3-Propoxy-1H-pyrazole-4,5-diol (BioDeep_00000173996)
human metabolite blood metabolite
代谢物信息卡片
化学式: C6H10N2O3 (158.0691)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 81.25%
分子结构信息
SMILES: CCCOC1=C(C(=O)NN1)O
InChI: InChI=1S/C6H10N2O3/c1-2-3-11-6-4(9)5(10)7-8-6/h9H,2-3H2,1H3,(H2,7,8,10)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Estatira Sepehr, Marketa Lebl-Rinnova, Meagan K Mann, Samantha L Pisani, Mona I Churchwell, Donna L Korol, John A Katzenellenbogen, Daniel R Doerge. Pharmacokinetics of the estrogen receptor subtype-selective ligands, PPT and DPN: quantification using UPLC-ES/MS/MS.
Journal of pharmaceutical and biomedical analysis.
2012 Dec; 71(?):119-26. doi:
10.1016/j.jpba.2012.08.022. [PMID: 22981216] - J Liu, P H Bisschop, L Eggels, E Foppen, E Fliers, J N Zhou, A Kalsbeek. Intrahypothalamic estradiol modulates hypothalamus-pituitary-adrenal-axis activity in female rats.
Endocrinology.
2012 Jul; 153(7):3337-44. doi:
10.1210/en.2011-2176. [PMID: 22562172] - Michael J Chisamore, Kwok-Lam Karen Hong, Chun Cheng, Stephen E Alves, Susan P Rohrer, Hilary A Wilkinson. Identification and characterization of lipopolysaccharide binding protein (LBP) as an estrogen receptor α specific serum biomarker.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2012 Mar; 17(2):172-9. doi:
10.3109/1354750x.2012.654406. [PMID: 22299632] - L K Davis, Y Katsu, T Iguchi, D T Lerner, T Hirano, E G Grau. Transcriptional activity and biological effects of mammalian estrogen receptor ligands on three hepatic estrogen receptors in Mozambique tilapia.
The Journal of steroid biochemistry and molecular biology.
2010 Oct; 122(4):272-8. doi:
10.1016/j.jsbmb.2010.05.009. [PMID: 20553864] - Raghvendra K Dubey, Edwin K Jackson, Delbert G Gillespie, Lefteris C Zacharia, Bruno Imthurn, Marinella Rosselli. Resveratrol, a red wine constituent, blocks the antimitogenic effects of estradiol on human female coronary artery smooth muscle cells.
The Journal of clinical endocrinology and metabolism.
2010 Sep; 95(9):E9-17. doi:
10.1210/jc.2010-0460. [PMID: 20534756] - Cecilia Engdahl, Caroline Jochems, Sara H Windahl, Anna E Börjesson, Claes Ohlsson, Hans Carlsten, Marie K Lagerquist. Amelioration of collagen-induced arthritis and immune-associated bone loss through signaling via estrogen receptor alpha, and not estrogen receptor beta or G protein-coupled receptor 30.
Arthritis and rheumatism.
2010 Feb; 62(2):524-33. doi:
10.1002/art.25055. [PMID: 20112355] - Heather B Patisaul, Katherine T Burke, Ruth E Hinkle, Heather B Adewale, Damian Shea. Systemic administration of diarylpropionitrile (DPN) or phytoestrogens does not affect anxiety-related behaviors in gonadally intact male rats.
Hormones and behavior.
2009 Feb; 55(2):319-28. doi:
10.1016/j.yhbeh.2008.11.004. [PMID: 19071129] - Ya-Ching Hsieh, Mashkoor A Choudhry, Huang-Ping Yu, Tomoharu Shimizu, Shaolong Yang, Takao Suzuki, Jianguo Chen, Kirby I Bland, Irshad H Chaudry. Inhibition of cardiac PGC-1alpha expression abolishes ERbeta agonist-mediated cardioprotection following trauma-hemorrhage.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2006 Jun; 20(8):1109-17. doi:
10.1096/fj.05-5549com. [PMID: 16770010] - J Alejandro Arreguin-Arevalo, Terry M Nett. A nongenomic action of 17beta-estradiol as the mechanism underlying the acute suppression of secretion of luteinizing hormone.
Biology of reproduction.
2005 Jul; 73(1):115-22. doi:
10.1095/biolreprod.105.040329. [PMID: 15772257]
