2-(10-Heptadecenyl)-6-hydroxybenzoic acid (BioDeep_00000017226)

 

Secondary id: BioDeep_00000621973

human metabolite PANOMIX_OTCML-2023 Antitumor activity


代谢物信息卡片


Ginkgolic acid C17:1, primary pharmaceutical reference standard

化学式: C24H38O3 (374.2820798)
中文名称: 银杏酸(C17:1), 银杏酸 C17:1, 银杏酸 C17-1, 银杏酸C17-1
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 11.61%

分子结构信息

SMILES: CCCCCCC=CCCCCCCCCCC1=C(C(=CC=C1)O)C(=O)O
InChI: InChI=1S/C24H38O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21-19-17-20-22(25)23(21)24(26)27/h7-8,17,19-20,25H,2-6,9-16,18H2,1H3,(H,26,27)/b8-7-

描述信息

2-(10-Heptadecenyl)-6-hydroxybenzoic acid is found in fats and oils. 2-(10-Heptadecenyl)-6-hydroxybenzoic acid is isolated from Ginkgo biloba (ginkgo).
2-(10-Heptadecenyl)-6-hydroxybenzoic acid is a natural product found in Knema laurina, Ginkgo biloba, and Spondias mombin with data available.
Isolated from Ginkgo biloba (ginkgo). 2-(10-Heptadecenyl)-6-hydroxybenzoic acid is found in fats and oils.
Ginkgolic acid C17:1, extracted from Ginkgo biloba Leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase. Ginkgolic acid C17:1 has anticancer effects[1].
Ginkgolic acid C17:1, extracted from Ginkgo biloba Leaves, suppresses constitutive and inducible STAT3 activation through induction of PTEN and SHP-1 tyrosine phosphatase. Ginkgolic acid C17:1 has anticancer effects[1].

同义名列表

26 个代谢物同义名

Ginkgolic acid C17:1, primary pharmaceutical reference standard; 2-[(10Z)-heptadec-10-en-1-yl]-6-hydroxybenzoic acid; Benzoic acid,2-(10Z)-10-heptadecen-1-yl-6-hydroxy-; Benzoic acid, 2-(10-heptadecenyl)-6-hydroxy-, (Z)-; Benzoic acid, 2-(10Z)-heptadecen-1-yl, -6-hydroxy-; (Z)-2-(Heptadec-10-en-1-yl)-6-hydroxybenzoic acid; Benzoic acid, 2-(10Z)-heptadecen-1-yl, 6-hydroxy-; 2-[(10Z)-Heptadec-10-en-1-yl]-6-hydroxybenzoate; 2-[(Z)-heptadec-10-enyl]-6-hydroxybenzoic acid; 2-(10-Heptadecenyl)-6-hydroxybenzoic acid, 9CI; 6-[(z)-10-heptadecenyl]-2-hydroxybenzoic acid; [(E)-heptadec-15-en-8-yl] 2-hydroxybenzoate; 2-(10-Heptadecenyl)-6-hydroxybenzoic acid; Ginkgolic acid C17:1, analytical standard; (E)-Heptadec-15-en-8-yl 2-hydroxybenzoate; 6-[10(Z)-heptade-cenyljsalicylic acid; 2-(10-Heptadecenyl)-6-hydroxybenzoate; 6-[(10Z)-Heptadecenyl]salicylic acid; 6-(10Z-heptadecenyl)-salicylicacid; 6-(10-Heptadecenyl)salicylic acid; Ginkgolic acid C17:1; Ginkgolic Acid C17-1; Ginkgolic acid 17:1; Ginkgolic Acid C17; Ginkgolic acid II; Ginkgolic



数据库引用编号

11 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Joonseok Oh, In Hyun Hwang, Chang-Eui Hong, Su-Yun Lyu, MinKyun Na. Inhibition of fatty acid synthase by ginkgolic acids from the leaves of Ginkgo biloba and their cytotoxic activity. Journal of enzyme inhibition and medicinal chemistry. 2013 Jun; 28(3):565-8. doi: 10.3109/14756366.2012.658786. [PMID: 22380770]
  • Maciej A Pszczolkowski, Kevin Durden, Samantha Sellars, Brian Cowell, John J Brown. Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples. Journal of agricultural and food chemistry. 2011 Oct; 59(20):10879-86. doi: 10.1021/jf202386c. [PMID: 21905729]
  • Muhammad Nadeem Akhtar, Kok Wai Lam, Faridah Abas, Maulidiani, Syahida Ahmad, Syed Adnan Ali Shah, Atta-Ur-Rahman, M Iqbal Choudhary, Nordin Hj Lajis. New class of acetylcholinesterase inhibitors from the stem bark of Knema laurina and their structural insights. Bioorganic & medicinal chemistry letters. 2011 Jul; 21(13):4097-103. doi: 10.1016/j.bmcl.2011.04.065. [PMID: 21641207]
  • D Wang, T J Girard, T P Kasten, R M LaChance, M A Miller-Wideman, R C Durley. Inhibitory activity of unsaturated fatty acids and anacardic acids toward soluble tissue factor-factor VIIa complex. Journal of natural products. 1998 Nov; 61(11):1352-5. doi: 10.1021/np980117p. [PMID: 9834151]
  • J S Lee, Y S Cho, E J Park, J Kim, W K Oh, H S Lee, J S Ahn. Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba. Journal of natural products. 1998 Jul; 61(7):867-71. doi: 10.1021/np970367q. [PMID: 9677265]