11-Ketotestosterone (BioDeep_00000172605)

   

human metabolite blood metabolite


代谢物信息卡片


17-hydroxy-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione

化学式: C19H26O3 (302.1881846)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 92.86%

分子结构信息

SMILES: CC12CC(=O)C3C(CCC4=CC(=O)CCC34C)C1CCC2O
InChI: InChI=1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-14,16-17,22H,3-8,10H2,1-2H3



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Kohei Ohta, Mami Sakai, Jittendra Kumar Sundaray, Takeshi Kitano, Tatsusuke Takeda, Akihiko Yamaguchi, Michiya Matsuyama. Bidirectional sex change induced by sex steroid implantation in the hermaphrodite fish, Pseudolabrus sieboldi. Journal of experimental zoology. Part A, Ecological genetics and physiology. 2012 Nov; 317(9):552-60. doi: 10.1002/jez.1747. [PMID: 22927221]
  • Achim Trubiroha, Hana Kroupova, Sven Wuertz, Werner Kloas. Up-regulation of gonadotropin mRNA-expression at the onset of gametogenesis in the roach (Rutilus rutilus): evidence for an important role of brain-type aromatase (cyp19a1b) in the pituitary. General and comparative endocrinology. 2012 Sep; 178(3):529-38. doi: 10.1016/j.ygcen.2012.07.002. [PMID: 22814335]
  • Rachel M Genova, Margaret A Marchaterre, Rosemary Knapp, Daniel Fergus, Andrew H Bass. Glucocorticoid and androgen signaling pathways diverge between advertisement calling and non-calling fish. Hormones and behavior. 2012 Sep; 62(4):426-32. doi: 10.1016/j.yhbeh.2012.07.010. [PMID: 22884426]
  • Alejandro S Mechaly, Jordi Viñas, Francesc Piferrer. Sex-specific changes in the expression of kisspeptin, kisspeptin receptor, gonadotropins and gonadotropin receptors in the Senegalese sole (Solea senegalensis) during a full reproductive cycle. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2012 Aug; 162(4):364-71. doi: 10.1016/j.cbpa.2012.04.003. [PMID: 22537879]
  • Felipe Alonso, Renato Massaaki Honji, Renata Guimarães Moreira, Matías Pandolfi. Dominance hierarchies and social status ascent opportunity: anticipatory behavioral and physiological adjustments in a Neotropical cichlid fish. Physiology & behavior. 2012 Jul; 106(5):612-8. doi: 10.1016/j.physbeh.2012.04.003. [PMID: 22521514]
  • Richard J Kavanagh, Richard A Frank, B Kent Burnison, Rozlyn F Young, Phillip M Fedorak, Keith R Solomon, Glen Van Der Kraak. Fathead minnow (Pimephales promelas) reproduction is impaired when exposed to a naphthenic acid extract. Aquatic toxicology (Amsterdam, Netherlands). 2012 Jul; 116-117(?):34-42. doi: 10.1016/j.aquatox.2012.03.002. [PMID: 22459411]
  • Xiaoshan Liu, Kyunghee Ji, Kyungho Choi. Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 2012 Jun; 114-115(?):173-81. doi: 10.1016/j.aquatox.2012.02.019. [PMID: 22446829]
  • Alvin N Setiawan, Yuichi Ozaki, Alireza Shoae, Yukinori Kazeto, P Mark Lokman. Androgen-specific regulation of FSH signalling in the previtellogenic ovary and pituitary of the New Zealand shortfinned eel, Anguilla australis. General and comparative endocrinology. 2012 Apr; 176(2):132-43. doi: 10.1016/j.ygcen.2011.12.041. [PMID: 22343137]
  • Ryusuke Sudo, Ryota Tosaka, Shigeho Ijiri, Shinji Adachi, Jun Aoyama, Katsumi Tsukamoto. 11-ketotestosterone synchronously induces oocyte development and silvering-related changes in the Japanese eel, Anguilla japonica. Zoological science. 2012 Apr; 29(4):254-9. doi: 10.2108/zsj.29.254. [PMID: 22468835]
  • Erik Hoffmann, Anders Walstad, Johnny Karlsson, Per-Erik Olsson, Bertil Borg. Androgen receptor-beta mRNA levels in different tissues in breeding and post-breeding male and female sticklebacks, Gasterosteus aculeatus. Reproductive biology and endocrinology : RB&E. 2012 Mar; 10(?):23. doi: 10.1186/1477-7827-10-23. [PMID: 22455382]
  • Amy L Filby, Gregory C Paull, Faye Searle, Maren Ortiz-Zarragoitia, Charles R Tyler. Environmental estrogen-induced alterations of male aggression and dominance hierarchies in fish: a mechanistic analysis. Environmental science & technology. 2012 Mar; 46(6):3472-9. doi: 10.1021/es204023d. [PMID: 22360147]
  • R Schiavone, L Zilli, C Storelli, S Vilella. Changes in hormonal profile, gonads and sperm quality of Argyrosomus regius (Pisces, Scianidae) during the first sexual differentiation and maturation. Theriogenology. 2012 Mar; 77(5):888-98. doi: 10.1016/j.theriogenology.2011.09.014. [PMID: 22153261]
  • Christopher Sauvage, Marie Vagner, Nicolas Derôme, Céline Audet, Louis Bernatchez. Coding Gene Single Nucleotide Polymorphism Mapping and Quantitative Trait Loci Detection for Physiological Reproductive Traits in Brook Charr, Salvelinus fontinalis. G3 (Bethesda, Md.). 2012 Mar; 2(3):379-92. doi: 10.1534/g3.111.001867. [PMID: 22413092]
  • Reynaldo Patiño, Michael R Rosen, Erik L Orsak, Steven L Goodbred, Thomas W May, David Alvarez, Kathy R Echols, Carla M Wieser, Shane Ruessler, Leticia Torres. Patterns of metal composition and biological condition and their association in male common carp across an environmental contaminant gradient in Lake Mead National Recreation Area, Nevada and Arizona, USA. The Science of the total environment. 2012 Feb; 416(?):215-24. doi: 10.1016/j.scitotenv.2011.11.082. [PMID: 22206697]
  • Saman Athauda, Trevor Anderson, Rocky de Nys. Effect of rearing water temperature on protandrous sex inversion in cultured Asian Seabass (Lates calcarifer). General and comparative endocrinology. 2012 Feb; 175(3):416-23. doi: 10.1016/j.ygcen.2011.11.040. [PMID: 22155035]
  • Ian A E Butts, Oliver P Love, Michelle Farwell, Trevor E Pitcher. Primary and secondary sexual characters in alternative reproductive tactics of Chinook salmon: Associations with androgens and the maturation-inducing steroid. General and comparative endocrinology. 2012 Feb; 175(3):449-56. doi: 10.1016/j.ygcen.2011.11.041. [PMID: 22172341]
  • Frank Pfennig, Thomas Kurth, Stefan Meissner, Andrea Standke, Markus Hoppe, Freia Zieschang, Christine Reitmayer, Andy Göbel, Georg Kretzschmar, Herwig O Gutzeit. The social status of the male Nile tilapia (Oreochromis niloticus) influences testis structure and gene expression. Reproduction (Cambridge, England). 2012 Jan; 143(1):71-84. doi: 10.1530/rep-11-0292. [PMID: 22031714]
  • H Rosenfeld, C C Mylonas, C R Bridges, G Heinisch, A Corriero, R Vassallo-Aguis, A Medina, A Belmonte, A Garcia, F De la Gándara, C Fauvel, G De Metrio, I Meiri-Ashkenazi, H Gordin, Y Zohar. GnRHa-mediated stimulation of the reproductive endocrine axis in captive Atlantic bluefin tuna, Thunnus thynnus. General and comparative endocrinology. 2012 Jan; 175(1):55-64. doi: 10.1016/j.ygcen.2011.09.013. [PMID: 22015989]
  • Yukinori Kazeto, Ryota Tosaka, Hajime Matsubara, Shigeho Ijiri, Shinji Adachi. Ovarian steroidogenesis and the role of sex steroid hormones on ovarian growth and maturation of the Japanese eel. The Journal of steroid biochemistry and molecular biology. 2011 Nov; 127(3-5):149-54. doi: 10.1016/j.jsbmb.2011.03.013. [PMID: 21414407]
  • Perrine Geraudie, Nathalie Hinfray, Marie Gerbron, Jean-Marc Porcher, François Brion, Christophe Minier. Brain cytochrome P450 aromatase activity in roach (Rutilus rutilus): seasonal variations and impact of environmental contaminants. Aquatic toxicology (Amsterdam, Netherlands). 2011 Oct; 105(3-4):378-84. doi: 10.1016/j.aquatox.2011.07.009. [PMID: 21820384]
  • V Macnab, A P Scott, I Katsiadaki, I Barber. Variation in the reproductive potential of Schistocephalus infected male sticklebacks is associated with 11-ketotestosterone titre. Hormones and behavior. 2011 Sep; 60(4):371-9. doi: 10.1016/j.yhbeh.2011.07.005. [PMID: 21781969]
  • P Poncin, B Nzau Matondo, C Termol, P Kestemont, J C Philippart. Relationships between circulating androgens, aggressive behaviour and breeding tubercles in males of the common bream Abramis brama L. in an aquarium environment. Fish physiology and biochemistry. 2011 Sep; 37(3):533-42. doi: 10.1007/s10695-010-9455-y. [PMID: 21132526]
  • Yohana M Velasco-Santamaría, Bodil Korsgaard, Steffen S Madsen, Poul Bjerregaard. Bezafibrate, a lipid-lowering pharmaceutical, as a potential endocrine disruptor in male zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 2011 Sep; 105(1-2):107-18. doi: 10.1016/j.aquatox.2011.05.018. [PMID: 21703979]
  • Xuesong Hu, Xiaochun Liu, Haifa Zhang, Yong Zhang, Shuisheng Li, Qing Sang, Qian Wang, Wenna Luo, Qizhi Liu, Danqi Lu, Zining Meng, Haoran Lin. Expression profiles of gonadotropins and their receptors during 17α-methyltestosterone implantation-induced sex change in the orange-spotted grouper (Epinephelus coioides). Molecular reproduction and development. 2011 Jun; 78(6):376-90. doi: 10.1002/mrd.21319. [PMID: 21567650]
  • Arjan P Palstra, Ma Angeles Guerrero, Gerard de Laak, Jan P G Klein Breteler, Guido E E J M van den Thillart. Temporal progression in migratory status and sexual maturation in European silver eels during downstream migration. Fish physiology and biochemistry. 2011 Jun; 37(2):285-96. doi: 10.1007/s10695-011-9496-x. [PMID: 21556699]
  • Efthimia Antonopoulou, Athanassios C Tsikliras, Martin Kocour, Vladimir Zlábek, Martin Flajšhans, David Gela, Veronika Piačková, Alexander P Scott. Teleost maturation-inducing hormone, 17,20β-dihydroxypregn-4-en-3-one, peaks after spawning in Tinca tinca. General and comparative endocrinology. 2011 Jun; 172(2):234-42. doi: 10.1016/j.ygcen.2011.03.008. [PMID: 21420410]
  • Katherine A A Aoki, Catherine A Harris, Ioanna Katsiadaki, John P Sumpter. Evidence suggesting that di-n-butyl phthalate has antiandrogenic effects in fish. Environmental toxicology and chemistry. 2011 Jun; 30(6):1338-45. doi: 10.1002/etc.502. [PMID: 21337613]
  • Rubén Marín-Juez, Barbara Castellana, Manuel Manchado, Josep V Planas. Molecular identification of genes involved in testicular steroid synthesis and characterization of the response to gonadotropic stimulation in the Senegalese sole (Solea senegalensis) testis. General and comparative endocrinology. 2011 May; 172(1):130-9. doi: 10.1016/j.ygcen.2011.02.003. [PMID: 21310154]
  • A Ross Brown, Lisa K Bickley, Gareth Le Page, David John Hosken, Gregory C Paull, Patrick B Hamilton, Stewart F Owen, Joanna Robinson, Alan D Sharpe, Charles R Tyler. Are toxicological responses in laboratory (inbred) zebrafish representative of those in outbred (wild) populations? - A case study with an endocrine disrupting chemical. Environmental science & technology. 2011 May; 45(9):4166-72. doi: 10.1021/es200122r. [PMID: 21469706]
  • Luigi Margiotta-Casaluci, John P Sumpter. 5α-Dihydrotestosterone is a potent androgen in the fathead minnow (Pimephales promelas). General and comparative endocrinology. 2011 May; 171(3):309-18. doi: 10.1016/j.ygcen.2011.02.012. [PMID: 21354156]
  • Andrew D Southam, Anke Lange, Adam Hines, Elizabeth M Hill, Yoshinao Katsu, Taisen Iguchi, Charles R Tyler, Mark R Viant. Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): implications for biomonitoring. Environmental science & technology. 2011 Apr; 45(8):3759-67. doi: 10.1021/es103814d. [PMID: 21410251]
  • Taku Endo, Takashi Todo, P Mark Lokman, Hideaki Kudo, Shigeho Ijiri, Shinji Adachi, Kohei Yamauchi. Androgens and very low density lipoprotein are essential for the growth of previtellogenic oocytes from Japanese eel, Anguilla japonica, in vitro. Biology of reproduction. 2011 Apr; 84(4):816-25. doi: 10.1095/biolreprod.110.087163. [PMID: 21148104]
  • Louise M Stevenson, Alexandria C Brown, Tracy M Montgomery, Ethan D Clotfelter. Reproductive consequences of exposure to waterborne phytoestrogens in male fighting fish Betta splendens. Archives of environmental contamination and toxicology. 2011 Apr; 60(3):501-10. doi: 10.1007/s00244-010-9561-y. [PMID: 20589370]
  • D Hala, M D Overturf, L H Petersen, D B Huggett. Quantification of 2-hydrazinopyridine derivatized steroid hormones in fathead minnow (Pimephales promelas) blood plasma using LC-ESI+/MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Mar; 879(9-10):591-8. doi: 10.1016/j.jchromb.2011.01.020. [PMID: 21317049]
  • Yogesh Kumar Katare, Alexander P Scott, Alyson J Laframboise, Weiming Li, Zena Alyasha'e, Christopher B Caputo, Stephen J Loeb, Barbara Zielinski. Release of free and conjugated forms of the putative pheromonal steroid 11-oxo-etiocholanolone by reproductively mature male round goby (Neogobius melanostomus Pallas, 1814). Biology of reproduction. 2011 Feb; 84(2):288-98. doi: 10.1095/biolreprod.110.086546. [PMID: 20944082]
  • José M Guzmán, Rosa Cal, Angel García-López, Olvido Chereguini, Katherine Kight, Mercedes Olmedo, Carmen Sarasquete, Constantinos C Mylonas, José B Peleteiro, Yonathan Zohar, Evaristo L Mañanós. Effects of in vivo treatment with the dopamine antagonist pimozide and gonadotropin-releasing hormone agonist (GnRHa) on the reproductive axis of Senegalese sole (Solea senegalensis). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2011 Feb; 158(2):235-45. doi: 10.1016/j.cbpa.2010.11.016. [PMID: 21112410]
  • E Espinosa, A Josa, L Gil, N González. Sex steroid levels in XY males and sex-reversed XX males, of rainbow trout (Oncorhynchus mykiss), during the reproductive cycle. Reproduction in domestic animals = Zuchthygiene. 2011 Feb; 46(1):8-14. doi: 10.1111/j.1439-0531.2009.01512.x. [PMID: 19663812]
  • Bonnie Gemmill, Kerri Pleskach, Lisa Peters, Vince Palace, Kerry Wautier, Brad Park, Colin Darling, Bruno Rosenberg, Robert McCrindle, Gregg T Tomy. Toxicokinetics of tetrabromoethylcyclohexane (TBECH) in juvenile brown trout (Salmo trutta) and effects on plasma sex hormones. Aquatic toxicology (Amsterdam, Netherlands). 2011 Jan; 101(2):309-17. doi: 10.1016/j.aquatox.2010.11.003. [PMID: 21216340]
  • Richard J Kavanagh, Richard A Frank, Ken D Oakes, Mark R Servos, Rozlyn F Young, Phillip M Fedorak, Mike D MacKinnon, Keith R Solomon, D George Dixon, Glen Van Der Kraak. Fathead minnow (Pimephales promelas) reproduction is impaired in aged oil sands process-affected waters. Aquatic toxicology (Amsterdam, Netherlands). 2011 Jan; 101(1):214-20. doi: 10.1016/j.aquatox.2010.09.021. [PMID: 20980067]
  • Meghan L M Fuzzen, Nicholas J Bernier, Glen Van Der Kraak. Differential effects of 17β-estradiol and 11-ketotestosterone on the endocrine stress response in zebrafish (Danio rerio). General and comparative endocrinology. 2011 Jan; 170(2):365-73. doi: 10.1016/j.ygcen.2010.10.014. [PMID: 20977907]
  • E Cabrita, F Soares, J Beirão, A García-López, G Martínez-Rodríguez, M T Dinis. Endocrine and milt response of Senegalese sole, Solea senegalensis, males maintained in captivity. Theriogenology. 2011 Jan; 75(1):1-9. doi: 10.1016/j.theriogenology.2010.07.003. [PMID: 20833416]
  • Chun-Chun Chen, Russell D Fernald. Visual information alone changes behavior and physiology during social interactions in a cichlid fish (Astatotilapia burtoni). PloS one. 2011; 6(5):e20313. doi: 10.1371/journal.pone.0020313. [PMID: 21633515]
  • Yasuhisa Kobayashi, Ryo Nozu, Masaru Nakamura. Role of estrogen in spermatogenesis in initial phase males of the three-spot wrasse (Halichoeres trimaculatus): effect of aromatase inhibitor on the testis. Developmental dynamics : an official publication of the American Association of Anatomists. 2011 Jan; 240(1):116-21. doi: 10.1002/dvdy.22507. [PMID: 21117145]
  • Karen P Maruska, Berta Levavi-Sivan, Jakob Biran, Russell D Fernald. Plasticity of the reproductive axis caused by social status change in an african cichlid fish: I. Pituitary gonadotropins. Endocrinology. 2011 Jan; 152(1):281-90. doi: 10.1210/en.2010-0875. [PMID: 21068157]
  • M F S Ismail, S S Siraj, S K Daud, S A Harmin. Association of annual hormonal profile with gonad maturity of mahseer (Tor tambroides) in captivity. General and comparative endocrinology. 2011 Jan; 170(1):125-30. doi: 10.1016/j.ygcen.2010.09.021. [PMID: 20888822]
  • Jun Kitano, Yui Kawagishi, Seiichi Mori, Catherine L Peichel, Takashi Makino, Masakado Kawata, Makoto Kusakabe. Divergence in sex steroid hormone signaling between sympatric species of Japanese threespine stickleback. PloS one. 2011; 6(12):e29253. doi: 10.1371/journal.pone.0029253. [PMID: 22216225]
  • Amy L Filby, Gregory C Paull, Emily J Bartlett, Katrien J W Van Look, Charles R Tyler. Physiological and health consequences of social status in zebrafish (Danio rerio). Physiology & behavior. 2010 Dec; 101(5):576-87. doi: 10.1016/j.physbeh.2010.09.004. [PMID: 20851709]
  • Sean L Divers, H James McQuillan, Hajime Matsubara, Takashi Todo, P Mark Lokman. Effects of reproductive stage and 11-ketotestosterone on LPL mRNA levels in the ovary of the shortfinned eel. Journal of lipid research. 2010 Nov; 51(11):3250-8. doi: 10.1194/jlr.m009027. [PMID: 20713648]
  • Liliya Bykova, Stephanie A Archer-Hartmann, Lisa A Holland, Luke R Iwanowicz, Vicki S Blazer. Steroid determination in fish plasma using capillary electrophoresis. Environmental toxicology and chemistry. 2010 Sep; 29(9):1950-6. doi: 10.1002/etc.252. [PMID: 20821652]
  • Peter Paulos, Tamsin J Runnalls, Gopi Nallani, Tom La Point, Alexander P Scott, John P Sumpter, Duane B Huggett. Reproductive responses in fathead minnow and Japanese medaka following exposure to a synthetic progestin, Norethindrone. Aquatic toxicology (Amsterdam, Netherlands). 2010 Aug; 99(2):256-62. doi: 10.1016/j.aquatox.2010.05.001. [PMID: 20617545]
  • S C Mills, J Mourier, R Galzin. Plasma cortisol and 11-ketotestosterone enzyme immunoassay (EIA) kit validation for three fish species: the orange clownfish Amphiprion percula, the orangefin anemonefish Amphiprion chrysopterus and the blacktip reef shark Carcharhinus melanopterus. Journal of fish biology. 2010 Aug; 77(3):769-77. doi: 10.1111/j.1095-8649.2010.02693.x. [PMID: 20701653]
  • Kimberly A Hruska, Scott G Hinch, Michael C Healey, David A Patterson, Stefan Larsson, Anthony P Farrell. Influences of sex and activity level on physiological changes in individual adult sockeye salmon during rapid senescence. Physiological and biochemical zoology : PBZ. 2010 Jul; 83(4):663-76. doi: 10.1086/652411. [PMID: 20482369]
  • Sabina Ruksana, Narayan P Pandit, Masaru Nakamura. Efficacy of exemestane, a new generation of aromatase inhibitor, on sex differentiation in a gonochoristic fish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2010 Jun; 152(1):69-74. doi: 10.1016/j.cbpc.2010.02.014. [PMID: 20193775]
  • Adam S Arterbery, David L Deitcher, Andrew H Bass. Divergent expression of 11beta-hydroxysteroid dehydrogenase and 11beta-hydroxylase genes between male morphs in the central nervous system, sonic muscle and testis of a vocal fish. General and comparative endocrinology. 2010 May; 167(1):44-50. doi: 10.1016/j.ygcen.2010.02.021. [PMID: 20178798]
  • M K Rasheeda, H Kagawa, R Kirubagaran, A Dutta-Gupta, B Senthilkumaran. Cloning, expression and enzyme activity analysis of testicular 11beta-hydroxysteroid dehydrogenase during seasonal cycle and after hCG induction in air-breathing catfish Clarias gariepinus. The Journal of steroid biochemistry and molecular biology. 2010 May; 120(1):1-10. doi: 10.1016/j.jsbmb.2010.02.014. [PMID: 20219674]
  • Anel M Flores-Valverde, Julia Horwood, Elizabeth M Hill. Disruption of the steroid metabolome in fish caused by exposure to the environmental estrogen 17alpha-ethinylestradiol. Environmental science & technology. 2010 May; 44(9):3552-8. doi: 10.1021/es9039049. [PMID: 20356033]
  • Karen P Maruska, Russell D Fernald. Steroid receptor expression in the fish inner ear varies with sex, social status, and reproductive state. BMC neuroscience. 2010 Apr; 11(?):58. doi: 10.1186/1471-2202-11-58. [PMID: 20433748]
  • Achim Trubiroha, Hana Kroupova, Sven Wuertz, Sabrina N Frank, Bernd Sures, Werner Kloas. Naturally-induced endocrine disruption by the parasite Ligula intestinalis (Cestoda) in roach (Rutilus rutilus). General and comparative endocrinology. 2010 Apr; 166(2):234-40. doi: 10.1016/j.ygcen.2009.08.010. [PMID: 19723526]
  • David S Peñaranda, Luz Pérez, Víctor Gallego, Miguel Jover, Helge Tveiten, Sylvie Baloche, Sylvie Dufour, Juan F Asturiano. Molecular and physiological study of the artificial maturation process in European eel males: from brain to testis. General and comparative endocrinology. 2010 Mar; 166(1):160-71. doi: 10.1016/j.ygcen.2009.08.006. [PMID: 19699741]
  • Chang-Beom Park, Jun-Ya Aoki, Jae-Seong Lee, Masaki Nagae, Young-Don Lee, Yoshitaka Sakakura, Atsushi Hagiwara, Kiyoshi Soyano. The effects of 17beta-estradiol on various reproductive parameters in the hermaphrodite fish Kryptolebias marmoratus. Aquatic toxicology (Amsterdam, Netherlands). 2010 Mar; 96(4):273-9. doi: 10.1016/j.aquatox.2009.11.006. [PMID: 20006390]
  • Hung Quoc Pham, Anh Tuong Nguyen, Mao Dinh Nguyen, Augustine Arukwe. Sex steroid levels, oocyte maturation and spawning performance in Waigieu seaperch (Psammoperca waigiensis) exposed to thyroxin, human chorionic gonadotropin, luteinizing hormone releasing hormone and carp pituitary extract. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2010 Feb; 155(2):223-30. doi: 10.1016/j.cbpa.2009.10.044. [PMID: 19896549]
  • Mário S Diniz, Rita Maurício, Mira Petrovic, Maria J López de Alda, Leonor Amaral, Isabel Peres, Damiá Barceló, Fernando Santana. Assessing the estrogenic potency in a Portuguese wastewater treatment plant using an integrated approach. Journal of environmental sciences (China). 2010; 22(10):1613-22. doi: 10.1016/s1001-0742(09)60297-7. [PMID: 21235194]
  • Wei-Li Zhang, Lin-Yan Zhou, Balasubramanian Senthilkumaran, Bao-Feng Huang, Cheni Chery Sudhakumari, Tohru Kobayashi, Yoshitaka Nagahama, De-Shou Wang. Molecular cloning of two isoforms of 11beta-hydroxylase and their expressions in the Nile tilapia, Oreochromis niloticus. General and comparative endocrinology. 2010 Jan; 165(1):34-41. doi: 10.1016/j.ygcen.2009.05.018. [PMID: 19500584]
  • Perrine Geraudie, Marie Gerbron, Christophe Minier. Seasonal variations and alterations of sex steroid levels during the reproductive cycle of male roach (Rutilus rutilus). Marine environmental research. 2010; 69 Suppl(?):S53-5. doi: 10.1016/j.marenvres.2009.11.008. [PMID: 20006903]
  • Peter J Allen, Molly A H Webb, Eli Cureton, Ronald M Bruch, Cameron C Barth, Stephan J Peake, W Gary Anderson. Calcium regulation in wild populations of a freshwater cartilaginous fish, the lake sturgeon Acipenser fulvescens. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2009 Dec; 154(4):437-50. doi: 10.1016/j.cbpa.2009.07.014. [PMID: 19651230]
  • A Corriero, A Medina, C C Mylonas, C R Bridges, N Santamaria, M Deflorio, M Losurdo, R Zupa, H Gordin, F de la Gandara, A Belmonte Rìos, C Pousis, G De Metrio. Proliferation and apoptosis of male germ cells in captive Atlantic bluefin tuna (Thunnus thynnus L.) treated with gonadotropin-releasing hormone agonist (GnRHa). Animal reproduction science. 2009 Dec; 116(3-4):346-57. doi: 10.1016/j.anireprosci.2009.02.013. [PMID: 19304415]
  • Fagen Zhang, Michael J Bartels, David R Geter, Melissa S Carr, Lynn E McClymount, Troy A Marino, Gary M Klecka. Simultaneous quantitation of testosterone, estradiol, ethinyl estradiol, and 11-ketotestosterone in fathead minnow fish plasma by liquid chromatography/positive atmospheric pressure photoionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. 2009 Dec; 23(23):3637-46. doi: 10.1002/rcm.4298. [PMID: 19890953]
  • M Sebire, I Katsiadaki, A P Scott. Further refinement of the non-invasive procedure for measuring steroid production in the male three-spined stickleback Gasterosteus aculeatus. Journal of fish biology. 2009 Nov; 75(8):2082-94. doi: 10.1111/j.1095-8649.2009.02409.x. [PMID: 20738674]
  • S Milla, S N M Mandiki, P Hubermont, C Rougeot, C Mélard, P Kestemont. Ovarian steroidogenesis inhibition by constant photothermal conditions is caused by a lack of gonadotropin stimulation in Eurasian perch. General and comparative endocrinology. 2009 Sep; 163(3):242-50. doi: 10.1016/j.ygcen.2009.04.010. [PMID: 19389402]
  • Ana Rocha, Silvia Zanuy, Manuel Carrillo, Ana Gómez. Seasonal changes in gonadal expression of gonadotropin receptors, steroidogenic acute regulatory protein and steroidogenic enzymes in the European sea bass. General and comparative endocrinology. 2009 Jul; 162(3):265-75. doi: 10.1016/j.ygcen.2009.03.023. [PMID: 19345689]
  • Benjamin de Montgolfier, Aliou Faye, Céline Audet, Daniel G Cyr. Seasonal variations in testicular connexin levels and their regulation in the brook trout, Salvelinus fontinalis. General and comparative endocrinology. 2009 Jul; 162(3):276-85. doi: 10.1016/j.ygcen.2009.03.025. [PMID: 19348806]
  • Martín Blasco, Pedro Carriquiriborde, Damián Marino, Alicia E Ronco, Gustavo M Somoza. A quantitative HPLC-MS method for the simultaneous determination of testosterone, 11-ketotestosterone and 11-beta hydroxyandrostenedione in fish serum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 May; 877(14-15):1509-15. doi: 10.1016/j.jchromb.2009.03.028. [PMID: 19369122]
  • Håkan Berg, Nikolai Scherbak, Harri Liimatta, Erik Hoffmann, Johnny Karlsson, Per-Erik Olsson. Characterization of antibodies for quantitative determination of spiggin protein levels in male and female three-spined stickleback (Gasterosteus aculeatus). Reproductive biology and endocrinology : RB&E. 2009 May; 7(?):46. doi: 10.1186/1477-7827-7-46. [PMID: 19442269]
  • James D Salierno, Andrew S Kane. 17alpha-ethinylestradiol alters reproductive behaviors, circulating hormones, and sexual morphology in male fathead minnows (Pimephales promelas). Environmental toxicology and chemistry. 2009 May; 28(5):953-61. doi: 10.1897/08-111.1. [PMID: 19650224]
  • Takeshi A Onuma, Keita Makino, Masatoshi Ban, Hironori Ando, Masa-aki Fukuwaka, Tomonori Azumaya, Penny Swanson, Akihisa Urano. Elevation of the plasma level of insulin-like growth factor-I with reproductive maturation prior to initiation of spawning migration of chum salmon. Annals of the New York Academy of Sciences. 2009 Apr; 1163(?):497-500. doi: 10.1111/j.1749-6632.2008.03668.x. [PMID: 19456398]
  • Matthew D Taves, Julie K Desjardins, Sandeep Mishra, Sigal Balshine. Androgens and dominance: sex-specific patterns in a highly social fish (Neolamprologus pulcher). General and comparative endocrinology. 2009 Apr; 161(2):202-7. doi: 10.1016/j.ygcen.2008.12.018. [PMID: 19174165]
  • Karen P Maruska, Wayne J Korzan, Allen F Mensinger. Individual, temporal, and population-level variations in circulating 11-ketotestosterone and 17beta-estradiol concentrations in the oyster toadfish Opsanus tau. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2009 Apr; 152(4):569-78. doi: 10.1016/j.cbpa.2009.01.002. [PMID: 19167510]
  • Fernanda F L Almeida, Geir Lasse Taranger, Birgitta Norberg, Orjan Karlsen, Jan Bogerd, Rüdiger W Schulz. Photoperiod-modulated testis maturation in Atlantic cod (Gadus morhua, L.). Biology of reproduction. 2009 Apr; 80(4):631-40. doi: 10.1095/biolreprod.108.071340. [PMID: 19038862]
  • F Chu-Koo, R Dugué, M Alván Aguilar, A Casanova Daza, F Alcántara Bocanegra, C Chávez Veintemilla, F Duponchelle, J-F Renno, Salvador Tello, J Nuñez. Gender determination in the Paiche or Pirarucu (Arapaima gigas) using plasma vitellogenin, 17beta-estradiol, and 11-ketotestosterone levels. Fish physiology and biochemistry. 2009 Mar; 35(1):125-36. doi: 10.1007/s10695-008-9211-8. [PMID: 19189239]
  • T Randak, V Zlabek, J Pulkrabova, J Kolarova, H Kroupova, Z Siroka, J Velisek, Z Svobodova, J Hajslova. Effects of pollution on chub in the River Elbe, Czech Republic. Ecotoxicology and environmental safety. 2009 Mar; 72(3):737-46. doi: 10.1016/j.ecoenv.2008.09.020. [PMID: 19019432]
  • Maria Jose Bayarri, Silvia Zanuy, Ozlem Yilmaz, Manuel Carrillo. Effects of continuous light on the reproductive system of European sea bass gauged by alterations of circadian variations during their first reproductive cycle. Chronobiology international. 2009 Feb; 26(2):184-99. doi: 10.1080/07420520902758311. [PMID: 19212836]
  • Christopher G Mull, Christopher G Lowe, Kelly A Young. Photoperiod and water temperature regulation of seasonal reproduction in male round stingrays (Urobatis halleri). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2008 Dec; 151(4):717-25. doi: 10.1016/j.cbpa.2008.08.029. [PMID: 18793743]
  • Stine Lastein, Erik Höglund, Ian Mayer, Oyvind Overli, Kjell B Døving. Female crucian carp, Carassius carassius, lose predator avoidance behavior when getting ready to mate. Journal of chemical ecology. 2008 Nov; 34(11):1487-91. doi: 10.1007/s10886-008-9553-9. [PMID: 18937012]
  • David Gonçalves, Magda Teles, João Alpedrinha, Rui F Oliveira. Brain and gonadal aromatase activity and steroid hormone levels in female and polymorphic males of the peacock blenny Salaria pavo. Hormones and behavior. 2008 Nov; 54(5):717-25. doi: 10.1016/j.yhbeh.2008.07.014. [PMID: 18760279]
  • Liliya Bykova, Lisa A Holland. Stacking enhanced determination of steroids by CE. Electrophoresis. 2008 Sep; 29(18):3794-800. doi: 10.1002/elps.200800090. [PMID: 18850649]
  • S Nadzialek, L Spanò, S N M Mandiki, P Kestemont. High doses of atrazine do not disrupt activity and expression of aromatase in female gonads of juvenile goldfish (Carassius auratus L.). Ecotoxicology (London, England). 2008 Aug; 17(6):464-70. doi: 10.1007/s10646-008-0198-9. [PMID: 18286371]
  • Tobias S Coe, Patrick B Hamilton, David Hodgson, Gregory C Paull, Jamie R Stevens, Katie Sumner, Charles R Tyler. An environmental estrogen alters reproductive hierarchies, disrupting sexual selection in group-spawning fish. Environmental science & technology. 2008 Jul; 42(13):5020-5. doi: 10.1021/es800277q. [PMID: 18678043]
  • M-E Sébert, C Legros, F-A Weltzien, B Malpaux, P Chemineau, S Dufour. Melatonin activates brain dopaminergic systems in the eel with an inhibitory impact on reproductive function. Journal of neuroendocrinology. 2008 Jul; 20(7):917-29. doi: 10.1111/j.1365-2826.2008.01744.x. [PMID: 18445127]
  • Pratap B Singh, Vandana Singh. Cypermethrin induced histological changes in gonadotrophic cells, liver, gonads, plasma levels of estradiol-17beta and 11-ketotestosterone, and sperm motility in Heteropneustes fossilis (Bloch). Chemosphere. 2008 Jun; 72(3):422-31. doi: 10.1016/j.chemosphere.2008.02.026. [PMID: 18374387]
  • E Chaves-Pozo, F J Arjona, A García-López, A García-Alcázar, J Meseguer, A García-Ayala. Sex steroids and metabolic parameter levels in a seasonal breeding fish (Sparus aurata L.). General and comparative endocrinology. 2008 May; 156(3):531-6. doi: 10.1016/j.ygcen.2008.03.004. [PMID: 18407272]
  • Cynthia A Awruch, Ned W Pankhurst, Stewart D Frusher, John D Stevens. Endocrine and morphological correlates of reproduction in the draughtboard shark Cephaloscyllium laticeps (Elasmobranchii: Scyliorhinidae). Journal of experimental zoology. Part A, Ecological genetics and physiology. 2008 Apr; 309(4):184-97. doi: 10.1002/jez.445. [PMID: 18278802]
  • Takashi Yazawa, Miki Uesaka, Yoshihiko Inaoka, Tetsuya Mizutani, Toshio Sekiguchi, Takashi Kajitani, Takeshi Kitano, Akihiro Umezawa, Kaoru Miyamoto. Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen: conservation and evolution of the androgen metabolic pathway. Endocrinology. 2008 Apr; 149(4):1786-92. doi: 10.1210/en.2007-1015. [PMID: 18162527]
  • Rüdiger W Schulz, Maurice Liemburg, Angel García-López, Wytske van Dijk, Jan Bogerd. Androgens modulate testicular androgen production in African catfish (Clarias gariepinus) depending on the stage of maturity and type of androgen. General and comparative endocrinology. 2008 Mar; 156(1):154-63. doi: 10.1016/j.ygcen.2008.01.002. [PMID: 18262184]
  • Eri Iwata, Yukiko Nagai, Mai Hyoudou, Hideaki Sasaki. Social environment and sex differentiation in the false clown anemonefish, Amphiprion ocellaris. Zoological science. 2008 Feb; 25(2):123-8. doi: 10.2108/zsj.25.123. [PMID: 18533742]
  • N W Pankhurst, Q P Fitzgibbon, P M Pankhurst, H R King. Habitat-related variation in reproductive endocrine condition in the coral reef damselfish Acanthochromis polyacanthus. General and comparative endocrinology. 2008 Jan; 155(2):386-97. doi: 10.1016/j.ygcen.2007.07.003. [PMID: 17761181]
  • Eduardo N Barata, Peter C Hubbard, Olinda G Almeida, António Miranda, Adelino Vm Canário. Male urine signals social rank in the Mozambique tilapia (Oreochromis mossambicus). BMC biology. 2007 Dec; 5(?):54. doi: 10.1186/1741-7007-5-54. [PMID: 18076759]
  • C A Landry, S L Steele, S Manning, A O Cheek. Long term hypoxia suppresses reproductive capacity in the estuarine fish, Fundulus grandis. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2007 Oct; 148(2):317-23. doi: 10.1016/j.cbpa.2007.04.023. [PMID: 17596980]
  • Tamsin J Runnalls, David N Hala, John P Sumpter. Preliminary studies into the effects of the human pharmaceutical Clofibric acid on sperm parameters in adult Fathead minnow. Aquatic toxicology (Amsterdam, Netherlands). 2007 Aug; 84(1):111-8. doi: 10.1016/j.aquatox.2007.06.005. [PMID: 17643504]
  • Marie-Emilie Sébert, Aline Amérand, Aurélie Vettier, Finn-Arne Weltzien, Catherine Pasqualini, Philippe Sébert, Sylvie Dufour. Effects of high hydrostatic pressure on the pituitary-gonad axis in the European eel, Anguilla anguilla (L.). General and comparative endocrinology. 2007 Aug; 153(1-3):289-98. doi: 10.1016/j.ygcen.2007.01.009. [PMID: 17324430]