dipyridamole (BioDeep_00000016608)
代谢物信息卡片
dipyridamole
化学式: C24H40N8O4 (504.31723600000004)
中文名称: 双嘧达莫
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CCN(CC1)c1c2c(c(nc(n2)N(CCO)CCO)N2CCCCC2)nc(n1)N(CCO)CCO
InChI: InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2
描述信息
B - Blood and blood forming organs > B01 - Antithrombotic agents > B01A - Antithrombotic agents > B01AC - Platelet aggregation inhibitors excl. heparin
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
1 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:4653
- KEGG: C06964
- KEGGdrug: D00302
- PubChem: 3108
- Metlin: METLIN2341
- DrugBank: DB00975
- ChEMBL: CHEMBL932
- MeSH: Dipyridamole
- CAS: 58-32-2
- MoNA: WA002396
- MoNA: WA002395
- MoNA: WA002394
- RefMet: Dipyridamole
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
- 99506 Heracleum candicans: 10.1007/S11418-008-0266-8
- 489434 Prangos ferulacea:
- 99506 Heracleum candicans: 10.1007/S11418-008-0266-8
- 489434 Prangos ferulacea:
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Rita Pepponi, Roberta De Simone, Chiara De Nuccio, Sergio Visentin, Andrea Matteucci, Antonietta Bernardo, Patrizia Popoli, Antonella Ferrante. Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study.
International journal of molecular sciences.
2022 Mar; 23(7):. doi:
10.3390/ijms23073456. [PMID: 35408815] - Fabio Urbina, Ana C Puhl, Sean Ekins. Recent advances in drug repurposing using machine learning.
Current opinion in chemical biology.
2021 12; 65(?):74-84. doi:
10.1016/j.cbpa.2021.06.001. [PMID: 34274565] - Hanuman Prasad Sharma, Nabanita Halder, Sundararajan Baskar Singh, T Velpandian. Evaluation of the Presence and Functional Importance of Nucleoside Transporters in Lacrimal Gland for Tear Disposition of Intravenously Injected Substrate in Rabbits.
Current eye research.
2021 11; 46(11):1659-1665. doi:
10.1080/02713683.2021.1925698. [PMID: 33941003] - Jibin Li, Nicole Spivey, Svitlana Silchenko, Isabel Gonzalez-Alvarez, Marival Bermejo, Ismael J Hidalgo. A differential equation based modelling approach to predict supersaturation and in vivo absorption from in vitro dissolution-absorption system (idas2) data.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2021 Aug; 165(?):1-12. doi:
10.1016/j.ejpb.2021.05.003. [PMID: 33971275] - Dinala Jialiken, Lichao Qian, Shuai Ren, Lihua Wu, Junyao Xu, Chong Zou. Combined therapy of hypertensive nephropathy with ginkgo leaf extract and dipyridamole injection and antihypertensive drugs: A systematic review and meta-analysis.
Medicine.
2021 May; 100(19):e25852. doi:
10.1097/md.0000000000025852. [PMID: 34106629] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tihamer Molnar, Andrea Horvath, Zsuzsanna Szabo, Zoltan Vamos, Tamas Dóczi, Zsolt Illes. Detection of silent cerebral microcirculatory abnormalities in patients with manifest ischemic coronary disease: a perfusion brain MRI study combined with dipyridamole stress.
Scandinavian cardiovascular journal : SCJ.
2021 Apr; 55(2):97-101. doi:
10.1080/14017431.2020.1821911. [PMID: 32945202] - Vignesh Surianarayanan, Thomas J Hoather, Samuel J Tingle, Emily R Thompson, John Hanley, Colin H Wilson. Interventions for preventing thrombosis in solid organ transplant recipients.
The Cochrane database of systematic reviews.
2021 03; 3(?):CD011557. doi:
10.1002/14651858.cd011557.pub2. [PMID: 33720396] - Chunlong Ma, Jun Wang. Dipyridamole, chloroquine, montelukast sodium, candesartan, oxytetracycline, and atazanavir are not SARS-CoV-2 main protease inhibitors.
Proceedings of the National Academy of Sciences of the United States of America.
2021 02; 118(8):. doi:
10.1073/pnas.2024420118. [PMID: 33568498] - Zhe Li, Yuxi Lin, Yi-You Huang, Runduo Liu, Chang-Guo Zhan, Xin Wang, Hai-Bin Luo. Reply to Ma and Wang: Reliability of various in vitro activity assays on SARS-CoV-2 main protease inhibitors.
Proceedings of the National Academy of Sciences of the United States of America.
2021 02; 118(8):. doi:
10.1073/pnas.2024937118. [PMID: 33568500] - Ryan M Esquejo, Manuel Roqueta-Rivera, Wei Shao, Peter E Phelan, Uthpala Seneviratne, Christopher W Am Ende, Paul M Hershberger, Carolyn E Machamer, Peter J Espenshade, Timothy F Osborne. Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum.
Cell chemical biology.
2021 02; 28(2):169-179.e7. doi:
10.1016/j.chembiol.2020.10.003. [PMID: 33096051] - Tracy Hampton. Autoantibodies May Drive COVID-19 Blood Clots.
JAMA.
2021 02; 325(5):425. doi:
10.1001/jama.2020.25699. [PMID: 33528515] - Majed Malak, Emily Christie, Kevin Wen, Haimanot Wasse, Morteza Hajihosseini, Padma Kaul, Paolo Raggi. Reduced myocardial blood flow reserve in kidney transplant candidates may hamper risk stratification.
Journal of nephrology.
2021 02; 34(1):197-209. doi:
10.1007/s40620-020-00736-x. [PMID: 32277424] - Kholoud F Aliter, Rami A Al-Horani. Potential Therapeutic Benefits of Dipyridamole in COVID-19 Patients.
Current pharmaceutical design.
2021; 27(6):866-875. doi:
10.2174/1381612826666201001125604. [PMID: 33001004] - Christina Mallarino-Haeger, Kaleab Z Abebe, Edwin K Jackson, Ashley Zyhowski, Cynthia Klamar-Blain, Joshua C Cyktor, Diane Comer, Rhonda M Brand, Delbert G Gillespie, Kyle Holleran, John W Mellors, Ian McGowan, Sharon A Riddler, Bernard J C Macatangay. Brief Report: Dipyridamole Decreases Gut Mucosal Regulatory T-Cell Frequencies Among People With HIV on Antiretroviral Therapy.
Journal of acquired immune deficiency syndromes (1999).
2020 12; 85(5):665-669. doi:
10.1097/qai.0000000000002488. [PMID: 33177477] - Zhe Li, Xin Li, Yi-You Huang, Yaoxing Wu, Runduo Liu, Lingli Zhou, Yuxi Lin, Deyan Wu, Lei Zhang, Hao Liu, Ximing Xu, Kunqian Yu, Yuxia Zhang, Jun Cui, Chang-Guo Zhan, Xin Wang, Hai-Bin Luo. Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs.
Proceedings of the National Academy of Sciences of the United States of America.
2020 11; 117(44):27381-27387. doi:
10.1073/pnas.2010470117. [PMID: 33051297] - James J DiNicolantonio, Jorge Barroso-Aranda. Harnessing adenosine A2A receptors as a strategy for suppressing the lung inflammation and thrombotic complications of COVID-19: Potential of pentoxifylline and dipyridamole.
Medical hypotheses.
2020 Oct; 143(?):110051. doi:
10.1016/j.mehy.2020.110051. [PMID: 32650197] - Chin-Yi Liao, Timothy L Tan, Yu-Der Lu, Cheng-Ta Wu, Mel S Lee, Feng-Chih Kuo. Does preoperative dipyridamole-thallium scanning reduce 90-day cardiac complications and 1-year mortality in patients with femoral neck fractures undergoing hemiarthroplasty?.
Journal of orthopaedic surgery and research.
2020 Sep; 15(1):385. doi:
10.1186/s13018-020-01918-w. [PMID: 32894146] - Marion Mussbacher, Teresa L Krammer, Stefan Heber, Waltraud C Schrottmaier, Stephan Zeibig, Hans-Peter Holthoff, David Pereyra, Patrick Starlinger, Matthias Hackl, Alice Assinger. Impact of Anticoagulation and Sample Processing on the Quantification of Human Blood-Derived microRNA Signatures.
Cells.
2020 08; 9(8):. doi:
10.3390/cells9081915. [PMID: 32824700] - Lukas Klumpp, Jennifer Dressman. Physiologically based pharmacokinetic model outputs depend on dissolution data and their input: Case examples glibenclamide and dipyridamole.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2020 Aug; 151(?):105380. doi:
10.1016/j.ejps.2020.105380. [PMID: 32442630] - Yogendra Kanthi, Jason S Knight, Yu Zuo, David J Pinsky. New (re)purpose for an old drug: purinergic modulation may extinguish the COVID-19 thromboinflammatory firestorm.
JCI insight.
2020 07; 5(14):. doi:
10.1172/jci.insight.140971. [PMID: 32530438] - Te-I Chang, Cheng-Hsien Chen, Hui-Ling Hsieh, Chun-You Chen, Shih-Chang Hsu, Ho-Shun Cheng, Wen-Cheng Huang, Yuh-Mou Sue, Yung-Ho Hsu, Feng-Yen Lin, Chun-Ming Shih, Shing-Jong Lin, Po-Hsun Huang, Chung-Te Liu. Effects of cardiovascular medications on primary patency of hemodialysis arteriovenous fistula.
Scientific reports.
2020 07; 10(1):12135. doi:
10.1038/s41598-020-69019-6. [PMID: 32699337] - Shumaila Afrin, Yusra Rahman, Mustafa Alhaji Isa, Shahbaz Ahmed, Mohammad Tabish. Biophysical insights into the binding characteristics of bovine serum albumin with dipyridamole and the influence of molecular interaction with β cyclodextrin.
Journal of biomolecular structure & dynamics.
2020 Jul; 38(10):3046-3058. doi:
10.1080/07391102.2019.1651220. [PMID: 31366288] - Bernard J C Macatangay, Edwin K Jackson, Kaleab Z Abebe, Diane Comer, Joshua Cyktor, Cynthia Klamar-Blain, Luann Borowski, Delbert G Gillespie, John W Mellors, Charles R Rinaldo, Sharon A Riddler. A Randomized, Placebo-Controlled, Pilot Clinical Trial of Dipyridamole to Decrease Human Immunodeficiency Virus-Associated Chronic Inflammation.
The Journal of infectious diseases.
2020 04; 221(10):1598-1606. doi:
10.1093/infdis/jiz344. [PMID: 31282542] - Jian Qiu, Yijun Guo, Xin Xu, Hongmei Yue, Yapei Yang. Ginkgo leaf extract and dipyridamole injection for chronic cor pulmonale: a PRISMA-compliant meta-analysis of randomized controlled trials.
Bioscience reports.
2020 03; 40(3):. doi:
10.1042/bsr20200099. [PMID: 32124923] - Paul Billoir, Thomas Clavier, Arnaud Guilbert, Virginie Barbay, Marie Hélène Chrétien, Marielle Fresel, Caroline Abriou, Christophe Girault, Véronique Le Cam Duchez. [Theophylline adenosine dipyridamole (CTAD) and citrate evaluation to survey unfractionated heparin treatment: a delayed centrifugation validation for anti-Xa measurement?].
Annales de biologie clinique.
2020 02; 78(1):27-34. doi:
10.1684/abc.2020.1525. [PMID: 32108577] - Lampros Lakkas, Katerina K Naka, Aris Bechlioulis, Ioannis Girdis, Anila Duni, Vasileios Koutlas, Maria Moustakli, Christos S Katsouras, Evangelia Dounousi, Lampros K Michalis. The prognostic role of myocardial strain indices and dipyridamole stress test in renal transplantation patients.
Echocardiography (Mount Kisco, N.Y.).
2020 01; 37(1):62-70. doi:
10.1111/echo.14570. [PMID: 31872917] - Bing Huang, Zhanghua Chen, Lanlan Geng, Jun Wang, Huiying Liang, Yujie Cao, Huan Chen, Wanming Huang, Meiling Su, Hanqing Wang, Yanhui Xu, Yukun Liu, Bingtai Lu, Huifang Xian, Huiwen Li, Huilin Li, Lu Ren, Jing Xie, Liping Ye, Hongli Wang, Junhong Zhao, Peiyu Chen, Li Zhang, Shanmeizi Zhao, Ting Zhang, Banglao Xu, Di Che, Wenyue Si, Xiaoqiong Gu, Liang Zeng, Yong Wang, Dingyou Li, Yifan Zhan, David Delfouneso, Andrew M Lew, Jun Cui, Wai Ho Tang, Yan Zhang, Sitang Gong, Fan Bai, Min Yang, Yuxia Zhang. Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways.
Cell.
2019 11; 179(5):1160-1176.e24. doi:
10.1016/j.cell.2019.10.027. [PMID: 31730855] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Carlo Moroni, Stefano Tolone, Francesco Bondanini, Orazio Schillaci, Cesare Affricano, Rosario Cassone, Achille Gaspardone, Carlo Gaudio. Endothelin-1 in hypertensive patients with ischemic heart disease.
Internal and emergency medicine.
2019 10; 14(7):1119-1124. doi:
10.1007/s11739-019-02095-3. [PMID: 31069633] - Paul Billoir, Thomas Clavier, Arnaud Guilbert, Virginie Barbay, Marie Hélène Chrétien, Marielle Fresel, Caroline Abriou, Christophe Girault, Véronique Le Cam Duchez. Is citrate theophylline adenosine dipyridamole (CTAD) better than citrate to survey unfractionated heparin treatment? Has delayed centrifugation a real impact on this survey?.
Journal of thrombosis and thrombolysis.
2019 Aug; 48(2):277-283. doi:
10.1007/s11239-019-01882-1. [PMID: 31098816] - Danai Kitkungvan, Linh Bui, Nils P Johnson, Monica B Patel, Amanda E Roby, Pimprapa Vejpongsa, Asim K Babar, Mohammad Madjid, Angelo Nacimbene, Sachin Kumar, Alexandra DeGolovine, K Lance Gould. Quantitative myocardial perfusion positron emission tomography and caffeine revisited with new insights on major adverse cardiovascular events and coronary flow capacity.
European heart journal. Cardiovascular Imaging.
2019 Jul; 20(7):751-762. doi:
10.1093/ehjci/jez080. [PMID: 31056681] - Joseph Longo, Peter J Mullen, Rosemary Yu, Jenna E van Leeuwen, Mehdi Masoomian, Dixon T S Woon, Yuzhuo Wang, Eric X Chen, Robert J Hamilton, Joan M Sweet, Theodorus H van der Kwast, Neil E Fleshner, Linda Z Penn. An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer.
Molecular metabolism.
2019 07; 25(?):119-130. doi:
10.1016/j.molmet.2019.04.003. [PMID: 31023626] - Shriram M Pathak, Kerstin Julia Schaefer, Masoud Jamei, David B Turner. Biopharmaceutic IVIVE-Mechanistic Modeling of Single- and Two-Phase In Vitro Experiments to Obtain Drug-Specific Parameters for Incorporation Into PBPK Models.
Journal of pharmaceutical sciences.
2019 04; 108(4):1604-1618. doi:
10.1016/j.xphs.2018.11.034. [PMID: 30476508] - Natalia Grañe-Boladeras, Declan Williams, Zlatina Tarmakova, Katarina Stevanovic, Linda A Villani, Pedram Mehrabi, K W Michael Siu, Marçal Pastor-Anglada, Imogen R Coe. Oligomerization of equilibrative nucleoside transporters: a novel regulatory and functional mechanism involving PKC and PP1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2019 03; 33(3):3841-3850. doi:
10.1096/fj.201800440rr. [PMID: 30521377] - Yongyong Liu, Xuqi Wu, Zhenwei Yu. Ginkgo leaf extract and dipyridamole injection as adjuvant treatment for acute cerebral infarction: Protocol for systemic review and meta-analysis of randomized controlled trials.
Medicine.
2019 Feb; 98(8):e14643. doi:
10.1097/md.0000000000014643. [PMID: 30813204] - Qiong Yan, Keisuke Ina, Seiichi Chiba, Huixing Wei, Shuji Tatsukawa, Yoshihisa Fujikura. The signal pathway for the repressive effect of dipyridamole on myofibroblast transdifferentiation.
Journal of cellular and molecular medicine.
2019 02; 23(2):1608-1612. doi:
10.1111/jcmm.14006. [PMID: 30451359] - Atsushi Kambayashi, Jennifer B Dressman. Predicting the Changes in Oral Absorption of Weak Base Drugs Under Elevated Gastric pH Using an In Vitro-In Silico-In Vivo Approach: Case Examples-Dipyridamole, Prasugrel, and Nelfinavir.
Journal of pharmaceutical sciences.
2019 Jan; 108(1):584-591. doi:
10.1016/j.xphs.2018.11.008. [PMID: 30423339] - Sanjaykumar Patel, Wei Zhu, Binfeng Xia, Navneet Sharma, Andre Hermans, Jason D Ehrick, Filippos Kesisoglou, Justin Pennington. Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs.
Journal of pharmaceutical sciences.
2019 01; 108(1):574-583. doi:
10.1016/j.xphs.2018.10.051. [PMID: 30395833] - Alessandro Mantovani, Stefano Bonapace, Gianluigi Lunardi, Matteo Salgarello, Clementina Dugo, Stefania Gori, Enrico Barbieri, Giuseppe Verlato, Reijo Laaksonen, Christopher D Byrne, Giovanni Targher. Association of Plasma Ceramides With Myocardial Perfusion in Patients With Coronary Artery Disease Undergoing Stress Myocardial Perfusion Scintigraphy.
Arteriosclerosis, thrombosis, and vascular biology.
2018 12; 38(12):2854-2861. doi:
10.1161/atvbaha.118.311927. [PMID: 30571175] - Di Tan, Jia-Rui Wu, Ying-Ying Cui, Yi Zhao, Dan Zhang, Shi Liu, Bing Zhang. Ginkgo Leaf Extract and Dipyridamole Injection as Adjuvant Treatment for Angina Pectoris: A Meta-Analysis of 41 Randomized Controlled Trials.
Chinese journal of integrative medicine.
2018 Dec; 24(12):930-937. doi:
10.1007/s11655-018-2557-6. [PMID: 29752694] - Yuko Shima, Koichi Nakanishi, Yoshitsugu Kaku, Kenji Ishikura, Hiroshi Hataya, Takeshi Matsuyama, Masataka Honda, Mayumi Sako, Kandai Nozu, Ryojiro Tanaka, Kazumoto Iijima, Norishige Yoshikawa. Combination therapy with or without warfarin and dipyridamole for severe childhood IgA nephropathy: an RCT.
Pediatric nephrology (Berlin, Germany).
2018 11; 33(11):2103-2112. doi:
10.1007/s00467-018-4011-6. [PMID: 29987456] - Yufeng Zhang, Han Wan, Maosheng Du, Huiling Deng, Jia Fu, Yu Zhang, Xiaoyan Wang, Ruiqing Liu. Capillary leak syndrome and aseptic meningitis in a patient with Kawasaki disease: A case report.
Medicine.
2018 Jun; 97(23):e10716. doi:
10.1097/md.0000000000010716. [PMID: 29879013] - Amita Ray, Sujoy Ray. Epidural therapy for the treatment of severe pre-eclampsia in non labouring women.
The Cochrane database of systematic reviews.
2017 11; 11(?):CD009540. doi:
10.1002/14651858.cd009540.pub2. [PMID: 29181841] - Tiziana Sampietro, Francesco Sbrana, Emilio Maria Pasanisi, Federico Bigazzi, Christina Petersen, Michele Coceani, Beatrice Dal Pino, Andrea Ripoli, Mascia Pianelli, Roberta Luciani. LDL apheresis improves coronary flow reserve on the left anterior descending artery in patients with familial hypercholesterolemia and chronic ischemic heart disease.
Atherosclerosis. Supplements.
2017 Nov; 30(?):135-140. doi:
10.1016/j.atherosclerosissup.2017.05.038. [PMID: 29096829] - Fanny A Granat, Anne Geffré, Laetitia A Lucarelli, Jean-Pierre D Braun, Catherine Trumel, Nathalie H Bourgès-Abella. Evaluation of CTAD (citrate-theophylline-adenosine-dipyridamole) as a universal anticoagulant in dogs.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
2017 Sep; 29(5):676-682. doi:
10.1177/1040638717713793. [PMID: 28673194] - Yasuhiro Tsume, Kazuki Matsui, Amanda L Searls, Susumu Takeuchi, Gregory E Amidon, Duxin Sun, Gordon L Amidon. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2017 May; 102(?):126-139. doi:
10.1016/j.ejps.2017.02.042. [PMID: 28263914] - Kazuki Matsui, Yasuhiro Tsume, Susumu Takeuchi, Amanda Searls, Gordon L Amidon. Utilization of Gastrointestinal Simulator, an in Vivo Predictive Dissolution Methodology, Coupled with Computational Approach To Forecast Oral Absorption of Dipyridamole.
Molecular pharmaceutics.
2017 04; 14(4):1181-1189. doi:
10.1021/acs.molpharmaceut.6b01063. [PMID: 28231003] - Fanny Granat, Céline Monzali, Elisabeth Jeunesse, Maud Guerlin, Catherine Trumel, Anne Geffré, Nathalie Bourgès-Abella. Comparison of different anticoagulant associations on haemostasis and biochemical analyses in feline blood specimens.
Journal of feline medicine and surgery.
2017 Apr; 19(4):394-402. doi:
10.1177/1098612x16628579. [PMID: 26887655] - Pitchai Balakumar, Wei Ern WitnessKoe, Yi Syen Gan, Soo Mei JemayPuah, Subramaniam Kuganesswari, Sunil Kumar Prajapati, Rajavel Varatharajan, Sam Annie Jayachristy, Karupiah Sundram, Mohd Baidi Bahari. Effects of pre and post-treatments with dipyridamole in gentamicin-induced acute nephrotoxicity in the rat.
Regulatory toxicology and pharmacology : RTP.
2017 Mar; 84(?):35-44. doi:
10.1016/j.yrtph.2016.12.007. [PMID: 27993652] - Phanekham Souvannamethy. Management of Nephrotic Syndrome: A Case Report from Lao PDR.
Blood purification.
2017; 44 Suppl 1(?):31-34. doi:
10.1159/000479615. [PMID: 28869958] - Kristoffer Flintholm Raft, Daria Frestad, Marie Mide Michelsen, Hannah Elena Suhrs, Anna Bay Rask, Malin Nilsson, Thomas Steffen Hermann, Eva Prescott. Peripheral Endothelial Function and Coronary Flow Velocity Reserve Are Not Associated in Women with Angina and No Obstructive Coronary Artery Disease: The iPOWER Study.
Journal of vascular research.
2017; 54(5):309-319. doi:
10.1159/000479374. [PMID: 28942444] - V Gangadhara N V Prasad, Satyanarayana Achanta, Yathiraja Rao Tammineni, Gopala Reddy Alla, Madhava Rao Thirtham, G S Rao. Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation.
European journal of drug metabolism and pharmacokinetics.
2016 Dec; 41(6):733-741. doi:
10.1007/s13318-015-0302-5. [PMID: 26458556] - Annelaure Damont, Sébastien Goutal, Sylvain Auvity, Héric Valette, Bertrand Kuhnast, Wadad Saba, Nicolas Tournier. Imaging the impact of cyclosporin A and dipyridamole on P-glycoprotein (ABCB1) function at the blood-brain barrier: A [(11)C]-N-desmethyl-loperamide PET study in nonhuman primates.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2016 Aug; 91(?):98-104. doi:
10.1016/j.ejps.2016.06.005. [PMID: 27283486] - S El Messaoudi, F G Russel, A Colbers, C C J G Bandell, P H H van den Broek, D M Burger, G A Rongen, N P Riksen. The effect of dipyridamole on the pharmacokinetics of metformin: a randomized crossover study in healthy volunteers.
European journal of clinical pharmacology.
2016 Jun; 72(6):725-30. doi:
10.1007/s00228-016-2039-8. [PMID: 26979520] - Nikkita Puri, Vinita Mohey, Manjinder Singh, Tajpreet Kaur, Devendra Pathak, Harpal Singh Buttar, Amrit Pal Singh. Dipyridamole attenuates ischemia reperfusion induced acute kidney injury through adenosinergic A1 and A2A receptor agonism in rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2016 Apr; 389(4):361-8. doi:
10.1007/s00210-015-1206-2. [PMID: 26728617] - S El Messaoudi, C W Wouters, H A van Swieten, P Pickkers, L Noyez, P C Kievit, E J Abbink, A Rasing-Hoogveld, T P Bouw, J G Peters, M J H Coenen, A R T Donders, N P Riksen, G A Rongen. Effect of dipyridamole on myocardial reperfusion injury: A double-blind randomized controlled trial in patients undergoing elective coronary artery bypass surgery.
Clinical pharmacology and therapeutics.
2016 Apr; 99(4):381-9. doi:
10.1002/cpt.106. [PMID: 25773594] - Ersagun Karaguzel, Cemil Bayraktar, Omer Kutlu, Esin Yulug, Ahmet Mentese, Ali Ertan Okatan, Fatih Colak, Serap Ozer, Ilke O Kazaz. The possible protective effects of dipyridamole on ischemic reperfusion injury of priapism.
International braz j urol : official journal of the Brazilian Society of Urology.
2016 Jan; 42(1):146-53. doi:
10.1590/s1677-5538.ibju.2015.0072. [PMID: 27136481] - Nehal M Elsherbiny, Mohammed M H Al-Gayyar, Khaled H Abd El Galil. Nephroprotective role of dipyridamole in diabetic nephropathy: Effect on inflammation and apoptosis.
Life sciences.
2015 Dec; 143(?):8-17. doi:
10.1016/j.lfs.2015.10.026. [PMID: 26596562] - Lei Hua, Gui Lai, Liu Zhenjun, Ma Guie. [The study of anticoagulants selection in platelet-rich plasma preparation].
Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery.
2015 Jul; 31(4):295-300. doi:
. [PMID: 26665933] - Bulent Kaya, Eda Altun, Saime Paydas, Mustafa Balal. The efficacy of dipyridamole in the treatment of hypophosphatemia- hypocalcemia for hungry bone syndrome in a hemodialysis patient.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2015 Mar; 26(2):363-5. doi:
10.4103/1319-2442.152518. [PMID: 25758891] - M Cabiati, S Burchielli, M Matteucci, B Svezia, L Panchetti, C Caselli, T Prescimone, M A Morales, S Del Ry. Dipyridamole-induced C-type natriuretic peptide mRNA overexpression in a minipig model of pacing-induced left ventricular dysfunction.
Peptides.
2015 Feb; 64(?):67-73. doi:
10.1016/j.peptides.2015.01.003. [PMID: 25613228] - Pitchai Balakumar, Rajavel Varatharajan, Ying Hui Nyo, Raja Renushia, Devarajan Raaginey, Ann Nah Oh, Shaikh Sohrab Akhtar, Mani Rupeshkumar, Karupiah Sundram, Sokkalingam A Dhanaraj. Fenofibrate and dipyridamole treatments in low-doses either alone or in combination blunted the development of nephropathy in diabetic rats.
Pharmacological research.
2014 Dec; 90(?):36-47. doi:
10.1016/j.phrs.2014.08.008. [PMID: 25263930] - Chi-Chih Hung, Mei-Li Yang, Ming-Yen Lin, Hugo You-Hsien Lin, Lee-Moay Lim, Hung-Tien Kuo, Shang-Jyh Hwang, Jer-Chia Tsai, Hung-Chun Chen. Dipyridamole treatment is associated with improved renal outcome and patient survival in advanced chronic kidney disease.
The Kaohsiung journal of medical sciences.
2014 Dec; 30(12):599-607. doi:
10.1016/j.kjms.2014.10.002. [PMID: 25476097] - Chia-Wen Hsu, Jinghua Zhao, Ruili Huang, Jui-Hua Hsieh, Jon Hamm, Xiaoqing Chang, Keith Houck, Menghang Xia. Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.
Scientific reports.
2014 Sep; 4(?):6437. doi:
10.1038/srep06437. [PMID: 25257666] - T Raczat, L Kraemer, C Gall, D R Weiss, R Eckstein, J Ringwald. The influence of four different anticoagulants on dynamic light scattering of platelets.
Vox sanguinis.
2014 Aug; 107(2):196-9. doi:
10.1111/vox.12150. [PMID: 24712311] - W O Tobin, J A Kinsella, G F Kavanagh, J S O'Donnell, R T McGrath, T Coughlan, D R Collins, D O'Neill, B Egan, S Tierney, T M Feeley, R P Murphy, D J H McCabe. Longitudinal assessment of von Willebrand factor antigen and von Willebrand factor propeptide in response to alteration of antiplatelet therapy after TIA or ischaemic stroke.
Journal of neurology.
2014 Jul; 261(7):1405-12. doi:
10.1007/s00415-014-7362-3. [PMID: 24781842] - Arun Kumar Sharma, Deepa Khanna, Pitchai Balakumar. Low-dose dipyridamole treatment partially prevents diabetes mellitus-induced vascular endothelial and renal abnormalities in rats.
International journal of cardiology.
2014 Mar; 172(2):530-2. doi:
10.1016/j.ijcard.2014.01.053. [PMID: 24495652] - Haruki Higashino, Tsubasa Hasegawa, Mari Yamamoto, Rie Matsui, Yoshie Masaoka, Makoto Kataoka, Shinji Sakuma, Shinji Yamashita. In vitro-in vivo correlation of the effect of supersaturation on the intestinal absorption of BCS Class 2 drugs.
Molecular pharmaceutics.
2014 Mar; 11(3):746-54. doi:
10.1021/mp400465p. [PMID: 24460473] - Yan Chen, Ying Wang, Jing Zhou, Xia Gao, Ding Qu, Congyan Liu. Study on the mechanism of intestinal absorption of epimedins a, B and C in the Caco-2 cell model.
Molecules (Basel, Switzerland).
2014 Jan; 19(1):686-98. doi:
10.3390/molecules19010686. [PMID: 24402200] - Chunmei Wang, Wenwei Lin, Hilaire Playa, Shan Sun, Keyuna Cameron, John K Buolamwini. Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4).
Biochemical pharmacology.
2013 Dec; 86(11):1531-40. doi:
10.1016/j.bcp.2013.08.063. [PMID: 24021350] - Antonino Tuttolomondo, Rosaria Pecoraro, Domenico Di Raimondo, Valentina Arnao, Giuseppe Clemente, Vittoriano Della Corte, Carlo Maida, Irene Simonetta, Giuseppe Licata, Antonio Pinto. Stroke subtypes and their possible implication in stroke prevention drug strategies.
Current vascular pharmacology.
2013 Nov; 11(6):824-37. doi:
10.2174/157016111106140128113705. [PMID: 24484464] - Abdel Douiri, Christopher McKevitt, Eva S Emmett, Anthony G Rudd, Charles D A Wolfe. Long-term effects of secondary prevention on cognitive function in stroke patients.
Circulation.
2013 Sep; 128(12):1341-8. doi:
10.1161/circulationaha.113.002236. [PMID: 23935013] - Sumeeta Warraich, Derek B J Bone, Diana Quinonez, Hisataka Ii, Doo-Sup Choi, David W Holdsworth, Maria Drangova, S Jeffrey Dixon, Cheryle A Séguin, James R Hammond. Loss of equilibrative nucleoside transporter 1 in mice leads to progressive ectopic mineralization of spinal tissues resembling diffuse idiopathic skeletal hyperostosis in humans.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2013 May; 28(5):1135-49. doi:
10.1002/jbmr.1826. [PMID: 23184610] - Chong Ghee Chew, Steve Unger, Sepehr Shakib. Value of myocardial perfusion imaging in renal transplant evaluation.
Nephrology (Carlton, Vic.).
2013 May; 18(5):376-81. doi:
10.1111/nep.12050. [PMID: 23490219] - Elliot Offman, Michael J Schobelock, Rolf Brickl, Cam P VanderMaelen, Jerome Ehrlich, Wolfgang Eisert. Pharmacokinetics and pharmacodynamics of the antiplatelet combination aspirin (acetylsalicylic acid) plus extended-release dipyridamole are not altered by coadministration with the potent CYP2C19 inhibitor omeprazole.
American journal of cardiovascular drugs : drugs, devices, and other interventions.
2013 Apr; 13(2):113-20. doi:
10.1007/s40256-013-0018-3. [PMID: 23532686] - W O Tobin, J A Kinsella, G F Kavanagh, J S O'Donnell, R A McGrath, D R Collins, T Coughlan, D O'Neill, B Egan, S Tierney, T M Feeley, R P Murphy, Dominick J H McCabe. Longitudinal assessment of thrombin generation potential in response to alteration of antiplatelet therapy after TIA or ischaemic stroke.
Journal of neurology.
2013 Feb; 260(2):590-6. doi:
10.1007/s00415-012-6684-2. [PMID: 23064666] - Yoshiharu Suzuki, Masato Homma, Masato Abei, Ichinosuke Hyodo, Yukinao Kohda. Effects of dipyridamole coadministration on the pharmacokinetics of ribavirin in healthy volunteers.
Drug metabolism and pharmacokinetics.
2013; 28(5):406-10. doi:
10.2133/dmpk.dmpk-12-rg-137. [PMID: 23459628] - Aysun Caltik, Gülay Demircin, Mehmet Bülbül, Ozlem Erdogan, Sare G Akyüz, Nilüfer Arda. An unusual case of ANA negative systemic lupus erythematosus presented with vasculitis, long-standing serositis and full-house nephropathy.
Rheumatology international.
2013 Jan; 33(1):219-22. doi:
10.1007/s00296-010-1540-0. [PMID: 20532511] - Dimitrios Psachoulias, Maria Vertzoni, James Butler, David Busby, Moira Symillides, Jennifer Dressman, Christos Reppas. An in vitro methodology for forecasting luminal concentrations and precipitation of highly permeable lipophilic weak bases in the fasted upper small intestine.
Pharmaceutical research.
2012 Dec; 29(12):3486-98. doi:
10.1007/s11095-012-0844-z. [PMID: 22890986] - Danilo Neglia, Tiziana Sampietro, Cecilia Vecoli, Riccardo Liga, Giuseppe Rossi, Elena Filidei, Federico Bigazzi, Patricia Iozzo, Daniela Giannessi, Antonio L'Abbate, Daniele Rovai. Abnormal glucose and lipid control in non-ischemic left ventricular dysfunction.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
2012 Dec; 19(6):1182-9. doi:
10.1007/s12350-012-9609-7. [PMID: 22879076] - Victor Serebruany, Yanti Sani, Ilya Pokov, Alex Schevchuck, Alan Fong, Lionel Thevathasan, Dan Hanley. Effects of extended-release dipyridamole in vitro on thrombin indices measured by calibrated automated thrombography in poststroke survivors.
American journal of therapeutics.
2012 Nov; 19(6):407-12. doi:
10.1097/mjt.0b013e318209e021. [PMID: 21317617] - Ivan Ivanov, Dora Zlatareva, Iliyana Pacheva, Margarita Panova. Does lenticulostriate vasculopathy predipose to ischemic brain infarct? A case report.
Journal of clinical ultrasound : JCU.
2012 Nov; 40(9):607-10. doi:
10.1002/jcu.21922. [PMID: 22505315] - Yi Luo, Payal Rana, Yvonne Will. Palmitate increases the susceptibility of cells to drug-induced toxicity: an in vitro method to identify drugs with potential contraindications in patients with metabolic disease.
Toxicological sciences : an official journal of the Society of Toxicology.
2012 Oct; 129(2):346-62. doi:
10.1093/toxsci/kfs208. [PMID: 22700542] - Xiao-Mei Tao, Jian-cheng Wang, Jia-bao Wang, Qiang Feng, Shan-yun Gao, Liang-Ren Zhang, Qiang Zhang. Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2012 Oct; 82(2):401-9. doi:
10.1016/j.ejpb.2012.06.007. [PMID: 22728546] - Chika Taniguchi, Ryo Inoue, Yohei Kawabata, Kazuhiro Yamashita, Koichi Wada, Yukinori Yamauchi, Shizuo Yamada, Satomi Onoue. Novel formulations of dipyridamole with microenvironmental pH-modifiers for improved dissolution and bioavailability under hypochlorhydria.
International journal of pharmaceutics.
2012 Sep; 434(1-2):148-54. doi:
10.1016/j.ijpharm.2012.05.040. [PMID: 22643223] - I J Frame, Emilio F Merino, Vern L Schramm, María B Cassera, Myles H Akabas. Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity.
The Biochemical journal.
2012 Sep; 446(2):179-90. doi:
10.1042/bj20112220. [PMID: 22670848] - L Barry Seltz, Leigh Anne Bakel, Jennifer Tiehen, Dexiang Gao, Melissa A Cadnapaphornchai, Gary Lum, Douglas Ford. Efficacy and safety of clopidogrel in children with diarrhea associated hemolytic uremic syndrome.
Thrombosis research.
2012 Sep; 130(3):e26-30. doi:
10.1016/j.thromres.2012.05.017. [PMID: 22683020] - Osama F Harraz, Hanan M El-Gowelli, Mahmoud M Mohy El-Din, Abdel-Rheem M Ghazal, Mahmoud M El-Mas. Adenosinergic modulation of the imidazoline I₁-receptor-dependent hypotensive effect of ethanol in acute renal failure.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Aug; 50(8):2622-8. doi:
10.1016/j.fct.2012.05.015. [PMID: 22613216] - Horace T B Ho, Li Xia, Joanne Wang. Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activity and sensitivity to inhibition by dilazep.
Biochemical pharmacology.
2012 Aug; 84(3):383-90. doi:
10.1016/j.bcp.2012.04.018. [PMID: 22562044] - Graeme J Hankey, John W Eikelboom, Qilong Yi, Kennedy R Lees, Christopher Chen, Denis Xavier, Jose C Navarro, Udaya K Ranawaka, Wasim Uddin, Stefano Ricci, John Gommans, Reinhold Schmidt. Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial.
The Lancet. Neurology.
2012 Jun; 11(6):512-20. doi:
10.1016/s1474-4422(12)70091-1. [PMID: 22554931] - Wilbert S Aronow. Peripheral arterial disease of the lower extremities.
Archives of medical science : AMS.
2012 May; 8(2):375-88. doi:
10.5114/aoms.2012.28568. [PMID: 22662015] - Michael Allon, Li Zhang, Ivan D Maya, Molly S Bray, Jose R Fernandez. Association of factor V gene polymorphism with arteriovenous graft failure.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2012 May; 59(5):682-8. doi:
10.1053/j.ajkd.2011.11.036. [PMID: 22281051] - Qiang Lin, Yue Min, Yanhong Li, Yun Zhu, Xiaoxiang Song, Qinying Xu, Lifeng Wang, Jiang Cheng, Qihua Feng, Xiaozhong Li. Henoch-Schönlein purpura with hypocomplementemia.
Pediatric nephrology (Berlin, Germany).
2012 May; 27(5):801-6. doi:
10.1007/s00467-011-2070-z. [PMID: 22271365] - Karthik Ananthasubramaniam, Robert Weiss, Bruce McNutt, Barbara Klauke, Kathleen Feaheny, Stan Bukofzer. A randomized, double-blind, placebo-controlled study of the safety and tolerance of regadenoson in subjects with stage 3 or 4 chronic kidney disease.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
2012 Apr; 19(2):319-29. doi:
10.1007/s12350-011-9508-3. [PMID: 22259009] - Elena Guillén-Gómez, Itziar Pinilla-Macua, Sandra Pérez-Torras, Doo-Sup Choi, Yolanda Arce, José A Ballarín, Marçal Pastor-Anglada, Montserrat M Díaz-Encarnación. New role of the human equilibrative nucleoside transporter 1 (hENT1) in epithelial-to-mesenchymal transition in renal tubular cells.
Journal of cellular physiology.
2012 Apr; 227(4):1521-8. doi:
10.1002/jcp.22869. [PMID: 21678404] - Mona M Soliman, Maha M Arafah. Treatment with dipyridamole improves cardiac function and prevent injury in a rat model of hemorrhage.
European journal of pharmacology.
2012 Mar; 678(1-3):26-31. doi:
10.1016/j.ejphar.2011.12.038. [PMID: 22227379] - Joel M Weinberg, Manjeri A Venkatachalam. Preserving postischemic reperfusion in the kidney: a role for extracellular adenosine.
The Journal of clinical investigation.
2012 Feb; 122(2):493-6. doi:
10.1172/jci60957. [PMID: 22269321] - Sergey V Brodsky, Brad H Rovin, Lee A Hebert. Benefit of cyclophosphamide therapy in IgA nephritis may have been obscured by warfarin-related nephropathy in the randomized trials in which warfarin and dipyridamole were used in combination with cyclophosphamide.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2012 Feb; 27(2):475-7. doi:
10.1093/ndt/gfr559. [PMID: 21948859]