[2,2'-Biquinoline]-4,4'-dicarboxylic acid (BioDeep_00000172709)
human metabolite blood metabolite
代谢物信息卡片
[2,2-Biquinoline]-4,4-dicarboxylic acid
化学式: C20H12N2O4 (344.07970320000004)
中文名称: 2,2＇-二喹啉-4,4＇-二羧酸
谱图信息:
最多检出来源 Homo sapiens(blood) 29.03%
分子结构信息
SMILES: C1=CC=C2C(=C1)C(=CC(=N2)C3=NC4=CC=CC=C4C(=C3)C(=O)O)C(=O)O
InChI: InChI=1S/C20H12N2O4/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18/h1-10H,(H,23,24)(H,25,26)
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sandeep Surendra Panikar, Gonzalo Ramírez-García, Siraj Sidhik, Tazara Lopez-Luke, Claramaria Rodriguez-Gonzalez, Inocencio Higuera Ciapara, Pedro Salas Castillo, Tanya Camacho-Villegas, Elder De la Rosa. Ultrasensitive SERS Substrate for Label-Free Therapeutic-Drug Monitoring of Paclitaxel and Cyclophosphamide in Blood Serum.
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PloS one.
2012; 7(2):e32222. doi:
10.1371/journal.pone.0032222. [PMID: 22384185] - Hongyu Liu, Ying Li, Yongwen Li, Baoxin Liu, Heng Wu, Jing Wang, Yuli Wang, Min Wang, Shou-Ching Tang, Qinghua Zhou, Jun Chen. Cloning and functional analysis of FLJ20420: a novel transcription factor for the BAG-1 promoter.
PloS one.
2012; 7(5):e34832. doi:
10.1371/journal.pone.0034832. [PMID: 22567091] - Rajesh Vasita, Dhirendra S Katti. Structural and functional characterization of proteins adsorbed on hydrophilized polylactide-co-glycolide microfibers.
International journal of nanomedicine.
2012; 7(?):61-71. doi:
10.2147/ijn.s26453. [PMID: 22275823] - Mahmoud M Suhail, Weijuan Wu, Amy Cao, Fadee G Mondalek, Kar-Ming Fung, Pin-Tsen Shih, Yu-Ting Fang, Cole Woolley, Gary Young, Hsueh-Kung Lin. Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells.
BMC complementary and alternative medicine.
2011 Dec; 11(?):129. doi:
10.1186/1472-6882-11-129. [PMID: 22171782] - Bao Lige, Julia D Romano, Veera Venkata Ratnam Bandaru, Karen Ehrenman, Jelena Levitskaya, Vera Sampels, Norman J Haughey, Isabelle Coppens. Deficiency of a Niemann-Pick, type C1-related protein in toxoplasma is associated with multiple lipidoses and increased pathogenicity.
PLoS pathogens.
2011 Dec; 7(12):e1002410. doi:
10.1371/journal.ppat.1002410. [PMID: 22174676] - Thomas W Cullen, David K Giles, Lindsey N Wolf, Chantal Ecobichon, Ivo G Boneca, M Stephen Trent. Helicobacter pylori versus the host: remodeling of the bacterial outer membrane is required for survival in the gastric mucosa.
PLoS pathogens.
2011 Dec; 7(12):e1002454. doi:
10.1371/journal.ppat.1002454. [PMID: 22216004] - Xiao-Fei Tian, Zhen Fang, Dan Jiang, Xi-Yan Sun. Pretreatment of microcrystalline cellulose in organic electrolyte solutions for enzymatic hydrolysis.
Biotechnology for biofuels.
2011 Nov; 4(1):53. doi:
10.1186/1754-6834-4-53. [PMID: 22099703] - Jing Ai, Qingjuan Tang, Yanlin Wu, Yang Xu, Teng Feng, Ruiyu Zhou, Yi Chen, Xin Gao, Qingfeng Zhu, Xihua Yue, Qiuming Pan, Siyun Xu, Jing Li, Min Huang, Jennifer Daugherty-Holtrop, Yuanzheng He, H Eric Xu, Jia Fan, Jian Ding, Meiyu Geng. The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma.
Journal of the National Cancer Institute.
2011 Nov; 103(22):1696-712. doi:
10.1093/jnci/djr360. [PMID: 22025622] - Gene A Morrill, Terry L Dowd, Adele B Kostellow, Raj K Gupta. Progesterone-induced changes in the phosphoryl potential during the meiotic divisions in amphibian oocytes: role of Na/K-ATPase.
BMC developmental biology.
2011 Nov; 11(?):67. doi:
10.1186/1471-213x-11-67. [PMID: 22054214] - Devapregasan Moodley, Girish M Mody, Anil A Chuturgoon. Initiation but no execution - modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis - a potential role for heat shock protein 70.
Journal of inflammation (London, England).
2011 Nov; 8(1):30. doi:
10.1186/1476-9255-8-30. [PMID: 22047640] - Jean-Luc Cacas, Anne-Sophie Petitot, Louis Bernier, Joan Estevan, Geneviève Conejero, Sébastien Mongrand, Diana Fernandez. Identification and characterization of the Non-race specific Disease Resistance 1 (NDR1) orthologous protein in coffee.
BMC plant biology.
2011 Oct; 11(?):144. doi:
10.1186/1471-2229-11-144. [PMID: 22023696] - Jaime L Lecker, Nirupa R Matthan, Jeffrey T Billheimer, Daniel J Rader, Alice H Lichtenstein. Changes in cholesterol homeostasis modify the response of F1B hamsters to dietary very long chain n-3 and n-6 polyunsaturated fatty acids.
Lipids in health and disease.
2011 Oct; 10(?):186. doi:
10.1186/1476-511x-10-186. [PMID: 22018327] - Sandeep Kumar Vashist, BinBin Zhang, Dan Zheng, Khalid Al-Rubeaan, John H T Luong, Fwu-Shan Sheu. Sulfo-N-hydroxysuccinimide interferes with bicinchoninic acid protein assay.
Analytical biochemistry.
2011 Oct; 417(1):156-8. doi:
10.1016/j.ab.2011.05.045. [PMID: 21704014] - Bianka Mussil, Ulrike Sauermann, Dirk Motzkus, Christiane Stahl-Hennig, Sieghart Sopper. Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys.
Retrovirology.
2011 Sep; 8(?):77. doi:
10.1186/1742-4690-8-77. [PMID: 21955401] - Timo Mühlhaus, Julia Weiss, Dorothea Hemme, Frederik Sommer, Michael Schroda. Quantitative shotgun proteomics using a uniform ¹⁵N-labeled standard to monitor proteome dynamics in time course experiments reveals new insights into the heat stress response of Chlamydomonas reinhardtii.
Molecular & cellular proteomics : MCP.
2011 Sep; 10(9):M110.004739. doi:
10.1074/mcp.m110.004739. [PMID: 21610104] - Fabienne C Fiesel, Christine Schurr, Stephanie S Weber, Philipp J Kahle. TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.
Molecular neurodegeneration.
2011 Aug; 6(?):64. doi:
10.1186/1750-1326-6-64. [PMID: 21878116] - Yassine Chtourou, Khaled Trabelsi, Hamadi Fetoui, Ghada Mkannez, Héla Kallel, Najiba Zeghal. Manganese induces oxidative stress, redox state unbalance and disrupts membrane bound ATPases on murine neuroblastoma cells in vitro: protective role of silymarin.
Neurochemical research.
2011 Aug; 36(8):1546-57. doi:
10.1007/s11064-011-0483-5. [PMID: 21533646] - Louiza Belkacemi, Andrea Jelks, Chun-Hung Chen, Michael G Ross, Mina Desai. Altered placental development in undernourished rats: role of maternal glucocorticoids.
Reproductive biology and endocrinology : RB&E.
2011 Aug; 9(?):105. doi:
10.1186/1477-7827-9-105. [PMID: 21806804] - Aliscia Daniels, Naeema Noor-Mahomed, Moganavelli Singh, M Ariatti. Cytofectin amine head group modification and degree of liposome pegylation: factors influencing gene transfer.
Indian journal of pharmaceutical sciences.
2011 Jul; 73(4):381-6. doi:
10.4103/0250-474x.95613. [PMID: 22707820] - Sergio González-Pérez, Jorge Gutiérrez, Francisco García-García, Daniel Osuna, Joaquín Dopazo, Óscar Lorenzo, José L Revuelta, Juan B Arellano. Early transcriptional defense responses in Arabidopsis cell suspension culture under high-light conditions.
Plant physiology.
2011 Jul; 156(3):1439-56. doi:
10.1104/pp.111.177766. [PMID: 21531897] - James D McCluskey, Dmytro Sava, Stephen C Harbison, Carlos A Muro-Cacho, Johnson T Giffe, Xu Ping, Raymond D Harbison. Hepatoprotective effects of select water-soluble PARP inhibitors in a carbon tetrachloride model.
International journal of critical illness and injury science.
2011 Jul; 1(2):97-103. doi:
10.4103/2229-5151.84788. [PMID: 22229131] - Montserrat Pinent, Andreas Prokesch, Hubert Hackl, Peter J Voshol, Ariane Klatzer, Evelyn Walenta, Ute Panzenboeck, Lukas Kenner, Zlatko Trajanoski, Gerald Hoefler, Juliane G Bogner-Strauss. Adipose triglyceride lipase and hormone-sensitive lipase are involved in fat loss in JunB-deficient mice.
Endocrinology.
2011 Jul; 152(7):2678-89. doi:
10.1210/en.2010-1477. [PMID: 21540289] - Clarisse S Muenyi, Vanessa A States, Joshua H Masters, Teresa W Fan, C William Helm, J Christopher States. Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC).
Journal of ovarian research.
2011 Jun; 4(?):9. doi:
10.1186/1757-2215-4-9. [PMID: 21696631] - Babu Raman, Catherine K McKeown, Miguel Rodriguez, Steven D Brown, Jonathan R Mielenz. Transcriptomic analysis of Clostridium thermocellum ATCC 27405 cellulose fermentation.
BMC microbiology.
2011 Jun; 11(?):134. doi:
10.1186/1471-2180-11-134. [PMID: 21672225] - Thomas F Gibbons, Stephen M Storey, Cecelia V Williams, Avery McIntosh, DeAnne M Mitchel, Rebecca D Parr, Megan E Schroeder, Friedhelm Schroeder, Judith M Ball. Rotavirus NSP4: Cell type-dependent transport kinetics to the exofacial plasma membrane and release from intact infected cells.
Virology journal.
2011 Jun; 8(?):278. doi:
10.1186/1743-422x-8-278. [PMID: 21645398] - Jacques Borg, Alex Campos, Claudio Diema, Núria Omeñaca, Eliandre de Oliveira, Joan Guinovart, Marta Vilaseca. Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns.
Clinical proteomics.
2011 Jun; 8(1):6. doi:
10.1186/1559-0275-8-6. [PMID: 21906361] - Amin A Momin, Hyejung Park, Brent J Portz, Christopher A Haynes, Rebecca L Shaner, Samuel L Kelly, I King Jordan, Jr Alfred H Merrill. A method for visualization of 'omic' datasets for sphingolipid metabolism to predict potentially interesting differences.
Journal of lipid research.
2011 Jun; 52(6):1073-1083. doi:
10.1194/jlr.m010454. [PMID: 21415121] - Nao Inoue, Koji Nagao, Kotaro Sakata, Naomi Yamano, Pathma Elgoda Ranawakage Gunawardena, Seo-Young Han, Toshiro Matsui, Toshihiro Nakamori, Hitoshi Furuta, Kiyoharu Takamatsu, Teruyoshi Yanagita. Screening of soy protein-derived hypotriglyceridemic di-peptides in vitro and in vivo.
Lipids in health and disease.
2011 May; 10(?):85. doi:
10.1186/1476-511x-10-85. [PMID: 21600040] - Robyn M Carey, Jan K Blusztajn, Barbara E Slack. Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin.
BMC cell biology.
2011 May; 12(?):20. doi:
10.1186/1471-2121-12-20. [PMID: 21586144] - Guozhu Chen, Xuhui Zhang, Ming Zhao, Yan Wang, Xiang Cheng, Di Wang, Yuanji Xu, Zhiyan Du, Xiaodan Yu. Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells.
BMC cancer.
2011 May; 11(?):170. doi:
10.1186/1471-2407-11-170. [PMID: 21569548] - Yan Lu, David A Hall, Robert L Last. A small zinc finger thylakoid protein plays a role in maintenance of photosystem II in Arabidopsis thaliana.
The Plant cell.
2011 May; 23(5):1861-75. doi:
10.1105/tpc.111.085456. [PMID: 21586683] - Gabriella Rimkus, Sibylle Bremer-Streck, Cordula Grüttner, Werner Alois Kaiser, Ingrid Hilger. Can we accurately quantify nanoparticle associated proteins when constructing high-affinity MRI molecular imaging probes?.
Contrast media & molecular imaging.
2011 May; 6(3):119-25. doi:
10.1002/cmmi.405. [PMID: 21698770] - Yoshinori Utsumi, Chikako Utsumi, Takayuki Sawada, Naoko Fujita, Yasunori Nakamura. Functional diversity of isoamylase oligomers: the ISA1 homo-oligomer is essential for amylopectin biosynthesis in rice endosperm.
Plant physiology.
2011 May; 156(1):61-77. doi:
10.1104/pp.111.173435. [PMID: 21436381] - Rachana Shah, Christine C Hinkle, Jane F Ferguson, Nehal N Mehta, Mingyao Li, Liming Qu, Yun Lu, Mary E Putt, Rexford S Ahima, Muredach P Reilly. Fractalkine is a novel human adipochemokine associated with type 2 diabetes.
Diabetes.
2011 May; 60(5):1512-8. doi:
10.2337/db10-0956. [PMID: 21525510]