2-Hydroxyquinoxaline (BioDeep_00000173316)

   

human metabolite blood metabolite


代谢物信息卡片


1,2-dihydroquinoxalin-2-one

化学式: C8H6N2O (146.0480106)
中文名称: 2-喹羟基噁啉, 2-羟基喹喔啉
谱图信息: 最多检出来源 Homo sapiens(blood) 50%

分子结构信息

SMILES: C1=CC=C2C(=C1)NC(=O)C=N2
InChI: InChI=1S/C8H6N2O/c11-8-5-9-6-3-1-2-4-7(6)10-8/h1-5H,(H,10,11)

描述信息

同义名列表

7 个代谢物同义名

1,2-dihydroquinoxalin-2-one; 2-BROMO-6-ETHOXY-PYRIDINE; 2-Hydroxyquinoxaline; quinoxaline-2-one; Quinoxalin-2-one; 2-Quinoxalinol; 2-Quinoxinol



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Limin Yang, Juan Han, Wei Liu, Jiqiang Li, Lei Jiang. Conversion of inhibition biosensing to substrate-like biosensing for quinalphos selective detection. Analytical chemistry. 2015 May; 87(10):5270-7. doi: 10.1021/acs.analchem.5b00376. [PMID: 25921798]
  • Bina Gupta, Manviri Rani, Rajani Salunke, Rahul Kumar. In vitro and in vivo studies on degradation of quinalphos in rats. Journal of hazardous materials. 2012 Apr; 213-214(?):285-91. doi: 10.1016/j.jhazmat.2012.01.089. [PMID: 22356742]
  • Laura Else, Victoria Watson, John Tjia, Andrew Hughes, Marco Siccardi, Saye Khoo, David Back. Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Jun; 878(19):1455-65. doi: 10.1016/j.jchromb.2010.03.036. [PMID: 20427248]
  • J Ni, J Rowe, T Heidelbaugh, S Sinha, A Acheampong. Characterization of benzimidazole and other oxidative and conjugative metabolites of brimonidine in vitro and in rats in vivo using on-line HID exchange LC-MS/MS and stable-isotope tracer techniques. Xenobiotica; the fate of foreign compounds in biological systems. 2007 Feb; 37(2):205-20. doi: 10.1080/00498250601047897. [PMID: 17484522]
  • Sonja Riediger, Andreas Behrends, Björn Croll, Ignacio Vega-Naredo, Nils Hänig, Burkhard Poeggeler, Jutta Böker, Sascha Grube, Juliane Gipp, Ana Coto-Montes, Chandana Haldar, Rüdiger Hardeland. Toxicity of the quinalphos metabolite 2-hydroxyquinoxaline: growth inhibition, induction of oxidative stress, and genotoxicity in test organisms. Environmental toxicology. 2007 Feb; 22(1):33-43. doi: 10.1002/tox.20231. [PMID: 17295279]
  • Rüdiger Hardeland, S R Pandi-Perumal. Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug. Nutrition & metabolism. 2005 Sep; 2(?):22. doi: 10.1186/1743-7075-2-22. [PMID: 16153306]
  • Pramila Menon, Madhuban Gopal, Rajender Prasad. Influence of two insecticides, chlorpyrifos and quinalphos, on arginine ammonification and mineralizable nitrogen in two tropical soil types. Journal of agricultural and food chemistry. 2004 Dec; 52(24):7370-6. doi: 10.1021/jf049502c. [PMID: 15563221]