15-(4-Iodophenyl)pentadecanoic acid (BioDeep_00000172870)

   

human metabolite blood metabolite


代谢物信息卡片


Omega-(4-iodophenyl)pentadecanoic acid, 125I-labeled CPD

化学式: C21H33IO2 (444.1525188)
中文名称: 15-(4-碘苯基)十五酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1CCCCCCCCCCCCCCC(=O)O)I
InChI: InChI=1S/C21H33IO2/c22-20-17-15-19(16-18-20)13-11-9-7-5-3-1-2-4-6-8-10-12-14-21(23)24/h15-18H,1-14H2,(H,23,24)



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • C T Coburn, F F Knapp, M Febbraio, A L Beets, R L Silverstein, N A Abumrad. Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. The Journal of biological chemistry. 2000 Oct; 275(42):32523-9. doi: 10.1074/jbc.m003826200. [PMID: 10913136]
  • G W Sloof, F C Visser, E F Comans, J J Bax, T Teerlink, G J van der Vusse, F F Knapp. Metabolism of radioiodinated fatty acid analogs in ischemic and hypoxic canine myocardium. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1999 Jul; 40(7):1204-15. doi: ". [PMID: 10405143]
  • Y Ohmori, Y Imahori, S Ueda, R Fujii, K Wakita, M Inoue, S Tazawa. Radioiodinated diacylglycerol analogue: a potential imaging agent for single-photon emission tomographic investigations of cerebral ischaemia. European journal of nuclear medicine. 1996 Mar; 23(3):280-9. doi: 10.1007/bf00837626. [PMID: 8599959]
  • I C Dormehl, N Hugo, D Rossouw, A White, L E Feinendegen. Planar myocardial imaging in the baboon model with iodine-123-15-(iodophenyl)pentadecanoic acid (IPPA) and iodine-123-15-(P-iodophenyl)-3-R,S-methylpentadecanoic acid (BMIPP), using time-activity curves for evaluation of metabolism. Nuclear medicine and biology. 1995 Oct; 22(7):837-47. doi: 10.1016/0969-8051(95)00015-p. [PMID: 8547881]
  • L E Feinendegen, M M Henrich, J T Kuikka, K H Thompson, E G Vester, B Strauer. Myocardial lipid turnover in dilated cardiomyopathy: a dual in vivo tracer approach. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 1995 Jan; 2(1):42-52. doi: 10.1016/s1071-3581(05)80007-8. [PMID: 9420761]
  • G L Freeman, J T Colston, D D Miller. Alterations in myocardial free fatty acid clearance precede mechanical abnormalities in canine tachycardia-induced heart failure. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 1994 Mar; 1(2 Pt 1):171-9. doi: 10.1007/bf02984089. [PMID: 9420684]
  • I Dormehl, L Feinendegen, N Hugo, N Rossouw, A White. Comparative myocardial imaging in the baboon with 123I-labelled ortho and para isomers of 15-(iodophenyl)pentadecanoic acid (IPPA). Nuclear medicine communications. 1993 Nov; 14(11):998-1004. doi: 10.1097/00006231-199311000-00011. [PMID: 8290174]
  • M Eisenhut, W D Lehmann, A Sütterle. Metabolism of 15-(4'-[123I]iodophenyl)pentadecanoic acid ([123I]IPPA) in the rat heart; identification of new metabolites by high pressure liquid chromatography and fast atom bombardment-mass spectrometry. Nuclear medicine and biology. 1993 Aug; 20(6):747-54. doi: 10.1016/0969-8051(93)90161-m. [PMID: 8401375]
  • F F Knapp, J Kropp, D W McPherson, K R Ambrose, C R Lambert, A P Callahan, G Kirsch, H J Biersack. Site-specific/stable radioiodination of 1,2-Pal-3-IPPA: an agent for the potential clinical evaluation of pancreatic insufficiency by urine analysis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Jun; 34(6):946-52. doi: NULL. [PMID: 8509862]
  • G W Sloof, F C Visser, M J Eenige van, E F Comans, T Teerlink, J D Herscheid, G J Van der Vusse, F F Knapp. Comparison of uptake, oxidation and lipid distribution of 17-iodoheptadecanoic acid, 15-(p-iodophenyl)pentadecanoic acid and 15-(p-iodophenyl)-3,3-dimethylpentadecanoic acid in normal canine myocardium. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1993 Apr; 34(4):649-57. doi: ". [PMID: 8455083]
  • G W Sloof, F C Visser, T Teerlink, E F Comans, M J Eenige van, G J van der Vusse, F F Knapp. Incorporation of radioiodinated fatty acids into cardiac phospholipids of normoxic canine myocardium. Molecular and cellular biochemistry. 1992 Oct; 116(1-2):79-87. doi: 10.1007/bf01270573. [PMID: 1480157]
  • J Kropp, K R Ambrose, F F Knapp, H P Nissen, H J Biersack. Incorporation of radioiodinated IPPA and BMIPP fatty acid analogues into complex lipids from isolated rat hearts. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. 1992 Apr; 19(3):283-8. doi: 10.1016/0883-2897(92)90112-c. [PMID: 1629017]
  • K Vyska, W Meyer, W Stremmel, G Notohamiprodjo, K Minami, H J Machulla, U Gleichmann, H Meyer, R Körfer. Fatty acid uptake in normal human myocardium. Circulation research. 1991 Sep; 69(3):857-70. doi: 10.1161/01.res.69.3.857. [PMID: 1873878]
  • K P Kaiser, B Geuting, K Grossmann, E Vester, B Lösse, M A Antar, H J Machulla, L E Feinendegen. Tracer kinetics of 15-(ortho-123/131I-phenyl)-pentadecanoic acid (oPPA) and 15-(para-123/131I-phenyl)-pentadecanoic acid (pPPA) in animals and man. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1990 Oct; 31(10):1608-16. doi: ". [PMID: 2213181]
  • T R DeGrado, J E Holden, C K Ng, D M Raffel, S J Gatley. Quantitative analysis of myocardial kinetics of 15-p-[iodine-125] iodophenylpentadecanoic acid. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1989 Jul; 30(7):1211-8. doi: ". [PMID: 2738702]
  • K Vyska, H J Machulla, W Stremmel, D Fassbender, W H Knapp, G Notohamiprodjo, U Gleichmann, H Meyer, E J Knust, R Körfer. Regional myocardial free fatty acid extraction in normal and ischemic myocardium. Circulation. 1988 Nov; 78(5 Pt 1):1218-33. doi: 10.1161/01.cir.78.5.1218. [PMID: 3180379]
  • K R Ambrose, B A Owen, A P Callahan, M M Goodman, F F Knapp. Effects of fasting on the myocardial subcellular distribution and lipid distribution of terminal p-iodophenyl-substituted fatty acids in rats. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. 1988; 15(6):695-700. doi: 10.1016/0883-2897(88)90063-3. [PMID: 3251902]
  • K R Ambrose, B A Owen, M M Goodman, F F Knapp. Evaluation of the metabolism in rat hearts of two new radioiodinated 3-methyl-branched fatty acid myocardial imaging agents. European journal of nuclear medicine. 1987; 12(10):486-91. doi: 10.1007/bf00620471. [PMID: 3569336]
  • S N Reske, W Sauer, H J Machulla, J Knust, C Winkler. Metabolism of 15 (p 123I iodophenyl-)pentadecanoic acid in heart muscle and noncardiac tissues. European journal of nuclear medicine. 1985; 10(5-6):228-34. doi: 10.1007/bf00254466. [PMID: 3987699]
  • S N Reske, W Sauer, H J Machulla, C Winkler. 15(p-[123I]Iodophenyl)pentadecanoic acid as tracer of lipid metabolism: comparison with [1-14C]palmitic acid in murine tissues. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1984 Dec; 25(12):1335-42. doi: ". [PMID: 6334144]
  • B Schmitz, S N Reske, H J Machulla, H Egge, C Winkler. Cardiac metabolism of omega-(p-iodo-phenyl)-pentadecanoic acid: a gas-liquid chromatographic-mass spectrometric analysis. Journal of lipid research. 1984 Oct; 25(10):1102-8. doi: ". [PMID: 6512416]
  • M Ercan, R Senekowitsch, R Bauer, G Reidel, H Kriegel, H W Pabst. In vivo and in vitro studies with omega-[rho-123I-phenyl]-pentadecanoic acid in rats. The International journal of applied radiation and isotopes. 1983 Nov; 34(11):1519-24. doi: 10.1016/0020-708x(83)90286-7. [PMID: 6642711]
  • K R Chien, A Han, J White, P Kulkarni. In vivo esterification of a synthetic 125I-labeled fatty acid into cardiac glycerolipids. The American journal of physiology. 1983 Oct; 245(4):H693-7. doi: 10.1152/ajpheart.1983.245.4.h693. [PMID: 6624940]