3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionic acid (BioDeep_00000173653)

   

human metabolite blood metabolite


代谢物信息卡片


beta-(4-Hydroxy-3,5-di-tert-butyl)phenylpropionic acid, potassium salt

化学式: C17H26O3 (278.1881846)
中文名称: 3,5-二叔丁基-4-羟基苯基丙酸
谱图信息: 最多检出来源 Homo sapiens(blood) 99.4%

分子结构信息

SMILES: c1(c(c(cc(c1)CCC(=O)O)C(C)(C)C)O)C(C)(C)C
InChI: InChI=1S/C17H26O3/c1-16(2,3)12-9-11(7-8-14(18)19)10-13(15(12)20)17(4,5)6/h9-10,20H,7-8H2,1-6H3,(H,18,19)

描述信息

D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
D020011 - Protective Agents > D000975 - Antioxidants

同义名列表

23 个代谢物同义名

beta-(4-Hydroxy-3,5-di-tert-butyl)phenylpropionic acid, potassium salt; beta-(4-Hydroxy-3,5-di-tert-butylphenyl)propionic acid; beta-(4-Hydroxy-3,5-di-tertbutylphenyl) propionic acid; beta-(4-Hydroxy-3,5-di-tert-butyl)phenylpropionic acid; 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionic acid; 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoic acid; 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionate; 4-Hydroxy-3,5-di-tert-butylphenylpropionic acid; Fenozan, nickel (2+) salt (2:1); Fenozan, monopotassium salt; Fenozan, monolithium salt; Fenozan, monosodium salt; Potassium phenosan; Potassium fenozan; Fenozan acid; Irganox 1310; Fenozan-K; Phenozan; Fenoksan; Phenoxan; Phenosan; Fenoxan; Fenozan



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nishikant Wase, Boqiang Tu, James W Allen, Paul N Black, Concetta C DiRusso. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. Plant physiology. 2017 Aug; 174(4):2146-2165. doi: 10.1104/pp.17.00433. [PMID: 28652262]
  • E M Mil', A A Albantova, E B Burlakova. [Impact of the antioxidant Phenozan and low dose radiation on the level of p53 and BCL-2 proteins of mice different lines]. Radiatsionnaia biologiia, radioecologiia. 2010 Jan; 50(1):58-64. doi: NULL. [PMID: 20297682]
  • G P Zhizhina, T M Zavarykina, E M Mil', E B Burlakova. [The effects of low doses of low-level gamma-radiation and phenozan injection on structural characteristics of mice spleen DNA]. Radiatsionnaia biologiia, radioecologiia. 2007 Jul; 47(4):414-22. doi: NULL. [PMID: 17953428]
  • R Tripathi, C W Jefford, G P Dutta. Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo. Parasitology. 2006 Jul; 133(Pt 1):1-9. doi: 10.1017/s0031182006009905. [PMID: 16764736]
  • E M Mil', O V Myshliakova, E B Burlakova. [P53 under low-intensity inluence of physical and chemical nature (ionizing radiation and antioxidant)]. Biofizika. 2005 Jan; 50(1):75-9. doi: NULL. [PMID: 15759505]
  • E M Molochkina, I B Ozerova. [The influence of pharmacologically active substances of different classes at ultra low doses on lipid peroxidation in brain cell membranes and activity of acetylcholinesterase in vivo and in vitro]. Radiatsionnaia biologiia, radioecologiia. 2003 May; 43(3):294-300. doi: ". [PMID: 12881982]
  • N P Pal'mina, L V Kledova, T V Pankova, V D Gaintseva. [On the 'receptor' mechanism of the effect of biologically active substances in ultra low concentrations]. Radiatsionnaia biologiia, radioecologiia. 2003 May; 43(3):310-4. doi: ". [PMID: 12881985]
  • V F Mikhaĭlov, V K Mazurik, E B Burlakova. [Signal function of the reactive oxygen species in regulatory networks of the cell reaction to damaging effects: contribution of radiosensitivity and genome instability]. Radiatsionnaia biologiia, radioecologiia. 2003 Jan; 43(1):5-18. doi: ". [PMID: 12677653]
  • I L Pogoretskaia, G V Arkhipova, L M Baĭder, E B Burlakova. [Effect of the antioxidant phenozan and neuropeptide adrenocorticotropic hormone on the structure of the liquid crystalline state of the lipid bilayer and thickness of the phosphatidylcholine membrane]. Biofizika. 1999 Sep; 44(5):852-60. doi: ". [PMID: 10624525]
  • W Peters, B L Robinson, J C Rossier, C W Jefford. The chemotherapy of rodent malaria. XLVIII. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 1: Studies leading to the development of novel cis-fused cyclopenteno derivatives. Annals of tropical medicine and parasitology. 1993 Feb; 87(1):1-7. doi: 10.1080/00034983.1993.11812733. [PMID: 8346987]
  • L N Shishkina, Iu P Taran, S V Eliseeva, V G Bulgakov. [The effect of 6-methyluracil on oxidative reactions in model systems of varying degrees of complexity]. Izvestiia Akademii nauk. Seriia biologicheskaia. 1992 May; ?(3):350-7. doi: ". [PMID: 1304850]
  • A A Ivanov, E M Shilov, O P Gladskikh, O V Gabrilevskaia, N V Nikiforova, M A Pal'tsev. [Immunohistochemical characteristics of serum nephrotoxic nephritis in rats: effect of methylprednisolone and potassium fenozan]. Arkhiv patologii. 1992; 54(1):45-50. doi: NULL. [PMID: 1596184]
  • N V Nikiforova, N V Marchuk, A V Morozov, N V Grishkova, L G Plekhanova. [Urinary enzymes induced in rats by intensive physical loading and the effect of the antioxidant potassium fenozan]. Biulleten' eksperimental'noi biologii i meditsiny. 1989 Jun; 107(6):670-2. doi: NULL. [PMID: 2571366]
  • A P Khokhlov, V N Kirillov. [Effect of the antioxidant fenozan on the physicochemical properties of the kidney cell membranes of rats during nitrosodimethylamine-induced carcinogenesis]. Biulleten' eksperimental'noi biologii i meditsiny. 1988 Nov; 106(11):557-9. doi: NULL. [PMID: 3196854]
  • A P Khokhlov, K N Iarygin. [Specific binding of a synthetic antioxidant from a series of spatially screened phenols, H3-phenozan, with isolated rat enterocytes]. Biulleten' eksperimental'noi biologii i meditsiny. 1988 May; 105(5):545-7. doi: NULL. [PMID: 3382730]
  • A P Khokhlov. [Specific binding of phenol-containing antioxidant with plasma membranes of cells and its inhibition by various biologically active substances]. Doklady Akademii nauk SSSR. 1988; 300(2):494-7. doi: NULL. [PMID: 3168734]
  • V N Kirillov. [Effect of phenozan on nitrosodimethylamine-induced carcinogenesis in rat kidneys]. Eksperimental'naia onkologiia. 1988; 10(5):23-6. doi: NULL. [PMID: 3208684]
  • A P Khokhlov, K N Iarygin. [In vitro effect of synthetic water-soluble antioxidants of the class of screened phenols on the beta-adrenergic system in the cardiocyte plasma membranes of rats]. Biulleten' eksperimental'noi biologii i meditsiny. 1986 Oct; 102(10):415-7. doi: NULL. [PMID: 3021257]
  • I I Mashchakevich. [Blood serum chemiluminescence in a chronic toxicological experiment]. Gigiena i sanitariia. 1986 Apr; ?(4):82-4. doi: NULL. [PMID: 3710225]