1-Pyrrolidineethanol (BioDeep_00000173798)

   

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


N-(2-Hydroxyethyl)-2,5-(14C)-pyrrolidine

化学式: C6H13NO (115.0997088)
中文名称: 1-(2-羟乙基)吡咯烷, 1-吡咯烷乙醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CCN(C1)CCO
InChI: InChI=1S/C6H13NO/c8-6-5-7-3-1-2-4-7/h8H,1-6H2

描述信息

同义名列表

14 个代谢物同义名

N-(2-Hydroxyethyl)-2,5-(14C)-pyrrolidine; N-beta-Hydroxyethylpyrrolidine; 2-(pyrrolidin-1-yl)ethan-1-ol; 1-(2-Hydroxyethyl)pyrrolidine; N-(2-Hydroxyethyl)pyrrolidine; N-b-Hydroxyethylpyrrolidine; N-Β-hydroxyethylpyrrolidine; Epolamine hydrochloride; 1-Pyrrolidineethanol; 2-Pyrrolidinoethanol; Pyrrolidinoethanol; epolamine; HEP; 1-Pyrrolidineethanol



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Christopher A Jones, Fred K Hoehler, Valeria Frangione, Gilbert Ledesma, Paul P Wisman, Clarence Jones. Safety and Efficacy of the FLECTOR (Diclofenac Epolamine) Topical System in Children with Minor Soft Tissue Injuries: A Phase IV Non-randomized Clinical Trial. Clinical drug investigation. 2022 Jan; 42(1):43-51. doi: 10.1007/s40261-021-01101-x. [PMID: 34826122]
  • Mohamed Ahmed El-Nabarawi, Ahmed Hassen Elshafeey, Dina Mohamed Mahmoud, Amani M El Sisi. Fabrication, optimization, and in vitro/in vivo evaluation of diclofenac epolamine flash tablet. Drug delivery and translational research. 2020 10; 10(5):1314-1326. doi: 10.1007/s13346-020-00709-4. [PMID: 32072473]
  • Liliana L Jorge, Caroline C Feres, Vitor Ep Teles. Topical preparations for pain relief: efficacy and patient adherence. Journal of pain research. 2010 Dec; 4(?):11-24. doi: 10.2147/jpr.s9492. [PMID: 21386951]
  • David R Lionberger, Michael J Brennan. Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch. Journal of pain research. 2010 Nov; 3(?):223-33. doi: 10.2147/jpr.s13238. [PMID: 21197326]
  • K D Rainsford, W F Kean, G E Ehrlich. Review of the pharmaceutical properties and clinical effects of the topical NSAID formulation, diclofenac epolamine. Current medical research and opinion. 2008 Oct; 24(10):2967-92. doi: 10.1185/03007990802381364. [PMID: 18814824]
  • C Giachetti, A Assandri, G Mautone, E Tajana, B Palumbo, R Palumbo. Pharmacokinetics and metabolism of N-(2-hydroxyethyl)-2,5-[14C]-pyrrolidine (HEP, Epolamine) in male healthy volunteers. European journal of drug metabolism and pharmacokinetics. 1996 Jul; 21(3):261-8. doi: 10.1007/bf03189724. [PMID: 8980926]