12-Hydroxyheptadeca-5,8,10-trienoic acid (BioDeep_00000172682)

Main id: BioDeep_00000004028

 

human metabolite blood metabolite


代谢物信息卡片


12-Hydroxy-5,8,10-heptadecatrienoic acid, (S)-(Z,e,e)-isomer

化学式: C17H28O3 (280.2038)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(not specific) 50%

分子结构信息

SMILES: CCCCCC(O)C=CC=CCC=CCCCC(O)=O
InChI: InChI=1S/C17H28O3/c1-2-3-10-13-16(18)14-11-8-6-4-5-7-9-12-15-17(19)20/h5-8,11,14,16,18H,2-4,9-10,12-13,15H2,1H3,(H,19,20)

描述信息

同义名列表

9 个代谢物同义名

12-Hydroxy-5,8,10-heptadecatrienoic acid, (S)-(Z,e,e)-isomer; 12-Hydroxy-5,8,10-heptadecatrienoic acid, (S)-(e,Z,Z)-isomer; 12-Hydroxy-5,8,10-heptadecatrienoic acid, (e,Z,Z)-isomer; 12-Hydroxy-5,8,10-heptadecatrienoic acid, (S)-isomer; 12-L-Hydroxy-5,8,10-heptadecatrienoic acid; 12-hydroxy-5,8,10-heptadecatrienoic acid; 12-hydroxyheptadeca-5,8,10-trienoic acid; 12-Hydroxyheptadeca-5,8,10-trienoate; Hydroxyheptadecatrienoic acid



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Si-Yang Fan, Hua-Wu Zeng, Yue-Hu Pei, Li Li, Ji Ye, Yue-Xin Pan, Ji-Gang Zhang, Xing Yuan, Wei-Dong Zhang. The anti-inflammatory activities of an extract and compounds isolated from Platycladus orientalis (Linnaeus) Franco in vitro and ex vivo. Journal of ethnopharmacology. 2012 Jun; 141(2):647-52. doi: 10.1016/j.jep.2011.05.019. [PMID: 21619922]
  • Undurti N Das, N Madhavi. Effect of polyunsaturated fatty acids on drug-sensitive and resistant tumor cells in vitro. Lipids in health and disease. 2011 Sep; 10(?):159. doi: 10.1186/1476-511x-10-159. [PMID: 21917129]
  • Huawu Zeng, Shengshan Dou, Jing Zhao, Siyang Fan, Xing Yuan, Shuanglai Zhu, Li Li, Weidong Zhang, Runhui Liu. The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. Journal of ethnopharmacology. 2011 May; 135(2):561-8. doi: 10.1016/j.jep.2011.03.055. [PMID: 21466840]
  • C E Espada, M A Berra, M J Martinez, A R Eynard, M E Pasqualini. Effect of Chia oil (Salvia Hispanica) rich in omega-3 fatty acids on the eicosanoid release, apoptosis and T-lymphocyte tumor infiltration in a murine mammary gland adenocarcinoma. Prostaglandins, leukotrienes, and essential fatty acids. 2007 Jul; 77(1):21-8. doi: 10.1016/j.plefa.2007.05.005. [PMID: 17618100]
  • Petra Frohberg, Guntram Drutkowski, Ivonne Wobst. Monitoring eicosanoid biosynthesis via lipoxygenase and cyclooxygenase pathways in human whole blood by single HPLC run. Journal of pharmaceutical and biomedical analysis. 2006 Jun; 41(4):1317-24. doi: 10.1016/j.jpba.2006.02.046. [PMID: 16621414]
  • Ingrid Beck-Speier, Niru Dayal, Claudio Denzlinger, Christopher Haberl, Konrad L Maier, Axel Ziesenis, Joachim Heyder. Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. Prostaglandins & other lipid mediators. 2003 Jul; 71(3-4):217-34. doi: 10.1016/s1098-8823(03)00041-8. [PMID: 14518563]
  • Ana M Vecino, José L Teruel, José L Navarro, Jesús M Cesar. Phospholipase A2 activity in platelets of patients with uremia. Platelets. 2002 Nov; 13(7):415-8. doi: 10.1080/0953710021000024000. [PMID: 12487789]
  • I Beck-Speier, N Dayal, E Karg, K L Maier, C Roth, A Ziesenis, J Heyder. Agglomerates of ultrafine particles of elemental carbon and TiO2 induce generation of lipid mediators in alveolar macrophages. Environmental health perspectives. 2001 Aug; 109 Suppl 4(?):613-8. doi: 10.1289/ehp.01109s4613. [PMID: 11544173]
  • Z Avnur, I Nathan, A Dvilansky, A Livne. Plasma constituent (s) inhibiting platelet adhesiveness. Israel journal of medical sciences. 1977 Mar; 13(3):264-71. doi: NULL. [PMID: 15956]
  • A Brock. Binding of digitoxin to human serum albumin: influence of ionic strength and ionic medium on the digitoxin-albumin complex formation. Acta pharmacologica et toxicologica. 1975 Nov; 37(5):361-8. doi: 10.1111/j.1600-0773.1975.tb00854.x. [PMID: 887]