(2R)-3-Sulfanylpropane-1,2-diol (BioDeep_00000171776)

 

Secondary id: BioDeep_00001871848

human metabolite blood metabolite


代谢物信息卡片


(2R)-3-Sulphanylpropane-1,2-diol

化学式: C3H8O2S (108.0244988)
中文名称: 1-硫代甘油
谱图信息: 最多检出来源 Mus musculus(blood) 50%

分子结构信息

SMILES: C(C(CS)O)O
InChI: InChI=1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

描述信息

同义名列表

22 个代谢物同义名

(2R)-3-Sulphanylpropane-1,2-diol; (2R)-3-Sulfanylpropane-1,2-diol; 1-Mercapto-2,3-propanediol; 3-Mercaptopropane-1,2-diol; 3-Mercapto-1,2-propanediol; 3-sulfanylpropane-1,2-diol; 2,3-Dihydroxypropanethiol; Thioglycerol sodium salt; 1-Thio-2,3-propanediol; alpha-Thiolglycerol; 1-Monothioglycerol; alpha-Thioglycerol; 1-Mercaptoglycerol; Mercaptoglycerol; Monothioglycerin; Monothioglycerol; a-Thiolglycerol; Α-thiolglycerol; 1-Thioglycerol; Thioglycerine; Thioglycerin; Thioglycerol



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Eric V Patridge, Emma S E Eriksson, Philip G Penketh, Raymond P Baumann, Rui Zhu, Krishnamurthy Shyam, Leif A Eriksson, Alan C Sartorelli. 7-Nitro-4-(phenylthio)benzofurazan is a potent generator of superoxide and hydrogen peroxide. Archives of toxicology. 2012 Oct; 86(10):1613-25. doi: 10.1007/s00204-012-0872-9. [PMID: 22669514]
  • Pinki Nandi, Swatilekha Ghosh, Kuladip Jana, Parimal C Sen. Elucidation of the involvement of p14, a sperm protein during maturation, capacitation and acrosome reaction of caprine spermatozoa. PloS one. 2012; 7(1):e30552. doi: 10.1371/journal.pone.0030552. [PMID: 22291985]
  • Chin Wee Tan, Bruce S Gardiner, Yumiko Hirokawa, Meredith J Layton, David W Smith, Antony W Burgess. Wnt signalling pathway parameters for mammalian cells. PloS one. 2012; 7(2):e31882. doi: 10.1371/journal.pone.0031882. [PMID: 22363759]
  • Paul W Burridge, Susan Thompson, Michal A Millrod, Seth Weinberg, Xuan Yuan, Ann Peters, Vasiliki Mahairaki, Vassilis E Koliatsos, Leslie Tung, Elias T Zambidis. A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PloS one. 2011 Apr; 6(4):e18293. doi: 10.1371/journal.pone.0018293. [PMID: 21494607]
  • Chunfeng Ma, Hao Zhou, Bo Wu, Guangzhao Zhang. Preparation of polyurethane with zwitterionic side chains and their protein resistance. ACS applied materials & interfaces. 2011 Feb; 3(2):455-61. doi: 10.1021/am101039q. [PMID: 21222476]
  • Min Kyoung Jeon, Jong-Baeck Lim, Gyun Min Lee. Development of a serum-free medium for in vitro expansion of human cytotoxic T lymphocytes using a statistical design. BMC biotechnology. 2010 Sep; 10(?):70. doi: 10.1186/1472-6750-10-70. [PMID: 20854694]
  • Joshua R Mauney, Aruna Ramachandran, Richard N Yu, George Q Daley, Rosalyn M Adam, Carlos R Estrada. All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms. PloS one. 2010 Jul; 5(7):e11513. doi: 10.1371/journal.pone.0011513. [PMID: 20644631]
  • Sebastian Falk, Irmgard Sinning. cpSRP43 is a novel chaperone specific for light-harvesting chlorophyll a,b-binding proteins. The Journal of biological chemistry. 2010 Jul; 285(28):21655-61. doi: 10.1074/jbc.c110.132746. [PMID: 20498370]
  • Matteo Amelia, Rebecca Flamini, Loredana Latterini. Recovery of CdS nanocrystal defects through conjugation with proteins. Langmuir : the ACS journal of surfaces and colloids. 2010 Jun; 26(12):10129-34. doi: 10.1021/la100249t. [PMID: 20429615]
  • Shih-Ju Chen, Huan-Tsung Chang. Nile red-adsorbed gold nanoparticles for selective determination of thiols based on energy transfer and aggregation. Analytical chemistry. 2004 Jul; 76(13):3727-34. doi: 10.1021/ac049787s. [PMID: 15228347]
  • Hsun Teresa Ku, Nan Zhang, Atsushi Kubo, Ryan O'Connor, Minwei Mao, Gordon Keller, Jonathan S Bromberg. Committing embryonic stem cells to early endocrine pancreas in vitro. Stem cells (Dayton, Ohio). 2004; 22(7):1205-17. doi: 10.1634/stemcells.2004-0027. [PMID: 15579640]
  • Jonas Wetterö, Agneta Askendal, Torbjörn Bengtsson, Pentti Tengvall. On the binding of complement to solid artificial surfaces in vitro. Biomaterials. 2002 Feb; 23(4):981-91. doi: 10.1016/s0142-9612(01)00203-4. [PMID: 11791932]
  • M Brielmeier, J M Béchet, S Suppmann, M Conrad, G Laux, G W Bornkamm. Cloning of phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an anti-apoptotic and growth promoting gene of Burkitt lymphoma cells. BioFactors (Oxford, England). 2001; 14(1-4):179-90. doi: 10.1002/biof.5520140123. [PMID: 11568455]
  • S Kanagaraja, S Alaeddine, C Eriksson, J Lausmaa, P Tengvall, A Wennerberg, H Nygren. Surface characterization, protein adsorption, and initial cell-surface reactions on glutathione and 3-mercapto-1,2,-propanediol immobilized to gold. Journal of biomedical materials research. 1999 Sep; 46(4):582-91. doi: 10.1002/(sici)1097-4636(19990915)46:4<582::aid-jbm17>3.0.co;2-5. [PMID: 10398020]
  • M H Falk, T Meier, R D Issels, M Brielmeier, B Scheffer, G W Bornkamm. Apoptosis in Burkitt lymphoma cells is prevented by promotion of cysteine uptake. International journal of cancer. 1998 Feb; 75(4):620-5. doi: 10.1002/(sici)1097-0215(19980209)75:4<620::aid-ijc21>3.0.co;2-b. [PMID: 9466666]
  • T Mavromoustakos, E Theodoropoulou, D P Yang, S Y Lin, M Koufaki, A Makriyannis. The conformational properties of the antineoplastic ether lipid 1-thiohexadecyl-2-O-methyl-S-glycero-3-phosphocholine. Chemistry and physics of lipids. 1996 Nov; 84(1):21-34. doi: 10.1016/s0009-3084(96)02615-1. [PMID: 8952050]
  • P Tengvall, A Askendal, I Lundström. Complement activation by 3-mercapto-1,2-propanediol immobilized on gold surfaces. Biomaterials. 1996 May; 17(10):1001-7. doi: 10.1016/0142-9612(96)84675-8. [PMID: 8736735]
  • C I Hong, S H An, A Nechaev, A J Kirisits, R Vig, C R West. Synthesis and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugates of optical isomers of ether and thioether lipids. Lipids. 1993 Nov; 28(11):1021-6. doi: 10.1007/bf02537125. [PMID: 8277825]
  • R J Grill, S K Pixley. 2-Mercaptoethanol is a survival factor for olfactory, cortical and hippocampal neurons in short-term dissociated cell culture. Brain research. 1993 Jun; 613(1):168-72. doi: 10.1016/0006-8993(93)90470-8. [PMID: 8348301]
  • U Justesen, G Bojesen. Analysis of some eicosanoids by continuous-flow fast atom bombardment mass spectrometry. Journal of chromatography. 1991 Jan; 562(1-2):59-66. doi: 10.1016/0378-4347(91)80564-s. [PMID: 2026722]
  • Y Iizuka, M J Murphy. Colony formation of granulocyte (CFU-g) and macrophage (CFU-m) precursors in serum- and albumin-free culture: effect of transferrin on clonal growth. Experimental cell biology. 1986; 54(5-6):275-80. doi: 10.1159/000163366. [PMID: 2433167]
  • R S Dhanotiya. Effect of cations on hydrolysis of fructose 1:6 bisphosphate in bull seminal plasma. Archiv fur experimentelle Veterinarmedizin. 1985 Nov; 39(6):869-73. doi: NULL. [PMID: 3006625]
  • D A Nealon, S M Pettit, A R Henderson. Activation of human creatine kinase isoenzymes by pH and various sulfhydryl and chelating agents. Clinical chemistry. 1981 Mar; 27(3):402-4. doi: 10.1093/clinchem/27.3.402. [PMID: 6781791]
  • M G Goodman, W O Weigle. Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol. The Journal of experimental medicine. 1977 Mar; 145(3):473-89. doi: 10.1084/jem.145.3.473. [PMID: 233897]
  • T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1975 Jul; 71(5):457-62. doi: . [PMID: 280]
  • N N Iscove, F Sieber. Erythroid progenitors in mouse bone marrow detected by macroscopic colony formation in culture. Experimental hematology. 1975 Jan; 3(1):32-43. doi: NULL. [PMID: 1157835]