1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione (BioDeep_00000172500)

   

human metabolite blood metabolite natural product


代谢物信息卡片


1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione

化学式: C19H16O4 (308.1049)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: O=C(C=Cc1ccc(O)cc1)CC(=O)C=Cc1ccc(O)cc1
InChI: InChI=1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2

描述信息

同义名列表

1 个代谢物同义名

1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

33 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

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  • Rui Li, Xue Qiao, Qingyan Li, Rong He, Min Ye, Cheng Xiang, Xionghao Lin, Dean Guo. Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Sep; 879(26):2751-8. doi: 10.1016/j.jchromb.2011.07.042. [PMID: 21856253]
  • Xiao-Ju Yong, Wei Ding, Yong-Qiang Zhang, Ming-Xia Li. [Bioactivity and action modes of bisdemethoxycurcumin against Tetranychus cinnabarinus Bois. (Acari:Tetranychidae)]. Ying yong sheng tai xue bao = The journal of applied ecology. 2011 Jun; 22(6):1592-8. doi: ". [PMID: 21941764]
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  • Valentina Basile, Erika Ferrari, Sandra Lazzari, Silvia Belluti, Francesca Pignedoli, Carol Imbriano. Curcumin derivatives: molecular basis of their anti-cancer activity. Biochemical pharmacology. 2009 Nov; 78(10):1305-15. doi: 10.1016/j.bcp.2009.06.105. [PMID: 19580791]
  • Toshiyuki Matsunaga, Satoshi Endo, Midori Soda, Hai-Tao Zhao, Ossama El-Kabbani, Kazuo Tajima, Akira Hara. Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: probing the active site of the enzyme with molecular modeling and site-directed mutagenesis. Biochemical and biophysical research communications. 2009 Nov; 389(1):128-32. doi: 10.1016/j.bbrc.2009.08.107. [PMID: 19706287]
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  • Monica Saladini, Sandra Lazzari, Francesca Pignedoli, Roberto Rosa, Ferdinando Spagnolo, Erika Ferrari. New synthetic glucosyl-curcuminoids, and their (1)H and (13)C NMR characterization, from Curcuma longa L. Plant foods for human nutrition (Dordrecht, Netherlands). 2009 Sep; 64(3):224-9. doi: 10.1007/s11130-009-0122-3. [PMID: 19462241]
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  • Anusuya Srivivasan, Venugopal P Menon, Viswanathan Periaswamy, K N Rajasekaran. Protection of pancreatic beta-cell by the potential antioxidant bis-o-hydroxycinnamoyl methane, analogue of natural curcuminoid in experimental diabetes. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 2003 Sep; 6(3):327-33. doi: NULL. [PMID: 14738713]
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  • T Devasena, K N Rajasekaran, Venugopal P Menon. Bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis. Pharmacological research. 2002 Jul; 46(1):39-45. doi: 10.1016/s1043-6618(02)00043-9. [PMID: 12208119]