Cefalotin sodium (BioDeep_00000015168)
Secondary id: BioDeep_00001868434
代谢物信息卡片
Cephalothin Sodium
化学式: C16H15N2NaO6S2 (418.026921)
中文名称: 先锋霉素 钠盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
InChI: /q
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
2 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:3542
- KEGG: C08100
- KEGGdrug: D00907
- PubChem: 23675321
- Metlin: METLIN66817
- ChEMBL: CHEMBL1632
- MeSH: Cephalothin
- CAS: 58-71-9
- PubChem: 10300
- NIKKAJI: J66.407C
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Patrícia Aleixa do Nascimento, Ana Carolina Kogawa, Hérida Regina Nunes Salgado. Cephalothin: Review of Characteristics, Properties, and Status of Analytical Methods.
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10.1128/jcm.23.6.1068-1071.1986. [PMID: 3086375] - M H Kroll, R Chesler, C Hagengruber, D W Blank, J Kestner, M Rawe. Automated determination of urinary creatinine without sample dilution: theory and practice.
Clinical chemistry.
1986 Mar; 32(3):446-52. doi:
10.1093/clinchem/32.3.446. [PMID: 3948388] - R W Lacey, K W Barr, V E Barr, T J Inglis. Properties of methicillin-resistant Staphylococcus aureus colonizing patients in a burns unit.
The Journal of hospital infection.
1986 Mar; 7(2):137-48. doi:
10.1016/0195-6701(86)90056-3. [PMID: 2871076] - K Ohashi, M Tsunoo, K Tsuneoka. Pharmacokinetics and protein binding of cefazolin and cephalothin in patients with cirrhosis.
The Journal of antimicrobial chemotherapy.
1986 Mar; 17(3):347-51. doi:
10.1093/jac/17.3.347. [PMID: 3700294] - P Van der Auwera, J Klastersky, S Lieppe, M Husson, D Lauzon, A P Lopez. Bactericidal activity and killing rate of serum from volunteers receiving pefloxacin alone or in combination with amikacin.
Antimicrobial agents and chemotherapy.
1986 Feb; 29(2):230-4. doi:
10.1128/aac.29.2.230. [PMID: 3087276] - C J Hackbarth, H F Chambers, M A Sande. Serum bactericidal titer as a predictor of outcome in endocarditis.
European journal of clinical microbiology.
1986 Feb; 5(1):93-7. doi:
10.1007/bf02013476. [PMID: 2938947] - J van Crugten, F Bochner, J Keal, A Somogyi. Selectivity of the cimetidine-induced alterations in the renal handling of organic substrates in humans. Studies with anionic, cationic and zwitterionic drugs.
The Journal of pharmacology and experimental therapeutics.
1986 Feb; 236(2):481-7. doi:
NULL. [PMID: 3944769] - M G Bergeron, Y Bergeron. Influence of endotoxin on the intrarenal distribution of gentamicin, netilmicin, tobramycin, amikacin, and cephalothin.
Antimicrobial agents and chemotherapy.
1986 Jan; 29(1):7-12. doi:
10.1128/aac.29.1.7. [PMID: 3524424] - H Goris, F de Boer, D van der Waaij. Oral administration of antibiotics and intestinal flora associated endotoxin in mice.
Scandinavian journal of infectious diseases.
1986; 18(1):55-63. doi:
10.3109/00365548609032307. [PMID: 3008311] - G Letellier, F Desjarlais. Analytical interference of drugs in clinical chemistry: II--The interference of three cephalosporins with the determination of serum creatinine concentration by the Jaffé reaction.
Clinical biochemistry.
1985 Dec; 18(6):352-6. doi:
10.1016/s0009-9120(85)80074-6. [PMID: 4092352] - N F Adkinson, A Saxon, M R Spence, E A Swabb. Cross-allergenicity and immunogenicity of aztreonam.
Reviews of infectious diseases.
1985 Nov; 7 Suppl 4(?):S613-21. doi:
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American journal of veterinary research.
1985 Oct; 46(10):2085-90. doi:
NULL. [PMID: 4062011] - J A Gregg, L Maher, P C DeGirolami, J A Gregg. Secretion of beta-lactam antibiotics in pure human pancreatic juice.
American journal of surgery.
1985 Sep; 150(3):333-5. doi:
10.1016/0002-9610(85)90073-x. [PMID: 4037192] - T W Steele, N Sangster, J A Lanser. DNA relatedness and biochemical features of Campylobacter spp. isolated in central and South Australia.
Journal of clinical microbiology.
1985 Jul; 22(1):71-4. doi:
10.1128/jcm.22.1.71-74.1985. [PMID: 2991331] - P D Williams, M J Hitchcock, G H Hottendorf. Effect of cephalosporins on organic ion transport in renal membrane vesicles from rat and rabbit kidney cortex.
Research communications in chemical pathology and pharmacology.
1985 Mar; 47(3):357-71. doi:
NULL. [PMID: 2986254] - E V Gagaeva, A A Firsov, G G Egorenko, E K Berezina, L A Shtegel'man. [Decrease of sisomicin nephrotoxicity as affected by cephalothin: pharmacokinetic evaluation].
Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology.
1985 Mar; 30(3):190-6. doi:
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Zentralblatt fur Gynakologie.
1985; 107(2):90-7. doi:
NULL. [PMID: 2859721] - R Platt, B Rosner. Effect of hydrogen ion and protein concentrations on the activity of beta-lactam antibiotics.
Reviews of infectious diseases.
1984 Nov; 6 Suppl 4(?):S829-34. doi:
10.1093/clinids/6.supplement_4.s829. [PMID: 6522925] - V I Bobrov, G T Beletskaia, V P Iakovlev. [Pharmacodynamics of cephaloridine and cephalothin combined with sulfalene in rabbits].
Antibiotiki.
1984 Nov; 29(11):823-5. doi:
NULL. [PMID: 6524880] - R L Baker, R J Fass. Correlation of in vitro activities of cephalothin and ceftazidime with their efficacies in the treatment of Staphylococcus aureus endocarditis in rabbits.
Antimicrobial agents and chemotherapy.
1984 Aug; 26(2):231-4. doi:
10.1128/aac.26.2.231. [PMID: 6385840] - A Balogh, G Peiker, G Finke, A Traeger. [Urinary enzyme excretion in cephalothin therapy in adults and children].
Zeitschrift fur Urologie und Nephrologie.
1984 Jul; 77(7):425-35. doi:
NULL. [PMID: 6148821] - M O Decroix, J C Chaumeil, B Flouvat. Binding of cefalotin to human serum albumin.
European journal of drug metabolism and pharmacokinetics.
1984 Jul; 9(3):191-4. doi:
10.1007/bf03189640. [PMID: 6519120] - A S Bayer, R Eisenstadt, J O Morrison. Enhanced in vitro bactericidal activity of amikacin or gentamicin combined with three new extended-spectrum cephalosporins against cephalothin-resistant members of the family Enterobacteriaceae.
Antimicrobial agents and chemotherapy.
1984 Jun; 25(6):725-8. doi:
10.1128/aac.25.6.725. [PMID: 6331297] - L Swanberg, C U Tuazon. Rifampin in the treatment of serious staphylococcal infections.
The American journal of the medical sciences.
1984 May; 287(3):49-54. doi:
10.1097/00000441-198405000-00018. [PMID: 6563847] - Y Sato, H Kanazawa, H Okazaki, T Kosuge, K Imaizumi, S Eguchi. [A comparison of the penetration characteristics of latamoxef and cephalothin into the right atrial appendage and pericardial fluid of adult patients undergoing open-heart surgery].
The Japanese journal of antibiotics.
1984 Apr; 37(4):671-9. doi:
. [PMID: 6471383] - A Nakagawa, M Araki, T Ohshima, Y Ueno, K Sakamoto, M Akagi. Investigation of the CET levels in the serum during and after cardiopulmonary bypass.
Nihon geka hokan. Archiv fur japanische Chirurgie.
1984 Mar; 53(2):306-11. doi:
NULL. [PMID: 6508460] - B Wiedemann, A H Seeberg. The activity of cefotiam on beta-lactamase-producing bacteria in an in-vitro model.
The Journal of antimicrobial chemotherapy.
1984 Feb; 13(2):111-9. doi:
10.1093/jac/13.2.111. [PMID: 6323374]