Anemonin (BioDeep_00000015689)

 

Secondary id: BioDeep_00001869938

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Pulsatilla camphor

化学式: C10H8O4 (192.0423)
中文名称: 白头翁素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC2(C13C=CC(=O)O3)C=CC(=O)O2
InChI: InChI=1S/C10H8O4/c11-7-1-3-9(13-7)5-6-10(9)4-2-8(12)14-10/h1-4H,5-6H2/t9-,10-/m1/s1

描述信息

同义名列表

4 个代谢物同义名

Anemonin; Pulsatilla camphor; Anemonine; Anemonin



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

33 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Betelhem Sirak, Gizachew Kassahun Bizuneh, Peter Imming, Kaleab Asres. In vitro and in vivo antitrypanosomal activity of the fresh leaves of Ranunculus Multifidus Forsk and its major compound anemonin against Trypanosoma congolense field isolate. BMC veterinary research. 2024 Jan; 20(1):32. doi: 10.1186/s12917-023-03856-1. [PMID: 38279149]
  • Betelhem Sirak, Kaleab Asres, Asrat Hailu, Mthandazo Dube, Norbert Arnold, Cecile Häberli, Jennifer Keiser, Peter Imming. In Vitro Antileishmanial and Antischistosomal Activities of Anemonin Isolated from the Fresh Leaves of Ranunculus multifidus Forsk. Molecules (Basel, Switzerland). 2021 Dec; 26(24):. doi: 10.3390/molecules26247473. [PMID: 34946555]
  • Betelhem Sirak, Lea Mann, Adrian Richter, Kaleab Asres, Peter Imming. In Vivo Antimalarial Activity of Leaf Extracts and a Major Compound Isolated from Ranunculus multifidus Forsk. Molecules (Basel, Switzerland). 2021 Oct; 26(20):. doi: 10.3390/molecules26206179. [PMID: 34684762]
  • Lingyan Qiao, Yusheng Liu, Cheng Li, Juan Ge, Tang Li. Regulation of iRhom-2/Tumor Necrosis Factor-α Converting Enzyme Pathway and Oxidative Stress Protects the Renal Injury with Anemonin in Streptozotocin-Induced Diabetic Nephropathy Neonatal Rat Model. Pharmacology. 2019; 104(5-6):258-266. doi: 10.1159/000501631. [PMID: 31344701]
  • Teodora Neag, Neli-Kinga Olah, Daniela Hanganu, Daniela Benedec, Flavia Furtuna Pripon, Aurel Ardelean, Claudia Crina Toma. The anemonin content of four different Ranunculus species. Pakistan journal of pharmaceutical sciences. 2018 Sep; 31(5(Supplementary)):2027-2032. doi: . [PMID: 30393208]
  • Zuqiang Wang, Junlan Huang, Siru Zhou, Fengtao Luo, Wei Xu, Quan Wang, Qiaoyan Tan, Liang Chen, Jun Wang, Hangang Chen, Lin Chen, Yangli Xie, Xiaolan Du. Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL-1β/NF-κB pathway. Journal of cellular and molecular medicine. 2017 Dec; 21(12):3231-3243. doi: 10.1111/jcmm.13227. [PMID: 28643466]
  • Dong Jia, Bin Han, Shaowei Yang, Junying Zhao. Anemonin alleviates nerve injury after cerebral ischemia and reperfusion (i/r) in rats by improving antioxidant activities and inhibiting apoptosis pathway. Journal of molecular neuroscience : MN. 2014 Jun; 53(2):271-9. doi: 10.1007/s12031-013-0217-z. [PMID: 24443273]
  • Rakesh Chawla, Suresh Kumar, Anupam Sharma. The genus Clematis (Ranunculaceae): chemical and pharmacological perspectives. Journal of ethnopharmacology. 2012 Aug; 143(1):116-50. doi: 10.1016/j.jep.2012.06.014. [PMID: 22728167]
  • Nicoleta G Hădărugă. Ficaria verna Huds. extracts and their β-cyclodextrin supramolecular systems. Chemistry Central journal. 2012 Mar; 6(1):16. doi: 10.1186/1752-153x-6-16. [PMID: 22390207]
  • Sabreen F Fostok, Rima A Ezzeddine, Fadia R Homaidan, Jamal A Al-Saghir, Ralph G Salloum, Najat A Saliba, Rabih S Talhouk. Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus. BMC complementary and alternative medicine. 2009 Nov; 9(?):44. doi: 10.1186/1472-6882-9-44. [PMID: 19917107]
  • Yiyi Hu, Xi Chen, Huiqin Duan, Yuanliang Hu, Xiang Mu. Pulsatilla decoction and its active ingredients inhibit secretion of NO, ET-1, TNF-alpha, and IL-1 alpha in LPS-induced rat intestinal microvascular endothelial cells. Cell biochemistry and function. 2009 Jul; 27(5):284-8. doi: 10.1002/cbf.1570. [PMID: 19472295]
  • Tzong Huei Lee, Nai Kuei Huang, Tzi Chung Lai, Aleck T Y Yang, Guei Jane Wang. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. Journal of ethnopharmacology. 2008 Mar; 116(3):518-27. doi: 10.1016/j.jep.2007.12.019. [PMID: 18281171]
  • Yen-Hua Huang, Tzong-Huei Lee, Kuei-Jung Chan, Feng-Lin Hsu, Yu-Chih Wu, Mei-Hsien Lee. Anemonin is a natural bioactive compound that can regulate tyrosinase-related proteins and mRNA in human melanocytes. Journal of dermatological science. 2008 Feb; 49(2):115-23. doi: 10.1016/j.jdermsci.2007.07.008. [PMID: 17766092]
  • Cai-Xi Dong, She-Po Shi, Ke-Si Wu, Peng-Fei Tu. [Studies on chemical constituents from root of Clematis hexapetala]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Oct; 31(20):1696-9. doi: ". [PMID: 17225539]
  • Cheryl Lans, Nancy Turner, Gerhard Brauer, Grant Lourenco, Karla Georges. Ethnoveterinary medicines used for horses in Trinidad and in British Columbia, Canada. Journal of ethnobiology and ethnomedicine. 2006 Aug; 2(?):31. doi: 10.1186/1746-4269-2-31. [PMID: 16893454]
  • Wei Zheng, Chang-xin Zhou, Shui-li Zhang, Lin-jia Weng, Yu Zhao. [Studies on the chemical constituents in herb of Ranunculus japonicus]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Jun; 31(11):892-4. doi: ". [PMID: 17048626]
  • Jose M Prieto, Tiziana Siciliano, Alessandra Braca. A new acylated quercetin glycoside and other secondary metabolites from Helleborus foetidus. Fitoterapia. 2006 Apr; 77(3):203-7. doi: 10.1016/j.fitote.2006.01.012. [PMID: 16545528]
  • Ying Zhou, Shixi Hu, Shiqing Hu, Guangyi Liang. [Study on peparation of anemonin from Ranunculus japonicus Thunb]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2004 Oct; 27(10):762-4. doi: ". [PMID: 15850359]
  • M L Martin, A V Ortíz de Urbina, M J Montero, R Carrón, L San Román. Pharmacologic effects of lactones isolated from Pulsatilla alpina subsp. apiifolia. Journal of ethnopharmacology. 1988 Dec; 24(2-3):185-91. doi: 10.1016/0378-8741(88)90150-x. [PMID: 3267028]
  • J R Kern, J H Cardellina. Native American medicinal plants. Anemonin from the horse stimulant Clematis hirsutissima. Journal of ethnopharmacology. 1983 Jul; 8(1):121-3. doi: 10.1016/0378-8741(83)90093-4. [PMID: 6632934]
  • J S Li, P G Xiao, Z Q Lou. [Botanical and pharmacognostical studies of the Chinese drug Wei-ling-xian (author's transl)]. Yao xue xue bao = Acta pharmaceutica Sinica. 1980 May; 15(5):288-97. doi: ". [PMID: 6969970]