2-Methoxyethanol (BioDeep_00000173346)
Secondary id: BioDeep_00000753501
human metabolite PANOMIX_OTCML-2023 blood metabolite BioNovoGene_Lab2019
代谢物信息卡片
化学式: C3H8O2 (76.0524268)
中文名称: 乙二醇甲醚, 2-甲氧基乙醇
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 80%
分子结构信息
SMILES: COCCO
InChI: InChI=1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
描述信息
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
D009676 - Noxae > D013723 - Teratogens
同义名列表
20 个代谢物同义名
Carbowax sentry methoxypolyethylene glycol; Methyl cellosolve, potassium salt; Ethylene glycol monomethyl ether; Monomethyl ethylene glycol ether; Methyl cellosolve, calcium salt; Methyl cellosolve, sodium salt; 2-Hydroxyethyl methyl ether; Methoxy polyethylene glycol; 1-Hydroxy-2-methoxyethane; beta-Methoxyethanol; 2-Methoxy-1-ethanol; 2-methoxyethan-1-ol; Methyl cellosolve; b-Methoxyethanol; 2-methoxyethanol; Methylcellosolve; Β-methoxyethanol; 3-Oxa-1-butanol; Methyl oxitol; HOCH2CH2OCH3
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:46790
- ChEBI: CHEBI:53449
- PubChem: 8019
- HMDB: HMDB0245203
- DrugBank: DB02806
- ChEMBL: CHEMBL444144
- Wikipedia: 2-Methoxyethanol
- MetaCyc: 2-METHOXYETHANOL
- chemspider: 7728
- CAS: 109-86-4
- RefMet: 2-Methoxyethanol
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-343
分类词条
相关代谢途径
Reactome(0)
BioCyc(3)
PlantCyc(3)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Reo Kawata, Takumi Kagawa, Yoshihiro Koya, Hiroaki Kajiyama, Shingo Oda, Tsuyoshi Yokoi. Exploration of small RNA biomarkers for testicular injury in the serum exosomes of rats.
Toxicology.
2020 07; 440(?):152490. doi:
10.1016/j.tox.2020.152490
. [PMID: 32418910] - Douglas J Fort, Michael B Mathis, Patrick D Guiney, John A Weeks. Inhibition of germinal vesicle breakdown in Xenopus oocytes in vitro by a series of substituted glycol ethers.
Journal of applied toxicology : JAT.
2018 05; 38(5):628-637. doi:
10.1002/jat.3567
. [PMID: 29205417] - E Fabian, N Bordag, M Herold, H Kamp, G Krennrich, R Looser, L Ma-Hock, W Mellert, G Montoya, E Peter, A Prokudin, M Spitzer, V Strauss, T Walk, R Zbranek, B van Ravenzwaay. Metabolite profiles of rats in repeated dose toxicological studies after oral and inhalative exposure.
Toxicology letters.
2016 Jul; 255(?):11-23. doi:
10.1016/j.toxlet.2016.05.003
. [PMID: 27153797] - Yoshikazu Taketa, Kaoru Inoue, Miwa Takahashi, Yohei Sakamoto, Gen Watanabe, Kazuyoshi Taya, Midori Yoshida. Effects of sulpiride and ethylene glycol monomethyl ether on endometrial carcinogenicity in Donryu rats.
Journal of applied toxicology : JAT.
2016 Jun; 36(6):769-76. doi:
10.1002/jat.3206
. [PMID: 26178146] - Ken Sakurai, Kei Mikamoto, Makoto Shirai, Takuma Iguchi, Kazumi Ito, Wataru Takasaki, Kazuhiko Mori. MicroRNA profiling in ethylene glycol monomethyl ether-induced monkey testicular toxicity model.
The Journal of toxicological sciences.
2015 Jun; 40(3):375-82. doi:
10.2131/jts.40.375
. [PMID: 25972197] - Beata Starek-Świechowicz, Katarzyna Miranowicz-Dzierżawska, Bogusława Budziszewska, Andrzej Starek. The effects of 2-methoxyethanol and 2-ethoxyethanol on hematological changes induced by 2-butoxyethanol.
Medycyna pracy.
2015; 66(3):303-15. doi:
10.13075/mp.5893.00126
. [PMID: 26325043] - Yoshikazu Taketa, Kaoru Inoue, Miwa Takahashi, Jyoji Yamate, Midori Yoshida. Differential morphological effects in rat corpora lutea among ethylene glycol monomethyl ether, atrazine, and bromocriptine.
Toxicologic pathology.
2013 Jul; 41(5):736-43. doi:
10.1177/0192623312464305
. [PMID: 23076038] - Brian P Enright, Belen Tornesi, Helga Lorenz, Katharine Whitney. The inhibin B response to testicular toxicants ethylene glycol monomethyl ether or dibromoacetic acid in male rats.
Birth defects research. Part B, Developmental and reproductive toxicology.
2013 Feb; 98(1):35-40. doi:
10.1002/bdrb.21039
. [PMID: 23348848] - Bartosz Pomierny, Andrzej Starek, Weronika Krzyżanowska, Beata Starek-Swiechowicz, Irena Smaga, Lucyna Pomierny-Chamioło, Magdalena Regulska, Bogusława Budziszewska. Potential neurotoxic effect of ethylene glycol ethers mixtures.
Pharmacological reports : PR.
2013; 65(5):1415-21. doi:
10.1016/s1734-1140(13)71501-9
. [PMID: 24399739] - John E Casida. The greening of pesticide-environment interactions: some personal observations.
Environmental health perspectives.
2012 Apr; 120(4):487-93. doi:
10.1289/ehp.1104405
. [PMID: 22472325] - Husam S Younis, Jeff Crosby, Jung-Im Huh, Hong Soo Lee, Soyub Rime, Brett Monia, Scott P Henry. Antisense inhibition of coagulation factor XI prolongs APTT without increased bleeding risk in cynomolgus monkeys.
Blood.
2012 Mar; 119(10):2401-8. doi:
10.1182/blood-2011-10-387134
. [PMID: 22246038] - Lianghua Chen, Ying Han, Hao Jiang, Helena Korpelainen, Chunyang Li. Nitrogen nutrient status induces sexual differences in responses to cadmium in Populus yunnanensis.
Journal of experimental botany.
2011 Oct; 62(14):5037-50. doi:
10.1093/jxb/err203
. [PMID: 21778178] - Nicholas Jb Brereton, Frederic E Pitre, Michael J Ray, Angela Karp, Richard J Murphy. Investigation of tension wood formation and 2,6-dichlorbenzonitrile application in short rotation coppice willow composition and enzymatic saccharification.
Biotechnology for biofuels.
2011 May; 4(?):13. doi:
10.1186/1754-6834-4-13
. [PMID: 21609446] - Didik Priyandoko, Tetsuro Ishii, Sunil C Kaul, Renu Wadhwa. Ashwagandha leaf derived withanone protects normal human cells against the toxicity of methoxyacetic acid, a major industrial metabolite.
PloS one.
2011 May; 6(5):e19552. doi:
10.1371/journal.pone.0019552
. [PMID: 21573189] - Makoto Takei, Yosuke Ando, Wataru Saitoh, Tomoe Tanimoto, Naoki Kiyosawa, Sunao Manabe, Atsushi Sanbuissho, Osamu Okazaki, Haruo Iwabuchi, Takashi Yamoto, Klaus-Peter Adam, James E Weiel, John A Ryals, Michael V Milburn, Lining Guo. Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family.
Toxicological sciences : an official journal of the Society of Toxicology.
2010 Dec; 118(2):643-52. doi:
10.1093/toxsci/kfq211
. [PMID: 20616209] - Mi-Ok Shin, Jeon-Ok Moon. Effect of dietary supplementation of grape skin and seeds on liver fibrosis induced by dimethylnitrosamine in rats.
Nutrition research and practice.
2010 Oct; 4(5):369-74. doi:
10.4162/nrp.2010.4.5.369
. [PMID: 21103082] - Hui Zhang, Wanqi Liang, Xijia Yang, Xue Luo, Ning Jiang, Hong Ma, Dabing Zhang. Carbon starved anther encodes a MYB domain protein that regulates sugar partitioning required for rice pollen development.
The Plant cell.
2010 Mar; 22(3):672-89. doi:
10.1105/tpc.109.073668
. [PMID: 20305120] - Donovan P German, Rosalie A Bittong. Digestive enzyme activities and gastrointestinal fermentation in wood-eating catfishes.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology.
2009 Nov; 179(8):1025-42. doi:
10.1007/s00360-009-0383-z
. [PMID: 19568757] - Rajeev Bhat, H P S A Khalil, A A Karim. Exploring the antioxidant potential of lignin isolated from black liquor of oil palm waste.
Comptes rendus biologies.
2009 Sep; 332(9):827-31. doi:
10.1016/j.crvi.2009.05.004
. [PMID: 19748457] - Donovan P German. Do herbivorous minnows have 'plug-flow reactor' guts? Evidence from digestive enzyme activities, gastrointestinal fermentation, and luminal nutrient concentrations.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology.
2009 Aug; 179(6):759-71. doi:
10.1007/s00360-009-0359-z
. [PMID: 19363616] - Maria Lundmark, Vaughan Hurry, Line Lapointe. Low temperature maximizes growth of Crocus vernus (L.) Hill via changes in carbon partitioning and corm development.
Journal of experimental botany.
2009; 60(7):2203-13. doi:
10.1093/jxb/erp103
. [PMID: 19403850] - Pascale Peyron, Julien Vaubourgeix, Yannick Poquet, Florence Levillain, Catherine Botanch, Fabienne Bardou, Mamadou Daffé, Jean-François Emile, Bruno Marchou, Pere-Joan Cardona, Chantal de Chastellier, Frédéric Altare. Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence.
PLoS pathogens.
2008 Nov; 4(11):e1000204. doi:
10.1371/journal.ppat.1000204
. [PMID: 19002241] - Yasutaka Sasaki, Kimiyasu Isobe, Michihiko Kataoka, Jun Ogawa, Akira Iwasaki, Junzo Hasegawa, Sakayu Shimizu. Purification and characterization of a new aldehyde oxidase from pseudomonas sp. AIU 362.
Journal of bioscience and bioengineering.
2008 Sep; 106(3):297-302. doi:
10.1263/jbb.106.297
. [PMID: 18930009] - Maiko Katadae, Ken'ichi Hagiwara, Akimori Wada, Masayoshi Ito, Masato Umeda, Patrick J Casey, Yoshitaka Fukada. Interacting targets of the farnesyl of transducin gamma-subunit.
Biochemistry.
2008 Aug; 47(32):8424-33. doi:
10.1021/bi800359h
. [PMID: 18636747] - Anna Maria Piras, Federica Chiellini, Chiara Fiumi, Cristina Bartoli, Emo Chiellini, Bruno Fiorentino, Claudio Farina. A new biocompatible nanoparticle delivery system for the release of fibrinolytic drugs.
International journal of pharmaceutics.
2008 Jun; 357(1-2):260-71. doi:
10.1016/j.ijpharm.2008.01.035
. [PMID: 18313868] - Saïd Jebors, Fabienne Fache, Sylvain Balme, Floriane Devoge, Melany Monachino, Sebastien Cecillon, Anthony W Coleman. Designer amphiphiles based on para-acyl-calix[8]arenes.
Organic & biomolecular chemistry.
2008 Jan; 6(2):319-29. doi:
10.1039/b713883k
. [PMID: 18175001] - Tamanna Jahangir, Sarwat Sultana. Perillyl Alcohol Protects Against Fe-NTA-Induced Nephrotoxicity and Early Tumor Promotional Events in Rat Experimental Model.
Evidence-based complementary and alternative medicine : eCAM.
2007 Dec; 4(4):439-45. doi:
10.1093/ecam/nel104
. [PMID: 18227911] - H-Y Chang, C-C Lin, T-S Shih, H Chan, J-S Chou, Y-S Huang. Evaluation of the protective effectiveness of gloves from occupational exposure to 2-methoxyethanol using the biomarkers of 2-methoxyacetic acid levels in the urine and plasma.
Occupational and environmental medicine.
2004 Aug; 61(8):697-702. doi:
10.1136/oem.2003.011171
. [PMID: 15258277] - Ching-Hui Loh, Tung-Sheng Shih, An-Tsz Hsieh, Yeong-Hwang Chen, Guo-Dong Liao, Saou-Hsing Liou. Hepatic effects in workers exposed to 2-methoxy ethanol.
Journal of occupational and environmental medicine.
2004 Jul; 46(7):707-13. doi:
10.1097/01.jom.0000131785.15184.c5
. [PMID: 15247810] - David C Warhurst, John C Craig, Ipemida S Adagu, David J Meyer, Sylvia Y Lee. The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids.
Malaria journal.
2003 Sep; 2(?):26. doi:
10.1186/1475-2875-2-26
. [PMID: 14505493] - Frédéric Destaillats, Paul Angers. Base-catalyzed derivatization methodology for FA analysis. application to milk fat and celery seed lipid TAG.
Lipids.
2002 May; 37(5):527-32. doi:
10.1007/s11745-002-0928-9
. [PMID: 12056597] - T Jindo, R N Wine, L H Li, R E Chapin. Protein kinase activity is central to rat germ cell apoptosis induced by methoxyacetic acid.
Toxicologic pathology.
2001 Nov; 29(6):607-16. doi:
10.1080/019262301753385933
. [PMID: 11794376] - K L Cheever, T F Swearengin, R M Edwards, B K Nelson, D W Werren, D L Conover, D G DeBord. 2-Methoxyethanol metabolism, embryonic distribution, and macromolecular adduct formation in the rat: the effect of radiofrequency radiation-induced hyperthermia.
Toxicology letters.
2001 May; 122(1):53-67. doi:
10.1016/s0378-4274(01)00346-0
. [PMID: 11397557] - T S Shih, S H Liou, C Y Chen, T J Smith. Urinary 2-methoxy acetic acid accumulation in response to 2-methoxy ethanol exposure.
Archives of environmental health.
2001 Jan; 56(1):20-5. doi:
10.1080/00039890109604050
. [PMID: 11256852] - J A Timbrell. Urinary creatine as a biochemical marker of chemical induced testicular damage.
Arhiv za higijenu rada i toksikologiju.
2000 Sep; 51(3):295-303. doi:
NULL
. [PMID: 11148934] - M L Gargas, T R Tyler, L M Sweeney, R A Corley, K K Weitz, T J Mast, D J Paustenbach, S M Hays. A toxicokinetic study of inhaled ethylene glycol monomethyl ether (2-ME) and validation of a physiologically based pharmacokinetic model for the pregnant rat and human.
Toxicology and applied pharmacology.
2000 May; 165(1):53-62. doi:
10.1006/taap.2000.8928
. [PMID: 10814553] - S M Hays, B A Elswick, G M Blumenthal, F Welsch, R B Conolly, M L Gargas. Development of a physiologically based pharmacokinetic model of 2-methoxyethanol and 2-methoxyacetic acid disposition in pregnant rats.
Toxicology and applied pharmacology.
2000 Feb; 163(1):67-74. doi:
10.1006/taap.1999.8836
. [PMID: 10662606] - T Berger, M G Miller, C M Horner. In vitro fertilization after in vivo treatment of rats with three reproductive toxicants.
Reproductive toxicology (Elmsford, N.Y.).
2000 Jan; 14(1):45-53. doi:
10.1016/s0890-6238(99)00062-3
. [PMID: 10689202] - T S Shih, S H Liou, C Y Chen, J S Chou. Correlation between urinary 2-methoxy acetic acid and exposure of 2-methoxy ethanol.
Occupational and environmental medicine.
1999 Oct; 56(10):674-8. doi:
10.1136/oem.56.10.674
. [PMID: 10658546] - L Aasmoe, J Aarbakke. Gender difference in the elimination of 2-methoxyethanol, methoxyacetic acid and ethoxyacetic acid in rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1997 Dec; 27(12):1237-44. doi:
10.1080/004982597239822
. [PMID: 9460229] - NULL. Reproductive toxicology. Ethylene glycol monomethyl ether: litter two.
Environmental health perspectives.
1997 Feb; 105 Suppl 1(?):393-5. doi:
NULL
. [PMID: 9114377] - NULL. Reproductive toxicology. Ethylene glycol monomethyl ether.
Environmental health perspectives.
1997 Feb; 105 Suppl 1(?):383-4. doi:
NULL
. [PMID: 9114373] - B J Davis, J L Almekinder, N Flagler, G Travlos, R Wilson, R R Maronpot. Ovarian luteal cell toxicity of ethylene glycol monomethyl ether and methoxy acetic acid in vivo and in vitro.
Toxicology and applied pharmacology.
1997 Feb; 142(2):328-37. doi:
10.1006/taap.1996.8035
. [PMID: 9070356] - NULL. Reproductive toxicology. Ethylene glycol monomethyl ether.
Environmental health perspectives.
1997 Feb; 105 Suppl 1(?):385-6. doi:
NULL
. [PMID: 9114374] - NULL. Reproductive toxicology. Ethylene glycol monomethyl ether: litter five.
Environmental health perspectives.
1997 Feb; 105 Suppl 1(?):389-91. doi:
NULL
. [PMID: 9114376] - S Kezić, K Mahieu, A C Monster, F A de Wolff. Dermal absorption of vaporous and liquid 2-methoxyethanol and 2-ethoxyethanol in volunteers.
Occupational and environmental medicine.
1997 Jan; 54(1):38-43. doi:
10.1136/oem.54.1.38
. [PMID: 9072032] - R P Draper, J A Timbrell. Urinary creatine as a potential marker of testicular damage: effect of vasectomy.
Reproductive toxicology (Elmsford, N.Y.).
1996 Jan; 10(1):79-85. doi:
10.1016/0890-6238(95)02021-7
. [PMID: 8998389] - G Morel, A M Lambert, B Rieger, I Subra. Interactive effect of combined exposure to glycol ethers and alcohols on toxicodynamic and toxicokinetic parameters.
Archives of toxicology.
1996; 70(8):519-25. doi:
10.1007/s002040050309
. [PMID: 8783818] - S J Sumner, D B Stedman, S Y Cheng, F Welsch, T R Fennell. Dose effects on the excretion of urinary metabolites of 2-[1,2,methoxy-13C]methoxyethanol in rats and mice.
Toxicology and applied pharmacology.
1995 Sep; 134(1):139-47. doi:
10.1006/taap.1995.1177
. [PMID: 7676448] - M Butterworth, D Creasy, J A Timbrell. The detection of subchronic testicular damage using urinary creatine: studies with 2-methoxyethanol.
Archives of toxicology.
1995; 69(3):209-11. doi:
10.1007/s002040050160
. [PMID: 7717879] - V V Turov, V A Pokrovskiĭ, A A Chuĭko. [The effect of serum albumin on the temperature of eutectic formation in binary solutions of organic compounds].
Biofizika.
1994 Nov; 39(6):988-92. doi:
NULL
. [PMID: 7873639] - K K Terry, B A Elswick, D B Stedman, F Welsch. Developmental phase alters dosimetry-teratogenicity relationship for 2-methoxyethanol in CD-1 mice.
Teratology.
1994 Mar; 49(3):218-27. doi:
10.1002/tera.1420490318
. [PMID: 8059429] - A E Ahmed, S Jacob, W W Au. Quantitative whole body autoradiographic disposition of glycol ether in mice: effect of route of administration.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1994 Feb; 22(2):266-76. doi:
10.1006/faat.1994.1030
. [PMID: 8005378] - D O Clarke, B A Elswick, F Welsch, R B Conolly. Pharmacokinetics of 2-methoxyethanol and 2-methoxyacetic acid in the pregnant mouse: a physiologically based mathematical model.
Toxicology and applied pharmacology.
1993 Aug; 121(2):239-52. doi:
10.1006/taap.1993.1151
. [PMID: 8346541] - K S Khera. Mouse placenta: hemodynamics in the main maternal vessel and histopathologic changes induced by 2-methoxyethanol and 2-methoxyacetic acid following maternal dosing.
Teratology.
1993 Apr; 47(4):299-310. doi:
10.1002/tera.1420470407
. [PMID: 8322224] - K Nahas, J L le Net, J P Provost, K E Tomaszewski. An investigation of urinary creatine excretion as a potential marker for testicular damage.
Human & experimental toxicology.
1993 Mar; 12(2):173-6. doi:
10.1177/096032719301200214
. [PMID: 8096718] - T Kawamoto, K Matsuno, F Kayama, K Arashidani, M Yoshikawa, Y Kodama. The effect of ethylene glycol monomethyl ether and diethylene glycol monomethyl ether on hepatic gamma-glutamyl transpeptidase.
Toxicology.
1992 Nov; 76(1):49-57. doi:
10.1016/0300-483x(92)90017-9
. [PMID: 1362012] - R W Tyl, L C Fisher, M F Kubena, M A Vrbanic, R Gingell, D Guest, J R Hodgson, S R Murphy, T R Tyler, B D Astill. The developmental toxicity of 2-ethylhexanol applied dermally to pregnant Fischer 344 rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1992 Aug; 19(2):176-85. doi:
10.1016/0272-0590(92)90149-c
. [PMID: 1516773] - S C Sumner, D B Stedman, D O Clarke, F Welsch, T R Fennell. Characterization of urinary metabolites from [1,2,methoxy-13C]-2-methoxyethanol in mice using 13C nuclear magnetic resonance spectroscopy.
Chemical research in toxicology.
1992 Jul; 5(4):553-60. doi:
10.1021/tx00028a015
. [PMID: 1391622] - P J Sabourin, M A Medinsky, F Thurmond, L S Birnbaum, R F Henderson. Effect of dose on the disposition of methoxyethanol, ethoxyethanol, and butoxyethanol administered dermally to male F344/N rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1992 Jul; 19(1):124-32. doi:
10.1016/0272-0590(92)90036-h
. [PMID: 1397793] - D O Clarke, J M Duignan, F Welsch. 2-Methoxyacetic acid dosimetry-teratogenicity relationships in CD-1 mice exposed to 2-methoxyethanol.
Toxicology and applied pharmacology.
1992 May; 114(1):77-87. doi:
10.1016/0041-008x(92)90099-e
. [PMID: 1585375] - C A Mebus, D O Clarke, D B Stedman, F Welsch. 2-Methoxyethanol metabolism in pregnant CD-1 mice and embryos.
Toxicology and applied pharmacology.
1992 Jan; 112(1):87-94. doi:
10.1016/0041-008x(92)90283-x
. [PMID: 1733052] - D O Clarke, C A Mebus, F J Miller, F Welsch. Protection against 2-methoxyethanol-induced teratogenesis by serine enantiomers: studies of potential alteration of 2-methoxyethanol pharmacokinetics.
Toxicology and applied pharmacology.
1991 Sep; 110(3):514-26. doi:
10.1016/0041-008x(91)90051-f
. [PMID: 1949018] - S C Reader, C Shingles, M D Stonard. Acute testicular toxicity of 1,3-dinitrobenzene and ethylene glycol monomethyl ether in the rat: evaluation of biochemical effect markers and hormonal responses.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1991 Jan; 16(1):61-70. doi:
10.1016/0272-0590(91)90135-q
. [PMID: 1902188] - M A Medinsky, G Singh, W E Bechtold, J A Bond, P J Sabourin, L S Birnbaum, R F Henderson. Disposition of three glycol ethers administered in drinking water to male F344/N rats.
Toxicology and applied pharmacology.
1990 Mar; 102(3):443-55. doi:
10.1016/0041-008x(90)90040-2
. [PMID: 2107602] - J Angerer, E Lichterbeck, J Begerow, S Jekel, G Lehnert. Occupational chronic exposure to organic solvents. XIII. Glycolether exposure during the production of varnishes.
International archives of occupational and environmental health.
1990; 62(2):123-6. doi:
10.1007/bf00383588
. [PMID: 2323830] - W J Scott, R Fradkin, W Wittfoht, H Nau. Teratologic potential of 2-methoxyethanol and transplacental distribution of its metabolite, 2-methoxyacetic acid, in non-human primates.
Teratology.
1989 Apr; 39(4):363-73. doi:
10.1002/tera.1420390408
. [PMID: 2749579] - L Rawcliffe, D Creasy, J A Timbrell. Urinary creatine as a possible marker for testicular damage: studies with the testicular toxic compound 2-methoxyethanol.
Reproductive toxicology (Elmsford, N.Y.).
1989; 3(4):269-74. doi:
10.1016/0890-6238(89)90021-x
. [PMID: 2520530] - D B Stedman, F Welsch. Inhibition of DNA synthesis in mouse whole embryo culture by 2-methoxyacetic acid and attenuation of the effects by simple physiological compounds.
Toxicology letters.
1989 Jan; 45(1):111-7. doi:
10.1016/0378-4274(89)90165-3
. [PMID: 2464863] - D Groeseneken, H Veulemans, R Masschelein, E Van Vlem. An improved method for the determination in urine of alkoxyacetic acids.
International archives of occupational and environmental health.
1989; 61(4):249-54. doi:
10.1007/bf00381422
. [PMID: 2722248] - K P Lee, L A Kinney. The ultrastructure and reversibility of testicular atrophy induced by ethylene glycol monomethyl ether (EGME) in the rat.
Toxicologic pathology.
1989; 17(4 Pt 2):759-73. doi:
10.1177/0192623389017004204
. [PMID: 2626667] - R B Sleet, J A Greene, F Welsch. The relationship of embryotoxicity to disposition of 2-methoxyethanol in mice.
Toxicology and applied pharmacology.
1988 Apr; 93(2):195-207. doi:
10.1016/0041-008x(88)90120-2
. [PMID: 3358259] - L S Welch, S M Schrader, T W Turner, M R Cullen. Effects of exposure to ethylene glycol ethers on shipyard painters: II. Male reproduction.
American journal of industrial medicine.
1988; 14(5):509-26. doi:
10.1002/ajim.4700140503
. [PMID: 3228067] - D M Creasy, L M Beech, T J Gray, W H Butler. An ultrastructural study of ethylene glycol monomethyl ether-induced spermatocyte injury in the rat.
Experimental and molecular pathology.
1986 Dec; 45(3):311-22. doi:
10.1016/0014-4800(86)90020-1
. [PMID: 3792514] - M Toraason, R W Niemeier, B D Hardin. Calcium homeostasis in pregnant rats treated with ethylene glycol monomethyl ether (EGME).
Toxicology and applied pharmacology.
1986 Nov; 86(2):197-203. doi:
10.1016/0041-008x(86)90050-5
. [PMID: 3787620] - Y Suketa, K Nishimura, H Nakajima, M Ueda, S Okada. Increment of prostaglandin E2 in association with elevation of urinary sodium excretion following lead administration.
Toxicology letters.
1986 Sep; 32(3):221-6. doi:
10.1016/0378-4274(86)90111-6
. [PMID: 3022428] - D W Hobson, A P D'Addario, R H Bruner, D E Uddin. A subchronic dermal exposure study of diethylene glycol monomethyl ether and ethylene glycol monomethyl ether in the male guinea pig.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1986 Feb; 6(2):339-48. doi:
10.1016/0272-0590(86)90249-6
. [PMID: 3699323] - E J Moss, L V Thomas, M W Cook, D G Walters, P M Foster, D M Creasy, T J Gray. The role of metabolism in 2-methoxyethanol-induced testicular toxicity.
Toxicology and applied pharmacology.
1985 Jul; 79(3):480-9. doi:
10.1016/0041-008x(85)90145-0
. [PMID: 4035689] - A W Smallwood, K E DeBord, L K Lowry. Analyses of ethylene glycol monoalkyl ethers and their proposed metabolites in blood and urine.
Environmental health perspectives.
1984 Aug; 57(?):249-53. doi:
10.1289/ehp.8457249
. [PMID: 6499809] - P M Foster, D M Creasy, J R Foster, T J Gray. Testicular toxicity produced by ethylene glycol monomethyl and monoethyl ethers in the rat.
Environmental health perspectives.
1984 Aug; 57(?):207-17. doi:
10.1289/ehp.8457207
. [PMID: 6499806] - R R Miller, E A Hermann, P W Langvardt, M J McKenna, B A Schwetz. Comparative metabolism and disposition of ethylene glycol monomethyl ether and propylene glycol monomethyl ether in male rats.
Toxicology and applied pharmacology.
1983 Feb; 67(2):229-37. doi:
10.1016/0041-008x(83)90229-6
. [PMID: 6836577] - R R Miller, J A Ayres, J T Young, M J McKenna. Ethylene glycol monomethyl ether. I. Subchronic vapor inhalation study with rats and rabbits.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1983 Jan; 3(1):49-54. doi:
10.1016/s0272-0590(83)80172-9
. [PMID: 6884623] - R R Cook, K M Bodner, R C Kolesar, C S Uhlmann, P F VanPeenen, G S Dickson, K Flanagan. A cross-sectional study of ethylene glycol monomethyl ether process employees.
Archives of environmental health.
1982 Nov; 37(6):346-51. doi:
10.1080/00039896.1982.10667589
. [PMID: 6983865] - T Heinonen, H Vainio. Dose-dependent toxicity of ethylene glycol monomethyl ether vapour in the rat.
European journal of drug metabolism and pharmacokinetics.
1981; 6(4):275-80. doi:
10.1007/bf03189526
. [PMID: 6800797]