9-Hpode (BioDeep_00000171801)

   

human metabolite blood metabolite natural product


代谢物信息卡片


9-hydroperoxyoctadeca-10,12-dienoic acid

化学式: C18H32O4 (312.2300472)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 5.1%

分子结构信息

SMILES: CCCCC/C=C\C=C\[C@H](CCCCCCCC(=O)O)OO
InChI: InChI=1S/C18H32O4/c1-2-3-4-5-6-8-11-14-17(22-21)15-12-9-7-10-13-16-18(19)20/h6,8,11,14,17,21H,2-5,7,9-10,12-13,15-16H2,1H3,(H,19,20)

描述信息

同义名列表

2 个代谢物同义名

9-hydroperoxyoctadeca-10,12-dienoic acid; 9-HpODE



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

27 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Anna Z Pollack, Enrique F Schisterman, Lynn R Goldman, Sunni L Mumford, Neil J Perkins, Michael S Bloom, Carole B Rudra, Richard W Browne, Jean Wactawski-Wende. Relation of blood cadmium, lead, and mercury levels to biomarkers of lipid peroxidation in premenopausal women. American journal of epidemiology. 2012 Apr; 175(7):645-52. doi: 10.1093/aje/kwr375. [PMID: 22302120]
  • Luc H Boudreau, Jacques Maillet, Luc M LeBlanc, Jacques Jean-François, Mohamed Touaibia, Nicolas Flamand, Marc E Surette. Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes. PloS one. 2012; 7(2):e31833. doi: 10.1371/journal.pone.0031833. [PMID: 22347509]
  • Virginie Gosset, Nicolas Harmel, Cornelia Göbel, Frédéric Francis, Eric Haubruge, Jean-Paul Wathelet, Patrick du Jardin, Ivo Feussner, Marie-Laure Fauconnier. Attacks by a piercing-sucking insect (Myzus persicae Sultzer) or a chewing insect (Leptinotarsa decemlineata Say) on potato plants (Solanum tuberosum L.) induce differential changes in volatile compound release and oxylipin synthesis. Journal of experimental botany. 2009; 60(4):1231-40. doi: 10.1093/jxb/erp015. [PMID: 19221142]
  • Richard K Hughes, Faridoon K Yousafzai, Ruth Ashton, Ivan R Chechetkin, Shirley A Fairhurst, Mats Hamberg, Rod Casey. Evidence for communality in the primary determinants of CYP74 catalysis and of structural similarities between CYP74 and classical mammalian P450 enzymes. Proteins. 2008 Sep; 72(4):1199-211. doi: 10.1002/prot.22012. [PMID: 18338380]
  • Alexander N Grechkin, Fredi Brühlmann, Lucia S Mukhtarova, Yuri V Gogolev, Mats Hamberg. Hydroperoxide lyases (CYP74C and CYP74B) catalyze the homolytic isomerization of fatty acid hydroperoxides into hemiacetals. Biochimica et biophysica acta. 2006 Dec; 1761(12):1419-28. doi: 10.1016/j.bbalip.2006.09.002. [PMID: 17049304]
  • Hideo Iwahashi, Tomihiro Hirai, Kazumasa Kumamoto. High performance liquid chromatography/electron spin resonance/mass spectrometry analyses of radicals formed in an anaerobic reaction of 9- (or 13-) hydroperoxide octadecadienoic acids with ferrous ions. Journal of chromatography. A. 2006 Nov; 1132(1-2):67-75. doi: 10.1016/j.chroma.2006.07.028. [PMID: 16889785]
  • Ernst H Oliw, Ulrike Garscha, Tomas Nilsson, Mirela Cristea. Payne rearrangement during analysis of epoxyalcohols of linoleic and alpha-linolenic acids by normal phase liquid chromatography with tandem mass spectrometry. Analytical biochemistry. 2006 Jul; 354(1):111-26. doi: 10.1016/j.ab.2006.04.010. [PMID: 16712763]
  • Hisao Kuroda, Hidetoshi Kojima, Hirotaka Kaneda, Masachika Takashio. Characterization of 9-fatty acid hydroperoxide lyase-like activity in germinating barley seeds that transforms 9(S)-hydroperoxy-10(E),12(Z)-octadecadienoic acid into 2(E)-nonenal. Bioscience, biotechnology, and biochemistry. 2005 Sep; 69(9):1661-8. doi: 10.1271/bbb.69.1661. [PMID: 16195582]
  • Hideto Kimura, Kazushige Yokota. Characterization of metabolic pathway of linoleic acid 9-hydroperoxide in cytosolic fraction of potato tubers and identification of reaction products. Applied biochemistry and biotechnology. 2004 Jul; 118(1-3):115-32. doi: 10.1385/abab:118:1-3:115. [PMID: 15304744]
  • P Spiteller, W Kern, J Reiner, G Spiteller. Aldehydic lipid peroxidation products derived from linoleic acid. Biochimica et biophysica acta. 2001 Apr; 1531(3):188-208. doi: 10.1016/s1388-1981(01)00100-7. [PMID: 11325611]