2,3-Diphenylbenzofuran (BioDeep_00000173525)
human metabolite blood metabolite
代谢物信息卡片
2,3-diphenyl-1-benzofuran
化学式: C20H14O (270.1044594)
中文名称:
谱图信息:
最多检出来源 Bos taurus(endogenous) 3.85%
分子结构信息
SMILES: C1=CC=C(C=C1)C2=C(OC3=CC=CC=C32)C4=CC=CC=C4
InChI: InChI=1S/C20H14O/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)21-20(19)16-11-5-2-6-12-16/h1-14H
描述信息
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 253613
- HMDB: HMDB0245414
- ChEMBL: CHEMBL4581433
- MeSH: Benzofurans
- chemspider: 222278
- CAS: 13054-95-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Romain Magny, Bruno Mégarbane, Lucie Chevillard, Emmanuel Roulland, Benoit Bardèche-Trystram, Véronique Dumestre-Toulet, Laurence Labat, Pascal Houzé. A combined toxicokinetic and metabolic approach to investigate deschloro-N-ethylketamine exposure in a multidrug user.
Journal of pharmaceutical and biomedical analysis.
2024 Jun; 243(?):116086. doi:
10.1016/j.jpba.2024.116086. [PMID: 38518457] - Toshio Morikawa, Naoki Inoue, Saya Yamamoto, Miyuki Shiotani, Yoshiaki Manse, Kiyofumi Ninomiya. Alkylphthalides with intracellular triglyceride metabolism-promoting activity from the rhizomes of Cnidium officinale Makino.
Journal of natural medicines.
2024 Jun; 78(3):709-721. doi:
10.1007/s11418-024-01799-x. [PMID: 38575838] - Rizki Fitriani, Nizar Happyana, Euis Holisotan Hakim. Morushalunin D, a tri-O-bridged Diels-Alder type adduct from Morus alba var. shalun root cultures and the related precursors.
Journal of Asian natural products research.
2024 Jun; 26(6):756-764. doi:
10.1080/10286020.2024.2314193. [PMID: 38379372] - Guilian Zhang, Yuee Sun, Najeeb Ullah, Deepak Kasote, Longyi Zhu, Hui Liu, Ling Xu. Changes in secondary metabolites contents and stress responses in Salvia miltiorrhiza via ScWRKY35 overexpression: Insights from a wild relative Salvia castanea.
Plant physiology and biochemistry : PPB.
2024 Jun; 211(?):108671. doi:
10.1016/j.plaphy.2024.108671. [PMID: 38703500] - Yu-Zhu Tan, Hong-Ling Yan, Yun-Yun Liu, Yong-Ming Yan, Li Wang, Ji-Xu Qiao, Jing Wu, Yin Tian, Cheng Peng. Structurally diverse phthalides from fibrous roots of Ligusticum chuanxiong Hort. and their biological activities.
Fitoterapia.
2024 Jun; 175(?):105882. doi:
10.1016/j.fitote.2024.105882. [PMID: 38452906] - Qianqian Yin, Gang Chen, Danyang Mu, Yuxin Yang, Jinle Hao, Bin Lin, Di Zhou, Yue Hou, Ning Li. Natural anti-neuroinflammatory inhibitors in vitro and in vivo from Aglaia odorata.
Bioorganic chemistry.
2024 Jun; 147(?):107335. doi:
10.1016/j.bioorg.2024.107335. [PMID: 38583250] - Jianzhuan Li, Qiu Liu, Sha Li, Lu Zeng, Jiahui Yao, Hongde Li, Zhongjie Shen, Funeng Lu, Zengxue Wu, Baoan Song, Runjiang Song. Design, Synthesis, Antibacterial Activity, and Mechanisms of Novel Benzofuran Derivatives Containing Disulfide Moieties.
Journal of agricultural and food chemistry.
2024 May; 72(18):10195-10205. doi:
10.1021/acs.jafc.3c08392. [PMID: 38662962] - Lu-Rong Yu, Xian-Zhong Han, Ying-Zi Tang, Dan Liu, Xian-Qin Luo, Xue-Wen Qiu, Jie Feng, Wen-Xiao Yuan, Jia-Yu Ding. Activation of the MEK/ERK Pathway Mediates the Inhibitory Effects of Silvestrol on Nasopharyngeal Carcinoma Cells via RAP1A, HK2, and GADD45A.
Frontiers in bioscience (Landmark edition).
2024 Apr; 29(4):160. doi:
10.31083/j.fbl2904160. [PMID: 38682208] - Xin Wang, Yufeng Jin, Can Di, Yupeng Zeng, Yuqing Zhou, Yu Chen, Zhijun Pan, Zhongxia Li, Wenhua Ling. Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice.
Nutrients.
2024 Apr; 16(8):. doi:
10.3390/nu16081169. [PMID: 38674860] - Rei Funahashi, Fumiaki Matsuura, Masayuki Ninomiya, Sayo Okabe, Shigeo Takashima, Kaori Tanaka, Atsuyoshi Nishina, Mamoru Koketsu. Hybrid pharmacophore design and synthesis of donepezil-inspired aurone derivative salts as multifunctional acetylcholinesterase inhibitors.
Bioorganic chemistry.
2024 Apr; 145(?):107229. doi:
10.1016/j.bioorg.2024.107229. [PMID: 38401360] - Wei Ge, Weikang Ming, Zhenkun Li, Yunyan Tang, Ya-Nan Li, Jue Yang, Xiaojiang Hao, Chunmao Yuan. Design and Synthesis of Cytotoxic Water-Soluble Rocaglaol Derivatives against HEL Cells by Inhibiting Fli-1.
Journal of natural products.
2024 02; 87(2):276-285. doi:
10.1021/acs.jnatprod.3c00948. [PMID: 38253024] - Ying Zhang, Wenjuan Zhai, Minqi Fan, Jinjun Wu, Caiyan Wang. Salvianolic Acid B Significantly Suppresses the Migration of Melanoma Cells via Direct Interaction with β-Actin.
Molecules (Basel, Switzerland).
2024 Feb; 29(4):. doi:
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Science advances.
2024 Feb; 10(6):eadj6547. doi:
10.1126/sciadv.adj6547. [PMID: 38324681] - Guangjun Yu, Yichun Shi, Shiqin Cong, Chengxun Wu, Jing Liu, Yanghui Zhang, Hongyan Liu, Xiuxiu Liu, Haixing Deng, Zhenghuai Tan, Yong Deng. Synthesis and evaluation of butylphthalide-scutellarein hybrids as multifunctional agents for the treatment of Alzheimer's disease.
European journal of medicinal chemistry.
2024 Feb; 265(?):116099. doi:
10.1016/j.ejmech.2023.116099. [PMID: 38160618] - Yijie Li, Ranyun Chen, Jianzhi Wu, Xiaoyong Xue, Tiegang Liu, Guiying Peng, Ruiyu Wu, Lei Wang, Kexin Jia, Yajie Cai, Xiaojiaoyang Li. Salvianolic acid B protects against pulmonary fibrosis by attenuating stimulating protein 1-mediated macrophage and alveolar type 2 cell senescence.
Phytotherapy research : PTR.
2024 Feb; 38(2):620-635. doi:
10.1002/ptr.8070. [PMID: 37953063] - Yadong Fu, Xiaoxi Zhou, Lin Wang, Weiguo Fan, Siqi Gao, Danyan Zhang, Zhiyang Ling, Yaguang Zhang, Liyan Ma, Fang Bai, Jiamei Chen, Bing Sun, Ping Liu. Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis.
Redox biology.
2024 Feb; 69(?):103029. doi:
10.1016/j.redox.2024.103029. [PMID: 38184998] - Rong-Rong Du, Ji-Chao Zhou, Wen-Jie Qin, Kai-Zhou Lu, Xiu-Mei Duan, Ya-Nan Yang, Xiang Yuan, Kun Li, Xiao-Wei Zhang, Pei-Cheng Zhang. Fourteen new 2-benzylbenzofuran glycosides with cardioprotective activity from Heterosmilax yunnanensis.
Bioorganic chemistry.
2024 Feb; 143(?):107079. doi:
10.1016/j.bioorg.2023.107079. [PMID: 38185011] - Qin Lihao, Liu Tingting, Zhang Jiawei, Bai Yifei, Tang Zheyu, Li Jingyan, Xue Tongqing, Jia Zhongzhi. 3D bioprinting of Salvianolic acid B-sodium alginate-gelatin skin scaffolds promotes diabetic wound repair via antioxidant, anti-inflammatory, and proangiogenic effects.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2024 Feb; 171(?):116168. doi:
10.1016/j.biopha.2024.116168. [PMID: 38232662] - Ewelina Piątczak, Joanna Kolniak-Ostek, Weronika Gonciarz, Paweł Lisiecki, Urszula Kalinowska-Lis, Magdalena Szemraj, Magdalena Chmiela, Sylwia Zielińska. The Effect of Salvia tomentosa Miller Extracts, Rich in Rosmarinic, Salvianolic and Lithospermic Acids, on Bacteria Causing Opportunistic Infections.
Molecules (Basel, Switzerland).
2024 Jan; 29(3):. doi:
10.3390/molecules29030590. [PMID: 38338335] - Ai-Cheng Wang, Xiao-Ming Qi, Qing-Fang Li, Yi-Jia Feng, Yuan-Lin Zhang, Hui-Zhi Wei, Jin-Shan Li, Yuan-Biao Qiao, Qing-Shan Li. Methionine redox regulation of actin-interacting proteins primarily governs antioxidative signaling and response to the salvianolic acid B treatment in EA.hy926 cells.
Toxicology and applied pharmacology.
2024 Jan; 483(?):116835. doi:
10.1016/j.taap.2024.116835. [PMID: 38272317] - Xin Hu, Jing Li, Lang Yu, Jemirade Ifejola, Yan Guo, Dandan Zhang, Zahra Khosravi, Kui Zhang, Hongjuan Cui. Screening of anti-melanoma compounds from Morus alba L.: Sanggenon C promotes melanoma cell apoptosis by disrupting intracellular Ca2+ homeostasis.
Journal of ethnopharmacology.
2024 Jan; 324(?):117759. doi:
10.1016/j.jep.2024.117759. [PMID: 38219884] - Xiang Cui, Zehong Huang, Shanshan Deng, Yunxia Zhang, Guoyin Li, Lining Wang, Yanru Deng, Changjing Wu. Benzofuran Derivatives from Cortex Mori Radicis and Their Cholinesterase-Inhibitory Activity.
Molecules (Basel, Switzerland).
2024 Jan; 29(2):. doi:
10.3390/molecules29020315. [PMID: 38257228] - Zhongwei Yao, Minshu Du, Yalu Wang, He Zhu, Luan Shu, Xia You, Jing Wang. Pharmacodynamic study of chitosan in combination with salvianolic acid B in the treatment of CC14 -induced liver fibrosis in mice.
Clinical and experimental pharmacology & physiology.
2024 01; 51(1):17-29. doi:
10.1111/1440-1681.13828. [PMID: 37749921] - Chenyu Feng, Chunhua Hu, Zhaobin Sun, Hao Zhang, Zhaozhao Xu. Experimental study on the effect of Coumarone resin on the performance of SBS-modified asphalt.
PloS one.
2024; 19(4):e0301528. doi:
10.1371/journal.pone.0301528. [PMID: 38635694] - Na Lu, Lei Zhang, Yuqing Tian, Jinghua Yang, Shicun Zheng, Liang Wang, Wei Guo. Biosynthetic pathways and related genes regulation of bioactive ingredients in mulberry leaves.
Plant signaling & behavior.
2023 Dec; 18(1):2287881. doi:
10.1080/15592324.2023.2287881. [PMID: 38014901] - Pinglan Lin, Furong Qiu, Ming Wu, Lin Xu, Di Huang, Chen Wang, Xuejun Yang, Chaoyang Ye. Salvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway.
Pharmaceutical biology.
2023 Dec; 61(1):23-29. doi:
10.1080/13880209.2022.2148169. [PMID: 36524761] - Theerthu Azhamuthu, Suresh Kathiresan, Ilanchitchenni Senkuttuvan, Nihal Ahamed Abulkalam Asath, Pugazhendhi Ravichandran. Usnic acid attenuates 7,12-dimethylbenz[a] anthracene (DMBA) induced oral carcinogenesis through inhibiting oxidative stress, inflammation, and cell proliferation in male golden Syrian hamster model.
Journal of biochemical and molecular toxicology.
2023 Oct; ?(?):e23553. doi:
10.1002/jbt.23553. [PMID: 37840363] - Xiaojing Huang, Tingting Li, Xingyue Jiang, Zhuole Wang, Mingshui Wang, Xia Wu, Ji Li, Junfeng Shi. Co-assembled Supramolecular Hydrogel of Salvianolic Acid B and a Phosphopeptide for Enhanced Wound Healing.
ACS applied materials & interfaces.
2023 Oct; 15(39):45606-45615. doi:
10.1021/acsami.3c09219. [PMID: 37733024] - Koichi Yoshioka, Hoon Kim, Fachuang Lu, Nette De Ridder, Ruben Vanholme, Shinya Kajita, Wout Boerjan, John Ralph. Hydroxycinnamaldehyde-derived benzofuran components in lignins.
Plant physiology.
2023 Sep; ?(?):. doi:
10.1093/plphys/kiad514. [PMID: 37773018] - Robin Huber, Laurence Marcourt, Margaux Héritier, Alexandre Luscher, Laurie Guebey, Sylvain Schnee, Emilie Michellod, Stéphane Guerrier, Jean-Luc Wolfender, Leonardo Scapozza, Thilo Köhler, Katia Gindro, Emerson Ferreira Queiroz. Generation of potent antibacterial compounds through enzymatic and chemical modifications of the trans-δ-viniferin scaffold.
Scientific reports.
2023 09; 13(1):15986. doi:
10.1038/s41598-023-43000-5. [PMID: 37749179] - Łukasz Pecio, Solomiia Pecio, Tomasz Mroczek, Wiesław Oleszek. Spiro-Flavonoids in Nature: A Critical Review of Structural Diversity and Bioactivity.
Molecules (Basel, Switzerland).
2023 Jul; 28(14):. doi:
10.3390/molecules28145420. [PMID: 37513292] - Xiaofeng Cao, Mingxia Wang, Zhong Li, Xiaoyong Xu. Synthesis, Nematicidal Evaluation, and the Structure-Activity Relationship Study of Aurone Derivatives.
Journal of agricultural and food chemistry.
2023 Jun; 71(23):8757-8768. doi:
10.1021/acs.jafc.3c00627. [PMID: 37277310] - Jinyao Xu, Xiangjun Sun, Feng Qin, Xufeng Wang, Qian Chen, Ruicheng Yan. Protective effects of salvianolic acid B on intestinal ischemia/reperfusion injury in rats by regulating the AhR/IL-22/STAT6 axis.
Journal of receptor and signal transduction research.
2023 Jun; 43(3):73-82. doi:
10.1080/10799893.2023.2204949. [PMID: 37387514] - Yanyang Liu, Jing Peng, Ling Huang, Bichen Li, Chengyu Ge, Shao Liu, Yueping Jiang. (+)-/(-)-Rutabenzofuran A and (+)-/(-)- Rutabenzofuran B: Two unprecedented pairs of Z/E isomeric benzofuran enantiomers from the aerial part of Ruta graveolens L.
Phytochemistry.
2023 Jun; 210(?):113677. doi:
10.1016/j.phytochem.2023.113677. [PMID: 37059286] - Houssem Boulebd, David M Pereira. Examination of the Antioxidant Activity of Psoralidin: Computational Mechanistic Study and Impact on the ROS Level in Human Keratinocytes.
The Journal of organic chemistry.
2023 May; 88(9):5745-5751. doi:
10.1021/acs.joc.3c00193. [PMID: 37074959] - Ning Xu, Enkhzaya Nyamdavaa, Jiaqi Yu, Hua Xiao, Jinglin Liu, Shuyan Li, Liang Xu. A new benzofuran compound from the resinous exudates of Commiphora myrrha.
Natural product research.
2023 May; 37(9):1416-1420. doi:
10.1080/14786419.2021.2011272. [PMID: 35075958] - Loreto Santa-Marina, Ziortza Barroeta, Amaia Irizar, Jon Iñaki Alvarez, Esteban Abad, Juan Muñoz-Arnanz, Begoña Jiménez, Jesús Ibarluzea, Nerea Urbieta, Alba Jimeno-Romero, Miren Begoña Zubero, Aitana Lertxundi. Characterization of PCDD/F and dl-PCB levels in air in Gipuzkoa (Basque Country, Spain).
Environmental research.
2023 Apr; 228(?):115901. doi:
10.1016/j.envres.2023.115901. [PMID: 37072078] - Chun-Kun Yang, Qing-Quan Pan, Zhuang Tian, Yan-Jun DU, Feng-Qin Sun, Jin Lu, Jun Li. [Protective mechanism of salvianolic acid B on blood vessels].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2023 Mar; 48(5):1176-1185. doi:
10.19540/j.cnki.cjcmm.20221102.707. [PMID: 37005801] - Ying Han, Wenbin Liu, Rongrong Lei, Mingxin Wang, Yingang Xue. Burden levels of polychlorinated dibenzo-p-dioxins, dibenzofurans, and polychlorinated biphenyls in typical edible meat animals.
Journal of environmental sciences (China).
2023 Mar; 125(?):742-749. doi:
10.1016/j.jes.2022.02.033. [PMID: 36375956] - Chi-Wei Huang, Wen-Yen Huang, Chitsan Lin, Yi-Lin Li, Tsung-Po Huang, Xuan-Thanh Bui, Huu Hao Ngo. Ecological risk assessment and corrective actions for dioxin-polluted sediment in a chemical plant's brine water storage pond.
The Science of the total environment.
2023 Feb; 859(Pt 1):160239. doi:
10.1016/j.scitotenv.2022.160239. [PMID: 36402325] - Yuxuan Ying, Liang Xu, Xiaoqing Lin, Hao Zhang, Xiaodong Li, Shengyong Lu, Yang Cao, Jisheng Long. Influence of different kinds of incinerators on PCDD/Fs: a case study of emission and formation pathway.
Environmental science and pollution research international.
2023 Jan; 30(3):5903-5916. doi:
10.1007/s11356-022-22437-7. [PMID: 35982393] - Yara Mahfouz, Mireille Harmouche-Karaki, Joseph Matta, Maya Mahfouz, Pascale Salameh, Hassan Younes, Khalil Helou, Ramzi Finan, Georges Abi-Tayeh, Mohamad Meslimani, Ghada Moussa, Nada Chahrour, Camille Osseiran, Farouk Skaiky, Jean-François Narbonne. Serum levels of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in a sample of Lebanese pregnant women: The role of dietary, anthropometric, and environmental factors.
Environmental research.
2023 01; 216(Pt 3):114647. doi:
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Molecules (Basel, Switzerland).
2022 Dec; 27(24):. doi:
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International journal of environmental research and public health.
2022 12; 19(24):. doi:
10.3390/ijerph192416465. [PMID: 36554346] - Yanan Li, Jie Qiu, Ping Yi, Jue Yang, Wei Gu, Yanmei Li, Chunmao Yuan, Xiaojiang Hao. Isolation and synthesis of rocaglaol derivatives by inhibiting Wnt/β-catenin and MAPK signaling pathways against colorectal cancer.
Bioorganic chemistry.
2022 Dec; 129(?):106149. doi:
10.1016/j.bioorg.2022.106149. [PMID: 36116324] - Bo Lu, Jianhua Li, MingTai Gui, Lei Yao, Mingsong Fan, Xunjie Zhou, Deyu Fu. Salvianolic acid B inhibits myocardial I/R-induced ROS generation and cell apoptosis by regulating the TRIM8/GPX1 pathway.
Pharmaceutical biology.
2022 Dec; 60(1):1458-1468. doi:
10.1080/13880209.2022.2096644. [PMID: 35968584] - Xiangzeng Wang, Yao Cao, Jiaxin Yang, Tong Zhang, Qianqian Yang, Yanhua Zhang, Donghao Wang, Xiaoyan Cao. Transcription Factor SmSPL2 Inhibits the Accumulation of Salvianolic Acid B and Influences Root Architecture.
International journal of molecular sciences.
2022 Nov; 23(21):. doi:
10.3390/ijms232113549. [PMID: 36362335] - Hanxue Wang, Min Xuan, Cheng Huang, Changhong Wang. Advances in Research on Bioactivity, Toxicity, Metabolism, and Pharmacokinetics of Usnic Acid In Vitro and In Vivo.
Molecules (Basel, Switzerland).
2022 Nov; 27(21):. doi:
10.3390/molecules27217469. [PMID: 36364296] - Lan Yao, Renjie Zhao, Shiyang He, Qi Feng, Yingjin Qiao, Pei Wang, Jun Li. Effects of salvianolic acid A and salvianolic acid B in renal interstitial fibrosis via PDGF-C/PDGFR-α signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Nov; 106(?):154414. doi:
10.1016/j.phymed.2022.154414. [PMID: 36057144] - Sheng-Lun Lin, Wei Tang, Jhong-Lin Wu, Yen-Yi Lee, Chih-Lung Wang, Wei-Hsin Chen. Particulate PCDD/F size distribution and potential deposition in respiratory system from a hazardous waste thermal treatment process.
Environmental research.
2022 11; 214(Pt 2):113806. doi:
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Fitoterapia.
2022 Nov; 163(?):105332. doi:
10.1016/j.fitote.2022.105332. [PMID: 36243242] - Lu Huang, Cheng Peng, Li Guo, Rui Feng, Hong-Zhen Shu, Yun-Cai Tian, Qin-Mei Zhou, Liang Xiong. Six pairs of enantiomeric phthalide dimers from the rhizomes of Ligusticum chuanxiong and their absolute configurations and anti-inflammatory activities.
Bioorganic chemistry.
2022 10; 127(?):105970. doi:
10.1016/j.bioorg.2022.105970. [PMID: 35749854] - Bowen Zhao, Xiude Hu, Jianyi Lu. Analysis and discussion on formation and control of dioxins generated from municipal solid waste incineration process.
Journal of the Air & Waste Management Association (1995).
2022 10; 72(10):1063-1082. doi:
10.1080/10962247.2022.2100843. [PMID: 35816420] - Ling-Cui Meng, Jia-Yi Zheng, Yu-Hui Qiu, Li Zheng, Jue-Yan Zheng, Yu-Qing Liu, Xiao-Lu Miao, Xin-Yi Lu. Salvianolic acid B ameliorates non-alcoholic fatty liver disease by inhibiting hepatic lipid accumulation and NLRP3 inflammasome in ob/ob mice.
International immunopharmacology.
2022 Oct; 111(?):109099. doi:
10.1016/j.intimp.2022.109099. [PMID: 35932615] - Baixiang Cai, Xinyin Cai, Tao Xu, Jutao Wang, Yang Yu. Structures and Anti-Inflammatory Evaluation of Phenylpropanoid Derivatives from the Aerial Parts of Dioscorea polystachya.
International journal of molecular sciences.
2022 Sep; 23(18):. doi:
10.3390/ijms231810954. [PMID: 36142867] - Lorenzo Pedroni, Luca Dellafiora, Maria Olga Varrà, Gianni Galaverna, Sergio Ghidini. In silico study on the Hepatitis E virus RNA Helicase and its inhibition by silvestrol, rocaglamide and other flavagline compounds.
Scientific reports.
2022 09; 12(1):15512. doi:
10.1038/s41598-022-19818-w. [PMID: 36109625] - Yang Liu, Xue Zhou, Dan Zhou, Yongxing Jian, Jingfu Jia, Fahuan Ge. Isolation of Chalcomoracin as a Potential α-Glycosidase Inhibitor from Mulberry Leaves and Its Binding Mechanism.
Molecules (Basel, Switzerland).
2022 Sep; 27(18):. doi:
10.3390/molecules27185742. [PMID: 36144478] - Jian Jia, Jianbing Wu, Duorui Ji, Weijie Jiao, Xiaoli Wang, Zhangjian Huang, Yihua Zhang. Synthesis and biological evaluation of hybrids from optically active ring-opened 3-N-butylphthalide derivatives and 4-fluro-edaravone as potential anti-acute ischemic stroke agents.
Bioorganic & medicinal chemistry.
2022 09; 69(?):116891. doi:
10.1016/j.bmc.2022.116891. [PMID: 35764031] - Xiu-Rong Zhang, Tao Lin, Xiu-Li Wang, Xiao-Jie Wang, Heng Gu. [Preparation of salvianolic acid B, tanshinone Ⅱ_A, and glycyrrhetinic acid lipid emulsion and its protective effect against acute liver injury induced by acetaminophen].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2022 Sep; 47(17):4634-4642. doi:
10.19540/j.cnki.cjcmm.20220705.302. [PMID: 36164869] - Cheng Qian, Chunmei Yang, Yu Tang, Weiwei Zheng, Yueke Zhou, Shan Zhang, Mengyao Song, Peng Cheng, Zhonghong Wei, Chongjin Zhong, Li Wan, Aiyun Wang, Yang Zhao, Yin Lu. Pharmacological manipulation of Ezh2 with salvianolic acid B results in tumor vascular normalization and synergizes with cisplatin and T cell-mediated immunotherapy.
Pharmacological research.
2022 08; 182(?):106333. doi:
10.1016/j.phrs.2022.106333. [PMID: 35779815] - Xiang-Lin Kong, Qin Lyu, Ya-Qi Zhang, Dong-Fang Kang, Chao Li, Lei Zhang, Zi-Chen Gao, Xin-Xin Liu, Ji-Biao Wu, Yun-Lun Li. Effect of astragaloside IV and salvianolic acid B on antioxidant stress and vascular endothelial protection in the treatment of atherosclerosis based on metabonomics.
Chinese journal of natural medicines.
2022 Aug; 20(8):601-613. doi:
10.1016/s1875-5364(22)60186-9. [PMID: 36031232] - Charlotte Driesen, Markus Zennegg, Myriam Rothacher, Sébastien Dubois, Ueli Wyss, Bernd Nowack, Sylvain Lerch. Transgenerational mass balance and tissue distribution of PCBs and PCDD/Fs from grass silage and soil into cow-calf continuum.
Chemosphere.
2022 Jul; ?(?):135745. doi:
10.1016/j.chemosphere.2022.135745. [PMID: 35863416] - Simone Samperna, Marco Masi, Maurizio Vurro, Antonio Evidente, Mauro Marra. Cyclopaldic Acid, the Main Phytotoxic Metabolite of Diplodia cupressi, Induces Programmed Cell Death and Autophagy in Arabidopsis thaliana.
Toxins.
2022 07; 14(7):. doi:
10.3390/toxins14070474. [PMID: 35878212] - Yun Wang, Xinyu Xu, Lin Lin. Prucalopride might improve intestinal motility by promoting the regeneration of the enteric nervous system in diabetic rats.
International journal of molecular medicine.
2022 Jul; 50(1):. doi:
10.3892/ijmm.2022.5143. [PMID: 35543167] - Xiu-Wei Yang, Zi-Chao He, Li-Hua Chen, Qing-Xia Xu, Wei Xu. [Biotransformation of psoralenoside and isopsoralenoside in Psoraleae Fructus incubated with human intestinal bacteria flora in vitro].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2022 Jul; 47(14):3822-3827. doi:
10.19540/j.cnki.cjcmm.20220325.201. [PMID: 35850840] - Xiaofang Liu, Yan Zhou, Xiao Liu, Sheng Wen, Wencheng Cao. [Serum polychlorinated biphenyls levels in some reproductive aged men in Wuhan and the influencing factors in 2013].
Wei sheng yan jiu = Journal of hygiene research.
2022 Jul; 51(4):610-616. doi:
10.19813/j.cnki.weishengyanjiu.2022.04.019. [PMID: 36047267] - Hong Meng, Meng-Meng Zhao, Ru-Ya Yang, Xiao-Feng Deng, Hong-Yan Zhang, Yeong-Min Choi, In-Sook An, Sung-Kwan An, Yin-Mao Dong, Yi-Fan He, Li Li, Miao-Miao Guo, Fan Yi. Salvianolic acid B regulates collagen synthesis: Indirect influence on human dermal fibroblasts through the microvascular endothelial cell pathway.
Journal of cosmetic dermatology.
2022 Jul; 21(7):3007-3015. doi:
10.1111/jocd.14516. [PMID: 34648670] - Hai-Yan Xiao, Shu-Xian Yang, Wen Han, Li Cao, Gui-Bo Sun. [Research progress on pharmacology of butylphthalide and its derivatives].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2022 Jul; 47(13):3425-3431. doi:
10.19540/j.cnki.cjcmm.20220117.701. [PMID: 35850792] - Madhuree Kumari, Siya Kamat, C Jayabaskaran. Usnic acid induced changes in biomolecules and their association with apoptosis in squamous carcinoma (A-431) cells: A flow cytometry, FTIR and DLS spectroscopic study.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2022 Jun; 274(?):121098. doi:
10.1016/j.saa.2022.121098. [PMID: 35257985] - Liu-Yan Wang, Wen-Yan Li, Hao-Feng Zhou, Xue-Yu Zhao, Xiao-Nian Li, Xing-De Wu, Qin-Shi Zhao. Spiroligustolides A and B: Two pairs of enantiomeric spiro-orthoester-containing phthalide dimers as Cav3.1 calcium channel inhibitors from Ligusticum Chuanxiong Hort.
Bioorganic chemistry.
2022 06; 123(?):105749. doi:
10.1016/j.bioorg.2022.105749. [PMID: 35364556] - Yoon-Su Ha, Taek-Kyong Kim, Ki-Sun Park, Seonghwan Hwang, Jeongkyu Kim, Seung-Jin Kim. Inhibitory effects of Rocaglamide-A on PPARγ-driven adipogenesis through regulation of mitotic clonal expansion involving the JAK2/STAT3 pathway.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2022 06; 1867(6):159148. doi:
10.1016/j.bbalip.2022.159148. [PMID: 35248800] - Juan Liu, Rui Feng, Ou Dai, Hong Ni, Lu-Si Liu, Hong-Zhen Shu, Yan Lu, Cheng Peng, Liang Xiong. Isoindolines and phthalides from the rhizomes of Ligusticum chuanxiong and their relaxant effects on the uterine smooth muscle.
Phytochemistry.
2022 Jun; 198(?):113159. doi:
10.1016/j.phytochem.2022.113159. [PMID: 35283167] - Shuai Liu, Lu Lu, Feng Pan, Chunsheng Yang, Jing Liang, Jinfeng Liu, Jian Wang, Rong Shen, Fu-Ze Xin, Nan Zhang. Real-World Data: Fruquintinib in Treating Metastatic Colorectal Cancer.
Oncology research.
2022 May; 29(1):25-31. doi:
10.3727/096504022x16427607626672. [PMID: 35063062] - Junqi Chen, Qinghong Hu, Yini Luo, Lina Luo, Hua Lin, Dandan Chen, Yuan Xu, Bihao Liu, Yu He, Chunling Liang, Yaoyu Liu, Jiuyao Zhou, Junbiao Wu. Salvianolic acid B attenuates membranous nephropathy by activating renal autophagy via microRNA-145-5p/phosphatidylinositol 3-kinase/AKT pathway.
Bioengineered.
2022 May; 13(5):13956-13969. doi:
10.1080/21655979.2022.2083822. [PMID: 35723058] - Beibei Fu, Shuqing Meng, Genshan Gao. A combination of tetramethylpyrazine hydrochloride and butylphthalide on serum S100B, CRP, Hcy levels and NIHSS score in patients with acute cerebral infarction: A retrospective study.
Pakistan journal of pharmaceutical sciences.
2022 May; 35(3(Special)):945-951. doi:
. [PMID: 35791592] - Pauline Beaumont, Arnaud Courtois, Claude Atgié, Tristan Richard, Stéphanie Krisa. In the shadow of resveratrol: biological activities of epsilon-viniferin.
Journal of physiology and biochemistry.
2022 May; 78(2):465-484. doi:
10.1007/s13105-022-00880-x. [PMID: 35312966] - Toru Nakayama. Biochemistry and regulation of aurone biosynthesis.
Bioscience, biotechnology, and biochemistry.
2022 Apr; 86(5):557-573. doi:
10.1093/bbb/zbac034. [PMID: 35259212] - Shuting Wang, Jie Bao, Jie Li, Wanfang Li, Mengyin Tian, Caixia Qiu, Fei Pang, Xin Li, Jianbo Yang, Yuchi Hu, Sujuan Wang, Hongtao Jin. Fraxinellone Induces Hepatotoxicity in Zebrafish through Oxidative Stress and the Transporters Pathway.
Molecules (Basel, Switzerland).
2022 Apr; 27(9):. doi:
10.3390/molecules27092647. [PMID: 35566003] - Su Hyun Park, Yu Jeong Jeong, Sung-Chul Park, Soyoung Kim, Yong-Goo Kim, Gilok Shin, Hyung Jae Jeong, Young Bae Ryu, Jiyoung Lee, Ok Ran Lee, Jae Cheol Jeong, Cha Young Kim. Highly Efficient Bioconversion of trans-Resveratrol to δ-Viniferin Using Conditioned Medium of Grapevine Callus Suspension Cultures.
International journal of molecular sciences.
2022 Apr; 23(8):. doi:
10.3390/ijms23084403. [PMID: 35457219] - Chu Wang, Shujun Dong, Pu Wang, Yanfen Hao, Ruiguo Wang, Qinghua Zhang, Guibin Jiang. Insights into the toxicokinetic, tissue distribution and maternal transfer of polychlorinated dibenzo-p-dioxins/dibenzofurans in laying hens fed with dioxin-associated dietary.
The Science of the total environment.
2022 Apr; 816(?):151664. doi:
10.1016/j.scitotenv.2021.151664. [PMID: 34785219] - Kitherian Sahayaraj, Poolpandi Kombiah, Jesu Antony Martin Rathi. A chalcone (Pongamol) and phytoconstituents of Tephrosia purpurea.
Natural product research.
2022 Apr; 36(7):1870-1873. doi:
10.1080/14786419.2020.1808640. [PMID: 32840388] - Jun Tan, Wei Li, Zhipeng Teng, Guang Wang, Yanyan Li, Yuan Zhang. Senkyunolide H inhibits activation of microglia and attenuates lipopolysaccharide-mediated neuroinflammation and oxidative stress in BV2 microglia cells via regulating ERK and NF-κB pathway.
The Kaohsiung journal of medical sciences.
2022 Apr; 38(4):378-384. doi:
10.1002/kjm2.12477. [PMID: 34783459] - Shuai Sun, Baoqin Zhang, Yun Luo, Xindong Ma, Rong Cao, Yichi Zhang, Yuan Gao, Jiping Chen, Haijun Zhang. Accumulation characteristics of polychlorinated dibenzo-p-dioxins and dibenzofurans and polychlorinated biphenyls in human breast milk from a seaside city of North China.
Environmental pollution (Barking, Essex : 1987).
2022 Mar; 297(?):118794. doi:
10.1016/j.envpol.2022.118794. [PMID: 34998892] - Sara J Lupton, Cristian Ochoa, Alexander Domesle, Randolph Duverna. Survey of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and non-ortho-polychlorinated biphenyls in U.S. meat, poultry, and siluriform fish from 2018-2019: toxic equivalency levels, temporal trends, and implications.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2022 Mar; 39(3):560-571. doi:
10.1080/19440049.2021.2022769. [PMID: 35113765] - Qian-Qian Wang, Meng Wang, Yan Li, Yong-Hui Liu, Lian-Qing Sun. Attenuation of Oxidative Stress-Induced Cell Apoptosis and Pyroptosis in RSC96 Cells by Salvianolic Acid B.
Chinese journal of integrative medicine.
2022 Mar; 28(3):243-248. doi:
10.1007/s11655-021-3507-2. [PMID: 35084700] - Muhammad Irfan, Tae-Hyung Kwon, Hyuk-Woo Kwon, Man Hee Rhee. Pharmacological actions of dieckol on modulation of platelet functions and thrombus formation via integrin αIIbβ3 and cAMP signaling.
Pharmacological research.
2022 Mar; 177(?):106088. doi:
10.1016/j.phrs.2022.106088. [PMID: 35038555] - Yanli Guo, Huaiqiang Hu, Guigang Xu, Yang Liu, Jinbo Yan, Hui Liu. Cerebral hemodynamic changes assessment by transcranial doppler ultrasound in patients with acute cerebral infarction before and after treatment with butylphthalide.
Pakistan journal of pharmaceutical sciences.
2022 Mar; 35(2(Special)):613-618. doi:
. [PMID: 35668561] - Yingpeng Xu, Lijun Geng, Yiwen Zhang, J Andrew Jones, Meihong Zhang, Yuan Chen, Ronghui Tan, Mattheos A G Koffas, Zhengtao Wang, Shujuan Zhao. De novo Biosynthesis of Salvianolic Acid B in Saccharomyces cerevisiae Engineered with the Rosmarinic Acid Biosynthetic Pathway.
Journal of agricultural and food chemistry.
2022 Feb; 70(7):2290-2302. doi:
10.1021/acs.jafc.1c06329. [PMID: 35157428] - Ping-Chin Lai, Cheng-Hsu Chen, Long-Bin Jeng, Tung-Min Yu, Shang-Feng Tsai, Ming-Ju Wu, Shao-Bin Cheng, Sheng-Shun Yang, Teng-Yu Lee. Grazoprevir/Elbasvir Treatment in Liver or Kidney Transplant Recipients with Genotype 1b Hepatitis C Virus Infection.
Antimicrobial agents and chemotherapy.
2022 02; 66(2):e0200321. doi:
10.1128/aac.02003-21. [PMID: 34902265] - Zhiyun Ji, Binbin Huang, Min Gan, Xiaohui Fan, Guojing Wang, Qianqian Zhao, Jinxin Xing, Ruirui Yuan. Dioxins control as co-processing water-washed municipal solid waste incineration fly ash in iron ore sintering process.
Journal of hazardous materials.
2022 02; 423(Pt B):127138. doi:
10.1016/j.jhazmat.2021.127138. [PMID: 34537647] - Sheng-Lun Lin, Jhong-Lin Wu, Wei-Hsin Chen, Han Wu, Wei Tang. Ultra-low PCDD/F emissions and their particle size and mass distribution in a hazardous waste treatment system.
Journal of hazardous materials.
2022 02; 423(Pt A):127032. doi:
10.1016/j.jhazmat.2021.127032. [PMID: 34474365] - Pasqualina Liana Scognamiglio, Caterina Vicidomini, Francesco Fontanella, Claudio De Stefano, Rosanna Palumbo, Giovanni N Roviello. Protein Binding of Benzofuran Derivatives: A CD Spectroscopic and In Silico Comparative Study of the Effects of 4-Nitrophenyl Functionalized Benzofurans and Benzodifurans on BSA Protein Structure.
Biomolecules.
2022 02; 12(2):. doi:
10.3390/biom12020262. [PMID: 35204762] - Agnieszka Pyrczak-Felczykowska, Tristan A Reekie, Marcin Jąkalski, Aleksandra Hać, Marcelina Malinowska, Anna Pawlik, Kamil Ryś, Beata Guzow-Krzemińska, Anna Herman-Antosiewicz. The Isoxazole Derivative of Usnic Acid Induces an ER Stress Response in Breast Cancer Cells That Leads to Paraptosis-like Cell Death.
International journal of molecular sciences.
2022 Feb; 23(3):. doi:
10.3390/ijms23031802. [PMID: 35163724] - Jie Xiang, Chunling Zhang, Tietao Di, Lu Chen, Wei Zhao, Lianggang Wei, Shiyong Zhou, Xueli Wu, Gengxin Wang, Yun Zhang. Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells.
Bioengineered.
2022 02; 13(2):3486-3502. doi:
10.1080/21655979.2022.2026552. [PMID: 35068334] - Eiki Kimura, Go Suzuki, Naoto Uramaru, Masaki Kakeyama, Fumihiko Maekawa. Liver-specific decrease in Tff3 gene expression in infant mice perinatally exposed to 2,3,7,8-tetrabromodibenzofuran or 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Journal of applied toxicology : JAT.
2022 02; 42(2):305-317. doi:
10.1002/jat.4220. [PMID: 34254344] - Jocelyn Fuentes, Oscar Brunser, Elías Atala, José Herranz, Adriano Costa de Camargo, Hermann Zbinden-Foncea, Hernán Speisky. Protection against indomethacin-induced loss of intestinal epithelial barrier function by a quercetin oxidation metabolite present in onion peel: In vitro and in vivo studies.
The Journal of nutritional biochemistry.
2022 02; 100(?):108886. doi:
10.1016/j.jnutbio.2021.108886. [PMID: 34670110] - Chaoqun Lin, Shiying Huang, Jianfeng Zhang, Huaitao Yuan, Tuchao Yao, Lukui Chen. Dl-3-N-Butylphthalide Attenuates Hypoxic Injury of Neural Stem Cells by Increasing Hypoxia-Inducible Factor-1alpha.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.
2022 Feb; 31(2):106221. doi:
10.1016/j.jstrokecerebrovasdis.2021.106221. [PMID: 34837757] - Jing Chen, Yingchao Wang, Shufang Wang, Xiaoping Zhao, Lu Zhao, Yi Wang. Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling.
Journal of ethnopharmacology.
2022 Jan; 283(?):114667. doi:
10.1016/j.jep.2021.114667. [PMID: 34597652] - Debanjan Sen, Bimal Debnath, Pradip Debnath, Sudhan Debnath, Magdi E A Zaki, Vijay H Masand. Identification of potential edible mushroom as SARS-CoV-2 main protease inhibitor using rational drug designing approach.
Scientific reports.
2022 01; 12(1):1503. doi:
10.1038/s41598-022-05349-x. [PMID: 35087077]