Hexamethylquercetagetin (BioDeep_00000017364)

Main id: BioDeep_00000270283

 

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5,6,7-tetramethoxy-

化学式: C21H22O8 (402.1314612)
中文名称: 3,5,6,7,3',4'-六甲氧基黄酮, 3,5,6,7,3,4-六甲氧基黄酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(c(c(c2c(c1)oc(c(c2=O)OC)c1ccc(c(c1)OC)OC)OC)OC)OC
InChI: InChI=1S/C21H22O8/c1-23-12-8-7-11(9-13(12)24-2)18-21(28-6)17(22)16-14(29-18)10-15(25-3)19(26-4)20(16)27-5/h7-10H,1-6H3

描述信息

3-methoxysinensetin, also known as 356734-hexamethoxyflavone, is a member of the class of compounds known as 7-o-methylated flavonoids. 7-o-methylated flavonoids are flavonoids with methoxy groups attached to the C7 atom of the flavonoid backbone. Thus, 3-methoxysinensetin is considered to be a flavonoid lipid molecule. 3-methoxysinensetin is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). 3-methoxysinensetin can be found in grapefruit and sweet orange, which makes 3-methoxysinensetin a potential biomarker for the consumption of these food products.
2-(3,4-dimethoxyphenyl)-3,5,6,7-tetramethoxy-1-benzopyran-4-one is a member of flavonoids and an ether.
Hexamethylquercetagetin is a natural product found in Pulicaria arabica, Chiliadenus montanus, and other organisms with data available.
See also: Tangerine peel (part of); Citrus aurantium fruit rind (part of).
Hexamethylquercetagetin is found in citrus. Hexamethylquercetagetin is isolated from peel of Citrus specie
D004791 - Enzyme Inhibitors

同义名列表

28 个代谢物同义名

4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5,6,7-tetramethoxy-; 2-(3,4-Dimethoxyphenyl)-3,5,6,7-tetramethoxy-4H-1-benzopyran-4-one; 3,5,6,7-Tetrahydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one; 2-(3,4-Dimethoxyphenyl)-3,5,6,7-tetramethoxy-4H-chromen-4-one #; 2-(3,4-Dimethoxyphenyl)-3,5,6,7-tetramethoxy-4H-chromen-4-one; 2-(3,4-dimethoxyphenyl)-3,5,6,7-tetramethoxy-chromen-4-one; 2-(3,4-dimethoxyphenyl)-3,5,6,7-tetramethoxychromen-4-one; 3,5,6,7,3',4'-pentamethoxyflavone; Flavone, 3,3,4,5,6,7-hexamethoxy-; Flavone, 3,5,6,7,3,4-hexamethoxy; 3,3,4,5,6,7-Hexamethoxyflavone; 3,5,6,7,3,4-hexamethoxyflavone; Quercetagetin hexamethyl ether; Quercitagetin hexamethyl ether; Quercetagenin hexamethylether; 3,6,7,3,4-Hexamethoxyflavone; CHXSDKWBSFDZEU-UHFFFAOYSA-N; Oxyayanin B trimethyl ether; Hexa-O-methylquercetagetin; 356734-Hexamethoxyflavone; Hexamethylquercetagetin; 3-Methoxysinensetin; UNII-5MF6VX27BO; quercetagetin; quercetogetin; NCI60_027979; 5MF6VX27BO; Aurantin



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hui Zhang, Jiao Wang, Xinyu Sun, Yalan Zhang, Mengna Dong, Xin Wang, Lihua Li, Li Wang. Fabrication and Characterization of Quercetagetin-Loaded Nanoparticles Based on Shellac and Quaternized Chitosan: Improvement of Encapsulation Efficiency and Acid and Storage Stabilities. Journal of agricultural and food chemistry. 2021 Dec; 69(51):15670-15680. doi: 10.1021/acs.jafc.1c01830. [PMID: 34923817]
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  • Eun Suk Son, Jeong-Woong Park, Se-Hee Kim, Hye Ran Park, Woorijarang Han, O Chul Kwon, Jae Young Nam, Sung Hwan Jeong, Chang Soo Lee. Anti‑inflammatory activity of 3,5,6,7,3',4'‑hexamethoxyflavone via repression of the NF‑κB and MAPK signaling pathways in LPS‑stimulated RAW264.7 cells. Molecular medicine reports. 2020 09; 22(3):1985-1993. doi: 10.3892/mmr.2020.11252. [PMID: 32705181]
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  • Shuai Chen, Yahong Han, Yingqi Wang, Xi Yang, Cuixia Sun, Like Mao, Yanxiang Gao. Zein-hyaluronic acid binary complex as a delivery vehicle of quercetagetin: Fabrication, structural characterization, physicochemical stability and in vitro release property. Food chemistry. 2019 Mar; 276(?):322-332. doi: 10.1016/j.foodchem.2018.10.034. [PMID: 30409601]
  • Shuai Chen, Cuixia Sun, Yingqi Wang, Yahong Han, Lei Dai, Arzigül Abliz, Yanxiang Gao. Quercetagetin-Loaded Composite Nanoparticles Based on Zein and Hyaluronic Acid: Formation, Characterization, and Physicochemical Stability. Journal of agricultural and food chemistry. 2018 Jul; 66(28):7441-7450. doi: 10.1021/acs.jafc.8b01046. [PMID: 29897751]
  • Like Mao, Weiyou Wang, Kedong Tai, Fang Yuan, Yanxiang Gao. Development of a soy protein isolate-carrageenan-quercetagetin non-covalent complex for the stabilization of β-carotene emulsions. Food & function. 2017 Dec; 8(12):4356-4363. doi: 10.1039/c7fo01238a. [PMID: 29067377]
  • Cuixia Sun, Yang Wei, Ruirui Li, Lei Dai, Yanxiang Gao. Quercetagetin-Loaded Zein-Propylene Glycol Alginate Ternary Composite Particles Induced by Calcium Ions: Structure Characterization and Formation Mechanism. Journal of agricultural and food chemistry. 2017 May; 65(19):3934-3945. doi: 10.1021/acs.jafc.7b00921. [PMID: 28460525]
  • Cuixia Sun, Lei Dai, Yanxiang Gao. Binary Complex Based on Zein and Propylene Glycol Alginate for Delivery of Quercetagetin. Biomacromolecules. 2016 12; 17(12):3973-3985. doi: 10.1021/acs.biomac.6b01362. [PMID: 27936716]
  • Yearam Jung, Soon Young Shin, Yeonjoong Yong, Hyeryoung Jung, Seunghyun Ahn, Young Han Lee, Yoongho Lim. Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships. Chemical biology & drug design. 2015 May; 85(5):574-85. doi: 10.1111/cbdd.12445. [PMID: 25298094]
  • Run-Tian Ma, Yan-Ping Shi. Magnetic molecularly imprinted polymer for the selective extraction of quercetagetin from Calendula officinalis extract. Talanta. 2015 Mar; 134(?):650-656. doi: 10.1016/j.talanta.2014.12.003. [PMID: 25618718]
  • Honggao Xu, Xuan Liu, Qiuli Yan, Fang Yuan, Yanxiang Gao. A novel copigment of quercetagetin for stabilization of grape skin anthocyanins. Food chemistry. 2015 Jan; 166(?):50-55. doi: 10.1016/j.foodchem.2014.05.125. [PMID: 25053027]
  • Abdelhakim Ahmed-Belkacem, Jean-François Guichou, Rozenn Brillet, Nazim Ahnou, Eva Hernandez, Coralie Pallier, Jean-Michel Pawlotsky. Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention. Nucleic acids research. 2014 Aug; 42(14):9399-409. doi: 10.1093/nar/gku632. [PMID: 25053847]
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