Cefalotin sodium (BioDeep_00000015168)
Secondary id: BioDeep_00001868434
代谢物信息卡片
Cephalothin Sodium
化学式: C16H15N2NaO6S2 (418.0269)
中文名称: 先锋霉素 钠盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
InChI: /q
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
3 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:3542
- KEGG: C08100
- KEGGdrug: D00907
- PubChem: 23675321
- Metlin: METLIN66817
- ChEMBL: CHEMBL1632
- MeSH: Cephalothin
- CAS: 58-71-9
- PubChem: 10300
- NIKKAJI: J66.407C
- KNApSAcK: 3542
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Patrícia Aleixa do Nascimento, Ana Carolina Kogawa, Hérida Regina Nunes Salgado. Cephalothin: Review of Characteristics, Properties, and Status of Analytical Methods.
Journal of AOAC International.
2021 Dec; 104(6):1593-1608. doi:
10.1093/jaoacint/qsaa163. [PMID: 33252646] - Taisuke Kuroda, Yohei Minamijima, Hidekazu Niwa, Norihisa Tamura, Hiroshi Mita, Kentaro Fukuda, Masahiro Kaimachi, Yuto Suzuki, Yuki Enoki, Kazuaki Taguchi, Kazuaki Matsumoto, Pierre-Louis Toutain, Alain Bousquet-Melou, Yoshinori Kasashima. Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses.
Equine veterinary journal.
2021 Nov; 53(6):1239-1249. doi:
10.1111/evj.13406. [PMID: 33341979] - Zhengyu Zhang, Masanori Tachikawa, Yasuo Uchida, Tetsuya Terasaki. Drug Clearance from Cerebrospinal Fluid Mediated by Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) at Arachnoid Membrane of Rats.
Molecular pharmaceutics.
2018 03; 15(3):911-922. doi:
10.1021/acs.molpharmaceut.7b00852. [PMID: 29436232] - Valerie Corvalán, Beatrice Hervé, Camila Sanhueza, Nicolás Martínez, María Almonacid, Sebastián De La Fuente. [Susceptibility to first-generation Cephalosporins in Enterobacteriaceae isolated from urine culture according to CLSI and EUCAST breakpoints].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia.
2018 ; 35(3):329-331. doi:
10.4067/s0716-10182018000300329. [PMID: 30534916] - Darren M Roberts, Dwarakanathan Ranganathan, Steven C Wallis, Julie M Varghese, Adrian Kark, Jeffrey Lipman, Jason A Roberts. Pharmacokinetics of Intraperitoneal Cefalothin and Cefazolin in Patients Being Treated for Peritoneal Dialysis-Associated Peritonitis.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2016 Jul; 36(4):415-20. doi:
10.3747/pdi.2015.00008. [PMID: 26764340] - Suzanne L Parker, Yarmarly C Guerra Valero, Darren M Roberts, Jeffrey Lipman, Jason A Roberts, Steven C Wallis. Determination of Cefalothin and Cefazolin in Human Plasma, Urine and Peritoneal Dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans.
Biomedical chromatography : BMC.
2016 Jun; 30(6):872-9. doi:
10.1002/bmc.3622. [PMID: 26394804] - Loreto Manosalva, Ana Mutis, Alejandro Urzúa, Victor Fajardo, Andrés Quiroz. Antibacterial Activity of Alkaloid Fractions from Berberis microphylla G. Forst and Study of Synergism with Ampicillin and Cephalothin.
Molecules (Basel, Switzerland).
2016 Jan; 21(1):76. doi:
10.3390/molecules21010076. [PMID: 26760994] - André Pitondo-Silva, Gerson Nakazato, Juliana P Falcão, Kinue Irino, Roberto Martinez, Ana Lúcia C Darini, Rodrigo Tavanelli Hernandes. Phenotypic and genetic features of enteropathogenic Escherichia coli isolates from diarrheal children in the Ribeirão Preto metropolitan area, São Paulo State, Brazil.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
2015 Feb; 123(2):128-35. doi:
10.1111/apm.12314. [PMID: 25257819] - Isoken Henrietta Igbinosa. Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals.
Tropical animal health and production.
2015 Jan; 47(1):37-43. doi:
10.1007/s11250-014-0680-8. [PMID: 25348646] - Alper Otunctemur, Emin Ozbek, Emre Can Polat, Mustafa Cekmen, Murat Dursun, Suleyman Sami Cakir. Increasing urinary calcium excretion after ceftriaxone and cephalothin therapy in adults: possible association with urolithiasis.
Urolithiasis.
2014 Apr; 42(2):105-8. doi:
10.1007/s00240-013-0627-y. [PMID: 24310104] - Morike Ngoe Mokube, Julius Atashili, Gregory Edie Halle-Ekane, George M Ikomey, Peter M Ndumbe. Bacteriuria amongst pregnant women in the Buea Health District, Cameroon: prevalence, predictors, antibiotic susceptibility patterns and diagnosis.
PloS one.
2013; 8(8):e71086. doi:
10.1371/journal.pone.0071086. [PMID: 23976983] - Ranjana Sharma, Laura Keffer-Wilkes, Ruibing Wu, Jin-Quan Li, Sushil Jacob John, Edward Topp. Enumeration and strain characterization of fecal Escherichia coli associated with feeding triticale dried distillers grain with solubles in beef cattle diets.
Foodborne pathogens and disease.
2010 Nov; 7(11):1323-30. doi:
10.1089/fpd.2010.0557. [PMID: 20707734] - Dongeun Yong, Mark A Toleman, Christian G Giske, Hyun S Cho, Kristina Sundman, Kyungwon Lee, Timothy R Walsh. Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
Antimicrobial agents and chemotherapy.
2009 Dec; 53(12):5046-54. doi:
10.1128/aac.00774-09. [PMID: 19770275] - Andrew J Dalley, Renae Deans, Jeffrey Lipman, Bala Venkatesh, Michael Rudd, Michael S Roberts, Sheree E Cross. Unbound cephalothin pharmacokinetics in adult burn patients are related to the elapsed time after injury.
Antimicrobial agents and chemotherapy.
2009 Dec; 53(12):5303-5. doi:
10.1128/aac.01600-08. [PMID: 19752272] - M José Figueras, Anabel Alperi, M José Saavedra, Wen-Chien Ko, Nieves Gonzalo, Maria Navarro, Antonio J Martínez-Murcia. Clinical relevance of the recently described species Aeromonas aquariorum.
Journal of clinical microbiology.
2009 Nov; 47(11):3742-6. doi:
10.1128/jcm.02216-08. [PMID: 19741075] - Andrew J Dalley, Jeffrey Lipman, Renae Deans, Bala Venkatesh, Michael Rudd, Michael S Roberts, Sheree E Cross. Tissue accumulation of cephalothin in burns: a comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers.
Antimicrobial agents and chemotherapy.
2009 Jan; 53(1):210-5. doi:
10.1128/aac.00718-08. [PMID: 18955521] - Bruce A Wagner, Barbara E Straw, Paula J Fedorka-Cray, David A Dargatz. Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine.
Applied and environmental microbiology.
2008 Mar; 74(6):1731-9. doi:
10.1128/aem.01132-07. [PMID: 18223115] - Andrew J Dalley, Jeffrey Lipman, Bala Venkatesh, Michael Rudd, Michael S Roberts, Sheree E Cross. Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement.
The Journal of antimicrobial chemotherapy.
2007 Jul; 60(1):166-9. doi:
10.1093/jac/dkm128. [PMID: 17504805] - S Carroll, M Hargreaves, A Goonetilleke. Sourcing faecal pollution from onsite wastewater treatment systems in surface waters using antibiotic resistance analysis.
Journal of applied microbiology.
2005; 99(3):471-82. doi:
10.1111/j.1365-2672.2005.02644.x. [PMID: 16108788] - Ahmad H Al-Ghamdi, Mohammed A Al-Shadokhy, Abdulrahman A Al-Warthan. Electrochemical determination of Cephalothin antibiotic by adsorptive stripping voltammetric technique.
Journal of pharmaceutical and biomedical analysis.
2004 Sep; 35(5):1001-9. doi:
10.1016/j.jpba.2004.02.034. [PMID: 15336347] - Sérgio A C Melo, Eduardo A R Castro, Antônio C Ponce-de-Leon, José A A Pereira. Use of selective media for detection of cephalothin-resistant bacteria in surgical patients.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases.
2004 Jun; 8(3):190-6. doi:
10.1590/s1413-86702004000300001. [PMID: 15476050] - A J Matute, E Hak, C A M Schurink, A McArthur, E Alonso, M Paniagua, E Van Asbeck, A M Roskott, F Froeling, M Rozenberg-Arska, I M Hoepelman. Resistance of uropathogens in symptomatic urinary tract infections in León, Nicaragua.
International journal of antimicrobial agents.
2004 May; 23(5):506-9. doi:
10.1016/j.ijantimicag.2003.10.003. [PMID: 15120732] - Suparat Khamdang, Michio Takeda, Ellappan Babu, Rie Noshiro, Maristela Lika Onozato, Akihiro Tojo, Atsushi Enomoto, Xiu-Lin Huang, Shinichi Narikawa, Naohiko Anzai, Pawinee Piyachaturawat, Hitoshi Endou. Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.
European journal of pharmacology.
2003 Mar; 465(1-2):1-7. doi:
10.1016/s0014-2999(03)01381-5. [PMID: 12650826] - Patricia A Arndt, George Garratty. Cross-reactivity of cefotetan and ceftriaxone antibodies, associated with hemolytic anemia, with other: cephalosporins and penicillin.
American journal of clinical pathology.
2002 Aug; 118(2):256-62. doi:
10.1309/jfje-vukn-221t-g6ev. [PMID: 12162687] - Michio Takeda, Ellappan Babu, Shinichi Narikawa, Hitoshi Endou. Interaction of human organic anion transporters with various cephalosporin antibiotics.
European journal of pharmacology.
2002 Mar; 438(3):137-42. doi:
10.1016/s0014-2999(02)01306-7. [PMID: 11909604] - M Takeuchi, M Harada, M Nagata, A Watanabe, K Nakamura. [Immunological properties of S-1090, cefmatilen hydrochloride hydrate].
The Journal of toxicological sciences.
2001 May; 26 Suppl 1(?):231-42. doi:
NULL. [PMID: 11400315] - S G Mulamattathil, H A Esterhuysen, P J Pretorius. Antibiotic-resistant gram-negative bacteria in a virtually closed water reticulation system.
Journal of applied microbiology.
2000 Jun; 88(6):930-7. doi:
10.1046/j.1365-2672.2000.01052.x. [PMID: 10849168] - J H Simmons, L K Riley, C L Besch-Williford, C L Franklin. Helicobacter mesocricetorum sp. nov., A novel Helicobacter isolated from the feces of Syrian hamsters.
Journal of clinical microbiology.
2000 May; 38(5):1811-7. doi:
10.1128/jcm.38.5.1811-1817.2000. [PMID: 10790105] - Y Matsuda, S Hobo, H Naito. Transferability of cephalothin to the alveolar cavity in thoroughbreds.
The Journal of veterinary medical science.
1999 Mar; 61(3):209-12. doi:
10.1292/jvms.61.209. [PMID: 10331190] - I E Dyer, T M Sankary, J A Dawson. Antibiotic resistance in bacterial urinary tract infections, 1991 to 1997.
The Western journal of medicine.
1998 Nov; 169(5):265-8. doi:
NULL. [PMID: 9830353] - C M Sedgley, L P Samaranayake. Antimicrobial susceptibility of oral isolates of Enterobacter cloacae and Klebsiella pneumoniae from a southern Chinese population.
Oral microbiology and immunology.
1998 Oct; 13(5):315-21. doi:
10.1111/j.1399-302x.1998.tb00713.x. [PMID: 9807124] - R A Musmanno, M Russi, N Figura, P Guglielmetti, A Zanchi, R Signori, A Rossolini. Unusual species of campylobacters isolated in the Siena Tuscany area, Italy.
The new microbiologica.
1998 Jan; 21(1):15-22. doi:
NULL. [PMID: 9497925] - J S Park, I H Choi, D G Lee, S S Han, T Y Ha, J H Lee, W H Lee, Y M Park, H K Lee. Anti-IL-4 monoclonal antibody prevents antibiotics-induced active fatal anaphylaxis.
Journal of immunology (Baltimore, Md. : 1950).
1997 May; 158(10):5002-6. doi:
. [PMID: 9144520] - J L Melchor, C Gracida. Prophylactic antibiotics in renal transplantation.
Transplantation proceedings.
1996 Dec; 28(6):3305. doi:
NULL. [PMID: 8962283] - J A Murillo, J M Lemus, L F García. Analysis of binary mixtures of cephalothin and cefoxitin by using first-derivative spectrophotometry.
Journal of pharmaceutical and biomedical analysis.
1996 Jan; 14(3):257-66. doi:
10.1016/0731-7085(95)01600-7. [PMID: 8851749] - S Halligan, S J Byard, A J Spencer, T J Gray, E S Harpur, F W Bonner. A study of the nephrotoxicity of three cephalosporins in rabbits using 1H NMR spectroscopy.
Toxicology letters.
1995 Nov; 81(1):15-21. doi:
10.1016/0378-4274(95)03399-8. [PMID: 8525494] - S W Petersen, E Rosin. Cephalothin and cefazolin in vitro antibacterial activity and pharmacokinetics in dogs.
Veterinary surgery : VS.
1995 Jul; 24(4):347-51. doi:
10.1111/j.1532-950x.1995.tb01341.x. [PMID: 7571387] - S M Sheen-Chen, Y F Cheng, F F Chou, T Y Lee. Postoperative T-tube cholangiography: is routine antibiotic prophylaxis necessary? A prospective, controlled study.
Archives of surgery (Chicago, Ill. : 1960).
1995 Jan; 130(1):20-3. doi:
10.1001/archsurg.1995.01430010022004. [PMID: 7802571] - L H Lash, J J Tokarz, E B Woods. Renal cell type specificity of cephalosporin-induced cytotoxicity in suspensions of isolated proximal tubular and distal tubular cells.
Toxicology.
1994 Nov; 94(1-3):97-118. doi:
10.1016/0300-483x(94)90031-0. [PMID: 7801333] - T Schermerhorn, S C Barr, D A Stoffregen, Y Koren-Roth, H N Erb. Whole-blood platelet aggregation, buccal mucosa bleeding time, and serum cephalothin concentration in dogs receiving a presurgical antibiotic protocol.
American journal of veterinary research.
1994 Nov; 55(11):1602-7. doi:
NULL. [PMID: 7879986] - S H Hartzen, N Frimodt-Møller, V F Thomsen. The antibacterial activity of a siderophore. 3. The activity of deferoxamine in vitro and its influence on the effect of antibiotics against Escherichia coli, Proteus mirabilis and coagulase-negative staphylococci.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
1994 Mar; 102(3):219-26. doi:
NULL. [PMID: 8185889] - S M Sheen-Chen, F F Chou. Postoperative choledochoscopy: is routine antibiotic prophylaxis necessary?--A prospective randomized study.
Surgery.
1994 Feb; 115(2):170-5. doi:
NULL. [PMID: 8310405] - J O Lopes, S H Alves, J P Benevenga, A Salla, I Tatsch. Nocardia asteroides peritonitis during continuous ambulatory peritoneal dialysis.
Revista do Instituto de Medicina Tropical de Sao Paulo.
1993 Jul; 35(4):377-9. doi:
10.1590/s0036-46651993000400013. [PMID: 8115800] - E M Sloand, H G Klein, K B Pastakia, P Pierce, K N Prodouz. Effect of albumin on the inhibition of platelet aggregation by beta-lactam antibiotics.
Blood.
1992 Apr; 79(8):2022-7. doi:
NULL. [PMID: 1562728] - T Terasaki, H Nouda, A Tsuji. Selective analysis of mutual displacement effects at the primary binding sites of phenoxymethylpenicillin and cephalothin bindings to human serum albumin.
Journal of pharmacobio-dynamics.
1992 Mar; 15(3):91-7. doi:
10.1248/bpb1978.15.91. [PMID: 1625169] - A P Burnens, J Nicolet. Detection of Campylobacter upsaliensis in diarrheic dogs and cats, using a selective medium with cefoperazone.
American journal of veterinary research.
1992 Jan; 53(1):48-51. doi:
. [PMID: 1539914] - M Kuroyama, K Kumano, F Tomonaga, T Sakai, S Mashimo. [Protein binding of various cephems in healthy subjects and patients with chronic renal failure].
Nihon Jinzo Gakkai shi.
1991 Aug; 33(8):769-77. doi:
. [PMID: 1770637] - K V Singh, R R Reves, L K Pickering, B E Murray. Comparative in vitro activities of amoxicillin-clavulanic acid, cefuroxime, cephalexin, and cephalothin against trimethoprim-resistant Escherichia coli isolated from stools of children attending day-care centers.
Antimicrobial agents and chemotherapy.
1990 Nov; 34(11):2047-9. doi:
10.1128/aac.34.11.2047. [PMID: 2073095] - T Kimura, N Ishikawa, K Shinkai. [Comparative studies on delayed type hypersensitivity of low-molecular compounds and compound-protein conjugates in rabbits].
Arerugi = [Allergy].
1990 Jul; 39(7):587-94. doi:
NULL. [PMID: 2073139] - V Lonský, J Mand'ák, V Lonská, J Simek, J Kovalský, V Rozsíval, V Brzek. [Serum levels of oxacillin and cephalothin in patients with extracorporeal circulation during surgery].
Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti.
1990 May; 69(5):281-6. doi:
NULL. [PMID: 2136444] - K Salmela, B Eklund, L Kyllönen, H Isoniemi, C Korsbäck, K Höckerstedt, J Ahonen. The effect of intravesically applied antibiotic solution in the prophylaxis of infectious complications of renal transplantation.
Transplant international : official journal of the European Society for Organ Transplantation.
1990 May; 3(1):12-4. doi:
10.1007/bf00333195. [PMID: 2369474] - M K Chan, I K Cheng, W S Ng. A randomized prospective trial of three different regimens of treatment of peritonitis in patients on continuous ambulatory peritoneal dialysis.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
1990 Feb; 15(2):155-9. doi:
10.1016/s0272-6386(12)80513-0. [PMID: 2405653] - S C Predari, A B Abalo, J E Santoianni, A Prado, C M Ribas, A Zucchini. [Peritonitis in continuous ambulatory peritoneal dialysis. Microbiological and clinical evaluation].
Medicina.
1990; 50(2):102-6. doi:
NULL. [PMID: 2101843] - K Joh, T Shibasaki, T Azuma, A Kobayashi, T Miyahara, S Aizawa, N Watanabe. Experimental drug-induced allergic nephritis mediated by antihapten antibody.
International archives of allergy and applied immunology.
1989; 88(3):337-44. doi:
10.1159/000234821. [PMID: 2722256] - A C Seguro, J L Monteiro, A dos S Rocha. [Immediate effect of the administration of a single dose of gentamicin and cephalothin on renal function].
Revista do Hospital das Clinicas.
1988 Jul; 43(4):180-5. doi:
NULL. [PMID: 3249888] - H Morioka, R Yajima, M Inazu, T Kobayashi, T Sakaguchi. [Effect of cefodizime sodium on the kidney function in male rabbits--single and 7-day repeated intravenous administration].
The Journal of toxicological sciences.
1988 Jun; 13 Suppl 1(?):329-60. doi:
10.2131/jts.13.supplementi_329. [PMID: 3172295] - T Hayashi, Y Watanabe, K Kumano, R Kitayama, T Yasuda, I Saikawa, J Katahira, T Kumada, K Shimizu. Protective effect of piperacillin against nephrotoxicity of cephaloridine and gentamicin in animals.
Antimicrobial agents and chemotherapy.
1988 Jun; 32(6):912-8. doi:
10.1128/aac.32.6.912. [PMID: 3415211] - P J Hendry, G C Taichman, S J Taichman, W J Keon. Human myocardial responses to antibiotics: gentamicin, tobramycin and cephalothin.
The Canadian journal of cardiology.
1988 Jun; 4(5):219-22. doi:
NULL. [PMID: 3409104] - Z Bounkhala, C Renard, R Baurain, J Marchand-Brynaert, L Ghosez, P M Tulkens. Coupling products of amino acids to penicillin V and cephalothin: synthesis and susceptibility to carboxypeptidases and lysosomal enzymes.
Journal of medicinal chemistry.
1988 May; 31(5):976-83. doi:
10.1021/jm00400a015. [PMID: 3129562] - J Rubin, C Adair. Nitrogen losses and cephalothin absorption in peritonitis treated by hourly peritoneal dialysis.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
1988 Mar; 11(3):214-9. doi:
10.1016/s0272-6386(88)80152-5. [PMID: 3344744] - A A Firsov, V I Danilova, S V Geodakian. [Data averaging in pharmacokinetic analysis: the population pharmacokinetics of cephalothin and cefazolin].
Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology.
1987 Jul; 32(7):502-8. doi:
NULL. [PMID: 3118794] - S Lowenbraun, N Fox, D Cunitz. Azlocillin, cephalothin, and tobramycin therapy in febrile solid tumor patients with chemotherapy-induced leukopenia.
Cancer.
1987 Jul; 60(1):14-7. doi:
10.1002/1097-0142(19870701)60:1<14::aid-cncr2820600104>3.0.co;2-f. [PMID: 3581029] - F J Eismont, S W Wiesel, C T Brighton, R H Rothman. Antibiotic penetration into rabbit nucleus pulposus.
Spine.
1987 Apr; 12(3):254-6. doi:
10.1097/00007632-198704000-00011. [PMID: 3589822] - J V Uri. A comparison of cefonicid with other beta-lactams regarding the effect of human and mouse sera on antibacterial activity.
Acta microbiologica Hungarica.
1987; 34(1):39-44. doi:
. [PMID: 3630630] - G H Hottendorf, D A Laska, P D Williams, S M Ford. Role of desacetylation in the detoxification of cephalothin in renal cells in culture.
Journal of toxicology and environmental health.
1987; 22(1):101-11. doi:
10.1080/15287398709531054. [PMID: 3612832] - B Rouveix, F Groult, M Levacher. Beta-lactam antibiotics and human lymphocyte function: the in vitro effect on blastogenesis, lymphokine production and suppressor cell functions.
International journal of immunopharmacology.
1987; 9(5):567-75. doi:
10.1016/0192-0561(87)90124-x. [PMID: 2957332] - R Soave, J C Hirsch, E A Salvati, B D Brause, R B Roberts. Comparison of ceforanide and cephalothin prophylaxis in patients undergoing total joint arthroplasty.
Orthopedics.
1986 Dec; 9(12):1657-60. doi:
10.3928/0147-7447-19861201-08. [PMID: 3547369] - K Furuhama, T Onodera. The influence of cephem antibiotics on gentamicin nephrotoxicity in normal, acidotic, dehydrated, and unilaterally nephrectomized rats.
Toxicology and applied pharmacology.
1986 Dec; 86(3):430-6. doi:
10.1016/0041-008x(86)90370-4. [PMID: 3787635] - M G Bergeron, Y Marois. Benefit from high intrarenal levels of gentamicin in the treatment of E. coli pyelonephritis.
Kidney international.
1986 Oct; 30(4):481-7. doi:
10.1038/ki.1986.211. [PMID: 3537452] - U Burchardt, M Franke, J Krauss, A Barth. [Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes].
Zeitschrift fur Urologie und Nephrologie.
1986 Oct; 79(10):587-93. doi:
NULL. [PMID: 2880436] - A Gonzalez Molinello, A C Alonso Gonzalez, E L Mariño, A Dominguez-Gil. Distribution of cephalothin and ceftriaxone into experimental interstitial tissue fluid in rabbits.
Arzneimittel-Forschung.
1986 Jul; 36(7):1082-5. doi:
NULL. [PMID: 3768077] - U Ganzinger, H Schiel, A Georgopoulos, G Gumhold. The utility of diffusion chambers as models for the description of drug disposition.
The Journal of antimicrobial chemotherapy.
1986 Jul; 18(1):93-102. doi:
10.1093/jac/18.1.93. [PMID: 3759726] - S A Wellstood. Direct identification and susceptibility testing by the AutoMicrobic system of gram-negative bacilli from urine specimens.
Journal of clinical microbiology.
1986 Jun; 23(6):1068-71. doi:
10.1128/jcm.23.6.1068-1071.1986. [PMID: 3086375] - M H Kroll, R Chesler, C Hagengruber, D W Blank, J Kestner, M Rawe. Automated determination of urinary creatinine without sample dilution: theory and practice.
Clinical chemistry.
1986 Mar; 32(3):446-52. doi:
10.1093/clinchem/32.3.446. [PMID: 3948388] - R W Lacey, K W Barr, V E Barr, T J Inglis. Properties of methicillin-resistant Staphylococcus aureus colonizing patients in a burns unit.
The Journal of hospital infection.
1986 Mar; 7(2):137-48. doi:
10.1016/0195-6701(86)90056-3. [PMID: 2871076] - K Ohashi, M Tsunoo, K Tsuneoka. Pharmacokinetics and protein binding of cefazolin and cephalothin in patients with cirrhosis.
The Journal of antimicrobial chemotherapy.
1986 Mar; 17(3):347-51. doi:
10.1093/jac/17.3.347. [PMID: 3700294] - P Van der Auwera, J Klastersky, S Lieppe, M Husson, D Lauzon, A P Lopez. Bactericidal activity and killing rate of serum from volunteers receiving pefloxacin alone or in combination with amikacin.
Antimicrobial agents and chemotherapy.
1986 Feb; 29(2):230-4. doi:
10.1128/aac.29.2.230. [PMID: 3087276] - C J Hackbarth, H F Chambers, M A Sande. Serum bactericidal titer as a predictor of outcome in endocarditis.
European journal of clinical microbiology.
1986 Feb; 5(1):93-7. doi:
10.1007/bf02013476. [PMID: 2938947] - J van Crugten, F Bochner, J Keal, A Somogyi. Selectivity of the cimetidine-induced alterations in the renal handling of organic substrates in humans. Studies with anionic, cationic and zwitterionic drugs.
The Journal of pharmacology and experimental therapeutics.
1986 Feb; 236(2):481-7. doi:
NULL. [PMID: 3944769] - M G Bergeron, Y Bergeron. Influence of endotoxin on the intrarenal distribution of gentamicin, netilmicin, tobramycin, amikacin, and cephalothin.
Antimicrobial agents and chemotherapy.
1986 Jan; 29(1):7-12. doi:
10.1128/aac.29.1.7. [PMID: 3524424] - H Goris, F de Boer, D van der Waaij. Oral administration of antibiotics and intestinal flora associated endotoxin in mice.
Scandinavian journal of infectious diseases.
1986; 18(1):55-63. doi:
10.3109/00365548609032307. [PMID: 3008311] - G Letellier, F Desjarlais. Analytical interference of drugs in clinical chemistry: II--The interference of three cephalosporins with the determination of serum creatinine concentration by the Jaffé reaction.
Clinical biochemistry.
1985 Dec; 18(6):352-6. doi:
10.1016/s0009-9120(85)80074-6. [PMID: 4092352] - N F Adkinson, A Saxon, M R Spence, E A Swabb. Cross-allergenicity and immunogenicity of aztreonam.
Reviews of infectious diseases.
1985 Nov; 7 Suppl 4(?):S613-21. doi:
10.1093/clinids/7.supplement_4.s613. [PMID: 4081473] - W W Ruoff, R A Sams. Pharmacokinetics and bioavailability of cephalothin in horse mares.
American journal of veterinary research.
1985 Oct; 46(10):2085-90. doi:
NULL. [PMID: 4062011] - J A Gregg, L Maher, P C DeGirolami, J A Gregg. Secretion of beta-lactam antibiotics in pure human pancreatic juice.
American journal of surgery.
1985 Sep; 150(3):333-5. doi:
10.1016/0002-9610(85)90073-x. [PMID: 4037192] - T W Steele, N Sangster, J A Lanser. DNA relatedness and biochemical features of Campylobacter spp. isolated in central and South Australia.
Journal of clinical microbiology.
1985 Jul; 22(1):71-4. doi:
10.1128/jcm.22.1.71-74.1985. [PMID: 2991331] - P D Williams, M J Hitchcock, G H Hottendorf. Effect of cephalosporins on organic ion transport in renal membrane vesicles from rat and rabbit kidney cortex.
Research communications in chemical pathology and pharmacology.
1985 Mar; 47(3):357-71. doi:
NULL. [PMID: 2986254] - E V Gagaeva, A A Firsov, G G Egorenko, E K Berezina, L A Shtegel'man. [Decrease of sisomicin nephrotoxicity as affected by cephalothin: pharmacokinetic evaluation].
Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology.
1985 Mar; 30(3):190-6. doi:
. [PMID: 4015061] - A Balogh, G Peiker, H Nöschel, A Traeger. [Urinary enzyme excretion in cephalothin therapy in pregnancy].
Zentralblatt fur Gynakologie.
1985; 107(2):90-7. doi:
NULL. [PMID: 2859721] - R Platt, B Rosner. Effect of hydrogen ion and protein concentrations on the activity of beta-lactam antibiotics.
Reviews of infectious diseases.
1984 Nov; 6 Suppl 4(?):S829-34. doi:
10.1093/clinids/6.supplement_4.s829. [PMID: 6522925] - V I Bobrov, G T Beletskaia, V P Iakovlev. [Pharmacodynamics of cephaloridine and cephalothin combined with sulfalene in rabbits].
Antibiotiki.
1984 Nov; 29(11):823-5. doi:
NULL. [PMID: 6524880] - R L Baker, R J Fass. Correlation of in vitro activities of cephalothin and ceftazidime with their efficacies in the treatment of Staphylococcus aureus endocarditis in rabbits.
Antimicrobial agents and chemotherapy.
1984 Aug; 26(2):231-4. doi:
10.1128/aac.26.2.231. [PMID: 6385840] - A Balogh, G Peiker, G Finke, A Traeger. [Urinary enzyme excretion in cephalothin therapy in adults and children].
Zeitschrift fur Urologie und Nephrologie.
1984 Jul; 77(7):425-35. doi:
NULL. [PMID: 6148821] - M O Decroix, J C Chaumeil, B Flouvat. Binding of cefalotin to human serum albumin.
European journal of drug metabolism and pharmacokinetics.
1984 Jul; 9(3):191-4. doi:
10.1007/bf03189640. [PMID: 6519120] - A S Bayer, R Eisenstadt, J O Morrison. Enhanced in vitro bactericidal activity of amikacin or gentamicin combined with three new extended-spectrum cephalosporins against cephalothin-resistant members of the family Enterobacteriaceae.
Antimicrobial agents and chemotherapy.
1984 Jun; 25(6):725-8. doi:
10.1128/aac.25.6.725. [PMID: 6331297] - L Swanberg, C U Tuazon. Rifampin in the treatment of serious staphylococcal infections.
The American journal of the medical sciences.
1984 May; 287(3):49-54. doi:
10.1097/00000441-198405000-00018. [PMID: 6563847] - Y Sato, H Kanazawa, H Okazaki, T Kosuge, K Imaizumi, S Eguchi. [A comparison of the penetration characteristics of latamoxef and cephalothin into the right atrial appendage and pericardial fluid of adult patients undergoing open-heart surgery].
The Japanese journal of antibiotics.
1984 Apr; 37(4):671-9. doi:
. [PMID: 6471383] - A Nakagawa, M Araki, T Ohshima, Y Ueno, K Sakamoto, M Akagi. Investigation of the CET levels in the serum during and after cardiopulmonary bypass.
Nihon geka hokan. Archiv fur japanische Chirurgie.
1984 Mar; 53(2):306-11. doi:
NULL. [PMID: 6508460] - B Wiedemann, A H Seeberg. The activity of cefotiam on beta-lactamase-producing bacteria in an in-vitro model.
The Journal of antimicrobial chemotherapy.
1984 Feb; 13(2):111-9. doi:
10.1093/jac/13.2.111. [PMID: 6323374]
