.1016/j.fct.2009.05.012. [PMID: 19457442] - Ashwag A Albukhari, Hana M Gashlan, Hesham A El-Beshbishy, Ayman A Nagy, Ashraf B Abdel-Naim. Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2009 Jul; 47(7):1689-95. doi:
10.1016/j.fct.2009.04.021. [PMID: 19394397] - Louis-Philippe Precourt, Ernest Seidman, Edgard Delvin, Devendra Amre, Colette Deslandres, Michel Dominguez, Daniel Sinnett, Emile Levy. Comparative expression analysis reveals differences in the regulation of intestinal paraoxonase family members.
The international journal of biochemistry & cell biology.
2009 Jul; 41(7):1628-37. doi:
10.1016/j.biocel.2009.02.013. [PMID: 19401157] - Xinyu Wang, Jihai Pang, Jacqueline A Maffucci, Devendra S Pade, Robert A Newman, Sean M Kerwin, Phillip D Bowman, Salomon Stavchansky. Pharmacokinetics of caffeic acid phenethyl ester and its catechol-ring fluorinated derivative following intravenous administration to rats.
Biopharmaceutics & drug disposition.
2009 Jul; 30(5):221-8. doi:
10.1002/bdd.657. [PMID: 19544289] - Yurdal Serarslan, Ramazan Bal, Muhammed Enes Altuğ, Tünay Kontaş, Ismet Murat Melek. Caffeic acid phenethyl ester decreases the level of S-100B protein after middle cerebral artery [correction for after] occlusion in rabbits.
Pakistan journal of pharmaceutical sciences.
2009 Jul; 22(3):313-6. doi:
NULL. [PMID: 19553181] - A Koyu, F Ozguner, Hr Yilmaz, E Uz, G Cesur, N Ozcelik. The protective effect of caffeic acid phenethyl ester (CAPE) on oxidative stress in rat liver exposed to the 900 MHz electromagnetic field.
Toxicology and industrial health.
2009 Jul; 25(6):429-34. doi:
10.1177/0748233709106821. [PMID: 19671636] - Joo Hyun Nam, Dong Hoon Shin, Haifeng Zheng, Jae Seung Kang, Woo Kyung Kim, Sung Joon Kim. Inhibition of store-operated Ca2+ entry channels and K+ channels by caffeic acid phenethylester in T lymphocytes.
European journal of pharmacology.
2009 Jun; 612(1-3):153-60. doi:
10.1016/j.ejphar.2009.04.004. [PMID: 19371740] - Alireza Javadzadeh, Amir Ghorbanihaghjo, Somayeh Bonyadi, Mohammad Reza Rashidi, Mehran Mesgari, Nadereh Rashtchizadeh, Hassan Argani. Preventive effect of onion juice on selenite-induced experimental cataract.
Indian journal of ophthalmology.
2009 May; 57(3):185-9. doi:
10.4103/0301-4738.49391. [PMID: 19384011] - Yuksel Yildiz, Mukadder Serter, Rauf Onur Ek, Kemal Ergin, Serpil Cecen, Ece Mine Demir, Cigdem Yenisey. Protective effects of caffeic acid phenethyl ester on intestinal ischemia-reperfusion injury.
Digestive diseases and sciences.
2009 Apr; 54(4):738-44. doi:
10.1007/s10620-008-0405-9. [PMID: 18683050] - Kazuyuki Ohara, Asako Uchida, Reiko Nagasaka, Hideki Ushio, Toshiaki Ohshima. The effects of hydroxycinnamic acid derivatives on adiponectin secretion.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2009 Mar; 16(2-3):130-7. doi:
10.1016/j.phymed.2008.09.012. [PMID: 19013780] - Ahmet Gökçe, Süleyman Oktar, Zafer Yönden, Mehmet Aydin, Selçuk Ilhan, Orhan Veli Ozkan, Mürsel Davarci, Fatih Rüştü Yalçinkaya. Protective effect of caffeic acid phenethyl ester on cyclosporine A-induced nephrotoxicity in rats.
Renal failure.
2009; 31(9):843-7. doi:
10.3109/08860220903137517. [PMID: 19925294] - Jung Ok Ban, Ju Hoon Oh, Tae Myoung Kim, Dae Joong Kim, Heon-Sang Jeong, Sang Bae Han, Jin Tae Hong. Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfur compound isolated from garlic via inhibition of NF-kappaB.
Arthritis research & therapy.
2009; 11(5):R145. doi:
10.1186/ar2819. [PMID: 19788760] - Milena Saavedra-Lopes, Fernando S Ramalho, Leandra N Z Ramalho, Alessandra Andrade-Silva, Ana L C Martinelli, Alceu A Jordão, Orlando Castro-e-Silva, Sérgio Zucoloto. The protective effect of CAPE on hepatic ischemia/reperfusion injury in rats.
The Journal of surgical research.
2008 Dec; 150(2):271-7. doi:
10.1016/j.jss.2008.01.039. [PMID: 18621400] - Guy Bertrand Sabas Nya Njomen, René Kamgang, Jean Louis Essame Oyono, Njifutie Njikam. Antioxidant potential of the methanol-methylene chloride extract of Terminalia glaucescens leaves on mice liver in streptozotocin-induced stress.
Indian journal of pharmacology.
2008 Nov; 40(6):266-70. doi:
10.4103/0253-7613.45153. [PMID: 21279183] - Xinyu Wang, Salomon Stavchansky, Baiteng Zhao, James A Bynum, Sean M Kerwin, Phillip D Bowman. Cytoprotection of human endothelial cells from menadione cytotoxicity by caffeic acid phenethyl ester: the role of heme oxygenase-1.
European journal of pharmacology.
2008 Sep; 591(1-3):28-35. doi:
10.1016/j.ejphar.2008.06.017. [PMID: 18573251] - Preetha Anand, Ajaikumar B Kunnumakkara, Ajaikumar B Kunnumakara, Chitra Sundaram, Kuzhuvelil B Harikumar, Sheeja T Tharakan, Oiki S Lai, Bokyung Sung, Bharat B Aggarwal. Cancer is a preventable disease that requires major lifestyle changes.
Pharmaceutical research.
2008 Sep; 25(9):2097-116. doi:
10.1007/s11095-008-9661-9. [PMID: 18626751] - Ahmet Tekin, Tevfik Küçükkartallar, Serdar Türkyilmaz, Ayhan Dinckan, Hasan Esen, Burhan Ateş, Hüseyin Yilmaz, Adil Kartal. Effects of caffeic acid phenethyl ester (CAPE) on sepsis in rats.
Inflammation.
2008 Aug; 31(4):273-80. doi:
10.1007/s10753-008-9075-1. [PMID: 18607706] - Kyung Jin Lee, Jae Ho Choi, Yong Pil Hwang, Young Chul Chung, Hye Gwang Jeong. Protective effect of caffeic acid phenethyl ester on tert-butyl hydroperoxide-induced oxidative hepatotoxicity and DNA damage.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Jul; 46(7):2445-50. doi:
10.1016/j.fct.2008.03.032. [PMID: 18485557] - A Armagan, E Uzar, E Uz, H R Yilmaz, S Kutluhan, H R Koyuncuoglu, S Soyupek, H Cam, T A Serel. Caffeic acid phenethyl ester modulates methotrexate-induced oxidative stress in testes of rat.
Human & experimental toxicology.
2008 Jul; 27(7):547-52. doi:
10.1177/0960327108092293. [PMID: 18829730] - Kyung Jin Lee, Jae Ho Choi, Tilak Khanal, Yong Pil Hwang, Young Chul Chung, Hye Gwang Jeong. Protective effect of caffeic acid phenethyl ester against carbon tetrachloride-induced hepatotoxicity in mice.
Toxicology.
2008 Jun; 248(1):18-24. doi:
10.1016/j.tox.2008.03.009. [PMID: 18436364] - Xinyu Wang, Jihai Pang, Robert A Newman, Sean M Kerwin, Phillip D Bowman, Salomon Stavchansky. Quantitative determination of fluorinated caffeic acid phenethyl ester derivative from rat blood plasma by liquid chromatography-electrospray ionization tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2008 May; 867(1):138-43. doi:
10.1016/j.jchromb.2008.02.025. [PMID: 18358795] - Ting Wang, Lixiang Chen, Weimin Wu, Yuan Long, Rui Wang. Potential cytoprotection: antioxidant defence by caffeic acid phenethyl ester against free radical-induced damage of lipids, DNA, and proteins.
Canadian journal of physiology and pharmacology.
2008 May; 86(5):279-87. doi:
10.1139/y08-029. [PMID: 18432289] - Sefa Celik, Suat Erdogan. Caffeic acid phenethyl ester (CAPE) protects brain against oxidative stress and inflammation induced by diabetes in rats.
Molecular and cellular biochemistry.
2008 May; 312(1-2):39-46. doi:
10.1007/s11010-008-9719-3. [PMID: 18265948] - Muhammed Enes Altuğ, Yurdal Serarslan, Ramazan Bal, Tünay Kontaş, Fatih Ekici, Ismet M Melek, Hüseyin Aslan, Taşkin Duman. Caffeic acid phenethyl ester protects rabbit brains against permanent focal ischemia by antioxidant action: a biochemical and planimetric study.
Brain research.
2008 Mar; 1201(?):135-42. doi:
10.1016/j.brainres.2008.01.053. [PMID: 18308295] - Won-Kyo Jung, Da-Young Lee, Yung Hyun Choi, Sung Su Yea, Inhak Choi, Sae-Gwang Park, Su-Kil Seo, Soo-Woong Lee, Chang-Min Lee, Se-kwon Kim, You-Jin Jeon, Il-Whan Choi. Caffeic acid phenethyl ester attenuates allergic airway inflammation and hyperresponsiveness in murine model of ovalbumin-induced asthma.
Life sciences.
2008 Mar; 82(13-14):797-805. doi:
10.1016/j.lfs.2008.01.014. [PMID: 18299139] - Serdar Turkyilmaz, Etem Alhan, Cengiz Ercin, Birgul Kural Vanizor, Nese Kaklikkaya, Burhan Ates, Selim Erdogan, Serdar Topaloglu. Effects of caffeic acid phenethyl ester on pancreatitis in rats.
The Journal of surgical research.
2008 Mar; 145(1):19-24. doi:
10.1016/j.jss.2007.04.019. [PMID: 18028950] - Sae-Gwang Park, Da-Young Lee, Su-Kil Seo, Soo-Woong Lee, Se-Kwon Kim, Won-Kyo Jung, Mi-Seon Kang, Yung Hyun Choi, Sung Su Yea, Inhak Choi, Il-Whan Choi. Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis.
Toxicology and applied pharmacology.
2008 Jan; 226(1):22-9. doi:
10.1016/j.taap.2007.08.003. [PMID: 17884125] - Won-Kyo Jung, Inhak Choi, Da-Young Lee, Sung Su Yea, Yung Hyun Choi, Moon-Moo Kim, Sae-Gwang Park, Su-Kil Seo, Soo-Woong Lee, Chang-Min Lee, Yeong-Min Park, Il-Whan Choi. Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways.
The international journal of biochemistry & cell biology.
2008; 40(11):2572-82. doi:
10.1016/j.biocel.2008.05.005. [PMID: 18571461] - Oscar A Bizzozero, Savanna Reyes, Jennifer Ziegler, Suzanne Smerjac. Lipid peroxidation scavengers prevent the carbonylation of cytoskeletal brain proteins induced by glutathione depletion.
Neurochemical research.
2007 Dec; 32(12):2114-22. doi:
10.1007/s11064-007-9377-y. [PMID: 17551832] - Victor Paromov, Zacharias Suntres, Milton Smith, William L Stone. Sulfur mustard toxicity following dermal exposure: role of oxidative stress, and antioxidant therapy.
Journal of burns and wounds.
2007 Oct; 7(?):e7. doi:
". [PMID: 18091984] - Mehmet Guney, Baha Oral, Nermin Karahan, Tamer Mungan. Protective effect of caffeic acid phenethyl ester (CAPE) on fluoride-induced oxidative stress and apoptosis in rat endometrium.
Environmental toxicology and pharmacology.
2007 Sep; 24(2):86-91. doi:
10.1016/j.etap.2007.01.005. [PMID: 21783794] - Huseyin Ozyurt, Birsen Ozyurt, Kenan Koca, Salih Ozgocmen. Caffeic acid phenethyl ester (CAPE) protects rat skeletal muscle against ischemia-reperfusion-induced oxidative stress.
Vascular pharmacology.
2007 Aug; 47(2-3):108-12. doi:
10.1016/j.vph.2007.04.008. [PMID: 17543587] - Mushfiquddin Khan, Chinnasamy Elango, Mubeen A Ansari, Inderjit Singh, Avtar K Singh. Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia.
Journal of neurochemistry.
2007 Jul; 102(2):365-77. doi:
10.1111/j.1471-4159.2007.04526.x. [PMID: 17437550]