BCECF-acetoxymethyl (BioDeep_00000172659)
human metabolite blood metabolite
代谢物信息卡片
化学式: C42H40O21 (880.2062)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 83.33%
分子结构信息
SMILES: CC(=O)OCOC(=O)CCC1=C(OCOC(C)=O)C=C2OC3=CC(OCOC(C)=O)=C(CCC(=O)OCOC(C)=O)C=C3C3(OC(=O)C4=C3C=CC(=C4)C(=O)OCOC(C)=O)C2=C1
InChI: InChI=1S/C42H40O21/c1-22(43)52-17-57-34-15-36-32(13-27(34)7-10-38(48)59-19-54-24(3)45)42(31-9-6-29(12-30(31)41(51)63-42)40(50)61-21-56-26(5)47)33-14-28(8-11-39(49)60-20-55-25(4)46)35(16-37(33)62-36)58-18-53-23(2)44/h6,9,12-16H,7-8,10-11,17-21H2,1-5H3
描述信息
D004396 - Coloring Agents > D005456 - Fluorescent Dyes > D005452 - Fluoresceins
同义名列表
7 个代谢物同义名
(acetyloxy)methyl 3-{3,6-bis[(acetyloxy)methoxy]-7-{3-[(acetyloxy)methoxy]-3-oxopropyl}-5-{[(acetyloxy)methoxy]carbonyl}-3-oxo-3H-spiro[2-benzofuran-1,9-xanthene]-2-yl}propanoate; (acetyloxy)methyl 3-{3,6-bis[(acetyloxy)methoxy]-7-{3-[(acetyloxy)methoxy]-3-oxopropyl}-5-{[(acetyloxy)methoxy]carbonyl}-3-oxospiro[2-benzofuran-1,9-xanthene]-2-yl}propanoate; 2,7-Bis-(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester; Bis(carboxyethyl)carboxyfluorescein acetoxymethyl ester; BCECF-acetoxymethyl; BCECF-AM; 2,7-CCAE
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Wen Liu, Núria M Pastor-Soler, Carlos Schreck, Beth Zavilowitz, Thomas R Kleyman, Lisa M Satlin. Luminal flow modulates H+-ATPase activity in the cortical collecting duct (CCD).
American journal of physiology. Renal physiology.
2012 Jan; 302(1):F205-15. doi:
10.1152/ajprenal.00179.2011. [PMID: 21957178] - Karina Thieme, Débora Mai N Eguti, Margarida Mello-Aires, Maria Oliveira-Souza. The effect of angiotensin II on intracellular pH is mediated by AT(1) receptor translocation.
American journal of physiology. Cell physiology.
2008 Jul; 295(1):C138-45. doi:
10.1152/ajpcell.00512.2007. [PMID: 18434621] - Carmen Vale-González, Belén Gómez-Limia, Mercedes R Vieytes, Luis M Botana. Effects of the marine phycotoxin palytoxin on neuronal pH in primary cultures of cerebellar granule cells.
Journal of neuroscience research.
2007 Jan; 85(1):90-8. doi:
10.1002/jnr.21095. [PMID: 17075922] - Carmen Vale-González, Amparo Alfonso, Cristina Suñol, Mercedes R Vieytes, Luis M Botana. Role of the plasma membrane calcium adenosine triphosphatase on domoate-induced intracellular acidification in primary cultures of cerebelar granule cells.
Journal of neuroscience research.
2006 Aug; 84(2):326-37. doi:
10.1002/jnr.20878. [PMID: 16634067] - P F Speake, K J Mynett, J D Glazier, S L Greenwood, C P Sibley. Activity and expression of Na+/H+ exchanger isoforms in the syncytiotrophoblast of the human placenta.
Pflugers Archiv : European journal of physiology.
2005 May; 450(2):123-30. doi:
10.1007/s00424-005-1382-x. [PMID: 15772858] - Jennifer L Bankers-Fulbright, Gail M Kephart, Kathleen R Bartemes, Hirohito Kita, Scott M O'Grady. Platelet-activating factor stimulates cytoplasmic alkalinization and granule acidification in human eosinophils.
Journal of cell science.
2004 Nov; 117(Pt 24):5749-57. doi:
10.1242/jcs.01498. [PMID: 15507482] - Gary Sweeney, Rami R Garg, Rolando B Ceddia, Dailin Li, Manabu Ishiki, Romel Somwar, Leonard J Foster, Paul O Neilsen, Glenn D Prestwich, Assaf Rudich, Amira Klip. Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake.
The Journal of biological chemistry.
2004 Jul; 279(31):32233-42. doi:
10.1074/jbc.m402897200. [PMID: 15166230] - Virginie Aires, Aziz Hichami, Kabirou Moutairou, Naim Akhtar Khan. Docosahexaenoic acid and other fatty acids induce a decrease in pHi in Jurkat T-cells.
British journal of pharmacology.
2003 Dec; 140(7):1217-26. doi:
10.1038/sj.bjp.0705563. [PMID: 14645139] - M Hershfinkel, A Moran, N Grossman, I Sekler. A zinc-sensing receptor triggers the release of intracellular Ca2+ and regulates ion transport.
Proceedings of the National Academy of Sciences of the United States of America.
2001 Sep; 98(20):11749-54. doi:
10.1073/pnas.201193398. [PMID: 11573009] - M M Kneen, D G Harkin, L L Walker, D Alcorn, P J Harris. Imaging of renal medullary interstitial cells in situ by confocal fluorescence microscopy.
Anatomy and embryology.
1999 Jul; 200(1):117-21. doi:
10.1007/s004290050265. [PMID: 10395012] - D W Johnson, B K Brew, P Poronnik, D I Cook, M J Field, A Z Györy, C A Pollock. Insulin-like growth factor I stimulates apical sodium/hydrogen exchange in human proximal tubule cells.
The American journal of physiology.
1997 Apr; 272(4 Pt 2):F484-90. doi:
10.1152/ajprenal.1997.272.4.f484. [PMID: 9140049] - N J Raat, P De Smet, W van Driessche, R J Bindels, C H Van Os. Measuring volume perturbation of proximal tubular cells in primary culture with three different techniques.
The American journal of physiology.
1996 Jul; 271(1 Pt 1):C235-41. doi:
10.1152/ajpcell.1996.271.1.c235. [PMID: 8760051] - E M Denholm, G P Stankus. Differential effects of two fluorescent probes on macrophage migration as assessed by manual and automated methods.
Cytometry.
1995 Apr; 19(4):366-9. doi:
10.1002/cyto.990190412. [PMID: 7796702] - L Jiang, A Stuart-Tilley, J Parkash, S L Alper. pHi and serum regulate AE2-mediated Cl-/HCO3- exchange in CHOP cells of defined transient transfection status.
The American journal of physiology.
1994 Sep; 267(3 Pt 1):C845-56. doi:
10.1152/ajpcell.1994.267.3.c845. [PMID: 7524338] - R Lichtenfels, W E Biddison, H Schulz, A B Vogt, R Martin. CARE-LASS (calcein-release-assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity.
Journal of immunological methods.
1994 Jun; 172(2):227-39. doi:
10.1016/0022-1759(94)90110-4. [PMID: 7518485] - A R Karuri, E Dobrowsky, I F Tannock. Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment.
British journal of cancer.
1993 Dec; 68(6):1080-7. doi:
10.1038/bjc.1993.485. [PMID: 8260358] - I D Weiner, C S Wingo, L L Hamm. Regulation of intracellular pH in two cell populations of inner stripe of rabbit outer medullary collecting duct.
The American journal of physiology.
1993 Sep; 265(3 Pt 2):F406-15. doi:
10.1152/ajprenal.1993.265.3.f406. [PMID: 8214100] - R S Haworth, L Fliegel. Intracellular pH in Schizosaccharomyces pombe--comparison with Saccharomyces cerevisiae.
Molecular and cellular biochemistry.
1993 Jul; 124(2):131-40. doi:
10.1007/bf00929205. [PMID: 8232284] - R S Haworth, B D Lemire, D Crandall, E J Cragoe, L Fliegel. Characterisation of proton fluxes across the cytoplasmic membrane of the yeast Saccharomyces cerevisiae.
Biochimica et biophysica acta.
1991 Dec; 1098(1):79-89. doi:
10.1016/0005-2728(91)90011-c. [PMID: 1661160] - L S Kao, M Y Ho, E J Cragoe. Intracellular pH and catecholamine secretion from bovine adrenal chromaffin cells.
Journal of neurochemistry.
1991 Nov; 57(5):1656-60. doi:
10.1111/j.1471-4159.1991.tb06365.x. [PMID: 1919580] - W S Marshall, S E Bryson. Intracellular pH regulation in trout urinary bladder epithelium: Na(+)-H+(NH4+) exchange.
The American journal of physiology.
1991 Sep; 261(3 Pt 2):R652-8. doi:
10.1152/ajpregu.1991.261.3.r652. [PMID: 1653543] - R L Lubman, S I Danto, E D Crandall. Evidence for active H+ secretion by rat alveolar epithelial cells.
The American journal of physiology.
1989 Dec; 257(6 Pt 1):L438-45. doi:
10.1152/ajplung.1989.257.6.l438. [PMID: 2610271] - J Noël, A Tejedor, P Vinay, R Laprade. Fluorescence measurement of intracellular pH on proximal tubule suspensions. The need for a BCECF sink.
Renal physiology and biochemistry.
1989 Sep; 12(5-6):371-87. doi:
10.1159/000173215. [PMID: 2623351] - A Ogawa, Y Ishikawa, S Sasakawa. Effects of changes in intracellular pH induced by platelet storage and treatment with monovalent cation ionophores on platelet functions.
Thrombosis research.
1988 Dec; 52(5):369-79. doi:
10.1016/0049-3848(88)90021-7. [PMID: 3222781]
